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Select item 111235711.

Exostoisns (EXT1/2) in Head and Neck Cancers: An In Silico Analysis and Clinical Correlates

Yiping Wang, Yan Huang, Houwei Zhu, Zhenzhen Guo, Jun Cheng, Churen Zhang, Ming Zhong

Int Dent J. 2024 Jun; 74(3): 446–453. Published online 2023 Nov 21. doi: 10.1016/j.identj.2023.10.017

PMCID:: PMC11123571

Abstract Article PDF–2.0M

Select item 111094832.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 101600063.

Structural basis for heparan sulfate co-polymerase action by the EXT1–2 complex

Hua Li, Digantkumar Chapla, Robert A. Amos, Annapoorani Ramiah, Kelley W. Moremen, Huilin Li

Nat Chem Biol. Author manuscript; available in PMC 2023 May 5.

Published in final edited form as: Nat Chem Biol. 2023 May; 19(5): 565–574. Published online 2023 Jan 2. doi: 10.1038/s41589-022-01220-2

PMCID:: PMC10160006

Abstract Article PDF–6.1M

Select item 99174514.

Insights into the Peritumoural Brain Zone of Glioblastoma: CDK4 and EXT2 May Be Potential Drivers of Malignancy

Martina Giambra, Andrea Di Cristofori, Donatella Conconi, Matilde Marzorati, Serena Redaelli, Melissa Zambuto, Alessandra Rocca, Louis Roumy, Giorgio Carrabba, Marialuisa Lavitrano, Gaia Roversi, Carlo Giussani, Angela Bentivegna

Int J Mol Sci. 2023 Feb; 24(3): 2835. Published online 2023 Feb 2. doi: 10.3390/ijms24032835

PMCID:: PMC9917451

Abstract Article PDF–6.8M

Select item 96757545.

Structure of the human heparan sulfate polymerase complex EXT1-EXT2

Francisco Leisico, Juneina Omeiri, Christine Le Narvor, Joël Beaudouin, Michael Hons, Daphna Fenel, Guy Schoehn, Yohann Couté, David Bonnaffé, Rabia Sadir, Hugues Lortat-Jacob, Rebekka Wild

Nat Commun. 2022; 13: 7110. Published online 2022 Nov 19. doi: 10.1038/s41467-022-34882-6

PMCID:: PMC9675754

Abstract Article PDF–2.4M

Select item 92316236.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 91714117.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 91322478.

A dominant negative splice variant of the heparan sulfate biosynthesis enzyme NDST1 reduces heparan sulfate sulfation

Parisa Missaghian, Tabea Dierker, Elham Khosrowabadi, Fredrik Axling, Inger Eriksson, Abdurrahman Ghanem, Marion Kusche-Gullberg, Sakari Kellokumpu, Lena Kjellén

Glycobiology. 2022 Jun; 32(6): 518–528. Published online 2022 Feb 7. doi: 10.1093/glycob/cwac004

PMCID:: PMC9132247

Abstract Article PDF–1.4M

Select item 91197369.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 905883610.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Abstract Article PDF–2.9M

Select item 891539811.

Clinical survey of a pedigree with hereditary multiple exostoses and identification of EXT-2 gene deletion mutation

Wentao Wang, Mingyuan Yang, Yuhang Shen, Kai Chen, Donghua Wu, Changwei Yang, Jinyi Bai, Dawei He, Jun Gao

Mol Med Rep. 2022 Apr; 25(4): 141. Published online 2022 Feb 24. doi: 10.3892/mmr.2022.12657

PMCID:: PMC8915398

Abstract Article PDF–1.5M

Select item 886447212.

Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network

Rebecca Elizabeth Kattan, Han Han, Gayoung Seo, Bing Yang, Yongqi Lin, Max Dotson, Stephanie Pham, Yahya Menely, Wenqi Wang

Mol Cell Proteomics. 2022 Feb; 21(2): 100195. Published online 2022 Jan 8. doi: 10.1016/j.mcpro.2022.100195

PMCID:: PMC8864472

Abstract Article PDF–3.6M

Select item 886400013.

