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Select item 109332671.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 105658762.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 101516153.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 93485764.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 92626145.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 74273277.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 73687598.

Nuclear factor kappa B activation appears weaker in schizophrenia patients with high brain cytokines than in non-schizophrenic controls with high brain cytokines

Caitlin E. Murphy, Adam J. Lawther, Maree J. Webster, Makoto Asai, Yuji Kondo, Mitsuyuki Matsumoto, Adam K. Walker, Cynthia Shannon Weickert

J Neuroinflammation. 2020; 17: 215. Published online 2020 Jul 17. doi: 10.1186/s12974-020-01890-6

PMCID:: PMC7368759

Abstract Article PDF–1.2M

Select item 71132439.

Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity

Simone Kosol, Sara Contreras-Martos, Alessandro Piai, Mihaly Varadi, Tamas Lazar, Angela Bekesi, Pierre Lebrun, Isabella C. Felli, Roberta Pierattelli, Peter Tompa

Sci Rep. 2020; 10: 5753. Published online 2020 Apr 1. doi: 10.1038/s41598-020-62069-w

PMCID:: PMC7113243

Abstract Article PDF–4.2M

Select item 677809010.

Identification of HIVEP2 as a dopaminergic transcription factor related to substance use disorders in rats and humans

Juan Zhao, Chunnuan Chen, Richard L. Bell, Hong Qing, Zhicheng Lin

Transl Psychiatry. 2019; 9: 247. Published online 2019 Oct 4. doi: 10.1038/s41398-019-0573-8

PMCID:: PMC6778090

Abstract Article PDF–982K

Select item 637646811.

LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway

Yin-Li Zheng, Lei Li, Yong-Xun Jia, Bao-Zhu Zhang, Jiang-Chao Li, Ying-Hui Zhu, Meng-Qing Li, Jiao-Zi He, Ting-Ting Zeng, Xiao-Jiao Ban, Yun-Fei Yuan, Yan Li, Xin-Yuan Guan

Theranostics. 2019; 9(3): 796–810. Published online 2019 Jan 24. doi: 10.7150/thno.28992

PMCID:: PMC6376468

Abstract Article PDF–2.3M

Select item 634722412.

HIV-1 infection increases microRNAs that inhibit Dicer1, HRB and HIV-EP2, thereby reducing viral replication

Shira Modai, Luba Farberov, Eytan Herzig, Ofer Isakov, Amnon Hizi, Noam Shomron

PLoS One. 2019; 14(1): e0211111. Published online 2019 Jan 25. doi: 10.1371/journal.pone.0211111

PMCID:: PMC6347224

Abstract Article PDF–1.5M

Select item 597751413.

ZAS: C₂H₂ Zinc Finger Proteins Involved in Growth and Development

Lai-Chu Wu

Gene Expr. 2002; 10(4): 137–152. Published online 2018 May 31. doi: 10.3727/000000002783992479

PMCID:: PMC5977514

Abstract Article PDF–617K

Select item 582692614.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 553161115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 549522516.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 492987017.

Loss-of-function variants in HIVEP2 are a cause of intellectual disability

Siddharth Srivastava, Hartmut Engels, Ina Schanze, Kirsten Cremer, Thomas Wieland, Moritz Menzel, Max Schubach, Saskia Biskup, Martina Kreiß, Sabine Endele, Tim M Strom, Dagmar Wieczorek, Martin Zenker, Siddharth Gupta, Julie Cohen, Alexander M Zink, SakkuBai Naidu

Eur J Hum Genet. 2016 Apr; 24(4): 556–561. Published online 2015 Jul 8. doi: 10.1038/ejhg.2015.151

PMCID:: PMC4929870

Abstract Article PDF–615K

Select item 490784418.

Mutations in HIVEP2 are associated with developmental delay, intellectual disability and dysmorphic features

Hallie Steinfeld, Megan T. Cho, Kyle Retterer, Rick Person, G. Bradley Schaefer, Noelle Danylchuk, Saleem Malik, Stephanie Burns Wechsler, Patricia G. Wheeler, Koen L.I. van Gassen, P.A. Terhal, Virginie J.M. Verhoeven, Marjon A. van Slegtenhorst, Kristin G. Monaghan, Lindsay B. Henderson, Wendy K. Chung

Neurogenetics. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: Neurogenetics. 2016 Jul; 17(3): 159–164. Published online 2016 Mar 22. doi: 10.1007/s10048-016-0479-z

PMCID:: PMC4907844

Abstract Article PDF–222K

Select item 458732619.

BioID-based Identification of Skp Cullin F-box (SCF)^β-TrCP1/2 E3 Ligase Substrates

Etienne Coyaud, Monika Mis, Estelle M. N. Laurent, Wade H. Dunham, Amber L. Couzens, Melanie Robitaille, Anne-Claude Gingras, Stephane Angers, Brian Raught

Mol Cell Proteomics. 2015 Jul; 14(7): 1781–1795. Published online 2015 Apr 21. doi: 10.1074/mcp.M114.045658

PMCID:: PMC4587326

Abstract Article PDF–3.7M

Select item 447459920.

DNA Damage Regulates Translation through β-TRCP Targeting of CReP

Theresa B. Loveless, Benjamin R. Topacio, Ajay A. Vashisht, Shastyn Galaang, Katie M. Ulrich, Brian D. Young, James A. Wohlschlegel, David P. Toczyski

PLoS Genet. 2015 Jun; 11(6): e1005292. Published online 2015 Jun 19. doi: 10.1371/journal.pgen.1005292

PMCID:: PMC4474599

Abstract Article PDF–12M

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