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Items: 1 to 20 of 41

1.
DYRK1B regulates Hedgehog-induced microtubule acetylation
Rajeev Singh, Philipp Simon Holz, Katrin Roth, Anna Hupfer, Wolfgang Meissner, Rolf Müller, Malte Buchholz, Thomas M. Gress, Hans-Peter Elsässer, Ralf Jacob, Matthias Lauth
Cell Mol Life Sci. 2019 Jan; 76(1): 193–207. Published online 2018 Oct 13. doi: 10.1007/s00018-018-2942-5
PMCID:
PMC11105311
AbstractArticlePDF–8.2M
2.
Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets
Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson
Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8
PMCID:
PMC10499821
AbstractArticlePDF–2.6M
3.
CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment
Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini
Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3
PMCID:
PMC9950183
AbstractArticlePDF–2.4M
4.
The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang
J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009
PMCID:
PMC9058836
AbstractArticlePDF–2.9M
5.
Differential maturation and chaperone dependence of the paralogous protein kinases DYRK1A and DYRK1B
Marco Papenfuss, Svenja Lützow, Gerrit Wilms, Aaron Babendreyer, Maren Flaßhoff, Conrad Kunick, Walter Becker
Sci Rep. 2022; 12: 2393. Published online 2022 Feb 14. doi: 10.1038/s41598-022-06423-0
PMCID:
PMC8844047
AbstractArticlePDF–5.8M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
Proline hydroxylation primes protein kinases for autophosphorylation and activation
Sang Bae Lee, Aram Ko, Young Taek Oh, Peiguo Shi, Fulvio D’Angelo, Brulinda Frangaj, Antonius Koller, Emily I. Chen, Timothy Cardozo, Antonio lavarone, Anna Lasorella
Mol Cell. Author manuscript; available in PMC 2021 Aug 6.
Published in final edited form as: Mol Cell. 2020 Aug 6; 79(3): 376–389.e8. Published online 2020 Jul 7. doi: 10.1016/j.molcel.2020.06.021
PMCID:
PMC7849370
AbstractArticlePDF–1.1M
8.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
9.
Screen identifies DYRK1B network as mediator of transcription repression on damaged chromatin
Chao Dong, Kirk L. West, Xin Yi Tan, Junshi Li, Toyotaka Ishibashi, Cheng-han Yu, Shirley M. H. Sy, Justin W. C. Leung, Michael S. Y. Huen
Proc Natl Acad Sci U S A. 2020 Jul 21; 117(29): 17019–17030. Published online 2020 Jul 1. doi: 10.1073/pnas.2002193117
PMCID:
PMC7382216
AbstractArticlePDF–2.6M
10.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
11.
DCAF7/WDR68 is required for normal levels of DYRK1A and DYRK1B
Mina Yousefelahiyeh, Jingyi Xu, Estibaliz Alvarado, Yang Yu, David Salven, Robert M. Nissen
PLoS One. 2018; 13(11): e0207779. Published online 2018 Nov 29. doi: 10.1371/journal.pone.0207779
PMCID:
PMC6264848
AbstractArticlePDF–2.6M
12.
The tumor suppressor CIC directly regulates MAPK pathway genes via histone deacetylation
Simon Weissmann, Paul A. Cloos, Simone Sidoli, Ole N. Jensen, Steven Pollard, Kristian Helin
Cancer Res. Author manuscript; available in PMC 2019 Feb 1.
Published in final edited form as: Cancer Res. 2018 Aug 1; 78(15): 4114–4125. Published online 2018 May 29. doi: 10.1158/0008-5472.CAN-18-0342
PMCID:
PMC6076439
AbstractArticlePDF–2.5M
13.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
14.
DYRK1B mutations associated with metabolic syndrome impair the chaperone-dependent maturation of the kinase domain
Samira Abu Jhaisha, Esti W. Widowati, Isao Kii, Rie Sonamoto, Stefan Knapp, Chrisovalantis Papadopoulos, Walter Becker
Sci Rep. 2017; 7: 6420. Published online 2017 Jul 25. doi: 10.1038/s41598-017-06874-w
PMCID:
PMC5526990
AbstractArticlePDF–2.2M
15.
Dual-utility NLS drives RNF169-dependent DNA damage responses
Liwei An, Yiyang Jiang, Howin H. W. Ng, Ellen P. S. Man, Jie Chen, Ui-Soon Khoo, Qingguo Gong, Michael S. Y. Huen
Proc Natl Acad Sci U S A. 2017 Apr 4; 114(14): E2872–E2881. Published online 2017 Mar 21. doi: 10.1073/pnas.1616602114
PMCID:
PMC5389323
AbstractArticlePDF–1.6M
16.
An ID2-dependent mechanism for VHL inactivation in cancer
Sang Bae Lee, Veronique Frattini, Mukesh Bansal, Angelica M. Castano, Dan Sherman, Keino Hutchinson, Jeffrey N. Bruce, Andrea Califano, Guangchao Liu, Timothy Cardozo, Antonio Iavarone, Anna Lasorella
Nature. Author manuscript; available in PMC 2017 Apr 7.
Published in final edited form as: Nature. 2016 Jan 14; 529(7585): 172–177. Published online 2016 Jan 6. doi: 10.1038/nature16475
PMCID:
PMC5384647
AbstractArticlePDF–1.3M
17.
The adaptor protein DCAF7 mediates the interaction of the adenovirus E1A oncoprotein with the protein kinases DYRK1A and HIPK2
Florian Glenewinkel, Michael J. Cohen, Cason R. King, Sophie Kaspar, Simone Bamberg-Lemper, Joe S. Mymryk, Walter Becker
Sci Rep. 2016; 6: 28241. Published online 2016 Jun 16. doi: 10.1038/srep28241
PMCID:
PMC4910162
AbstractArticlePDF–2.1M
18.
DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance
Wolfgang Gruber, Martin Hutzinger, Dominik Patrick Elmer, Thomas Parigger, Christina Sternberg, Lukasz Cegielkowski, Mirko Zaja, Johann Leban, Susanne Michel, Svetlana Hamm, Daniel Vitt, Fritz Aberger
Oncotarget. 2016 Feb 9; 7(6): 7134–7148. Published online 2016 Jan 13. doi: 10.18632/oncotarget.6910
PMCID:
PMC4872774
AbstractArticlePDF–4.2M
19.
Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome
Anne L. Ashford, Tom P. J. Dunkley, Mark Cockerill, Rachel A. Rowlinson, Lisa M. Baak, Raffaella Gallo, Kathryn Balmanno, Louise M. Goodwin, Richard A. Ward, Pamela A. Lochhead, Sylvie Guichard, Kevin Hudson, Simon J. Cook
Cell Mol Life Sci. 2016 Feb; 73(4): 883–900. Published online 2015 Sep 7. doi: 10.1007/s00018-015-2032-x
PMCID:
PMC4735261
AbstractArticlePDF–2.3M
20.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M

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