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Select item 113025651.

ICOS-ICOSL pathway enhances NKT-like cell antiviral function in pregnant women with COVID-19

Lu Zong, Yuanling Zheng, Xiaojing Yu, Xiaoran Dai, Ruoyu Huang, Guoxiu Yan, Yuanhong Xu, Meijuan Zheng

Int J Med Sci. 2024; 21(10): 1890–1902. Published online 2024 Jul 16. doi: 10.7150/ijms.95952

PMCID:: PMC11302565

Abstract Article PDF–5.7M

Select item 108623632.

Epstein-Barr virus–encoded EBNA2 downregulates ICOSL by inducing miR-24 in B-cell lymphoma

Martina Leopizzi, Lucia Mundo, Elena Messina, Federica Campolo, Stefano Lazzi, Antonio Angeloni, Cinzia Marchese, Lorenzo Leoncini, Carla Giordano, Frank Slack, Pankaj Trivedi, Eleni Anastasiadou

Blood. 2024 Feb 1; 143(5): 429–443. Published online 2023 Oct 20. doi: 10.1182/blood.2023021346

PMCID:: PMC10862363

Abstract Article

Select item 107029743.

Role of the co-stimulatory molecule inducible T-cell co-stimulator ligand (ICOSL) in the progression of experimental metabolic dysfunction-associated steatohepatitis

Alessia Provera, Naresh Naik Ramavath, Laila Lavanya Gadipudi, Casimiro Luca Gigliotti, Elena Boggio, Cristina Vecchio, Ian Stoppa, Roberta Rolla, Renzo Boldorini, Mario Pirisi, Carlo Smirne, Emanuele Albano, Umberto Dianzani, Salvatore Sutti

Front Immunol. 2023; 14: 1290391. Published online 2023 Nov 22. doi: 10.3389/fimmu.2023.1290391

PMCID:: PMC10702974

Abstract Article PDF–4.6M

Select item 106141224.

Expression and prognosis of inducible T‐cell co‐stimulator and its ligand in Chinese stage I–III lung adenocarcinoma patients

Xiao‐Kai Zhan, Xi‐Kun Liu, Sen Zhang, Hong Chen

Animal Model Exp Med. 2023 Oct; 6(5): 464–473. Published online 2023 Oct 18. doi: 10.1002/ame2.12355

PMCID:: PMC10614122

Abstract Article PDF–3.6M

Select item 83600405.

Mesenchymal stem cells regulate type 2 innate lymphoid cells via regulatory T cells through ICOS‐ICOSL interaction

Xingliang Fan, Zhi‐Bin Xu, Cheng‐Lin Li, Hong‐Yu Zhang, Ya‐Qi Peng, Bi‐Xin He, Xiao‐Qing Liu, De‐Hua Chen, Dong Chen, Cezmi A. Akdis, Qing‐Ling Fu

Stem Cells. 2021 Jul; 39(7): 975–987. Published online 2021 Mar 19. doi: 10.1002/stem.3369

PMCID:: PMC8360040

Abstract Article PDF–4.1M

Select item 82361236.

Activated neutrophils polarize protumorigenic interleukin‐17A‐producing T helper subsets through TNF‐α‐B7‐H2‐dependent pathway in human gastric cancer

Zhi‐guo Shan, Jun Chen, Jin‐shan Liu, Jin‐yu Zhang, Ting‐ting Wang, Yong‐sheng Teng, Fang‐yuan Mao, Ping Cheng, Quan‐ming Zou, Wei‐ying Zhou, Liu‐sheng Peng, Yong‐liang Zhao, Yuan Zhuang

Clin Transl Med. 2021 Jun; 11(6): e484. Published online 2021 Jun 27. doi: 10.1002/ctm2.484

PMCID:: PMC8236123

Abstract Article PDF–14M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80185738.

Dysregulated NFκB-dependent ICOSL Expression in Human Dendritic Cell Vaccines Impairs T-cell Responses in Melanoma Patients

Deena M. Maurer, Juraj Adamik, Patricia M. Santos, Jian Shi, Michael R. Shurin, John M. Kirkwood, Walter J. Storkus, Lisa H. Butterfield

Cancer Immunol Res. Author manuscript; available in PMC 2021 Jun 1.

Published in final edited form as: Cancer Immunol Res. 2020 Dec; 8(12): 1554–1567. Published online 2020 Oct 13. doi: 10.1158/2326-6066.CIR-20-0274

PMCID:: PMC8018573

Abstract Article PDF–1.9M

Select item 75451899.

Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies

Edurne Rujas, Hong Cui, Taylor Sicard, Anthony Semesi, Jean-Philippe Julien

Nat Commun. 2020; 11: 5066. Published online 2020 Oct 8. doi: 10.1038/s41467-020-18828-4

PMCID:: PMC7545189

Abstract Article PDF–3.1M

Select item 697319710.

