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Select item 97559991.

Whole-exome sequencing identifies FOXL2, FOXA2 and FOXA3 as candidate genes for monogenic congenital anomalies of the kidneys and urinary tract

Bixia Zheng, Steve Seltzsam, Chunyan Wang, Luca Schierbaum, Sophia Schneider, Chen-Han Wilfred Wu, Rufeng Dai, Dervla M Connaughton, Makiko Nakayama, Nina Mann, Natasa Stajic, Shrikant Mane, Stuart B Bauer, Velibor Tasic, Hyun Joo Nam, Shirlee Shril, Friedhelm Hildebrandt

Nephrol Dial Transplant. 2022 Oct; 37(10): 1833–1843. Published online 2021 Sep 2. doi: 10.1093/ndt/gfab253

PMCID:: PMC9755999

Abstract Article PDF–1.8M

Select item 91391292.

FOXA3 Polymorphisms Are Associated with Metabolic Parameters in Individuals with Subclinical Atherosclerosis and Healthy Controls—The GEA Mexican Study

Gilberto Vargas-Alarcón, José Manuel Fragoso, Julian Ramírez-Bello, Rosalinda Posadas-Sánchez

Biomolecules. 2022 May; 12(5): 601. Published online 2022 Apr 19. doi: 10.3390/biom12050601

PMCID:: PMC9139129

Abstract Article PDF–511K

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80090484.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 79579755.

Transcription factor FOXA3 promotes the development of Hepatoblastoma via regulating HNF1A, AFP, and ZFHX3 expression

Xiaoyun Zhan, Alan Zhao

J Clin Lab Anal. 2021 Mar; 35(3): e23686. Published online 2020 Dec 24. doi: 10.1002/jcla.23686

PMCID:: PMC7957975

Abstract Article PDF–683K

Select item 77627546.

m6A RNA methylation-mediated HNF3γ reduction renders hepatocellular carcinoma dedifferentiation and sorafenib resistance

Tengfei Zhou, Shichao Li, Daimin Xiang, Junyu Liu, Wen Sun, Xiuliang Cui, Beifang Ning, Xiao Li, Zhuo Cheng, Weiqi Jiang, Cheng Zhang, Xijun Liang, Liang Li, Xin Cheng, Liu Hui, Hongyang Wang, Jin Ding

Signal Transduct Target Ther. 2020; 5: 296. Published online 2020 Dec 26. doi: 10.1038/s41392-020-00299-0

PMCID:: PMC7762754

Abstract Article PDF–6.6M

Select item 70842567.

Opposing Roles of FoxA1 and FoxA3 in Intrahepatic Cholangiocarcinoma Progression

Raynoo Thanan, Waleeporn Kaewlert, Chadamas Sakonsinsiri, Timpika Chaiprasert, Napat Armartmuntree, Duangkamon Muengsaen, Anchalee Techasen, Poramate Klanrit, Worachart Lert-itthiporn, Somchai Pinlaor, Chawalit Pairojkul

Int J Mol Sci. 2020 Mar; 21(5): 1796. Published online 2020 Mar 5. doi: 10.3390/ijms21051796

PMCID:: PMC7084256

Abstract Article PDF–2.2M

Select item 66566278.

Hepatic forkhead box protein A3 regulates ApoA-I expression, cholesterol efflux and atherogenesis

Yuanyuan Li, Yanyong Xu, Kavita Jadhav, Yingdong Zhu, Liya Yin, Yanqiao Zhang

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2020 Aug 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2019 Aug; 39(8): 1574–1587. Published online 2019 Jul 11. doi: 10.1161/ATVBAHA.119.312610

PMCID:: PMC6656627

Abstract Article PDF–2.0M

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 446276710.

Analysis of variants and mutations in the human winged helix FOXA3 gene and associations with metabolic traits

D C Adler-Wailes, A T Alberobello, X Ma, L Hugendubler, E A Stern, Z Mou, J C Han, P W Kim, A E Sumner, J A Yanovski, E Mueller

Int J Obes (Lond) 2015 Jun; 39(6): 888–892. Prepublished online 2015 Feb 12. Published online 2015 Mar 3. doi: 10.1038/ijo.2015.17

PMCID:: PMC4462767

Abstract Article PDF–433K

Select item 433215011.

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

Xu Li, Wenqi Wang, Jiadong Wang, Anna Malovannaya, Yuanxin Xi, Wei Li, Rudy Guerra, David H Hawke, Jun Qin, Junjie Chen

Mol Syst Biol. 2015 Jan; 11(1): 775. Published online 2015 Jan 21. doi: 10.15252/msb.20145504

PMCID:: PMC4332150

Abstract Article PDF–2.8M

Select item 397773112.

Foxa3 Induces Goblet Cell Metaplasia and Inhibits Innate Antiviral Immunity

Gang Chen, Thomas R. Korfhagen, Christopher L. Karp, Soren Impey, Yan Xu, Scott H. Randell, Joseph Kitzmiller, Yutaka Maeda, Hans Michael Haitchi, Anusha Sridharan, Albert P. Senft, Jeffrey A. Whitsett

Am J Respir Crit Care Med. 2014 Feb 1; 189(3): 301–313. Published online 2014 Feb 1. doi: 10.1164/rccm.201306-1181OC

PMCID:: PMC3977731

Abstract Article PDF–3.2M

Select item 375385613.

The Winged Helix Transcription Factor Foxa3 Regulates Adipocyte Differentiation and Depot-Selective Fat Tissue Expansion

Lingyan Xu, Valentine Panel, Xinran Ma, Chen Du, Lynne Hugendubler, Oksana Gavrilova, Alice Liu, Tracey McLaughlin, Klaus H. Kaestner, Elisabetta Mueller

Mol Cell Biol. 2013 Sep; 33(17): 3392–3399. doi: 10.1128/MCB.00244-13

PMCID:: PMC3753856

Abstract Article PDF–2.1M

Select item 326170814.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67

Correction in:: Mol Syst Biol. 2017 Dec; 13(12): 965.

PMCID:: PMC3261708

Abstract Article PDF–2.0M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 309132216.

Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq

Mehdi Motallebipour, Adam Ameur, Madhu Sudhan Reddy Bysani, Kalicharan Patra, Ola Wallerman, Jonathan Mangion, Melissa A Barker, Kevin J McKernan, Jan Komorowski, Claes Wadelius

Genome Biol. 2009; 10(11): R129. Published online 2009 Nov 17. doi: 10.1186/gb-2009-10-11-r129