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Select item 111057511.

Transcriptional and post-transcriptional regulation of the genes encoding the small GTPases RhoA, RhoB, and RhoC: implications for the pathogenesis of human diseases

Eirini Nomikou, Melina Livitsanou, Christos Stournaras, Dimitris Kardassis

Cell Mol Life Sci. 2018 Jun; 75(12): 2111–2124. Published online 2018 Mar 2. doi: 10.1007/s00018-018-2787-y

PMCID:: PMC11105751

Abstract Article PDF–1.4M

Select item 94822522.

RhoB affects colitis through modulating cell signaling and intestinal microbiome

Jianming Yang, Geng Pei, Xuan Sun, Yawen Xiao, Chunhui Miao, Lu Zhou, Bangmao Wang, Liu Yang, Mingyu Yu, Zhi-Song Zhang, Evan T. Keller, Zhi Yao, Quan Wang

Microbiome. 2022; 10: 149. Published online 2022 Sep 16. doi: 10.1186/s40168-022-01347-3

PMCID:: PMC9482252

Abstract Article PDF–19M

Select item 91197363.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 90360924.

Tumor suppressor BAP1 nuclear import is governed by transportin-1

Tzu-Jing Yang, Tian-Neng Li, Rih-Sheng Huang, Max Yu-Chen Pan, Shu-Yu Lin, Steven Lin, Kuen-Phon Wu, Lily Hui-Ching Wang, Shang-Te Danny Hsu

J Cell Biol. 2022 Jun 6; 221(6): e202201094. Published online 2022 Apr 21. doi: 10.1083/jcb.202201094

PMCID:: PMC9036092

Abstract Article PDF–4.0M

Select item 86230015.

A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry

Anh Phuong Luu, Zhenlan Yao, Sangeetha Ramachandran, Stephanie A. Azzopardi, Linde A. Miles, William M. Schneider, H.-Heinrich Hoffmann, Leonia Bozzacco, Gustavo Garcia, Jr., Danyang Gong, Robert Damoiseaux, Hengli Tang, Kouki Morizono, Charles M. Rudin, Ren Sun, Vaithilingaraja Arumugaswami, John T. Poirier, Margaret R. MacDonald, Charles M. Rice, Melody M. H. Li

Viruses. 2021 Nov; 13(11): 2113. Published online 2021 Oct 20. doi: 10.3390/v13112113

PMCID:: PMC8623001

Abstract Article PDF–2.2M

Select item 84529956.

Integrated Analysis of Prognostic Genes Associated With Ischemia–Reperfusion Injury in Renal Transplantation

Di Zhang, Yicun Wang, Song Zeng, Min Zhang, Xin Zhang, Yuxuan Wang, Zijian Zhang, Xi Wang, Xiaopeng Hu

Front Immunol. 2021; 12: 747020. Published online 2021 Sep 7. doi: 10.3389/fimmu.2021.747020

PMCID:: PMC8452995

Abstract Article PDF–3.7M

Select item 83217017.

CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP

Kanako Nishiyama, Masashi Maekawa, Tomoya Nakagita, Jun Nakayama, Takeshi Kiyoi, Mami Chosei, Akari Murakami, Yoshiaki Kamei, Hiroyuki Takeda, Yasutsugu Takada, Shigeki Higashiyama

Life Sci Alliance. 2021 Sep; 4(9): e202101095. Published online 2021 Jun 29. doi: 10.26508/lsa.202101095

PMCID:: PMC8321701

Abstract Article PDF–4.8M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81109569.

An infection-induced RhoB-Beclin 1-Hsp90 complex enhances clearance of uropathogenic Escherichia coli

Chunhui Miao, Mingyu Yu, Geng Pei, Zhenyi Ma, Lisong Zhang, Jianming Yang, Junqiang Lv, Zhi-Song Zhang, Evan T. Keller, Zhi Yao, Quan Wang

Nat Commun. 2021; 12: 2587. Published online 2021 May 10. doi: 10.1038/s41467-021-22726-8

PMCID:: PMC8110956

Abstract Article PDF–4.7M

Select item 794148110.

RhoB is regulated by hypoxia and modulates metastasis in breast cancer

Julia A. Ju, Inês Godet, Josh W. DiGiacomo, Daniele M. Gilkes

Cancer Rep (Hoboken) 2020 Feb; 3(1): e1164. Published online 2019 Feb 11. doi: 10.1002/cnr2.1164

Correction in:: Cancer Rep (Hoboken). 2021 Apr; 4(2): e1338.

PMCID:: PMC7941481

Abstract Article PDF–1.5M

Select item 764533811.

A high expression ratio of RhoA/RhoB is associated with the migratory and invasive properties of basal-like Breast Tumors

Maud Privat, Amélie Cavard, Yanis Zekri, Flora Ponelle-Chachuat, Ioana Molnar, Nicolas Sonnier, Yves-Jean Bignon

Int J Med Sci. 2020; 17(17): 2799–2808. Published online 2020 Oct 1. doi: 10.7150/ijms.43101

PMCID:: PMC7645338

Abstract Article PDF–1.0M

Select item 754962612.

