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Items: 1 to 20 of 31

1.
Concurrent anxiety in patients with major depression and cerebral serotonin 4 receptor binding. A NeuroPharm-1 study
Kristin Köhler-Forsberg, Brice Ozenne, Søren V. Larsen, Asbjørn S. Poulsen, Elizabeth B. Landman, Vibeke H. Dam, Cheng-Teng Ip, Anders Jørgensen, Claus Svarer, Gitte M. Knudsen, Vibe G. Frokjaer, Martin B. Jørgensen
Transl Psychiatry. 2022; 12: 273. Published online 2022 Jul 11. doi: 10.1038/s41398-022-02034-5
PMCID:
PMC9276803
AbstractArticlePDF–1.2M
2.
Gut bacteria-derived 5-hydroxyindole is a potent stimulant of intestinal motility via its action on L-type calcium channels
Barbora Waclawiková, Amber Bullock, Markus Schwalbe, Carmen Aranzamendi, Sieger A. Nelemans, Gertjan van Dijk, Sahar El Aidy
PLoS Biol. 2021 Jan; 19(1): e3001070. Published online 2021 Jan 22. doi: 10.1371/journal.pbio.3001070
PMCID:
PMC7857600
AbstractArticlePDF–2.0M
3.
Association of human serotonin receptor 4 promoter methylation with autism spectrum disorder
Zhenyu Hu, Xiuru Ying, Ling Huang, Yuanzhi Zhao, Dongsheng Zhou, Jing Liu, Jie Zhong, Tianyi Huang, Wenwu Zhang, Fang Cheng, Shiwei Duan
Medicine (Baltimore) 2020 Jan; 99(4): e18838. Published online 2020 Jan 24. doi: 10.1097/MD.0000000000018838
PMCID:
PMC7004686
AbstractArticlePDF–683K
4.
miR-16 and miR-103 impact 5-HT4 receptor signalling and correlate with symptom profile in irritable bowel syndrome
Carolin Wohlfarth, Stefanie Schmitteckert, Janina D. Härtle, Lesley A. Houghton, Harsh Dweep, Marina Fortea, Ghazaleh Assadi, Alexander Braun, Tanja Mederer, Sarina Pöhner, Philip P. Becker, Christine Fischer, Martin Granzow, Hubert Mönnikes, Emeran A. Mayer, Gregory Sayuk, Guy Boeckxstaens, Mira M. Wouters, Magnus Simrén, Greger Lindberg, Bodil Ohlsson, Peter Thelin Schmidt, Aldona Dlugosz, Lars Agreus, Anna Andreasson, Mauro D’Amato, Barbara Burwinkel, Justo Lorenzo Bermejo, Ralph Röth, Felix Lasitschka, Maria Vicario, Marco Metzger, Javier Santos, Gudrun A. Rappold, Cristina Martinez, Beate Niesler
Sci Rep. 2017; 7: 14680. Published online 2017 Oct 31. doi: 10.1038/s41598-017-13982-0
PMCID:
PMC5665867
AbstractArticlePDF–3.4M
5.
Brain serotonin 4 receptor binding is inversely associated with verbal memory recall
Dea S. Stenbæk, Patrick M. Fisher, Brice Ozenne, Emil Andersen, Liv V. Hjordt, Brenda McMahon, Steen G. Hasselbalch, Vibe G. Frokjaer, Gitte M. Knudsen
Brain Behav. 2017 Apr; 7(4): e00674. Published online 2017 Mar 17. doi: 10.1002/brb3.674
PMCID:
PMC5390847
AbstractArticlePDF–478K
6.
Systematic protein–protein interaction mapping for clinically relevant human GPCRs
Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar
Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430
PMCID:
PMC5371730
AbstractArticlePDF–4.1M
7.
Differences in the Control of Secondary Peristalsis in the Human Esophagus: Influence of the 5-HT4 Receptor versus the TRPV1 Receptor
Chih-Hsun Yi, Wei-Yi Lei, Jui-Sheng Hung, Tso-Tsai Liu, William C. Orr, Pace Fabio, Chien-Lin Chen
PLoS One. 2016; 11(7): e0159452. Published online 2016 Jul 20. doi: 10.1371/journal.pone.0159452
PMCID:
PMC4954651
AbstractArticlePDF–430K
8.
