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Select item 111481841.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 105759592.

Mouse Slfn8 and Slfn9 genes complement human cells lacking SLFN11 during the replication stress response

Erin Alvi, Ayako L. Mochizuki, Yoko Katsuki, Minori Ogawa, Fei Qi, Yusuke Okamoto, Minoru Takata, Anfeng Mu

Commun Biol. 2023; 6: 1038. Published online 2023 Oct 13. doi: 10.1038/s42003-023-05406-9

PMCID:: PMC10575959

Abstract Article PDF–3.6M

Select item 96484173.

SLFN11 Negatively Regulates Noncanonical NFκB Signaling to Promote Glioblastoma Progression

Mariafausta Fischietti, Frank Eckerdt, Ricardo E. Perez, Jamie N. Guillen Magaña, Candice Mazewski, Sang Ho, Christopher Gonzalez, Lukas D. Streich, Elspeth M. Beauchamp, Amy B. Heimberger, Aneta H. Baran, Feng Yue, C. David James, Leonidas C. Platanias

Cancer Res Commun. 2022 Sep; 2(9): 966–978. Published online 2022 Sep 13. doi: 10.1158/2767-9764.CRC-22-0192

PMCID:: PMC9648417

Abstract Article PDF–7.7M

Select item 94826584.

Mechanistic understanding of human SLFN11

Felix J. Metzner, Simon J. Wenzl, Michael Kugler, Stefan Krebs, Karl-Peter Hopfner, Katja Lammens

Nat Commun. 2022; 13: 5464. Published online 2022 Sep 17. doi: 10.1038/s41467-022-33123-0

PMCID:: PMC9482658

Abstract Article PDF–2.2M

Select item 94819335.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 93461196.

Dynamic expression of Schlafen 11 (SLFN11) in circulating tumour cells as a liquid biomarker in small cell lung cancer

Bingnan Zhang, C. Allison Stewart, Qi Wang, Robert J. Cardnell, Pedro Rocha, Junya Fujimoto, Luisa M. Solis Soto, Runsheng Wang, Veronica Novegil, Peter Ansell, Lei He, Luisa Fernandez, Adam Jendrisak, Cole Gilbertson, Joseph D. Schonhoft, Jiyun Byun, Joshua Jones, Amanda K. L. Anderson, Ana Aparicio, Hai Tran, Marcelo V. Negrao, Jianjun Zhang, Wei-lien Wang, Ignacio I. Wistuba, Jing Wang, Rick Wenstrup, Lauren A. Byers, Carl M. Gay

Br J Cancer. 2022 Aug 1; 127(3): 569–576. Published online 2022 Apr 19. doi: 10.1038/s41416-022-01811-9

PMCID:: PMC9346119

Abstract Article PDF–2.5M

Select item 93436107.

FK228 potentiates topotecan activity against small cell lung cancer cells via induction of SLFN11

Yan-ping Yin, Li-ying Ma, Guo-zhen Cao, Jing-han Hua, Xiao-tong Lv, Wen-chu Lin

Acta Pharmacol Sin. 2022 Aug; 43(8): 2119–2127. Published online 2021 Dec 10. doi: 10.1038/s41401-021-00817-y

PMCID:: PMC9343610

Abstract Article PDF–3.0M

Select item 92265108.

ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia

Linjiang Lao, Isabelle Bourdeau, Lucia Gagliardi, Xiao He, Wei Shi, Bingbing Hao, Minjia Tan, Yan Hu, Junzheng Peng, Benoit Coulombe, David J Torpy, Hamish S Scott, Andre Lacroix, Hongyu Luo, Jiangping Wu

Nucleic Acids Res. 2022 Jun 24; 50(11): 6343–6367. Published online 2022 Jun 10. doi: 10.1093/nar/gkac483

PMCID:: PMC9226510

Abstract Article PDF–3.7M

Select item 91755119.

Immunohistochemical analysis of SLFN11 expression uncovers potential non-responders to DNA-damaging agents overlooked by tissue RNA-seq

Tsuyoshi Takashima, Naoya Sakamoto, Junko Murai, Daiki Taniyama, Ririno Honma, Shoichi Ukai, Ryota Maruyama, Kazuya Kuraoka, Vinodh N. Rajapakse, Yves Pommier, Wataru Yasui

Virchows Arch. Author manuscript; available in PMC 2022 Jun 8.

Published in final edited form as: Virchows Arch. 2021 Mar; 478(3): 569–579. Published online 2020 May 30. doi: 10.1007/s00428-020-02840-6

PMCID:: PMC9175511

Abstract Article PDF–2.8M

Select item 917141110.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 910523511.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 905883612.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Abstract Article PDF–2.9M

Select item 903609213.

Tumor suppressor BAP1 nuclear import is governed by transportin-1

Tzu-Jing Yang, Tian-Neng Li, Rih-Sheng Huang, Max Yu-Chen Pan, Shu-Yu Lin, Steven Lin, Kuen-Phon Wu, Lily Hui-Ching Wang, Shang-Te Danny Hsu

J Cell Biol. 2022 Jun 6; 221(6): e202201094. Published online 2022 Apr 21. doi: 10.1083/jcb.202201094

PMCID:: PMC9036092

Abstract Article PDF–4.0M

Select item 889702214.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 889438015.

