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Select item 111138061.

Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1

Wei Wang, Jinyang Cai, Yingliang Wu, Li Hu, Zongyun Chen, Jun Hu, Ze Chen, Wenxin Li, Mingxiong Guo, Zan Huang

Cell Mol Life Sci. 2013 Oct; 70(20): 3947–3958. Published online 2013 May 12. doi: 10.1007/s00018-013-1359-4

PMCID:: PMC11113806

Abstract Article PDF–2.3M

Select item 106959272.

HECW1 induces NCOA4-regulated ferroptosis in glioma through the ubiquitination and degradation of ZNF350

Yuancai Lin, Hailong Gong, Jinliang Liu, Zhiwen Hu, Mingjun Gao, Wei Yu, Jing Liu

Cell Death Dis. 2023 Dec; 14(12): 794. Published online 2023 Dec 4. doi: 10.1038/s41419-023-06322-w

PMCID:: PMC10695927

Abstract Article PDF–5.9M

Select item 98036783.

DYRK3 phosphorylates SNAPIN to regulate axonal retrograde transport and neurotransmitter release

Ye Hyung Lee, Bo Kyoung Suh, Unghwi Lee, Seung Hyun Ryu, Sung Ryong Shin, Sunghoe Chang, Sang Ki Park, Kwang Chul Chung

Cell Death Discov. 2022; 8: 503. Published online 2022 Dec 30. doi: 10.1038/s41420-022-01290-0

PMCID:: PMC9803678

Abstract Article PDF–3.4M

Select item 93485764.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 91052355.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 85341236.

Role of the Transcriptional Repressor Zinc Finger with KRAB and SCAN Domains 3 (ZKSCAN3) in Retinal Pigment Epithelial Cells

Hsuan-Yeh Pan, Mallika Valapala

Cells. 2021 Oct; 10(10): 2504. Published online 2021 Sep 22. doi: 10.3390/cells10102504

PMCID:: PMC8534123

Abstract Article PDF–4.2M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77889628.

Correlation between ZBRK1/ZNF350 gene polymorphism and breast cancer

Jun Wu, Alibiati Eni, Eliar Roussuri, Binlin Ma

BMC Med Genomics. 2021; 14: 7. Published online 2021 Jan 6. doi: 10.1186/s12920-020-00862-2

PMCID:: PMC7788962

Abstract Article PDF–856K

Select item 73200439.

Fbxl17 is rearranged in breast cancer and loss of its activity leads to increased global O-GlcNAcylation

Bethany Mason, Susanne Flach, Felipe R. Teixeira, Raquel Manzano Garcia, Oscar M. Rueda, Jean E. Abraham, Carlos Caldas, Paul A. W. Edwards, Heike Laman

Cell Mol Life Sci. 2020 Jul; 77(13): 2605–2620. Published online 2019 Sep 27. doi: 10.1007/s00018-019-03306-y

PMCID:: PMC7320043

Abstract Article PDF–2.5M

Select item 725971110.

PFKP is transcriptionally repressed by BRCA1/ZBRK1 and predicts prognosis in breast cancer

Danna Yeerken, Ruoxi Hong, Yan Wang, Ying Gong, Rui Liu, Di Yang, Jinting Li, Jiawen Fan, Jie Chen, Weimin Zhang, Qimin Zhan

PLoS One. 2020; 15(5): e0233750. Published online 2020 May 29. doi: 10.1371/journal.pone.0233750

PMCID:: PMC7259711

Abstract Article PDF–2.9M

Select item 666077211.

Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing

Guido A. Stoll, Shun-ichiro Oda, Zheng-Shan Chong, Minmin Yu, Stephen H. McLaughlin, Yorgo Modis

Proc Natl Acad Sci U S A. 2019 Jul 23; 116(30): 15042–15051. Published online 2019 Jul 9. doi: 10.1073/pnas.1901318116

PMCID:: PMC6660772

Abstract Article PDF–2.3M

Select item 644189512.

Preventing BRCA1/ZBRK1 repressor complex binding to the GOT2 promoter results in accelerated aspartate biosynthesis and promotion of cell proliferation

Ruoxi Hong, Weimin Zhang, Xi Xia, Kai Zhang, Yan Wang, Mengjiao Wu, Jiawen Fan, Jinting Li, Wen Xia, Fei Xu, Jie Chen, Shusen Wang, Qimin Zhan

Mol Oncol. 2019 Apr; 13(4): 959–977. Published online 2019 Mar 1. doi: 10.1002/1878-0261.12466

Correction in:: Mol Oncol. 2020 Oct; 14(10): 2696.

