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Select item 111361081.

Tribbles: novel regulators of cell function; evolutionary aspects

Z. Hegedus, A. Czibula, E. Kiss-Toth

Cell Mol Life Sci. 2006 Jul; 63(14): 1632–1641. Published online 2006 May 22. doi: 10.1007/s00018-006-6007-9

PMCID:: PMC11136108

Abstract Article PDF–2.8M

Select item 109850022.

TRIB3 promotes the progression of renal cell carcinoma by upregulating the lipid droplet-associated protein PLIN2

Jun Li, Qian Zhang, Yupeng Guan, Dingzhun Liao, Huikun Chen, Haiyun Xiong, Yiyu Sheng, Xianju Chen, Jun Pang

Cell Death Dis. 2024 Apr; 15(4): 240. Published online 2024 Apr 1. doi: 10.1038/s41419-024-06627-4

PMCID:: PMC10985002

Abstract Article PDF–8.0M

Select item 109077163.

TRIB3 promotes malignancy of head and neck squamous cell carcinoma via inhibiting ferroptosis

Li Chen, Wanzun Lin, Haojiong Zhang, Shikai Geng, Ziyu Le, Fangzhu Wan, Qingting Huang, Huaiyuan Chen, Xingyu Liu, Jiade J. Lu, Lin Kong

Cell Death Dis. 2024 Mar; 15(3): 178. Published online 2024 Mar 1. doi: 10.1038/s41419-024-06472-5

PMCID:: PMC10907716

Abstract Article PDF–6.6M

Select item 108596914.

Integration of dietary nutrition and TRIB3 action into diabetes mellitus

Guangping Lu, Jiahao Li, Ting Gao, Qingbo Liu, Ou Chen, Xiaohui Zhang, Mengjie Xiao, Yuanfang Guo, Jie Wang, Yufeng Tang, Junlian Gu

Nutr Rev. 2024 Mar; 82(3): 361–373. Published online 2023 May 24. doi: 10.1093/nutrit/nuad056

PMCID:: PMC10859691

Abstract Article PDF–709K

Select item 107918105.

TRIB3, as a robust prognostic biomarker for HNSC, is associated with poor immune infiltration and cancer cell immune evasion

Huadong Wu, Zhenzhen Fu, Hong Li, Feifei Fang, Bin He, Yujie Ye, Heyong Wu, Dong Xu, Haoran Zheng, Qiang Zhang

Front Immunol. 2023; 14: 1290839. Published online 2024 Jan 3. doi: 10.3389/fimmu.2023.1290839

PMCID:: PMC10791810

Abstract Article PDF–7.9M

Select item 107134116.

A prognostic risk model for programmed cell death and revealing TRIB3 as a promising apoptosis suppressor in renal cell carcinoma

Qingfeng Fu, Bocun Yi, Qiang Su, Yue Huang, Lin Wang, Zhihong Zhang

Aging (Albany NY) 2023 Nov 30; 15(22): 13213–13238. Published online 2023 Nov 22. doi: 10.18632/aging.205237

PMCID:: PMC10713411

Abstract Article PDF–4.0M

Select item 106145127.

Transcription Factor Sox9 Exacerbates Kidney Injury through Inhibition of MicroRNA-96-5p and Activation of the Trib3/IL-6 Axis

Xiao Wang, Guang Chen, Yongqiang Du, Jiajia Yang, Wei Wang

Kidney Blood Press Res. 2023 Jan-Dec; 48(1): 611–627. Published online 2023 Sep 16. doi: 10.1159/000533544

PMCID:: PMC10614512

Abstract Article

Select item 101518268.

Upregulation of Tribbles decreases body weight and increases sleep duration

Rebeka Popovic, Yizhou Yu, Nuno Santos Leal, Giorgio Fedele, Samantha H. Y. Loh, L. Miguel Martins

Dis Model Mech. 2023 Apr 1; 16(4): dmm049942. Published online 2023 Apr 21. doi: 10.1242/dmm.049942

PMCID:: PMC10151826

Abstract Article

Select item 97789459.

TRIB3 Mediates Fibroblast Activation and Fibrosis though Interaction with ATF4 in IPF

Lan Wang, Wenyu Zhao, Cong Xia, Zhongzheng Li, Weiming Zhao, Kai Xu, Ningdan Wang, Hui Lian, Ivan O. Rosas, Guoying Yu

Int J Mol Sci. 2022 Dec; 23(24): 15705. Published online 2022 Dec 11. doi: 10.3390/ijms232415705

PMCID:: PMC9778945

Abstract Article PDF–4.1M

Select item 950393410.

TRIB3 Modulates PPARγ-Mediated Growth Inhibition by Interfering with the MLL Complex in Breast Cancer Cells

Miguel Hernández-Quiles, Rosalie Baak, Alba Orea-Soufi, Anouska Borgman, Suzanne den Haan, Paula Sobrevals Alcaraz, Aldo Jongejan, Robert van Es, Guillermo Velasco, Harmjan Vos, Eric Kalkhoven

Int J Mol Sci. 2022 Sep; 23(18): 10535. Published online 2022 Sep 11. doi: 10.3390/ijms231810535

PMCID:: PMC9503934

Abstract Article PDF–2.1M

Select item 932055111.