Familial Risk for Major Depression is Associated with Lower Striatal 5-HT4 Receptor Binding
Karine Madsen, Eva Torstensen, Klaus K. Holst, Mette E. Haahr, Ulla Knorr, Vibe G. Frokjaer, Malene Brandt-Larsen, Pernille Iversen, Patrick M. Fisher, Gitte M. Knudsen
Int J Neuropsychopharmacol. 2015 Jan; 18(1): pyu034. Published online 2014 Dec 19. doi: 10.1093/ijnp/pyu034
Correction in:
Int J Neuropsychopharmacol. 2016 Oct; 19(10): pyw031.
PMCID:
PMC4368872
AbstractArticlePDF–678K
9.
Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory
Anna G. Orr, Edward C. Hsiao, Max M. Wang, Kaitlyn Ho, Daniel H. Kim, Xin Wang, Weikun Guo, Jing Kang, Gui-Qiu Yu, Anthony Adame, Nino Devidze, Dena B. Dubal, Eliezer Masliah, Bruce R. Conklin, Lennart Mucke
Nat Neurosci. Author manuscript; available in PMC 2015 Sep 1.
Published in final edited form as: Nat Neurosci. 2015 Mar; 18(3): 423–434. Published online 2015 Jan 26. doi: 10.1038/nn.3930
PMCID:
PMC4340760
AbstractArticlePDF–1.9M
10.
Genetic variation in HTR4 and lung function: GWAS follow-up in mouse
John S. House, Huiling Li, Laura M. DeGraff, Gordon Flake, Darryl C. Zeldin, Stephanie J. London
FASEB J. 2015 Jan; 29(1): 323–335. Published online 2014 Oct 23. doi: 10.1096/fj.14-253898
PMCID:
PMC4285547
AbstractArticle
11.
ADAM19 and HTR4 Variants and Pulmonary Function: The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study
Stephanie J. London, Wei Gao, Sina A. Gharib, Dana B. Hancock, Jemma B. Wilk, John S. House, Richard A. Gibbs, Donna M. Muzny, Thomas Lumley, Nora Franceschini, Kari E. North, Bruce M. Psaty, Christie L. Kovar, Josef Coresh, Yanhua Zhou, Susan R. Heckbert, Jennifer A. Brody, Alanna C. Morrison, Josée Dupuis
Circ Cardiovasc Genet. Author manuscript; available in PMC 2015 Jun 1.
Published in final edited form as: Circ Cardiovasc Genet. 2014 Jun; 7(3): 350–358. doi: 10.1161/CIRCGENETICS.113.000066
PMCID:
PMC4136502
AbstractArticlePDF–572K
12.
HTR4 gene structure and altered expression in the developing lung
Emily Hodge, Carl P Nelson, Suzanne Miller, Charlotte K Billington, Ceri E Stewart, Caroline Swan, Anders Malarstig, Amanda P Henry, Catherine Gowland, Erik Melén, Ian P Hall, Ian Sayers
Respir Res. 2013; 14(1): 77. Published online 2013 Jul 26. doi: 10.1186/1465-9921-14-77
PMCID:
PMC3750317
AbstractArticlePDF–2.6M
13.
A novel regulator of angiogenesis in endothelial cells: 5-hydroxytriptamine 4 receptor
Jasmina Profirovic, Elena Strekalova, Norifumi Urao, Aleksandar Krbanjevic, Alexandra Andreeva, Sudhahar Varadarajan, Tohru Fukai, René Hen, Masuko Ushio-Fukai, Tatyana A. Voyno-Yasenetskaya
Angiogenesis. Author manuscript; available in PMC 2014 Jan 1.
Published in final edited form as: Angiogenesis. 2013 Jan; 16(1): 15–28. Published online 2012 Aug 18. doi: 10.1007/s10456-012-9296-7
PMCID:
PMC3656662
AbstractArticlePDF–4.5M
14.
