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Items: 1 to 20 of 206

1.
The role of transcription factor FOXA1/C2/M1/O3/P1/Q1 in breast cancer
Hui Yuan, Yu Liang, Shaorun Hu, Jinxiang Chen, Jingcan You, Jun Jiang, Mao Luo, Min Zeng
Medicine (Baltimore) 2024 Apr 12; 103(15): e37709. Published online 2024 Apr 12. doi: 10.1097/MD.0000000000037709
PMCID:
PMC11018205
AbstractArticlePDF–3.3M
2.
Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer
Kevin J. Tam, Liangliang Liu, Michael Hsing, Kush Dalal, Daksh Thaper, Brian McConeghy, Parvin Yenki, Satyam Bhasin, James W. Peacock, Yuzhuo Wang, Artem Cherkasov, Paul S. Rennie, Martin E. Gleave, Christopher J. Ong
Sci Rep. 2024; 14: 7082. Published online 2024 Mar 25. doi: 10.1038/s41598-024-57854-w
PMCID:
PMC10963789
AbstractArticlePDF–4.5M
3.
Chromatin accessibility and pioneer factor FOXA1 restrict glucocorticoid receptor action in prostate cancer
Laura Helminen, Jasmin Huttunen, Melina Tulonen, Niina Aaltonen, Einari A Niskanen, Jorma J Palvimo, Ville Paakinaho
Nucleic Acids Res. 2024 Jan 25; 52(2): 625–642. Published online 2023 Nov 28. doi: 10.1093/nar/gkad1126
PMCID:
PMC10810216
AbstractArticlePDF–3.2M
4.
Lysosome‐dependent FOXA1 ubiquitination contributes to luminal lineage of advanced prostate cancer
Sherly I. Celada, Guoliang Li, Lindsay J. Celada, Wenfu Lu, Thanigaivelan Kanagasabai, Weiran Feng, Zhen Cao, Nazifa Salsabeel, Ninghui Mao, LaKendria K. Brown, Zaniya A. Mark, Michael G. Izban, Billy R. Ballard, Xinchun Zhou, Samuel E. Adunyah, Robert J. Matusik, Xiaofei Wang, Zhenbang Chen
Mol Oncol. 2023 Oct; 17(10): 2126–2146. Published online 2023 Aug 21. doi: 10.1002/1878-0261.13497
PMCID:
PMC10552895
AbstractArticlePDF–3.3M
5.
Hepatocyte-specific HDAC3 ablation promotes hepatocellular carcinoma in females by suppressing Foxa1/2
Yahong Xu, Yongjie Zhu, Zhenru Wu, Shengfu Li, Mingyang Shao, Qing Tao, Qing Xu, Yuwei Chen, Yuke Shu, Menglin Chen, Yongjie Zhou, Yujun Shi
BMC Cancer. 2023; 23: 906. Published online 2023 Sep 26. doi: 10.1186/s12885-023-11393-1
PMCID:
PMC10521566
AbstractArticlePDF–11M
6.
A Druggable FOXA1-Glucocorticoid Receptor Transcriptional Axis Drives Tumor Growth in a Subset of Non-Small Cell Lung Cancer
M. Dorso, Payal T. Patel, Aleksandr Pankov, Jacob A. Boyer, Rajesh K. Soni, Isabella S. Del Priore, Omar Hayatt, Amanda Kulick, Connor J. Hagen, Elisa de Stanchina, Melissa R. Junttila, Anneleen Daemen, Lori S. Friedman, Ronald C. Hendrickson, Sarat Chandarlapaty
Cancer Res Commun. 2023 Sep; 3(9): 1788–1799. Published online 2023 Sep 7. doi: 10.1158/2767-9764.CRC-23-0310
PMCID:
PMC10484118
AbstractArticlePDF–9.6M
7.
SETD7 functions as a transcription repressor in prostate cancer via methylating FOXA1
Zifeng Wang, Jessica Petricca, Mingyu Liu, Songqi Zhang, Sujun Chen, Muqing Li, Anna Besschetnova, Susan Patalano, Kavita Venkataramani, Kellee R. Siegfried, Jill A. Macoska, Dong Han, Shuai Gao, Masoud Vedadi, Cheryl H. Arrowsmith, Housheng Hansen He, Changmeng Cai
Proc Natl Acad Sci U S A. 2023 Aug 15; 120(33): e2220472120. Published online 2023 Aug 7. doi: 10.1073/pnas.2220472120
PMCID:
PMC10438836
AbstractArticlePDF–7.2M
8.
