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Select item 109884941.

High preoperative bradykinin level is a risk factor for severe postoperative hypoxaemia in acute aortic dissection surgery

XinLiang Guan, Lei Li, JinZhang Li, WenJian Jiang, HaiYang Li, XiaoLong Wang, Lu Han, YuYong Liu, Ming Gong, HongJia Zhang

Exp Physiol. 2023 May; 108(5): 683–691. Published online 2023 Mar 19. doi: 10.1113/EP091054

PMCID:: PMC10988494

Abstract Article PDF–390K

Select item 107236472.

Bradykinin receptor expression and bradykinin-mediated sensitization of human sensory neurons

Jiwon Yi, Zachariah Bertels, John Smith Del Rosario, Allie J. Widman, Richard A. Slivicki, Maria Payne, Henry M. Susser, Bryan A. Copits, Robert W. Gereau, IV

Pain. 2024 Jan; 165(1): 202–215. Published online 2023 Sep 13. doi: 10.1097/j.pain.0000000000003013

PMCID:: PMC10723647

Abstract Article PDF–2.4M

Select item 104357663.

An HBV susceptibility variant of KNG1 modulates the therapeutic effects of interferons α and λ1 in HBV infection by promoting MAVS lysosomal degradation

Bin Zhang, Haijun Han, Xinyi Zhao, Andria N. Li, Yan Wang, Wenji Yuan, Zhongli Yang, Ming D. Li

eBioMedicine. 2023 Aug; 94: 104694. Published online 2023 Jul 11. doi: 10.1016/j.ebiom.2023.104694

PMCID:: PMC10435766

Abstract Article PDF–2.6M

Select item 102794694.

Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein

Sean A. Burnap, Ana Maria Ortega-Prieto, Jose M. Jimenez-Guardeño, Hashim Ali, Kaloyan Takov, Matthew Fish, Manu Shankar-Hari, Mauro Giacca, Michael H. Malim, Manuel Mayr

Mol Cell Proteomics. 2023 Aug; 22(8): 100600. Published online 2023 Jun 19. doi: 10.1016/j.mcpro.2023.100600

PMCID:: PMC10279469

Abstract Article PDF–3.2M

Select item 83104295.

Plasmin-mediated cleavage of high-molecular-weight kininogen contributes to acetaminophen-induced acute liver failure

Michael W. Henderson, Erica M. Sparkenbaugh, Shaobin Wang, Anton Ilich, Denis F. Noubouossie, Reiner Mailer, Thomas Renné, Matthew J. Flick, James P. Luyendyk, Zu-Lin Chen, Sidney Strickland, R. Todd Stravitz, Keith R. McCrae, Nigel S. Key, Rafal Pawlinski

Blood. 2021 Jul 22; 138(3): 259–272. Prepublished online 2021 Apr 7. doi: 10.1182/blood.2020006198

PMCID:: PMC8310429

Abstract Article

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80787287.

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics

Alexandra Naba, Oliver M. T. Pearce, Amanda Del Rosario, Duanduan Ma, Huiming Ding, Vinothini Rajeeve, Pedro R. Cutillas, Frances R. Balkwill, Richard O. Hynes

J Proteome Res. Author manuscript; available in PMC 2021 Apr 27.

Published in final edited form as: J Proteome Res. 2017 Aug 4; 16(8): 3083–3091. Published online 2017 Jul 19. doi: 10.1021/acs.jproteome.7b00191

PMCID:: PMC8078728

Abstract Article PDF–2.1M

Select item 76458188.

Impaired Breakdown of Bradykinin and Its Metabolites as a Possible Cause for Pulmonary Edema in COVID-19 Infection

Steven de Maat, Quirijn de Mast, A.H. Jan Danser, Frank L. van de Veerdonk, Coen Maas

Semin Thromb Hemost. 2020 Oct; 46(7): 835–837. Published online 2020 Jun 11. doi: 10.1055/s-0040-1712960

PMCID:: PMC7645818

Article PDF–134K

Select item 75984179.

Pathways for bradykinin formation and interrelationship with complement as a cause of edematous lung in COVID-19 patients

Allen P. Kaplan, Berhane Ghebrehiwet

J Allergy Clin Immunol. 2021 Feb; 147(2): 507–509. Published online 2020 Oct 28. doi: 10.1016/j.jaci.2020.10.025

PMCID:: PMC7598417

Article PDF–809K

Select item 738150410.

Kininogen supports inflammation and bacterial spreading during Streptococccus Pyogenes Sepsis

Juliane Köhler, Claudia Maletzki, Dirk Koczan, Marcus Frank, Armin Springer, Carolin Steffen, Alexey S. Revenko, A.Robert MacLeod, Stefan Mikkat, Bernd Kreikemeyer, Sonja Oehmcke-Hecht

EBioMedicine. 2020 Aug; 58: 102908. Published online 2020 Jul 21. doi: 10.1016/j.ebiom.2020.102908

PMCID:: PMC7381504

Abstract Article PDF–3.5M

Select item 726750611.

A hypothesized role for dysregulated bradykinin signaling in COVID‐19 respiratory complications

Joseph A. Roche, Renuka Roche

FASEB J. 2020 Jun; 34(6): 7265–7269. Published online 2020 May 2. doi: 10.1096/fj.202000967

PMCID:: PMC7267506

Abstract Article PDF–494K

Select item 701853512.

