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Select item 111586861.

Frequent silencing of a putative tumor suppressor gene melatonin receptor 1 A (MTNR1A) in oral squamous‐cell carcinoma

Erina Nakamura, Ken‐ichi Kozaki, Hitoshi Tsuda, Emina Suzuki, Atiphan Pimkhaokham, Gou Yamamoto, Tarou Irie, Tetsuhiko Tachikawa, Teruo Amagasa, Johji Inazawa, Issei Imoto

Cancer Sci. 2008 Jul; 99(7): 1390–1400. Published online 2008 Apr 30. doi: 10.1111/j.1349-7006.2008.00838.x

PMCID:: PMC11158686

Abstract Article PDF–316K

Select item 109729582.

Rs4862705 in the melatonin receptor 1A gene is associated with renal function decline in type 1 diabetes individuals

Gustavo Daher, Daniele Pereira Santos-Bezerra, Ana Mercedes Cavaleiro, Tatiana Souza Pelaes, Sharon Nina Admoni, Ricardo Vessoni Perez, Cleide Guimarães Machado, Fernanda Gaspar do Amaral, José Cipolla-Neto, Maria Lúcia Correa-Giannella

Front Endocrinol (Lausanne) 2024; 15: 1331012. Published online 2024 Mar 14. doi: 10.3389/fendo.2024.1331012

PMCID:: PMC10972958

Abstract Article PDF–499K

Select item 101579913.

Association of rotating night shift work, CLOCK, MTNR1A, MTNR1B genes polymorphisms and their interactions with type 2 diabetes among steelworkers: a case–control study

Qinglin Li, Shengkui Zhang, Han Wang, Zhende Wang, Xiaohong Zhang, Yongbin Wang, Juxiang Yuan

BMC Genomics. 2023; 24: 232. Published online 2023 May 3. doi: 10.1186/s12864-023-09328-y

PMCID:: PMC10157991

Abstract Article PDF–1.1M

Select item 100339374.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 93217705.

Melatonin Reverses the Warburg-Type Metabolism and Reduces Mitochondrial Membrane Potential of Ovarian Cancer Cells Independent of MT1 Receptor Activation

Maira Smaniotto Cucielo, Roberta Carvalho Cesário, Henrique Spaulonci Silveira, Letícia Barbosa Gaiotte, Sérgio Alexandre Alcantara dos Santos, Debora Aparecida Pires de Campos Zuccari, Fábio Rodrigues Ferreira Seiva, Russel J. Reiter, Luiz Gustavo de Almeida Chuffa

Molecules. 2022 Jul; 27(14): 4350. Published online 2022 Jul 7. doi: 10.3390/molecules27144350

PMCID:: PMC9321770

Abstract Article PDF–4.8M

Select item 87869396.

Structural basis of the ligand binding and signaling mechanism of melatonin receptors

Qinggong Wang, Qiuyuan Lu, Qiong Guo, Maikun Teng, Qingguo Gong, Xu Li, Yang Du, Zheng Liu, Yuyong Tao

Nat Commun. 2022; 13: 454. Published online 2022 Jan 24. doi: 10.1038/s41467-022-28111-3

PMCID:: PMC8786939

Abstract Article PDF–2.1M

Select item 71699837.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 70165948.

Expression of Melatonin and Dopamine D₃ Receptor Heteromers in Eye Ciliary Body Epithelial Cells and Negative Correlation with Ocular Hypertension

Irene Reyes-Resina, Hanan Awad Alkozi, Anna del Ser-Badia, Juan Sánchez-Naves, Jaume Lillo, Jasmina Jiménez, Jesús Pintor, Gemma Navarro, Rafael Franco

Cells. 2020 Jan; 9(1): 152. Published online 2020 Jan 8. doi: 10.3390/cells9010152

PMCID:: PMC7016594

Abstract Article PDF–3.2M

Select item 69820649.

