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Select item 111157161.

HDAC3 selectively represses CREB3-mediated transcription and migration of metastatic breast cancer cells

Han-Cheon Kim, Kyung-Chul Choi, Hyo-Kyoung Choi, Hee-Bum Kang, Mi-Jeong Kim, Yoo-Hyun Lee, Ok-Hee Lee, Jeongmin Lee, Young Jun Kim, Woojin Jun, Jae-Wook Jeong, Ho-Geun Yoon

Cell Mol Life Sci. 2010 Oct; 67(20): 3499–3510. Published online 2010 May 15. doi: 10.1007/s00018-010-0388-5

PMCID:: PMC11115716

Abstract Article PDF–642K

Select item 109851012.

Dysregulated CREB3 cleavage at the nuclear membrane induces karyoptosis-mediated cell death

Ga-Eun Lee, Geul Bang, Jiin Byun, Cheol-Jung Lee, Weidong Chen, Dohyun Jeung, Hyun-Jung An, Han Chang Kang, Joo Young Lee, Hye Suk Lee, Young-Soo Hong, Dae Joon Kim, Megan Keniry, Jin Young Kim, Jin-Sung Choi, Manolis Fanto, Sung-Jun Cho, Kwang-Dong Kim, Yong-Yeon Cho

Exp Mol Med. 2024 Mar; 56(3): 686–699. Published online 2024 Mar 13. doi: 10.1038/s12276-024-01195-1

PMCID:: PMC10985101

Abstract Article PDF–7.3M

Select item 98519733.

A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets

Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu

Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.

Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0

PMCID:: PMC9851973

Abstract Article PDF–4.0M

Select item 92626144.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 92274615.

CREB3 Plays an Important Role in HPSE-Facilitated HSV-1 Release in Human Corneal Epithelial Cells

Tejabhiram Yadavalli, Pankaj Sharma, David Wu, Divya Kapoor, Deepak Shukla

Viruses. 2022 Jun; 14(6): 1171. Published online 2022 May 28. doi: 10.3390/v14061171

PMCID:: PMC9227461

Abstract Article PDF–1.8M

Select item 83732706.

Role of small leucine zipper protein in hepatic gluconeogenesis and metabolic disorder

Minsoo Kang, Sun Kyoung Han, Suhyun Kim, Sungyeon Park, Yerin Jo, Hyeryung Kang, Jesang Ko

J Mol Cell Biol. 2021 May; 13(5): 361–373. Published online 2020 Dec 23. doi: 10.1093/jmcb/mjaa069

PMCID:: PMC8373270

Abstract Article PDF–912K

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80090488.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 79671779.

Comparative Analysis of CREB3 and CREB3L2 Protein Expression in HEK293 Cells

Kentaro Oh-hashi, Ayumi Yamamoto, Ryoichi Murase, Yoko Hirata

Int J Mol Sci. 2021 Mar; 22(5): 2767. Published online 2021 Mar 9. doi: 10.3390/ijms22052767

PMCID:: PMC7967177

Abstract Article PDF–2.5M

Select item 681462310.

Knockdown of CREB3 activates endoplasmic reticulum stress and induces apoptosis in glioblastoma

Yaxin Hu, Liangzhao Chu, Jian Liu, Lei Yu, Shi-bin Song, Hua Yang, Feng Han

Aging (Albany NY) 2019 Oct 15; 11(19): 8156–8168. Published online 2019 Oct 13. doi: 10.18632/aging.102310

PMCID:: PMC6814623

Abstract Article PDF–2.0M

Select item 674264611.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 659888712.

Interplay between hepatitis C virus and ARF4

Na Zhang, Youyang Ke, Leiliang Zhang

Virol Sin. 2017 Dec; 32(6): 533–536. Published online 2017 Aug 18. doi: 10.1007/s12250-017-4000-0

PMCID:: PMC6598887

Abstract Article PDF–392K

Select item 644489013.

Circular RNA circTADA2A promotes osteosarcoma progression and metastasis by sponging miR-203a-3p and regulating CREB3 expression

Yizheng Wu, Ziang Xie, Junxin Chen, Jiaxin Chen, Weiyu Ni, Yan Ma, Kangmao Huang, Gangliang Wang, Jiying Wang, Jianjun Ma, Shuying Shen, Shunwu Fan

Mol Cancer. 2019; 18: 73. Published online 2019 Apr 2. doi: 10.1186/s12943-019-1007-1

PMCID:: PMC6444890

Abstract Article PDF–9.9M

Select item 631495714.

An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders

Siwei Chen, Robert Fragoza, Lambertus Klei, Yuan Liu, Jiebiao Wang, Kathryn Roeder, Bernie Devlin, Haiyuan Yu

Nat Genet. Author manuscript; available in PMC 2019 Jul 1.

Published in final edited form as: Nat Genet. 2018 Jul; 50(7): 1032–1040. Published online 2018 Jun 11. doi: 10.1038/s41588-018-0130-z

PMCID:: PMC6314957

Abstract Article PDF–1.3M

Select item 584480515.

A CREB3-regulated ER-Golgi trafficking signature promotes metastatic progression in breast cancer

Breege V Howley, Laura A Link, Simon Grelet, Maya El-Sabban, Philip H Howe

Oncogene. Author manuscript; available in PMC 2018 Jun 18.

Published in final edited form as: Oncogene. 2018 Mar; 37(10): 1308–1325. Published online 2017 Dec 18. doi: 10.1038/s41388-017-0023-0

PMCID:: PMC5844805

Abstract Article PDF–3.4M

Select item 553161116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366