Differential Processing of High-Molecular-Weight Kininogen during Normal Pregnancy

Stephenie H. Droll, Yen-Michael Sheng Hsu, Steven K. Drake, Ashley Kim, Weixin Wang, Katherine R. Calvo, Zheng Cao, Tony Y Hu, Zhen Zhao

Rapid Commun Mass Spectrom. Author manuscript; available in PMC 2021 Apr 1.

Published in final edited form as: Rapid Commun Mass Spectrom. 2020 Apr; 34(Suppl 1): e8552. Published online 2020 Feb 11. doi: 10.1002/rcm.8552

PMCID:: PMC7018535

Abstract Article PDF–671K

Select item 682589813.

Prospective study of plasma high molecular weight kininogen and prekallikrein and incidence of coronary heart disease, ischemic stroke and heart failure

Romil R. Parikh, Aaron R. Folsom, Jeffrey R. Misialek, Wayne D. Rosamond, Patricia P. Chang, Weihong Tang, Mary Cushman

Thromb Res. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Thromb Res. 2019 Oct; 182: 89–94. Published online 2019 Aug 22. doi: 10.1016/j.thromres.2019.08.009

PMCID:: PMC6825898

Abstract Article PDF–259K

Select item 656162514.

Serum bradykinin levels as a diagnostic marker in cervical cancer with a potential mechanism to promote VEGF expression via BDKRB2

Ying Zhou, Wei Wang, Rui Wei, Guiying Jiang, Fei Li, Xi Chen, Xueqian Wang, Sixiang Long, Ding Ma, Ling Xi

Int J Oncol. 2019 Jul; 55(1): 131–141. Published online 2019 May 2. doi: 10.3892/ijo.2019.4792

PMCID:: PMC6561625

Abstract Article PDF–1.8M

Select item 625590415.

Genetic effects of BDKRB2 and KNG1 on deep venous thrombosis after orthopedic surgery and the potential mediator

Qingfeng Wang, Guoping Cheng, Xiaohui Wang, Dandan Wang, Yanmei Yang, Ke Chen, Jiumin Ye, Zhong Qing

Sci Rep. 2018; 8: 17332. Published online 2018 Nov 26. doi: 10.1038/s41598-018-34868-9

PMCID:: PMC6255904

Abstract Article PDF–1.3M

Select item 609091216.

Overexpression of the Kininogen-1 inhibits proliferation and induces apoptosis of glioma cells

Jinfang Xu, Jun Fang, Zhonghao Cheng, Longlong Fan, Weiwei Hu, Feng Zhou, Hong Shen

J Exp Clin Cancer Res. 2018; 37: 180. Published online 2018 Aug 2. doi: 10.1186/s13046-018-0833-0

PMCID:: PMC6090912

Abstract Article PDF–9.0M

Select item 570334817.

Genome-wide association study with additional genetic and post-transcriptional analyses reveals novel regulators of plasma factor XI levels

Bengt Sennblad, Saonli Basu, Johanna Mazur, Pierre Suchon, Angel Martinez-Perez, Astrid van Hylckama Vlieg, Vinh Truong, Yuhuang Li, Jesper R. Gådin, Weihong Tang, Vera Grossman, Hugoline G. de Haan, Niklas Handin, Angela Silveira, Juan Carlos Souto, Anders Franco-Cereceda, Pierre-Emmanuel Morange, France Gagnon, Jose Manuel Soria, Per Eriksson, Anders Hamsten, Lars Maegdefessel, Frits R. Rosendaal, Philipp Wild, Aaron R. Folsom, David-Alexandre Trégouët, Maria Sabater-Lleal

Hum Mol Genet. 2017 Feb 1; 26(3): 637–649. Published online 2017 Jan 4. doi: 10.1093/hmg/ddw401

PMCID:: PMC5703348

Abstract Article PDF–260K

Select item 553161118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 517899319.

The Central Role of KNG1 Gene as a Genetic Determinant of Coagulation Pathway-Related Traits: Exploring Metaphenotypes

Helena Brunel, Raimon Massanet, Angel Martinez-Perez, Andrey Ziyatdinov, Laura Martin-Fernandez, Juan Carlos Souto, Alexandre Perera, José Manuel Soria

PLoS One. 2016; 11(12): e0167187. Published online 2016 Dec 22. doi: 10.1371/journal.pone.0167187

PMCID:: PMC5178993

Abstract Article PDF–1.8M

Select item 508109620.

Glycoproteomics Reveals Decorin Peptides with Anti-Myostatin Activity in Human Atrial Fibrillation

Javier Barallobre-Barreiro, Shashi K. Gupta, Anna Zoccarato, Rika Kitazume-Taneike, Marika Fava, Xiaoke Yin, Tessa Werner, Marc N Hirt, Anna Zampetaki, Alessandro Viviano, Mei Chong, Marshall Bern, Antonios Kourliouros, Nieves Domenech, Peter Willeit, Ajay M Shah, Marjan Jahangiri, Liliana Schaefer, Jens W. Fischer, Renato V. Iozzo, Rosa Viner, Thomas Thum, Joerg Heineke, Antoine Kichler, Kinya Otsu, Manuel Mayr

Circulation. Author manuscript; available in PMC 2017 Mar 13.

Published in final edited form as: Circulation. 2016 Sep 13; 134(11): 817–832. Published online 2016 Aug 24. doi: 10.1161/CIRCULATIONAHA.115.016423

PMCID:: PMC5081096

Abstract Article PDF–2.5M

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