Genome-Wide Joint Meta-Analysis of SNP and SNP-by-Smoking Interaction Identifies Novel Loci for Pulmonary Function
Dana B. Hancock, María Soler Artigas, Sina A. Gharib, Amanda Henry, Ani Manichaikul, Adaikalavan Ramasamy, Daan W. Loth, Medea Imboden, Beate Koch, Wendy L. McArdle, Albert V. Smith, Joanna Smolonska, Akshay Sood, Wenbo Tang, Jemma B. Wilk, Guangju Zhai, Jing Hua Zhao, Hugues Aschard, Kristin M. Burkart, Ivan Curjuric, Mark Eijgelsheim, Paul Elliott, Xiangjun Gu, Tamara B. Harris, Christer Janson, Georg Homuth, Pirro G. Hysi, Jason Z. Liu, Laura R. Loehr, Kurt Lohman, Ruth J. F. Loos, Alisa K. Manning, Kristin D. Marciante, Ma'en Obeidat, Dirkje S. Postma, Melinda C. Aldrich, Guy G. Brusselle, Ting-hsu Chen, Gudny Eiriksdottir, Nora Franceschini, Joachim Heinrich, Jerome I. Rotter, Cisca Wijmenga, O. Dale Williams, Amy R. Bentley, Albert Hofman, Cathy C. Laurie, Thomas Lumley, Alanna C. Morrison, Bonnie R. Joubert, Fernando Rivadeneira, David J. Couper, Stephen B. Kritchevsky, Yongmei Liu, Matthias Wjst, Louise V. Wain, Judith M. Vonk, André G. Uitterlinden, Thierry Rochat, Stephen S. Rich, Bruce M. Psaty, George T. O'Connor, Kari E. North, Daniel B. Mirel, Bernd Meibohm, Lenore J. Launer, Kay-Tee Khaw, Anna-Liisa Hartikainen, Christopher J. Hammond, Sven Gläser, Jonathan Marchini, Peter Kraft, Nicholas J. Wareham, Henry Völzke, Bruno H. C. Stricker, Timothy D. Spector, Nicole M. Probst-Hensch, Deborah Jarvis, Marjo-Riitta Jarvelin, Susan R. Heckbert, Vilmundur Gudnason, H. Marike Boezen, R. Graham Barr, Patricia A. Cassano, David P. Strachan, Myriam Fornage, Ian P. Hall, Josée Dupuis, Martin D. Tobin, Stephanie J. London
PLoS Genet. 2012 Dec; 8(12): e1003098. Published online 2012 Dec 20. doi: 10.1371/journal.pgen.1003098
PMCID:
PMC3527213
AbstractArticlePDF–417K
15.
Genome-Wide Association Studies Identify CHRNA5/3 and HTR4 in the Development of Airflow Obstruction
Jemma B. Wilk, Nick R. G. Shrine, Laura R. Loehr, Jing Hua Zhao, Ani Manichaikul, Lorna M. Lopez, Albert Vernon Smith, Susan R. Heckbert, Joanna Smolonska, Wenbo Tang, Daan W. Loth, Ivan Curjuric, Jennie Hui, Michael H. Cho, Jeanne C. Latourelle, Amanda P. Henry, Melinda Aldrich, Per Bakke, Terri H. Beaty, Amy R. Bentley, Ingrid B. Borecki, Guy G. Brusselle, Kristin M. Burkart, Ting-hsu Chen, David Couper, James D. Crapo, Gail Davies, Josée Dupuis, Nora Franceschini, Amund Gulsvik, Dana B. Hancock, Tamara B. Harris, Albert Hofman, Medea Imboden, Alan L. James, Kay-Tee Khaw, Lies Lahousse, Lenore J. Launer, Augusto Litonjua, Yongmei Liu, Kurt K. Lohman, David A. Lomas, Thomas Lumley, Kristin D. Marciante, Wendy L. McArdle, Bernd Meibohm, Alanna C. Morrison, Arthur W. Musk, Richard H. Myers, Kari E. North, Dirkje S. Postma, Bruce M. Psaty, Stephen S. Rich, Fernando Rivadeneira, Thierry Rochat, Jerome I. Rotter, María Soler Artigas, John M. Starr, André G. Uitterlinden, Nicholas J. Wareham, Cisca Wijmenga, Pieter Zanen, Michael A. Province, Edwin K. Silverman, Ian J. Deary, Lyle J. Palmer, Patricia A. Cassano, Vilmundur Gudnason, R. Graham Barr, Ruth J. F. Loos, David P. Strachan, Stephanie J. London, H. Marike Boezen, Nicole Probst-Hensch, Sina A. Gharib, Ian P. Hall, George T. O’Connor, Martin D. Tobin, Bruno H. Stricker
Am J Respir Crit Care Med. 2012 Oct 1; 186(7): 622–632. Published online 2012 Oct 1. doi: 10.1164/rccm.201202-0366OC
PMCID:
PMC3480517
AbstractArticlePDF–770K
16.
