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Items: 1 to 20 of 117

1.
Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk
Naomi Wilcox, Martine Dumont, Anna González-Neira, Sara Carvalho, Charles Joly Beauparlant, Marco Crotti, Craig Luccarini, Penny Soucy, Stéphane Dubois, Rocio Nuñez-Torres, Guillermo Pita, Eugene J. Gardner, Joe Dennis, M. Rosario Alonso, Nuria Álvarez, Caroline Baynes, Annie Claude Collin-Deschesnes, Sylvie Desjardins, Heiko Becher, Sabine Behrens, Manjeet K. Bolla, Jose E. Castelao, Jenny Chang-Claude, Sten Cornelissen, Thilo Dörk, Christoph Engel, Manuela Gago-Dominguez, Pascal Guénel, Andreas Hadjisavvas, Eric Hahnen, Mikael Hartman, Belén Herráez, SGBCC Investigators, Audrey Jung, Renske Keeman, Marion Kiechle, Jingmei Li, Maria A. Loizidou, Michael Lush, Kyriaki Michailidou, Mihalis I. Panayiotidis, Xueling Sim, Soo Hwang Teo, Jonathan P. Tyrer, Lizet E. van der Kolk, Cecilia Wahlström, Qin Wang, John R. B. Perry, Javier Benitez, Marjanka K. Schmidt, Rita K. Schmutzler, Paul D. P. Pharoah, Arnaud Droit, Alison M. Dunning, Anders Kvist, Peter Devilee, Douglas F. Easton, Jacques Simard
Nat Genet. 2023; 55(9): 1435–1439. Published online 2023 Aug 17. doi: 10.1038/s41588-023-01466-z
Correction in:
Nat Genet. 2023; 55(11): 2009.
PMCID:
PMC10484782
AbstractArticlePDF–3.5M
2.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
3.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
4.
MAP3K1 rs889312 polymorphism and cancer prognosis: A systematic review and meta‐analysis
Md. Abdul Aziz, Mohammad Safiqul Islam
Cancer Rep (Hoboken) 2023 Jan; 6(1): e1773. Published online 2022 Dec 22. doi: 10.1002/cnr2.1773
PMCID:
PMC9875638
AbstractArticlePDF–1.6M
5.
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation
Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang
Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005
PMCID:
PMC9772558
AbstractArticlePDF–8.2M
6.
Sex-dependent associations between MAP3K1 gene polymorphisms and soy products with the gastric cancer risk in Korea: a case-control study
Jung Hyun Kwak, Chang Soo Eun, Dong Soo Han, Yong Sung Kim, Kyu Sang Song, Bo Youl Choi, Hyun Ja Kim
BMC Gastroenterol. 2022; 22: 513. Published online 2022 Dec 12. doi: 10.1186/s12876-022-02569-3
PMCID:
PMC9743679
AbstractArticlePDF–855K
7.
Identification of a novel MAP3K1 variant in a family with 46, XY DSD and partial growth hormone deficiency
Yiping Cheng, Chao Xu, Jiangfei Yang, Xinli Zhou, Nan Chen
Mol Med Rep. 2022 Nov; 26(5): 338. Published online 2022 Sep 13. doi: 10.3892/mmr.2022.12854
PMCID:
PMC9494616
AbstractArticlePDF–1.2M
8.
The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis
Natalie Vaughan, Nico Scholz, Catherine Lindon, Julien D. F. Licchesi
Sci Rep. 2022; 12: 13160. Published online 2022 Aug 1. doi: 10.1038/s41598-022-16965-y
PMCID:
PMC9343455
AbstractArticlePDF–3.7M
9.
MicroRNA‐203a‐3p may prevent the development of thyroid papillary carcinoma via repressing MAP3K1 and activating autophagy
Lei Dai, Weidong Zhang, Xianjiang Wu, Shuihong Zhou
J Clin Lab Anal. 2022 Jun; 36(6): e24470. Published online 2022 May 6. doi: 10.1002/jcla.24470
PMCID:
PMC9169216
AbstractArticlePDF–4.2M
10.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
11.