FOXA1 O-GlcNAcylation–mediated transcriptional switch governs metastasis capacity in breast cancer
Yajie Liu, Kairan Yu, Xiaotian Kong, Keren Zhang, Lingyan Wang, Nana Zhang, Qiushi Chen, Mingshan Niu, Wenli Li, Xiaomin Zhong, Sijin Wu, Jianing Zhang, Yubo Liu
Sci Adv. 2023 Aug; 9(33): eadg7112. Published online 2023 Aug 18. doi: 10.1126/sciadv.adg7112
PMCID:
PMC10438466
AbstractArticlePDF–3.9M
9.
Association of Double-Positive FOXA1 and FOXP1 Immunoreactivities with Favorable Prognosis of Tamoxifen-Treated Breast Cancer Patients
Nobuhiro Ijichi, Takashi Shigekawa, Kazuhiro Ikeda, Kuniko Horie-Inoue, Chikako Shimizu, Shigehira Saji, Kenjiro Aogi, Hitoshi Tsuda, Akihiko Osaki, Toshiaki Saeki, Satoshi Inoue
Horm Cancer. 2012 Aug; 3(4): 147–159. Published online 2012 Apr 3. doi: 10.1007/s12672-012-0111-0
PMCID:
PMC10358124
AbstractArticlePDF–502K
10.
FOXA1 reprogramming dictates retinoid X receptor response in ESR1 mutant breast cancer
Yang Wu, Zheqi Li, Abdalla M. Wedn, Allison N. Casey, Daniel Brown, Shalini V. Rao, Soleilmane Omarjee, Jagmohan Hooda, Jason S. Carroll, Jason Gertz, Jennifer M. Atkinson, Adrian V. Lee, Steffi Oesterreich
Mol Cancer Res. Author manuscript; available in PMC 2023 Dec 1.
Published in final edited form as: Mol Cancer Res. 2023 Jun 1; 21(6): 591–604. doi: 10.1158/1541-7786.MCR-22-0516
PMCID:
PMC10239325
AbstractArticlePDF–2.4M
11.
FOXA1 in prostate cancer
Hui-Yu Dong, Lei Ding, Tian-Ren Zhou, Tao Yan, Jie Li, Chao Liang
Asian J Androl. 2023 May-Jun; 25(3): 287–295. Published online 2022 Aug 19. doi: 10.4103/aja202259
PMCID:
PMC10226509
AbstractArticlePDF–986K
12.
TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis
Lindsey J. Anstine, Parth R. Majmudar, Amy Aponte, Salendra Singh, Ran Zhao, Kristen L. Weber-Bonk, Fadi W. Abdul-Karim, Mitchell Valentine, Darcie D. Seachrist, Katelyn E. Grennel-Nickelson, Leslie Cuellar-Vite, Gina M. Sizemore, Steven T. Sizemore, Bryan M. Webb, Cheryl L. Thompson, Ruth A. Keri
Cancer Res. Author manuscript; available in PMC 2023 Oct 4.
Published in final edited form as: Cancer Res. 2023 Apr 4; 83(7): 997–1015. doi: 10.1158/0008-5472.CAN-22-3133
PMCID:
PMC10089698
AbstractArticlePDF–2.2M
13.
Expression of FOXA1 Is Associated with the Tumor-Infiltrating M2 Macrophage, Cytotoxic T Lymphocyte, and Effect of Chemotherapy in Bladder Cancer
Yiduo Wang, Huan Qu, Bin Xu, Jianping Wu, Kai Lu, Chunhui Liu, Shuqiu Chen, Ming Chen
Urol Int. 2023 Jan; 107(1): 58–63. Published online 2021 Oct 27. doi: 10.1159/000519129
PMCID:
PMC9909707
AbstractArticle
14.
Estrogen receptor α K303R mutation reorganizes its binding to forkhead box protein A1 regions and induces chromatin opening
Tomoyoshi Nakadai, Liying Yang, Kohei Kumegawa, Reo Maruyama
Mol Biol Rep. 2023; 50(2): 1209–1220. Published online 2022 Nov 27. doi: 10.1007/s11033-022-08089-3
PMCID:
PMC9889408
AbstractArticlePDF–2.3M
15.
