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Select item 112813411.

TRIM5α: A Protean Architect of Viral Recognition and Innate Immunity

Stephanie J. Spada, Michael E. Grigg, Fadila Bouamr, Sonja M. Best, Peijun Zhang

Viruses. 2024 Jul; 16(7): 997. Published online 2024 Jun 21. doi: 10.3390/v16070997

PMCID:: PMC11281341

Abstract Article PDF–2.2M

Select item 112168662.

TBK1 is ubiquitinated by TRIM5α to assemble mitophagy machinery

Bhaskar Saha, Hallvard Olsvik, Geneva L Williams, Seeun Oh, Gry Evjen, Eva Sjøttem, Michael A Mandell

Cell Rep. Author manuscript; available in PMC 2024 Jul 2.

Published in final edited form as: Cell Rep. 2024 Jun 25; 43(6): 114294. Published online 2024 May 29. doi: 10.1016/j.celrep.2024.114294

PMCID:: PMC11216866

Abstract Article PDF–3.2M

Select item 109457073.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Abstract Article PDF–2.8M

Select item 104472394.

TRIM5α restricts poxviruses and is antagonized by CypA and the viral protein C6

Yiqi Zhao, Yongxu Lu, Samuel Richardson, Meghna Sreekumar, Jonas D. Albarnaz, Geoffrey L. Smith

Nature. 2023; 620(7975): 873–880. Published online 2023 Aug 9. doi: 10.1038/s41586-023-06401-0

PMCID:: PMC10447239

Abstract Article PDF–10M

Select item 103195605.

Increased TRIM5 is associated with a poor prognosis and immune infiltration in glioma patients

Yue CHEN, Qin LI, Jie ZHANG, Rui GU, Kai LI, Gang ZHAO, Hang YUAN, Tianyu FENG, Deqiong OU, Ping LIN

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2020 Jun; 37(3): 469–479. doi: 10.7507/1001-5515.202004064

PMCID:: PMC10319560

Abstract Article PDF–9.3M

Select item 102374226.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101696637.

A frequent SNP in TRIM5α strongly enhances the innate immune response against LINE-1 elements

Justine Lagisquet, Marcus Conrad, Sabine Wittmann, Bianca Volkmann, Hannah Weissinger, Heinrich Sticht, Thomas Gramberg

Front Immunol. 2023; 14: 1168589. Published online 2023 Apr 26. doi: 10.3389/fimmu.2023.1168589

PMCID:: PMC10169663

Abstract Article PDF–5.4M

Select item 101516158.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 98099369.

The retroviral restriction factor TRIM5/TRIM5α regulates mitochondrial quality control

Bhaskar Saha, Michael A. Mandell

Autophagy. 2023; 19(1): 372–373. Published online 2022 Jun 5. doi: 10.1080/15548627.2022.2084863

PMCID:: PMC9809936

Abstract Article PDF–342K

Select item 934857610.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 927928511.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 913694312.

Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy

Bhaskar Saha, Michelle Salemi, Geneva L. Williams, Seeun Oh, Michael L. Paffett, Brett Phinney, Michael A. Mandell

Cell Rep. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell Rep. 2022 May 10; 39(6): 110797. doi: 10.1016/j.celrep.2022.110797

PMCID:: PMC9136943

Abstract Article PDF–3.2M

Select item 910523513.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 887942314.

TRIM5α Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A Protection

Anastasia Selyutina, Lacy M. Simons, Karen A. Kirby, Angel Bulnes-Ramos, Pan Hu, Stefan G. Sarafianos, Judd F. Hultquist, Felipe Diaz-Griffero

Viruses. 2022 Feb; 14(2): 363. Published online 2022 Feb 10. doi: 10.3390/v14020363

PMCID:: PMC8879423

Abstract Article PDF–2.3M

Select item 884216515.

CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system

Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar

Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629

PMCID:: PMC8842165

Abstract Article PDF–3.0M

Select item 866614016.

TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation

Abhilash I. Chiramel, Nicholas R. Meyerson, Kristin L. McNally, Rebecca M. Broeckel, Vanessa R. Montoya, Omayra Méndez-Solís, Shelly J. Robertson, Gail L. Sturdevant, Kirk J. Lubick, Vinod Nair, Brian H. Youseff, Robin M. Ireland, Catharine M. Bosio, Kyusik Kim, Jeremy Luban, Vanessa M. Hirsch, R. Travis Taylor, Fadila Bouamr, Sara L. Sawyer, Sonja M. Best

Cell Rep. Author manuscript; available in PMC 2021 Dec 12.

Published in final edited form as: Cell Rep. 2019 Jun 11; 27(11): 3269–3283.e6. doi: 10.1016/j.celrep.2019.05.040

PMCID:: PMC8666140

Abstract Article PDF–2.9M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 794677118.

Knockdown of TRIM5α or TRIM11 Increases Lentiviral Vector Transduction Efficiency of Human Muller Cells

Monica M. Sauter, Curtis R. Brandt

Exp Eye Res. Author manuscript; available in PMC 2022 Mar 1.

Published in final edited form as: Exp Eye Res. 2021 Mar; 204: 108436. Published online 2021 Jan 10. doi: 10.1016/j.exer.2021.108436

PMCID:: PMC7946771

Abstract Article PDF–1.3M

Select item 792322919.

Human TRIM5α: Autophagy Connects Cell-Intrinsic HIV-1 Restriction and Innate Immune Sensor Functioning

Alexandra P. M. Cloherty, Anusca G. Rader, Brandon Compeer, Carla M. S. Ribeiro

Viruses. 2021 Feb; 13(2): 320. Published online 2021 Feb 19. doi: 10.3390/v13020320

PMCID:: PMC7923229

Abstract Article PDF–2.8M

Select item 787370120.

Global proteomics of Ubqln2-based murine models of ALS

Alexandra M. Whiteley, Miguel A. Prado, Stefanie A.H. de Poot, Joao A. Paulo, Marissa Ashton, Sara Dominguez, Martin Weber, Hai Ngu, John Szpyt, Mark P. Jedrychowski, Amy Easton, Steven P. Gygi, Thimo Kurz, Mervyn J. Monteiro, Eric J. Brown, Daniel Finley

J Biol Chem. 2021 Jan-Jun; 296: 100153. Published online 2020 Dec 10. doi: 10.1074/jbc.RA120.015960

PMCID:: PMC7873701

Abstract Article PDF–3.0M

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