PMCID:: PMC6441895

Abstract Article PDF–2.6M

Select item 617246913.

KAP1 regulates endogenous retroviruses in adult human cells and contributes to innate immune control

Christopher HC Tie, Liane Fernandes, Lucia Conde, Luisa Robbez‐Masson, Rebecca P Sumner, Tom Peacock, Maria Teresa Rodriguez‐Plata, Greta Mickute, Robert Gifford, Greg J Towers, Javier Herrero, Helen M Rowe

EMBO Rep. 2018 Oct; 19(10): e45000. Published online 2018 Jul 30. doi: 10.15252/embr.201745000

PMCID:: PMC6172469

Abstract Article PDF–848K

Select item 615842814.

Human Cytomegalovirus UL135 Interacts with Host Adaptor Proteins To Regulate Epidermal Growth Factor Receptor and Reactivation from Latency

Michael A. Rak, Jason Buehler, Sebastian Zeltzer, Justin Reitsma, Belen Molina, Scott Terhune, Felicia Goodrum

J Virol. 2018 Oct 15; 92(20): e00919-18. Prepublished online 2018 Aug 8. Published online 2018 Sep 26. doi: 10.1128/JVI.00919-18

Correction in:: J Virol. 2020 Apr; 94(7): e00748-19.

PMCID:: PMC6158428

Abstract Article PDF–759K

Select item 511720415.

The centrosomal deubiquitylase USP21 regulates Gli1 transcriptional activity and stability

Claire Heride, Daniel J. Rigden, Erithelgi Bertsoulaki, Danilo Cucchi, Enrico De Smaele, Michael J. Clague, Sylvie Urbé

J Cell Sci. 2016 Nov 1; 129(21): 4001–4013. doi: 10.1242/jcs.188516

PMCID:: PMC5117204

Abstract Article

Select item 475160316.

By moonlighting in the nucleus, villin regulates epithelial plasticity

Srinivas Patnaik, Sudeep P. George, Eric Pham, Swati Roy, Kanchan Singh, John M. Mariadason, Seema Khurana

Mol Biol Cell. 2016 Feb 1; 27(3): 535–548. doi: 10.1091/mbc.E15-06-0453

PMCID:: PMC4751603

Abstract Article PDF–4.1M

Select item 446666217.

ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer

Ke Chen, Gan Yu, Kiranmai Gumireddy, Anping Li, Weimin Yao, Lu Gao, Shuliang Chen, Jun Hao, Ji Wang, Qihong Huang, Hua Xu, Zhangqun Ye

Oncotarget. 2015 Mar 30; 6(9): 6959–6976. Published online 2015 Feb 10. doi: 10.18632/oncotarget.3134

PMCID:: PMC4466662

Abstract Article PDF–11M

Select item 422155218.

MAGE proteins regulate KRAB zinc finger transcription factors and KAP1 E3 ligase activity

Tony Z Xiao, Yewseok Suh, B Jack Longley

Arch Biochem Biophys. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: Arch Biochem Biophys. 2014 Dec 1; 563: 136–144. Published online 2014 Aug 7. doi: 10.1016/j.abb.2014.07.026

PMCID:: PMC4221552

Abstract Article PDF–3.3M

Select item 374999619.

Loss of ZBRK1 Contributes to the Increase of KAP1 and Promotes KAP1-Mediated Metastasis and Invasion in Cervical Cancer

Li-Fang Lin, Chien-Feng Li, Wei-Jan Wang, Wen-Ming Yang, Dennis Ding-Hwa Wang, Wen-Chang Chang, Wen-Hwa Lee, Ju-Ming Wang

PLoS One. 2013; 8(8): e73033. Published online 2013 Aug 22. doi: 10.1371/journal.pone.0073033

PMCID:: PMC3749996

Abstract Article PDF–2.6M

Select item 323711420.

ZBRK1 acts as a metastatic suppressor by directly regulating MMP9 in cervical cancer

Li-Fang Lin, Chih-Hung Chuang, Chien-Feng Li, Ching-Chun Liao, Chun-Pei Cheng, Tian-Lu Cheng, Meng-Ru Shen, Joseph T. Tseng, Wen-Chang Chang, Wen-Hwa Lee, Ju-Ming Wang

Cancer Res. Author manuscript; available in PMC 2011 Dec 14.

Published in final edited form as: Cancer Res. 2010 Jan 1; 70(1): 192–201. Published online 2009 Dec 8. doi: 10.1158/0008-5472.CAN-09-2641

PMCID:: PMC3237114

Abstract Article PDF–1.9M

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