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Select item 111895211.

FLI1 is associated with regulation of DNA methylation and megakaryocytic differentiation in FPDMM caused by a RUNX1 transactivation domain mutation

Yuki Tanaka, Yuri Nakanishi, Erina Furuhata, Ken-ichi Nakada, Rino Maruyama, Harukazu Suzuki, Takahiro Suzuki

Sci Rep. 2024; 14: 14080. Published online 2024 Jun 18. doi: 10.1038/s41598-024-64829-4

PMCID:: PMC11189521

Abstract Article PDF–3.1M

Select item 110826412.

An intricate regulatory circuit between FLI1 and GATA1/GATA2/LDB1/ERG dictates erythroid vs. megakaryocytic differentiation

Chunlin Wang, Maoting Hu, Kunlin Yu, Wuling Liu, Anling Hu, Yi Kuang, Lei Huang, Babu Gajendran, Eldad Zacksenhaus, Xiao Xiao, Yaacov Ben-David

Mol Med Rep. 2024 Jun; 29(6): 107. Published online 2024 Apr 26. doi: 10.3892/mmr.2024.13231

PMCID:: PMC11082641

Abstract Article PDF–4.3M

Select item 109332673.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 109250004.

FLI1 induces erythroleukemia through opposing effects on UBASH3A and UBASH3B expression

Jie Wang, Chunlin Wang, Anling Hu, Kunlin Yu, Yi Kuang, Babu Gajendran, Eldad Zacksenhaus, Klarke Michael Sample, Xiao Xiao, Wuling Liu, Yaacov Ben-David

BMC Cancer. 2024; 24: 326. Published online 2024 Mar 9. doi: 10.1186/s12885-024-12075-2

PMCID:: PMC10925000

Abstract Article PDF–4.6M

Select item 109161245.

Integrated analysis reveals FLI1 regulates the tumor immune microenvironment via its cell-type-specific expression and transcriptional regulation of distinct target genes of immune cells in breast cancer

Jianying Pei, Ying Peng, Kexin Ma, Chunyan Lan, Tingting Zhang, Yan Li, Xiaofang Chen, Huafang Gao

BMC Genomics. 2024; 25: 250. Published online 2024 Mar 6. doi: 10.1186/s12864-024-10174-9

PMCID:: PMC10916124

Abstract Article PDF–9.8M

Select item 108218266.

FLI-1 is expressed in a wide variety of hematolymphoid neoplasms: a special concern in the differential diagnosis

Uiju Cho, Hee Jeong Cha, Hyun Jung Kim, Soo Kee Min, Hee Kyung Kim, Hye Ra Jung, Gyeongsin Park, Ji Eun Kim

Clin Exp Med. 2024; 24(1): 18. Published online 2024 Jan 27. doi: 10.1007/s10238-023-01284-x

PMCID:: PMC10821826

Abstract Article PDF–2.3M

Select item 105434187.

Role of the transcription factor Fli-1 on the CXCL10/CXCR3 Axis*

Xuan Wang, Mara Lennard Richard, Tomika S. Caldwell, Kamala Sundararaj, Shuzo Sato, Tamara K. Nowling, Xian K. Zhang

Front Immunol. 2023; 14: 1219279. Published online 2023 Sep 15. doi: 10.3389/fimmu.2023.1219279

PMCID:: PMC10543418

Abstract Article PDF–1.4M

Select item 105407698.

Friend leukemia integration 1 overexpression decreases endometrial receptivity and induces embryo implantation failure by promoting PART1 transcription in the endometrial epithelial cells

Yile Zhang, Beining Yin, Sichen Li, Yueyue Cui, Jianrong Liu

PeerJ. 2023; 11: e16105. Published online 2023 Sep 26. doi: 10.7717/peerj.16105

PMCID:: PMC10540769

Abstract Article PDF–10M

Select item 100945739.