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing

Alexandra Bergfort, Marco Preußner, Benno Kuropka, İbrahim Avşar Ilik, Tarek Hilal, Gert Weber, Christian Freund, Tuğçe Aktaş, Florian Heyd, Markus C. Wahl

Nat Commun. 2022; 13: 1132. Published online 2022 Mar 3. doi: 10.1038/s41467-022-28754-2

PMCID:: PMC8894380

Abstract Article PDF–5.6M

Select item 886447216.

Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network

Rebecca Elizabeth Kattan, Han Han, Gayoung Seo, Bing Yang, Yongqi Lin, Max Dotson, Stephanie Pham, Yahya Menely, Wenqi Wang

Mol Cell Proteomics. 2022 Feb; 21(2): 100195. Published online 2022 Jan 8. doi: 10.1016/j.mcpro.2022.100195

PMCID:: PMC8864472

Abstract Article PDF–3.6M

Select item 883297017.

Human cytomegalovirus protein RL1 degrades the antiviral factor SLFN11 via recruitment of the CRL4 E3 ubiquitin ligase complex

Katie Nightingale, Martin Potts, Leah M. Hunter, Ceri A. Fielding, Cassie M. Zerbe, Alice Fletcher-Etherington, Luis Nobre, Eddie C. Y. Wang, Blair L. Strang, Jack W. Houghton, Robin Antrobus, Nicolas M. Suarez, Jenna Nichols, Andrew J. Davison, Richard J. Stanton, Michael P. Weekes

Proc Natl Acad Sci U S A. 2022 Feb 8; 119(6): e2108173119. Published online 2022 Feb 1. doi: 10.1073/pnas.2108173119

PMCID:: PMC8832970

Abstract Article PDF–1.2M

Select item 866274018.

BRCAness, SLFN11, and RB1 loss predict response to topoisomerase I inhibitors in triple-negative breast cancers

Florence Coussy, Rania El-Botty, Sophie Château-Joubert, Ahmed Dahmani, Elodie Montaudon, Sophie Leboucher, Ludivine Morisset, Pierre Painsec, Laura Sourd, Léa Huguet, Fariba Nemati, Jean-Luc Servely, Thibaut Larcher, Sophie Vacher, Adrien Briaux, Cécile Reyes, Philippe La Rosa, Georges Lucotte, Tatiana Popova, Pierre Foidart, Nor Eddine Sounni, Agnès Noel, Didier Decaudin, Laetitia Fuhrmann, Anne Salomon, Fabien Reyal, Christopher Mueller, Petra Ter Brugge, Jos Jonkers, Marie-France Poupon, Marc-Henri Stern, Ivan Bièche, Yves Pommier, Elisabetta Marangoni

Sci Transl Med. Author manuscript; available in PMC 2021 Dec 10.

Published in final edited form as: Sci Transl Med. 2020 Feb 19; 12(531): eaax2625. doi: 10.1126/scitranslmed.aax2625

PMCID:: PMC8662740

Abstract Article PDF–1.7M

Select item 865181119.

Retrospective analysis of Schlafen11 (SLFN11) to predict the outcomes to therapies affecting the DNA damage response

Sophie E. Willis, Claudia Winkler, Martine P. Roudier, Tarrion Baird, Paola Marco-Casanova, Emma V. Jones, Philip Rowe, Jaime Rodriguez-Canales, Helen K. Angell, Felicia S. L. Ng, Paul M. Waring, Darren Hodgson, Jonathan A. Ledermann, Johanne I. Weberpals, Emma Dean, Elizabeth A. Harrington, J. Carl Barrett, Andrew J. Pierce, Elisabetta Leo, Gemma N. Jones

Br J Cancer. 2021 Dec 7; 125(12): 1666–1676. Published online 2021 Oct 18. doi: 10.1038/s41416-021-01560-1

PMCID:: PMC8651811

Abstract Article PDF–10M

Select item 864283120.

SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response

Syed Nabeel-Shah, Hyunmin Lee, Nujhat Ahmed, Giovanni L. Burke, Shaghayegh Farhangmehr, Kanwal Ashraf, Shuye Pu, Ulrich Braunschweig, Guoqing Zhong, Hong Wei, Hua Tang, Jianyi Yang, Edyta Marcon, Benjamin J. Blencowe, Zhaolei Zhang, Jack F. Greenblatt

iScience. 2022 Jan 21; 25(1): 103562. Published online 2021 Dec 4. doi: 10.1016/j.isci.2021.103562

PMCID:: PMC8642831

Abstract Article PDF–5.2M

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Tylospora fibrillosa isolate 428 18S ribosomal RNA gene, partial sequence; inter...
Tylospora fibrillosa isolate 428 18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 28S ribosomal RNA gene, partial sequence
gi|953872549|gb|KP783485.1|

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