Activation of Colonic Mucosal 5-HT4 Receptors Accelerates Propulsive Motility and Inhibits Visceral Hypersensitivity
JILL M. HOFFMAN, KARL TYLER, SARAH J. MACEACHERN, ONESMO B. BALEMBA, ANTHONY C. JOHNSON, ELICE M. BROOKS, HONG ZHAO, GREG M. SWAIN, PETER L. MOSES, JAMES J. GALLIGAN, KEITH A. SHARKEY, BEVERLEY GREENWOOD–VAN MEERVELD, GARY M. MAWE
Gastroenterology. Author manuscript; available in PMC 2013 Apr 1.
Published in final edited form as: Gastroenterology. 2012 Apr; 142(4): 844–854.e4. Published online 2012 Jan 4. doi: 10.1053/j.gastro.2011.12.041
PMCID:
PMC3477545
AbstractArticlePDF–1.9M
17.
Effect of Five Genetic Variants Associated with Lung Function on the Risk of Chronic Obstructive Lung Disease, and Their Joint Effects on Lung Function
María Soler Artigas, Louise V. Wain, Emmanouela Repapi, Ma'en Obeidat, Ian Sayers, Paul R. Burton, Toby Johnson, Jing Hua Zhao, Eva Albrecht, Anna F. Dominiczak, Shona M. Kerr, Blair H. Smith, Gemma Cadby, Jennie Hui, Lyle J. Palmer, Aroon D. Hingorani, S. Goya Wannamethee, Peter H. Whincup, Shah Ebrahim, George Davey Smith, Inês Barroso, Ruth J. F. Loos, Nicholas J. Wareham, Cyrus Cooper, Elaine Dennison, Seif O. Shaheen, Jason Z. Liu, Jonathan Marchini, Santosh Dahgam, Åsa Torinsson Naluai, Anna-Carin Olin, Stefan Karrasch, Joachim Heinrich, Holger Schulz, Tricia M. McKeever, Ian D. Pavord, Markku Heliövaara, Samuli Ripatti, Ida Surakka, John D. Blakey, Mika Kähönen, John R. Britton, Fredrik Nyberg, John W. Holloway, Debbie A. Lawlor, Richard W. Morris, Alan L. James, Cathy M. Jackson, Ian P. Hall, Martin D. Tobin, Medical Research Council National Survey of Health and Development (NSHD) Respiratory Study Team, the SpiroMeta Consortium
Am J Respir Crit Care Med. 2011 Oct 1; 184(7): 786–795. Published online 2011 Oct 1. doi: 10.1164/rccm.201102-0192OC
PMCID:
PMC3398416
AbstractArticlePDF–584K
18.
Genome-wide Association Study of Periodontal Pathogen Colonization
K. Divaris, K.L. Monda, K.E. North, A.F. Olshan, E.M. Lange, K. Moss, S.P. Barros, J.D. Beck, S. Offenbacher
J Dent Res. 2012 Jul; 91(7 Suppl): S21–S28. doi: 10.1177/0022034512447951
PMCID:
PMC3383103
AbstractArticlePDF–2.0M
19.
Post–translational Modifications of Serotonin Type 4 Receptor Heterologously Expressed in Mouse Rod Cells
David Salom, Benlian Wang, Zhiqian Dong, Wenyu Sun, Pius Padayatti, Steven Jordan, John A. Salon, Krzysztof Palczewski
Biochemistry. Author manuscript; available in PMC 2013 Jan 10.
Published in final edited form as: Biochemistry. 2012 Jan 10; 51(1): 214–224. Published online 2011 Dec 20. doi: 10.1021/bi201707v
PMCID:
PMC3268512
AbstractArticlePDF–1.1M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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