Endothelial RhoB and RhoC are dispensable for leukocyte diapedesis and for maintaining vascular integrity during diapedesis

Lilian Schimmel, Aafke de Ligt, Simon Tol, Vivian de Waard, Jaap D. van Buul

Small GTPases. 2020; 11(3): 225–232. Published online 2017 Sep 29. doi: 10.1080/21541248.2017.1377815

PMCID:: PMC7549626

Abstract Article PDF–1.1M

Select item 682965313.

Arf6 regulates RhoB subcellular localization to control cancer cell invasion

Kossay Zaoui, Charles V. Rajadurai, Stéphanie Duhamel, Morag Park

J Cell Biol. 2019 Nov 4; 218(11): 3812–3826. Published online 2019 Oct 7. doi: 10.1083/jcb.201806111

PMCID:: PMC6829653

Abstract Article PDF–3.2M

Select item 674837814.

RhoA, RhoB and RhoC differentially regulate endothelial barrier function

Manon C. A. Pronk, Jan S. M. van Bezu, Geerten P. van Nieuw Amerongen, Victor W. M. van Hinsbergh, Peter L. Hordijk

Small GTPases. 2019 Nov; 10(6): 466–484. Published online 2017 Sep 26. doi: 10.1080/21541248.2017.1339767

PMCID:: PMC6748378

Abstract Article PDF–1.9M

Select item 660091515.

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile

Karen Dendoncker, Steven Timmermans, Jolien Vandewalle, Melanie Eggermont, Joanna Lempiäinen, Evelien Van Hamme, Sylviane Dewaele, Sofie Vandevyver, Marlies Ballegeer, Jolien Souffriau, Lise Van Wyngene, Kelly Van Looveren, Tineke Vanderhaeghen, Rudi Beyaert, Karolien De Bosscher, Jorma J. Palvimo, Marc Van Montagu, Claude Libert

Proc Natl Acad Sci U S A. 2019 Jun 25; 116(26): 12942–12951. Published online 2019 Jun 10. doi: 10.1073/pnas.1821565116

Correction in:: Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15745.

PMCID:: PMC6600915

Abstract Article PDF–1.7M

Select item 658970216.

FBXW7 regulates endothelial barrier function by suppression of the cholesterol synthesis pathway and prenylation of RhoB

Manon C. A. Pronk, Jisca Majolée, Anke Loregger, Jan S. M. van Bezu, Noam Zelcer, Peter L. Hordijk, Igor Kovačević

Mol Biol Cell. 2019 Mar 1; 30(5): 607–621. doi: 10.1091/mbc.E18-04-0259

PMCID:: PMC6589702

Abstract Article PDF–8.2M

Select item 654466017.

CSN5 inhibition triggers inflammatory signaling and Rho/ROCK-dependent loss of endothelial integrity

Jisca Majolée, Manon C. A. Pronk, Kin K. Jim, Jan S. M. van Bezu, Astrid M. van der Sar, Peter L. Hordijk, Igor Kovačević

Sci Rep. 2019; 9: 8131. Published online 2019 May 31. doi: 10.1038/s41598-019-44595-4

PMCID:: PMC6544660

Abstract Article PDF–2.5M

Select item 650411918.

Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer‐related pathways in breast cancer

Yan Liu, Jian Li, Zhifang Ma, Jun Zhang, Yuzhi Wang, Zhenghong Yu, Xue Lin, Zhi Xu, Qian Su, Li An, Yehui Zhou, Xinxing Ma, Yiwen Yang, Feifei Wang, Qingfei Chen, Yunchao Zhang, Jilinlin Wang, Huilin Zheng, Aihua Shi, Shuang Yu, Jingzhong Zhang, Weiyong Zhao, Liming Chen

Cancer Med. 2019 Feb; 8(2): 729–741. Published online 2019 Jan 16. doi: 10.1002/cam4.1938

PMCID:: PMC6504119

Abstract Article PDF–1.3M

Select item 644249119.

Atorvastatin Inhibits Breast Cancer Cells by Downregulating PTEN/AKT Pathway via Promoting Ras Homolog Family Member B (RhoB)

Qing Ma, Yang Gao, Pei Xu, Kai Li, Xiaolong Xu, Jingbo Gao, Yuwen Qi, Jingjing Xu, Yan Yang, Wenjing Song, Xin He, Shuting Liu, Xiaoning Yuan, Weinan Yin, Yanqi He, Wenting Pan, Lei Wei, Jingwei Zhang

Biomed Res Int. 2019; 2019: 3235021. Published online 2019 Mar 18. doi: 10.1155/2019/3235021

PMCID:: PMC6442491

Abstract Article PDF–5.8M

Select item 639360320.

A cell-based high-throughput screening method based on a ubiquitin-reference technique for identifying modulators of E3 ligases

Maoyuan Tian, Taoling Zeng, Mingdong Liu, Shang Han, Huayue Lin, Qi Lin, Li Li, Tingting Jiang, Gao Li, Hong Lin, Ting Zhang, Qiaofeng Kang, Xianming Deng, Hong-Rui Wang

J Biol Chem. 2019 Feb 22; 294(8): 2880–2891. Published online 2018 Dec 26. doi: 10.1074/jbc.RA118.003822

PMCID:: PMC6393603

Abstract Article PDF–5.5M

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