Identification of Mir-182-3p/FLI-1 Axis as a Key Signaling in Immune Response in Cervical Cancer: A Comprehensive Bioinformatic Analysis

Eric Genaro Salmerón-Bárcenas, Miguel Angel Mendoza-Catalan, Ángela Uray Ramírez-Bautista, Rafael Acxel Lozano-Santos, Francisco Israel Torres-Rojas, Pedro Antonio Ávila-López, Ana Elvira Zacapala-Gómez

Int J Mol Sci. 2023 Apr; 24(7): 6032. Published online 2023 Mar 23. doi: 10.3390/ijms24076032

PMCID:: PMC10094573

Abstract Article PDF–3.3M

Select item 1002747310.

Targeted long-read sequencing of the Ewing sarcoma 6p25.1 susceptibility locus identifies germline-somatic interactions with EWSR1-FLI1 binding

Olivia W. Lee, Calvin Rodrigues, Shu-Hong Lin, Wen Luo, Kristine Jones, Derek W. Brown, Weiyin Zhou, Eric Karlins, Sairah M. Khan, Sylvain Baulande, Virginie Raynal, Didier Surdez, Stephanie Reynaud, Rebeca Alba Rubio, Sakina Zaidi, Sandrine Grossetête, Stelly Ballet, Eve Lapouble, Valérie Laurence, Gaelle Pierron, Nathalie Gaspar, Nadège Corradini, Perrine Marec-Bérard, Nathaniel Rothman, Casey L. Dagnall, Laurie Burdett, Michelle Manning, Kathleen Wyatt, Meredith Yeager, Raj Chari, Wendy M. Leisenring, Andreas E. Kulozik, Jennifer Kriebel, Thomas Meitinger, Konstantin Strauch, Thomas Kirchner, Uta Dirksen, Lisa Mirabello, Margaret A. Tucker, Franck Tirode, Gregory T. Armstrong, Smita Bhatia, Leslie L. Robison, Yutaka Yasui, Laura Romero-Pérez, Wolfgang Hartmann, Markus Metzler, W. Ryan Diver, Adriana Lori, Neal D. Freedman, Robert N. Hoover, Lindsay M. Morton, Stephen J. Chanock, Thomas G.P. Grünewald, Olivier Delattre, Mitchell J. Machiela

Am J Hum Genet. 2023 Mar 2; 110(3): 427–441. Published online 2023 Feb 13. doi: 10.1016/j.ajhg.2023.01.017

PMCID:: PMC10027473

Abstract Article PDF–2.4M

Select item 994574111.

FLI1 regulates radiotherapy resistance in nasopharyngeal carcinoma through TIE1-mediated PI3K/AKT signaling pathway

Enni Chen, Jiajia Huang, Miao Chen, Jiawei Wu, Puyun Ouyang, Xiaonan Wang, Dingbo Shi, Zhiqiao Liu, Wancui Zhu, Haohui Sun, Shanshan Yang, Baoyu Zhang, Wuguo Deng, Huijuan Qiu, Fangyun Xie

J Transl Med. 2023; 21: 134. Published online 2023 Feb 22. doi: 10.1186/s12967-023-03986-y

PMCID:: PMC9945741

Abstract Article PDF–12M

Select item 994110212.

FLI1 and FRA1 transcription factors drive the transcriptional regulatory networks characterizing muscle invasive bladder cancer

Perihan Yagmur Guneri-Sozeri, Gülden Özden-Yılmaz, Asli Kisim, Ece Cakiroglu, Aleyna Eray, Hamdiye Uzuner, Gökhan Karakülah, Devrim Pesen-Okvur, Serif Senturk, Serap Erkek-Ozhan

Commun Biol. 2023; 6: 199. Published online 2023 Feb 20. doi: 10.1038/s42003-023-04561-3

PMCID:: PMC9941102

Abstract Article PDF–2.0M

Select item 991538213.