Age Associated Decrease of MT-1 Melatonin Receptor in Human Dermal Skin Fibroblasts Impairs Protection Against UV-Induced DNA Damage

Kelly Dong, Earl Goyarts, Antonella Rella, Edward Pelle, Yung Hou Wong, Nadine Pernodet

Int J Mol Sci. 2020 Jan; 21(1): 326. Published online 2020 Jan 3. doi: 10.3390/ijms21010326

PMCID:: PMC6982064

Abstract Article PDF–1.8M

Select item 669693810.

Structural basis for ligand recognition at the human MT₁ melatonin receptor

Benjamin Stauch, Linda C. Johansson, John D. McCorvy, Nilkanth Patel, Gye Won Han, Xi-Ping Huang, Cornelius Gati, Alexander Batyuk, Samuel T. Slocum, Andrii Ishchenko, Wolfgang Brehm, Thomas A. White, Nairie Michaelian, Caleb Madsen, Lan Zhu, Thomas D. Grant, Jessica M. Grandner, Anna Shiriaeva, Reid H.J. Olsen, Alexandra R. Tribo, Saïd Yous, Raymond C. Stevens, Uwe Weierstall, Vsevolod Katritch, Bryan L. Roth, Wei Liu, Vadim Cherezov

Nature. Author manuscript; available in PMC 2019 Oct 24.

Published in final edited form as: Nature. 2019 May; 569(7755): 284–288. Published online 2019 Apr 24. doi: 10.1038/s41586-019-1141-3

Correction in:: Nature. 2019 May 3

PMCID:: PMC6696938

Abstract Article PDF–2.8M

Select item 639003411.

Genetic polymorphisms of melatonin receptors 1A and 1B may result in disordered lipid metabolism in obese patients with polycystic ovary syndrome

Xiu-Hua Xu, Lian-Cui Kou, Hai-Mei Wang, Chun-Mei Bo, Xiao-Cui Song

Mol Med Rep. 2019 Mar; 19(3): 2220–2230. Published online 2019 Jan 17. doi: 10.3892/mmr.2019.9872

PMCID:: PMC6390034

Abstract Article PDF–1.0M

Select item 604743412.

Melatonin receptor type 1A gene linked to Alzheimer’s disease in old age

Sonja Sulkava, Pranuthi Muggalla, Raimo Sulkava, Hanna M Ollila, Terhi Peuralinna, Liisa Myllykangas, Karri Kaivola, David J Stone, Bryan J Traynor, Alan E Renton, Alberto M Rivera, Seppo Helisalmi, Hilkka Soininen, Tuomo Polvikoski, Mikko Hiltunen, Pentti J Tienari, Henri J Huttunen, Tiina Paunio

Sleep. 2018 Jul; 41(7): zsy103. Published online 2018 Jul 6. doi: 10.1093/sleep/zsy103

PMCID:: PMC6047434

Abstract Article PDF–1.4M

Select item 584351013.

Nocturnal activation of melatonin receptor type 1 signaling modulates diurnal insulin sensitivity via regulation of PI3K activity

Sharon Owino, Aida Sánchez-Bretaño, Cynthia Tchio, Erika Cecon, Angeliki Karamitri, Julie Dam, Ralf Jockers, Giuseppe Piccione, Hye Lim Noh, Taekyoon Kim, Jason K. Kim, Kenkichi Baba, Gianluca Tosini

J Pineal Res. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: J Pineal Res. 2018 Apr; 64(3): 10.1111/jpi.12462. Published online 2018 Jan 9. doi: 10.1111/jpi.12462

PMCID:: PMC5843510

Abstract Article PDF–2.6M

Select item 581246214.

Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies

A. Demirkan, J. Lahti, N. Direk, A. Viktorin, K. L. Lunetta, A. Terracciano, M. A. Nalls, T. Tanaka, K. Hek, M. Fornage, J. Wellmann, M. C. Cornelis, H. M. Ollila, L. Yu, J. A. Smith, L. C. Pilling, A. Isaacs, A. Palotie, W. V. Zhuang, A. Zonderman, J. D. Faul, A. Sutin, O. Meirelles, A. Mulas, A. Hofman, A. Uitterlinden, F. Rivadeneira, M. Perola, W. Zhao, V. Salomaa, K. Yaffe, A. I. Luik, NABEC, UKBEC, Y. Liu, J. Ding, P. Lichtenstein, M. Landén, E. Widen, D. R. Weir, D. J. Llewellyn, A. Murray, S. L. R. Kardia, J. G. Eriksson, K. Koenen, P. K. E. Magnusson, L. Ferrucci, T. H. Mosley, F. Cucca, B. A. Oostra, D. A. Bennett, T. Paunio, K. Berger, T. B. Harris, N. L. Pedersen, J. M. Murabito, H. Tiemeier, C. M. van Duijn, K. Räikkönen

Psychol Med. Author manuscript; available in PMC 2018 Feb 14.

Published in final edited form as: Psychol Med. 2016 Jun; 46(8): 1613–1623. Published online 2016 Mar 21. doi: 10.1017/S0033291715002081

PMCID:: PMC5812462

Abstract Article PDF–344K

Select item 580655715.

Common Genetic Variation Near Melatonin Receptor 1A Gene Linked to Job-Related Exhaustion in Shift Workers

Sonja Sulkava, Hanna M. Ollila, Jukka Alasaari, Sampsa Puttonen, Mikko Härmä, Katriina Viitasalo, Alexandra Lahtinen, Jaana Lindström, Auli Toivola, Raimo Sulkava, Mika Kivimäki, Jussi Vahtera, Timo Partonen, Kaisa Silander, Tarja Porkka-Heiskanen, Tiina Paunio

Sleep. 2017 Jan 1; 40(1): zsw011. Published online 2017 Feb 9. doi: 10.1093/sleep/zsw011

PMCID:: PMC5806557

Abstract Article PDF–683K

Select item 566654416.

Genetic Variations of Melatonin Receptor Type 1A are Associated with the Clinicopathologic Development of Urothelial Cell Carcinoma

Yung-Wei Lin, Shian-Shiang Wang, Yu-Ching Wen, Min-Che Tung, Liang-Ming Lee, Shun-Fa Yang, Ming-Hsien Chien

Int J Med Sci. 2017; 14(11): 1130–1135. Published online 2017 Sep 4. doi: 10.7150/ijms.20629

PMCID:: PMC5666544

Abstract Article PDF–300K

Select item 537173017.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 441685718.

Convergence of Melatonin and Serotonin (5-HT) Signaling at MT₂/5-HT_2C Receptor Heteromers

Maud Kamal, Florence Gbahou, Jean-Luc Guillaume, Avais M. Daulat, Abla Benleulmi-Chaachoua, Marine Luka, Patty Chen, Dina Kalbasi Anaraki, Marc Baroncini, Clotilde Mannoury la Cour, Mark J. Millan, Vincent Prevot, Philippe Delagrange, Ralf Jockers

J Biol Chem. 2015 May 1; 290(18): 11537–11546. Published online 2015 Mar 13. doi: 10.1074/jbc.M114.559542

PMCID:: PMC4416857

Abstract Article PDF–1.7M

Select item 437886019.

Human Gastroenteropancreatic Expression of Melatonin and Its Receptors MT1 and MT2

Fanny Söderquist, Per M. Hellström, Janet L. Cunningham

PLoS One. 2015; 10(3): e0120195. Published online 2015 Mar 30. doi: 10.1371/journal.pone.0120195

PMCID:: PMC4378860

Abstract Article PDF–2.2M

Select item 437372320.

Interactions between Environmental Factors and Melatonin Receptor Type 1A Polymorphism in Relation to Oral Cancer Susceptibility and Clinicopathologic Development

Feng-Yan Lin, Chiao-Wen Lin, Shun-Fa Yang, Wei-Jiunn Lee, Yung-Wei Lin, Liang-Ming Lee, Junn-Liang Chang, Wei-Chun Weng, Chien-Huang Lin, Ming-Hsien Chien

PLoS One. 2015; 10(3): e0121677. Published online 2015 Mar 25. doi: 10.1371/journal.pone.0121677

PMCID:: PMC4373723

Abstract Article PDF–385K

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