MAP3K1 Variant Causes Hyperactivation of Wnt4/β-Catenin/FOXL2 Signaling Contributing to 46,XY Disorders/Differences of Sex Development
Hong Chen, Qingqing Chen, Yilin Zhu, Ke Yuan, Huizhu Li, Bingtao Zhang, Zexiao Jia, Hui Zhou, Mingjie Fan, Yue Qiu, Qianqian Zhuang, Zhaoying Lei, Mengyao Li, Wendong Huang, Li Liang, Qingfeng Yan, Chunlin Wang
Front Genet. 2022; 13: 736988. Published online 2022 Mar 3. doi: 10.3389/fgene.2022.736988
PMCID:
PMC8927045
AbstractArticlePDF–3.8M
12.
Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome
Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584
PMCID:
PMC8769072
AbstractArticlePDF–2.9M
13.
MEKK1-Dependent Activation of the CRL4 Complex Is Important for DNA Damage-Induced Degradation of p21 and DDB2 and Cell Survival
Susanne Bacher, Hilda Stekman, Carla M. Farah, Annika Karger, Michael Kracht, M. Lienhard Schmitz
Mol Cell Biol. 2021 Oct; 41(10): e00081-21. Prepublished online 2021 Jul 12. Published online 2021 Sep 24. doi: 10.1128/MCB.00081-21
PMCID:
PMC8462458
AbstractArticlePDF–3.1M
14.
LncRNA KCNQ1OT1 activated by c-Myc promotes cell proliferation via interacting with FUS to stabilize MAP3K1 in acute promyelocytic leukemia
Doudou Tang, Yujiao Luo, Yafeng Jiang, Piao Hu, Hongling Peng, Shangjie Wu, Guangsen Zhang, Yewei Wang
Cell Death Dis. 2021 Sep; 12(9): 795. Published online 2021 Aug 17. doi: 10.1038/s41419-021-04080-1
PMCID:
PMC8371007
AbstractArticlePDF–2.2M
15.
RNA-binding protein IMP3 is a novel regulator of MEK1/ERK signaling pathway in the progression of colorectal Cancer through the stabilization of MEKK1 mRNA
Meng Zhang, Senlin Zhao, Cong Tan, Yanzi Gu, Xuefeng He, Xiang Du, Dawei Li, Ping Wei
J Exp Clin Cancer Res. 2021; 40: 200. Published online 2021 Jun 21. doi: 10.1186/s13046-021-01994-8
PMCID:
PMC8215736
AbstractArticlePDF–5.4M
16.
Characteristics and possible mechanisms of 46, XY differences in sex development caused by novel compound variants in NR5A1 and MAP3K1
Yiping Cheng, Jing Chen, Xinli Zhou, Jiangfei Yang, Yiming Ji, Chao Xu
Orphanet J Rare Dis. 2021; 16: 268. Published online 2021 Jun 10. doi: 10.1186/s13023-021-01908-z
PMCID:
PMC8194036
AbstractArticlePDF–6.9M
17.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
18.
A novel missense heterozygous mutation in MAP3K1 gene causes 46, XY disorder of sex development: case report and literature review
Aisha Al Shamsi, Noura Al Hassani, Moustafa Hamchou, Raya Almazrouei, Aziz Mhanni
Mol Genet Genomic Med. 2020 Nov; 8(11): e1514. Published online 2020 Sep 28. doi: 10.1002/mgg3.1514
PMCID:
PMC7667354
AbstractArticlePDF–551K
19.
Nonsense-associated altered splicing of MAP3K1 in two siblings with 46,XY disorders of sex development
Maki Igarashi, Yohei Masunaga, Yuichi Hasegawa, Kenichi Kinjo, Mami Miyado, Hirotomo Saitsu, Yuko Kato-Fukui, Reiko Horikawa, Yomiko Okubo, Tsutomu Ogata, Maki Fukami
Sci Rep. 2020; 10: 17375. Published online 2020 Oct 15. doi: 10.1038/s41598-020-74405-1
PMCID:
PMC7567082
AbstractArticlePDF–1.1M
20.
A cryptic tubulin-binding domain links MEKK1 to curved tubulin protomers
Pavel Filipčík, Sharissa L. Latham, Antonia L. Cadell, Catherine L. Day, David R. Croucher, Peter D. Mace
Proc Natl Acad Sci U S A. 2020 Sep 1; 117(35): 21308–21318. Published online 2020 Aug 17. doi: 10.1073/pnas.2006429117
PMCID:
PMC7474687
AbstractArticlePDF–2.8M

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