Fli1 and Tissue Fibrosis in Various Diseases

Elena V. Mikhailova, Irina V. Romanova, Alexei Y. Bagrov, Natalia I. Agalakova

Int J Mol Sci. 2023 Feb; 24(3): 1881. Published online 2023 Jan 18. doi: 10.3390/ijms24031881

PMCID:: PMC9915382

Abstract Article PDF–747K

Select item 958860714.

EWS::FLI1 and HOXD13 control tumor cell plasticity in Ewing sarcoma

April A. Apfelbaum, Feinan Wu, Allegra G. Hawkins, Brian Magnuson, Jennifer A. Jiménez, Sean D. Taylor, Emma D. Wrenn, Olivia Waltner, Elise R. Pfaltzgraff, Jane Y. Song, Cody Hall, Deneen M. Wellik, Mats Ljungman, Scott N. Furlan, Russell J.H. Ryan, Jay F. Sarthy, Elizabeth R. Lawlor

Clin Cancer Res. Author manuscript; available in PMC 2023 Apr 14.

Published in final edited form as: Clin Cancer Res. 2022 Oct 14; 28(20): 4466–4478. doi: 10.1158/1078-0432.CCR-22-0384

PMCID:: PMC9588607

Abstract Article PDF–2.5M

Select item 954034515.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 952752016.

EGFR suppresses p53 function by promoting p53 binding to DNA-PKcs: a noncanonical regulatory axis between EGFR and wild-type p53 in glioblastoma

Jie Ding, Xiaolong Li, Sabbir Khan, Chen Zhang, Feng Gao, Shayak Sen, Amanda R Wasylishen, Yang Zhao, Guillermina Lozano, Dimpy Koul, W K Alfred Yung

Neuro Oncol. 2022 Oct; 24(10): 1712–1725. Published online 2022 Apr 26. doi: 10.1093/neuonc/noac105

PMCID:: PMC9527520

Abstract Article PDF–12M

Select item 882889517.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 844327318.

TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma

Bo Kyung A. Seong, Neekesh V. Dharia, Shan Lin, Katherine A. Donovan, Shasha Chong, Amanda Robichaud, Amy Conway, Amanda Hamze, Linda Ross, Gabriela Alexe, Biniam Adane, Behnam Nabet, Fleur M. Ferguson, Björn Stolte, Emily Jue Wang, Jialin Sun, Xavier Darzacq, Federica Piccioni, Nathanael S. Gray, Eric S. Fischer, Kimberly Stegmaier

Cancer Cell. 2021 Sep 13; 39(9): 1262–1278.e7. doi: 10.1016/j.ccell.2021.07.003

PMCID:: PMC8443273

Abstract Article

Select item 822039119.

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα

Evelyn Ramberger, Valeria Sapozhnikova, Elisabeth Kowenz-Leutz, Karin Zimmermann, Nathalie Nicot, Petr V. Nazarov, Daniel Perez-Hernandez, Ulf Reimer, Philipp Mertins, Gunnar Dittmar, Achim Leutz

iScience. 2021 Jun 25; 24(6): 102686. Published online 2021 Jun 4. doi: 10.1016/j.isci.2021.102686

PMCID:: PMC8220391

Abstract Article PDF–4.4M

Select item 813681520.

ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion

Olivier Saulnier, Katia Guedri-Idjouadiene, Marie-Ming Aynaud, Alina Chakraborty, Jonathan Bruyr, Joséphine Pineau, Tina O’Grady, Olivier Mirabeau, Sandrine Grossetête, Bartimée Galvan, Margaux Claes, Zahra Al Oula Hassoun, Benjamin Sadacca, Karine Laud, Sakina Zaïdi, Didier Surdez, Sylvain Baulande, Xavier Rambout, Franck Tirode, Martin Dutertre, Olivier Delattre, Franck Dequiedt

Nucleic Acids Res. 2021 May 21; 49(9): 5038–5056. Published online 2021 May 1. doi: 10.1093/nar/gkab305

PMCID:: PMC8136815

Abstract Article PDF–2.5M

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