The ICOSL Expression Predicts Better Prognosis for Nasopharyngeal Carcinoma via Enhancing Oncoimmunity

Geng Zhang, Yi Xu, Sen Zhang, Huifang Zhou

Biomed Res Int. 2020; 2020: 9756732. Published online 2020 Jan 7. doi: 10.1155/2020/9756732

PMCID:: PMC6973197

Abstract Article PDF–5.5M

Select item 627939711.

Loss of human ICOSL results in combined immunodeficiency

Lucie Roussel, Marija Landekic, Makan Golizeh, Christina Gavino, Ming-Chao Zhong, Jun Chen, Denis Faubert, Alexis Blanchet-Cohen, Luc Dansereau, Marc-Antoine Parent, Sonia Marin, Julia Luo, Catherine Le, Brinley R. Ford, Mélanie Langelier, Irah L. King, Maziar Divangahi, William D. Foulkes, André Veillette, Donald C. Vinh

J Exp Med. 2018 Dec 3; 215(12): 3151–3164. doi: 10.1084/jem.20180668

PMCID:: PMC6279397

Abstract Article PDF–1.9M

Select item 616867712.

Acute Myeloid Leukemia Cells Express ICOS Ligand to Promote the Expansion of Regulatory T Cells

Yixiang Han, Yuqing Dong, Qianqian Yang, Wanling Xu, Songfu Jiang, Zhijie Yu, Kang Yu, Shenghui Zhang

Front Immunol. 2018; 9: 2227. Published online 2018 Sep 26. doi: 10.3389/fimmu.2018.02227

PMCID:: PMC6168677

Abstract Article PDF–5.4M

Select item 582692613.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 560544814.

ADAM10-mediated ICOSL Shedding on B cells is Necessary for Proper T cell ICOS Regulation and T_FH Responses

Joseph C Lownik, Andrea J. Luker, Sheela R. Damle, Lauren Folgosa Cooley, Riham El Sayed, Andreas Hutloff, Costantino Pitzalis, Rebecca K. Martin, Mohey Eldin M El Shikh, Daniel H. Conrad

J Immunol. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: J Immunol. 2017 Oct 1; 199(7): 2305–2315. Published online 2017 Aug 16. doi: 10.4049/jimmunol.1700833

PMCID:: PMC5605448

Abstract Article PDF–2.0M

Select item 553161115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 534952016.

ICOSL expression in human bone marrow-derived mesenchymal stem cells promotes induction of regulatory T cells

Hyun-Joo Lee, Si-Na Kim, Myung-Shin Jeon, TacGhee Yi, Sun U. Song

Sci Rep. 2017; 7: 44486. Published online 2017 Mar 14. doi: 10.1038/srep44486

PMCID:: PMC5349520

Abstract Article PDF–3.0M

Select item 464794117.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 461181918.

In situ expression and significance of B7 costimulatory molecules within tissues of human gastric carcinoma

Xiao-Li Chen, Xu-Dong Cao, An-Jing Kang, Kang-Min Wang, Bao-Shan Su, Yi-Li Wang

World J Gastroenterol. 2003 Jun 15; 9(6): 1370–1373. Published online 2003 Jun 15. doi: 10.3748/wjg.v9.i6.1370

PMCID:: PMC4611819

Abstract Article PDF–248K

Select item 436627119.

ICOS:ICOS-Ligand interaction is required for type 2 innate lymphoid cell function, homeostasis and induction of airway hyperreactivity

Hadi Maazi, Nisheel Patel, Ishwarya Sankaranarayanan, Yuzo Suzuki, Diamanda Rigas, Pejman Soroosh, Gordon J. Freeman, Arlene H. Sharpe, Omid Akbari

Immunity. Author manuscript; available in PMC 2016 Mar 17.

Published in final edited form as: Immunity. 2015 Mar 17; 42(3): 538–551. Published online 2015 Mar 10. doi: 10.1016/j.immuni.2015.02.007

PMCID:: PMC4366271

Abstract Article PDF–2.2M

Select item 426312520.

Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity

Katharina L. Willmann, Stefanie Klaver, Figen Doğu, Elisangela Santos-Valente, Wojciech Garncarz, Ivan Bilic, Emily Mace, Elisabeth Salzer, Cecilia Domínguez Conde, Heiko Sic, Peter Májek, Pinaki P. Banerjee, Gregory I. Vladimer, Şule Haskoloğlu, Musa Gökalp Bolkent, Alphan Küpesiz, Antonio Condino-Neto, Jacques Colinge, Giulio Superti-Furga, Winfried F. Pickl, Menno C. van Zelm, Hermann Eibel, Jordan S. Orange, Aydan Ikincioğulları, Kaan Boztuğ

Nat Commun. 2014 Nov 19; 5: 5360. Published online 2014 Nov 19. doi: 10.1038/ncomms6360

PMCID:: PMC4263125

Abstract Article PDF–2.2M

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