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Select item 111627931.

Human AAA+ ATPase FIGNL1 suppresses RAD51-mediated ultra-fine bridge formation

Kenichiro Matsuzaki, Akira Shinohara, Miki Shinohara

Nucleic Acids Res. 2024 Jun 10; 52(10): 5774–5791. Published online 2024 Apr 10. doi: 10.1093/nar/gkae263

PMCID:: PMC11162793

Abstract Article PDF–1.7M

Select item 111598402.

Comprehensive analysis of DNA repair gene polymorphisms and survival in patients with early stage non‐small‐cell lung cancer

Min Kim, Hyo‐Gyoung Kang, Shin Yup Lee, Hyung Cheol Lee, Eung Bae Lee, Yi Young Choi, Won Kee Lee, Sukki Cho, Guang Jin, Hyo‐Sung Jheon, Ji Woong Son, Myung‐Hoon Lee, Deuk Kju Jung, Seung Ick Cha, Chang Ho Kim, Young Mo Kang, Sin Kam, Tae Hoon Jung, Sanghoon Jheon, Jae Yong Park

Cancer Sci. 2010 Nov; 101(11): 2436–2442. Published online 2010 Jul 31. doi: 10.1111/j.1349-7006.2010.01699.x

PMCID:: PMC11159840

Abstract Article PDF–209K

Select item 110113763.

Human Rad51 Protein Requires Higher Concentrations of Calcium Ions for D-Loop Formation than for Oligonucleotide Strand Exchange

Axelle Renodon-Corniere, Tsutomu Mikawa, Naoyuki Kuwabara, Kentaro Ito, Dmitri Levitsky, Hiroshi Iwasaki, Masayuki Takahashi

Int J Mol Sci. 2024 Apr; 25(7): 3633. Published online 2024 Mar 24. doi: 10.3390/ijms25073633

PMCID:: PMC11011376

Abstract Article PDF–2.1M

Select item 109909314.

Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site

Takuro Shioi, Suguru Hatazawa, Eriko Oya, Noriko Hosoya, Wataru Kobayashi, Mitsuo Ogasawara, Takehiko Kobayashi, Yoshimasa Takizawa, Hitoshi Kurumizaka

Nature. 2024; 628(8006): 212–220. Published online 2024 Mar 20. doi: 10.1038/s41586-024-07196-4

PMCID:: PMC10990931

Abstract Article PDF–20M

Select item 109544805.

Trans-complementation by the RecB nuclease domain of RecBCD enzyme reveals new insight into RecA loading upon χ recognition

Theetha L Pavankumar, C Jason Wong, Yun Ka Wong, Maria Spies, Stephen C Kowalczykowski

Nucleic Acids Res. 2024 Mar 21; 52(5): 2578–2589. Published online 2024 Jan 23. doi: 10.1093/nar/gkae007

PMCID:: PMC10954480

Abstract Article PDF–1.4M

Select item 109429846.

RAD51 restricts DNA over-replication from re-activated origins

Sergio Muñoz, Elena Blanco-Romero, Daniel González-Acosta, Sara Rodriguez-Acebes, Diego Megías, Massimo Lopes, Juan Méndez

EMBO J. 2024 Mar; 43(6): 1043–1064. Published online 2024 Feb 15. doi: 10.1038/s44318-024-00038-z

PMCID:: PMC10942984

Abstract Article PDF–5.7M

Select item 109238317.

GRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancer

Zu Ye, Shengfeng Xu, Yin Shi, Xueqian Cheng, Yuan Zhang, Sunetra Roy, Sarita Namjoshi, Michael A. Longo, Todd M. Link, Katharina Schlacher, Guang Peng, Dihua Yu, Bin Wang, John A. Tainer, Zamal Ahmed

Nat Commun. 2024; 15: 2132. Published online 2024 Mar 8. doi: 10.1038/s41467-024-46283-y

PMCID:: PMC10923831

Abstract Article PDF–3.7M

Select item 108650738.

Association between polymorphisms of the DNA repair genes RAD51 and OGG1 and risk of cardiovascular disease

Amar Alomair, Abdullah Alamri, Jilani Shaik, Salman Aljafari, Mohammed Ba Abdullah, Mohammad Alanazi

Mol Med Rep. 2024 Mar; 29(3): 53. Published online 2024 Feb 7. doi: 10.3892/mmr.2024.13177

PMCID:: PMC10865073

Abstract Article PDF–1.5M

Select item 108251459.

FLIP(C1orf112)-FIGNL1 complex regulates RAD51 chromatin association to promote viability after replication stress

Jessica D. Tischler, Hiroshi Tsuchida, Rosevalentine Bosire, Tommy T. Oda, Ana Park, Richard O. Adeyemi

Nat Commun. 2024; 15: 866. Published online 2024 Jan 29. doi: 10.1038/s41467-024-45139-9

PMCID:: PMC10825145

Abstract Article PDF–3.0M

Select item 1073466710.

Differential impact of cytoplasmic vs. nuclear RAD51 expression on breast cancer progression and patient prognosis

Yen-Yun Wang, Kuang-Hung Cheng, Amos C. Hung, Steven Lo, Pang-Yu Chen, Yi-Chia Wu, Ming-Feng Hou, Shyng-Shiou F. Yuan

Int J Oncol. 2024 Feb; 64(2): 12. Published online 2023 Dec 7. doi: 10.3892/ijo.2023.5600

PMCID:: PMC10734667

Abstract Article PDF–6.6M

Select item 1073446311.

