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Select item 111618291.

Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart

Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Marc‐Phillip Hitz, Gregor Dombrowsky, Friederike Cuello, J. David Brook, Siobhan Loughna

J Anat. 2024 Jul; 245(1): 70–83. Published online 2024 Feb 28. doi: 10.1111/joa.14033

PMCID:: PMC11161829

Abstract Article PDF–5.8M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 101120083.

Protein kinase D3 promotes neutrophil migration during viral infection

Janelle M Veazey, Gordon S Wong, Sophia I Eliseeva, Timothy R Smyth, Timothy J Chapman, Kihong Lim, Minsoo Kim, Steve N Georas

Immunol Cell Biol. Author manuscript; available in PMC 2023 Apr 18.

Published in final edited form as: Immunol Cell Biol. 2023 Feb; 101(2): 130–141. Published online 2022 Nov 24. doi: 10.1111/imcb.12603

PMCID:: PMC10112008

Abstract Article PDF–1.4M

Select item 97138234.

T cell-intrinsic protein kinase D3 is dispensable for the cells’ activation

Jiří Koutník, Michael Leitges, Kerstin Siegmund

Front Immunol. 2022; 13: 1049033. Published online 2022 Nov 17. doi: 10.3389/fimmu.2022.1049033

PMCID:: PMC9713823

Abstract Article PDF–6.1M

Select item 93387855.

Deletion of Protein Kinase D3 Promotes Liver Fibrosis in Mice

Shuya Zhang, Huan Liu, Meimei Yin, Xiuying Pei, Angelika Hausser, Eri Ishikawa, Sho Yamasaki, Zheng Gen Jin

Hepatology. Author manuscript; available in PMC 2022 Jul 30.

Published in final edited form as: Hepatology. 2020 Nov; 72(5): 1717–1734. Published online 2020 Sep 28. doi: 10.1002/hep.31176

PMCID:: PMC9338785

Abstract Article PDF–3.3M

Select item 90351016.

Histone Deacetylase 5 is a Phosphorylation Substrate of Protein Kinase D in Osteoclasts

Carina Mello Guimaraes Meyers, Samuel D Burciaga, Bora Faulkner, Parandis Kazemi, Jacob M Cohn, Kim C Mansky, Eric D Jensen

Bone. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: Bone. 2022 Jun; 159: 116393. Published online 2022 Mar 19. doi: 10.1016/j.bone.2022.116393

PMCID:: PMC9035101

Abstract Article PDF–2.8M

Select item 90200817.

Addressing the role of PKD3 in the T cell compartment with knockout mice

Jiří Koutník, Verena Neururer, Thomas Gruber, Sebastian Peer, Natascha Hermann-Kleiter, William J. Olson, Verena Labi, Michael Leitges, Gottfried Baier, Kerstin Siegmund

Cell Commun Signal. 2022; 20: 54. Published online 2022 Apr 19. doi: 10.1186/s12964-022-00864-w

PMCID:: PMC9020081

Abstract Article PDF–2.7M

Select item 83216628.

A phosphoproteomic approach reveals that PKD3 controls PKA-mediated glucose and tyrosine metabolism

Angel Loza-Valdes, Alexander E Mayer, Toufic Kassouf, Jonathan Trujillo-Viera, Werner Schmitz, Filip Dziaczkowski, Michael Leitges, Andreas Schlosser, Grzegorz Sumara

Life Sci Alliance. 2021 Aug; 4(8): e202000863. Published online 2021 Jun 18. doi: 10.26508/lsa.202000863

PMCID:: PMC8321662

Abstract Article PDF–2.3M

Select item 83132399.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 781017010.

Pancreas-specific deletion of protein kinase D attenuates inflammation, necrosis, and severity of acute pancreatitis

Jingzhen Yuan, Chintan Chheda, Honit Piplani, Meng Geng, Grace Tan, Reetu Thakur, Stephen J. Pandol

Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2021 Jan 1; 1867(1): 165987. Published online 2020 Oct 9. doi: 10.1016/j.bbadis.2020.165987

PMCID:: PMC7810170

Abstract Article PDF–4.2M

Select item 776788311.

Inhibiting Protein Kinase D Promotes Airway Epithelial Barrier Integrity in Mouse Models of Influenza A Virus Infection

Janelle M. Veazey, Sophia I Eliseeva, Sara E. Hillman, Kristie Stiles, Timothy R. Smyth, Charlotte E. Morrissey, Erika J. Tillotson, Dave J. Topham, Timothy J. Chapman, Steve N. Georas

Front Immunol. 2020; 11: 580401. Published online 2020 Dec 14. doi: 10.3389/fimmu.2020.580401

PMCID:: PMC7767883

Abstract Article PDF–2.7M

Select item 761214612.

The kinase PKD3 provides negative feedback on cholesterol and triglyceride synthesis by suppressing insulin signaling

Alexander E. Mayer, Mona C. Löffler, Angel E. Loza Valdés, Werner Schmitz, Rabih El-Merahbi, Jonathan Trujillo Viera, Manuela Erk, Thianzhou Zhang, Ursula Braun, Mathias Heikenwalder, Michael Leitges, Almut Schulze, Grzegorz Sumara

Sci Signal. Author manuscript; available in PMC 2022 Jan 3.

Published in final edited form as: Sci Signal. 2019 Aug 6; 12(593): eaav9150. Published online 2019 Aug 6. doi: 10.1126/scisignal.aav9150

PMCID:: PMC7612146

Abstract Article PDF–2.2M

Select item 660230013.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 505265314.

Protein kinase D regulates positive selection of CD4⁺ thymocytes through phosphorylation of SHP-1

Eri Ishikawa, Hidetaka Kosako, Tomoharu Yasuda, Masaki Ohmuraya, Kimi Araki, Tomohiro Kurosaki, Takashi Saito, Sho Yamasaki

Nat Commun. 2016; 7: 12756. Published online 2016 Sep 27. doi: 10.1038/ncomms12756

PMCID:: PMC5052653

Abstract Article PDF–1.8M

Select item 496889815.

PKD3 deficiency causes alterations in microtubule dynamics during the cell cycle

Tianzhou Zhang, Ursula Braun, Michael Leitges

Cell Cycle. 2016; 15(14): 1844–1854. Published online 2016 May 31. doi: 10.1080/15384101.2016.1188237

PMCID:: PMC4968898

Abstract Article PDF–980K

Select item 461808616.

The Interleukin-2-mTORc1 Axis Defines the Reciprocal Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells

John P. Ray, Matthew M. Staron, Justin A. Shyer, Ping-Chih Ho, Heather D. Marshall, Simon M. Gray, Brian J. Laidlaw, Koichi Araki, Rafi Ahmed, Susan M. Kaech, Joe Craft

Immunity. Author manuscript; available in PMC 2016 Oct 20.

Published in final edited form as: Immunity. 2015 Oct 20; 43(4): 690–702. Published online 2015 Sep 22. doi: 10.1016/j.immuni.2015.08.017

PMCID:: PMC4618086

Abstract Article PDF–2.2M

Select item 357241017.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163