High TRB3 expression induces chondrocyte autophagy and senescence in osteoarthritis cartilage

Yanqing Gu, Ren Yan, Yang Wang, Yiwen Zeng, Qingqiang Yao

Aging (Albany NY) 2022 Jul 15; 14(13): 5366–5375. Published online 2022 Jul 1. doi: 10.18632/aging.204066

PMCID:: PMC9320551

Abstract Article PDF–920K

Select item 927588212.

Increased expression of tribbles homolog 3 predicts poor prognosis and correlates with tumor immunity in clear cell renal cell carcinoma: a bioinformatics study

Xin-Qiang Wu, Xi Tian, Fu-Jiang Xu, Yue Wang, Wen-Hao Xu, Jia-Qi Su, Yuan-Yuan Qu, Jian-Yuan Zhao, Hai-Liang Zhang, Ding-Wei Ye

Bioengineered. 2022; 13(5): 14000–14012. Published online 2022 Jun 20. doi: 10.1080/21655979.2022.2086380

PMCID:: PMC9275882

Abstract Article PDF–11M

Select item 926261413.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 916373914.

TRAF6 Suppresses the Development of Pulmonary Fibrosis by Attenuating the Activation of Fibroblasts

Jiali Min, Qiao Li, Suosi Liu, Qianrong Wang, Min Yin, Yan Zhang, Jun Yan, Bing Cui, Shanshan Liu

Front Pharmacol. 2022; 13: 911945. Published online 2022 May 20. doi: 10.3389/fphar.2022.911945

PMCID:: PMC9163739

Abstract Article PDF–4.4M

Select item 904483415.

Deletion of TRIB3 disrupts the tumor progression induced by integrin αvβ3 in lung cancer

Wen Zhou, Junjun Ma, Lifeng Meng, Dabei Liu, Jun Chen

BMC Cancer. 2022; 22: 459. Published online 2022 Apr 26. doi: 10.1186/s12885-022-09593-2

PMCID:: PMC9044834

Abstract Article PDF–4.4M

Select item 854689216.

TRIB3‒GSK-3β interaction promotes lung fibrosis and serves as a potential therapeutic target

Shanshan Liu, Xiaoxi Lv, Xupeng Wei, Chang Liu, Qiao Li, Jiali Min, Fang Hua, Xiaowei Zhang, Ke Li, Pingping Li, Yang Xiao, Zhuowei Hu, Bing Cui

Acta Pharm Sin B. 2021 Oct; 11(10): 3105–3119. Published online 2021 Jul 7. doi: 10.1016/j.apsb.2021.06.017

PMCID:: PMC8546892

Abstract Article PDF–6.6M

Select item 848619917.

Tumor‐associated macrophage‐derived transforming growth factor‐β promotes colorectal cancer progression through HIF1‐TRIB3 signaling

Changfu Liu, Weihao Zhang, Junfeng Wang, Tongguo Si, Wenge Xing

Cancer Sci. 2021 Oct; 112(10): 4198–4207. Published online 2021 Aug 23. doi: 10.1111/cas.15101

PMCID:: PMC8486199

Abstract Article PDF–1.5M

Select item 842810918.

TRIB3 regulates FSHR expression in human granulosa cells under high levels of free fatty acids

Nan Wang, Chenchen Si, Lan Xia, Xian Wu, Sheng Zhao, Huihui Xu, Zhide Ding, Zhihong Niu

Reprod Biol Endocrinol. 2021; 19: 139. Published online 2021 Sep 9. doi: 10.1186/s12958-021-00823-z

PMCID:: PMC8428109

Abstract Article PDF–3.7M

Select item 820345319.

Stabilization of fatty acid synthesis enzyme acetyl-CoA carboxylase 1 suppresses acute myeloid leukemia development

Hidenori Ito, Ikuko Nakamae, Jun-ya Kato, Noriko Yoneda-Kato

J Clin Invest. 2021 Jun 15; 131(12): e141529. Published online 2021 Jun 15. doi: 10.1172/JCI141529

PMCID:: PMC8203453

Abstract Article PDF–8.8M

Select item 816503020.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

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PMC Links for GEO Profiles (Select 73309631) (81)
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Conserved Domain Links for Protein (Select 586728291) (1)
Conserved Domains
PREDICTED: Mus musculus ring finger protein 180 (Rnf180), transcript variant X17...
PREDICTED: Mus musculus ring finger protein 180 (Rnf180), transcript variant X17, mRNA
gi|1907094541|ref|XM_036158174.1|

Nucleotide
E3 ubiquitin-protein ligase RNF180 isoform X9 [Mus musculus]
E3 ubiquitin-protein ligase RNF180 isoform X9 [Mus musculus]
gi|1907094536|ref|XP_036014064.1|

Protein

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