FOXA1 repression drives lineage plasticity and immune heterogeneity in bladder cancers with squamous differentiation
Joshua I. Warrick, Wenhuo Hu, Hironobu Yamashita, Vonn Walter, Lauren Shuman, Jenna M. Craig, Lan L. Gellert, Mauro A. A. Castro, A. Gordon Robertson, Fengshen Kuo, Irina Ostrovnaya, Judy Sarungbam, Ying-bei Chen, Anuradha Gopalan, Sahussapont J. Sirintrapun, Samson W. Fine, Satish K. Tickoo, Kwanghee Kim, Jasmine Thomas, Nagar Karan, Sizhi Paul Gao, Timothy N. Clinton, Andrew T. Lenis, Timothy A. Chan, Ziyu Chen, Manisha Rao, Travis J. Hollman, Yanyun Li, Nicholas D. Socci, Shweta Chavan, Agnes Viale, Neeman Mohibullah, Bernard H. Bochner, Eugene J. Pietzak, Min Yuen Teo, Gopa Iyer, Jonathan E. Rosenberg, Dean F. Bajorin, Matthew Kaag, Suzanne B. Merrill, Monika Joshi, Rosalyn Adam, John A. Taylor, III, Peter E. Clark, Jay D. Raman, Victor E. Reuter, Yu Chen, Samuel A. Funt, David B. Solit, David J. DeGraff, Hikmat A. Al-Ahmadie
Nat Commun. 2022; 13: 6575. Published online 2022 Nov 2. doi: 10.1038/s41467-022-34251-3
Correction in:
Nat Commun. 2022; 13: 7920.
PMCID:
PMC9630410
AbstractArticlePDF–3.5M
16.
FOXA1 regulates alternative splicing in prostate cancer
Marco Del Giudice, John G. Foster, Serena Peirone, Alberto Rissone, Livia Caizzi, Federica Gaudino, Caterina Parlato, Francesca Anselmi, Rebecca Arkell, Simonetta Guarrera, Salvatore Oliviero, Giuseppe Basso, Prabhakar Rajan, Matteo Cereda
Cell Rep. 2022 Sep 27; 40(13): 111404. Published online 2022 Sep 27. doi: 10.1016/j.celrep.2022.111404
PMCID:
PMC9532847
AbstractArticle
17.
FOXA1 inhibits hypoxia programs through transcriptional repression of HIF1A
Xiaohai Wang, Lourdes Brea, Xiaodong Lu, Galina Gritsina, Su H. Park, Wanqing Xie, Jonathan C. Zhao, Jindan Yu
Oncogene. Author manuscript; available in PMC 2023 Mar 1.
Published in final edited form as: Oncogene. 2022 Aug 5 : 10.1038/s41388-022-02423-6. Published online 2022 Aug 5. doi: 10.1038/s41388-022-02423-6
PMCID:
PMC9464719
AbstractArticlePDF–1.9M
18.
Knockdown of FOXA1 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the ERK1/2 signalling pathway
Lijun Li, Yibo Wang, Zhongxiang Wang, Deting Xue, Chengxin Dai, Xiang Gao, Jianfei Ma, Kai Hang, Zhijun Pan
Stem Cell Res Ther. 2022; 13: 456. Published online 2022 Sep 5. doi: 10.1186/s13287-022-03133-2
PMCID:
PMC9446550
AbstractArticlePDF–8.6M
19.
FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations
Yuri Choi, Yongyang Luo, Seunghwa Lee, Hanyong Jin, Hye-Jin Yoon, Yoonsoo Hahn, Jeehyeon Bae, Hyung Ho Lee
Nucleic Acids Res. 2022 Aug 26; 50(15): 8929–8946. Published online 2022 Aug 3. doi: 10.1093/nar/gkac673
PMCID:
PMC9410875
AbstractArticlePDF–5.3M
20.
FOXA1 prevents nutrients deprivation induced autophagic cell death through inducing loss of imprinting of IGF2 in lung adenocarcinoma
Junjun Li, Yongchang Zhang, Li Wang, Min Li, Jianbo Yang, Pan Chen, Jie Zhu, Xiayu Li, Zhaoyang Zeng, Guiyuan Li, Wei Xiong, James B. McCarthy, Bo Xiang, Mei Yi
Cell Death Dis. 2022 Aug; 13(8): 711. Published online 2022 Aug 16. doi: 10.1038/s41419-022-05150-8
PMCID:
PMC9381574
AbstractArticlePDF–12M

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