Prevalence of neural epidermal growth factor-like 1- and exostosin 1/exostosin 2-associated membranous nephropathy: a single-center retrospective study in Japan

Takamasa Iwakura, Chiemi Ema, Shinsuke Isobe, Tomoyuki Fujikura, Naro Ohashi, Akihiko Kato, Hideo Yasuda

Sci Rep. 2022; 12: 2967. Published online 2022 Feb 22. doi: 10.1038/s41598-022-07037-2

PMCID:: PMC8864000

Abstract Article PDF–3.0M

Select item 851385314.

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation

Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari

PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412

PMCID:: PMC8513853

Abstract Article PDF–4.1M

Select item 841849915.

Identification of a novel EXT2 frameshift mutation in a family with hereditary multiple exostoses by whole‐exome sequencing

Mei Yang, Hanbing Xie, Bocheng Xu, Qinqin Xiang, He Wang, Ting Hu, Shanling Liu

J Clin Lab Anal. 2021 Sep; 35(9): e23968. Published online 2021 Aug 17. doi: 10.1002/jcla.23968

PMCID:: PMC8418499

Abstract Article PDF–1001K

Select item 816503016.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 792017717.

In Patients with Membranous Lupus Nephritis, Exostosin-Positivity and Exostosin-Negativity Represent Two Different Phenotypes

Aishwarya Ravindran, Marta Casal Moura, Fernando C. Fervenza, Samih H. Nasr, Mariam P. Alexander, Mary E. Fidler, Loren P. Herrera Hernandez, Pingchuan Zhang, Joseph P. Grande, Lynn D. Cornell, Lou Ann Gross, Vivian Negron, Grace E. Jenson, Benjamin J. Madden, M. Cristine Charlesworth, Sanjeev Sethi

J Am Soc Nephrol. 2021 Mar; 32(3): 695–706. Published online 2021 Jan 21. doi: 10.1681/ASN.2020081181

PMCID:: PMC7920177

Abstract Article

Select item 790591018.

Mutation spectrum of EXT1 and EXT2 in the Saudi patients with hereditary multiple exostoses

Zayed Al-Zayed, Roua A. Al-Rijjal, Lamya Al-Ghofaili, Huda A. BinEssa, Rajeev Pant, Anwar Alrabiah, Thamer Al-Hussainan, Minjing Zou, Brian F. Meyer, Yufei Shi

Orphanet J Rare Dis. 2021; 16: 100. Published online 2021 Feb 25. doi: 10.1186/s13023-021-01738-z

PMCID:: PMC7905910

Abstract Article PDF–1.6M

Select item 730723719.

Identification of Novel EXT Mutations in Patients with Hereditary Multiple Exostoses Using Whole‐Exome Sequencing

Chao Liang, Yong‐jie Wang, Yu‐xuan Wei, Yang Dong, Zhi‐chang Zhang

Orthop Surg. 2020 Jun; 12(3): 990–996. Published online 2020 Apr 15. doi: 10.1111/os.12660

PMCID:: PMC7307237

Abstract Article PDF–1.1M

Select item 720679320.

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling

Jin Huk Choi, Xue Zhong, William McAlpine, Tzu-Chieh Liao, Duanwu Zhang, Beibei Fang, Jamie Russell, Sara Ludwig, Evan Nair-Gill, Zhao Zhang, Kuan-wen Wang, Takuma Misawa, Xiaoming Zhan, Mihwa Choi, Tao Wang, Xiaohong Li, Miao Tang, Qihua Sun, Liyang Yu, Anne R. Murray, Eva Marie Y. Moresco, Bruce Beutler

Science. Author manuscript; available in PMC 2020 May 8.

Published in final edited form as: Science. 2019 May 10; 364(6440): eaau0812. doi: 10.1126/science.aau0812

PMCID:: PMC7206793

Abstract Article PDF–2.2M

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