SARS-CoV-2 exploits cellular RAD51 to promote viral propagation: implication of RAD51 inhibitor as a potential drug candidate against COVID-19

Thuy X. Pham, Trang T. X. Huynh, Jiwon Choi, Jae-Bong Lee, Seok-Chan Park, Bumseok Kim, Yun-Sook Lim, Soon B. Hwang

J Virol. 2023 Dec; 97(12): e01737-23. Published online 2023 Dec 5. doi: 10.1128/jvi.01737-23

PMCID:: PMC10734463

Abstract Article PDF–7.7M

Select item 1071658112.

Fanconi anemia-associated mutation in RAD51 compromises the coordinated action of DNA-binding and ATPase activities

Sijia Liu, Akira Shinohara, Asako Furukohri

J Biol Chem. 2023 Dec; 299(12): 105424. Published online 2023 Nov 2. doi: 10.1016/j.jbc.2023.105424

PMCID:: PMC10716581

Abstract Article PDF–2.7M

Select item 1071343613.

Human RAD52 stimulates the RAD51-mediated homology search

Ali Akbar Muhammad, Clara Basto, Thibaut Peterlini, Josée Guirouilh-Barbat, Melissa Thomas, Xavier Veaute, Didier Busso, Bernard Lopez, Gerard Mazon, Eric Le Cam, Jean-Yves Masson, Pauline Dupaigne

Life Sci Alliance. 2024 Mar; 7(3): e202201751. Published online 2023 Dec 11. doi: 10.26508/lsa.202201751

PMCID:: PMC10713436

Abstract Article PDF–3.5M

Select item 1062257714.

Structural basis for stabilisation of the RAD51 nucleoprotein filament by BRCA2

Robert Appleby, Luay Joudeh, Katie Cobbett, Luca Pellegrini

Nat Commun. 2023; 14: 7003. Published online 2023 Nov 2. doi: 10.1038/s41467-023-42830-1

PMCID:: PMC10622577

Abstract Article PDF–3.3M

Select item 1061173315.

FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination

Masaru Ito, Asako Furukohri, Kenichiro Matsuzaki, Yurika Fujita, Atsushi Toyoda, Akira Shinohara

Nat Commun. 2023; 14: 6857. Published online 2023 Oct 27. doi: 10.1038/s41467-023-42576-w

PMCID:: PMC10611733

Abstract Article PDF–5.5M

Select item 1051663716.

FANCD2 and RAD51 recombinase directly inhibit DNA2 nuclease at stalled replication forks and FANCD2 acts as a novel RAD51 mediator in strand exchange to promote genome stability

Wenpeng Liu, Piotr Polaczek, Ivan Roubal, Yuan Meng, Won-chae Choe, Marie-Christine Caron, Carl A Sedgeman, Yu Xi, Changwei Liu, Qiong Wu, Li Zheng, Jean-Yves Masson, Binghui Shen, Judith L Campbell

Nucleic Acids Res. 2023 Sep 22; 51(17): 9144–9165. Published online 2023 Aug 1. doi: 10.1093/nar/gkad624

PMCID:: PMC10516637

Abstract Article PDF–2.0M

Select item 1043483817.

DNA Strand Exchange to Monitor Human RAD51-Mediated Strand Invasion and Pairing

Sudipta Lahiri, Ryan B. Jensen

Methods Mol Biol. Author manuscript; available in PMC 2023 Aug 17.

Published in final edited form as: Methods Mol Biol. 2021; 2153: 101–113. doi: 10.1007/978-1-0716-0644-5_8

PMCID:: PMC10434838

Abstract Article PDF–1.2M

Select item 1032330418.

RAD51/geminin/γH2AX immunohistochemical expression predicts platinum-based chemotherapy response in ovarian high-grade serous carcinoma

Kyeongmin Kim, Se Hoon Kim, Jung-Yun Lee, Yoo-Na Kim, Seung-Tae Lee, Eunhyang Park

J Gynecol Oncol. 2023 Jul; 34(4): e45. Published online 2023 Feb 3. doi: 10.3802/jgo.2023.34.e45

PMCID:: PMC10323304

Abstract Article PDF–6.2M

Select item 1029450919.

LCK facilitates DNA damage repair by stabilizing RAD51 and BRCA1 in the nucleus of chemoresistant ovarian cancer

Goutam Dey, Rashmi Bharti, Chad Braley, Ravi Alluri, Emily Esakov, Katie Crean-Tate, Keith McCrae, Amy Joehlin-Price, Peter G. Rose, Justin Lathia, Zihua Gong, Ofer Reizes

J Ovarian Res. 2023; 16: 122. Published online 2023 Jun 27. doi: 10.1186/s13048-023-01194-2

PMCID:: PMC10294509

Abstract Article PDF–8.5M

Select item 1021305020.

Bre1/RNF20 promotes Rad51-mediated strand exchange and antagonizes the Srs2/FBH1 helicases

Guangxue Liu, Jimin Li, Boxue He, Jiaqi Yan, Jingyu Zhao, Xuejie Wang, Xiaocong Zhao, Jingyan Xu, Yeyao Wu, Simin Zhang, Xiaoli Gan, Chun Zhou, Xiangpan Li, Xinghua Zhang, Xuefeng Chen

Nat Commun. 2023; 14: 3024. Published online 2023 May 25. doi: 10.1038/s41467-023-38617-z