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Select item 111727981.

Increased Expression of Orexin-A in Patients Affected by Polycystic Kidney Disease

Ersilia Nigro, Daniela D’Arco, Fiorenzo Moscatelli, Antonio Pisani, Maria Amicone, Eleonora Riccio, Ivana Capuano, Francesca Argentino, Marcellino Monda, Giovanni Messina, Aurora Daniele, Rita Polito

Int J Mol Sci. 2024 Jun; 25(11): 6243. Published online 2024 Jun 5. doi: 10.3390/ijms25116243

PMCID:: PMC11172798

Abstract Article PDF–717K

Select item 110583332.

Orexin‐A mediates glioblastoma proliferation inhibition by increasing ferroptosis triggered by unstable iron pools and GPX4 depletion

Rengzheng Huan, Jiqin Zhang, Jianhe Yue, Sha Yang, Guoqiang Han, Yuan Cheng, Ying Tan

J Cell Mol Med. 2024 May; 28(9): e18318. Published online 2024 Apr 29. doi: 10.1111/jcmm.18318

PMCID:: PMC11058333

Abstract Article PDF–51M

Select item 108526563.

Reduced Orexin-A Levels in Frontotemporal Dementia: Possible Association With Sleep Disturbance

Arzu Çoban, Başar Bilgiç, Ebba Lohmann, Cem İsmail Küçükali, Gülçin Benbir, Derya Karadeniz, Hasmet A. Hanagasi, Erdem Tüzün, Hakan Gürvit

Am J Alzheimers Dis Other Demen. 2013 Sep; 28(6): 606–611. Published online 2013 Jun 27. doi: 10.1177/1533317513494453

PMCID:: PMC10852656

Abstract Article PDF–159K

Select item 104549544.

Interaction of Orexin and Bone Morphogenetic Proteins in Steroidogenesis by Human Adrenocortical Cells

Yoshiaki Soejima, Nahoko Iwata, Ran Nishioka, Mako Honda, Yasuhiro Nakano, Koichiro Yamamoto, Atsuhito Suyama, Fumio Otsuka

Int J Mol Sci. 2023 Aug; 24(16): 12559. Published online 2023 Aug 8. doi: 10.3390/ijms241612559

PMCID:: PMC10454954

Abstract Article PDF–1018K

Select item 101220565.

Orexin induces the production of an endocannabinoid-derived lysophosphatidic acid eliciting hypothalamic synaptic loss in obesity

Alba Clara Fernández-Rilo, Nicola Forte, Letizia Palomba, Lea Tunisi, Fabiana Piscitelli, Roberta Imperatore, Alfonso Di Costanzo, Vincenzo Di Marzo, Luigia Cristino

Mol Metab. 2023 Jun; 72: 101713. Published online 2023 Mar 26. doi: 10.1016/j.molmet.2023.101713

PMCID:: PMC10122056

Abstract Article PDF–4.1M

Select item 101115446.

Attenuation of Hypocretin/Orexin Signaling Is Associated With Increased Mortality After Myocardial Infarction

Peter Wohlfahrt, Dominik Jenča, Vojtěch Melenovský, Petr Jarolím, Dana Dlouhá, Marek Šramko, Martin Kotrč, Michael Želízko, Jolana Mrázková, Jan Piťha, Věra Adámková, Josef Kautzner

J Am Heart Assoc. 2023 Mar 21; 12(6): e028987. Published online 2023 Mar 9. doi: 10.1161/JAHA.122.028987

PMCID:: PMC10111544

Abstract Article PDF–1.3M

Select item 93879837.

Differences in orexin-A level in the functional brain network of HUD patients undergoing harm reduction therapy

Wan-Ru You, Liang-Chun Lin, Wei-Che Lin, Meng-Chang Tsai

Medicine (Baltimore) 2022 Aug 19; 101(33): e30093. Published online 2022 Aug 19. doi: 10.1097/MD.0000000000030093

PMCID:: PMC9387983

Abstract Article PDF–620K

Select item 85056148.

Sleep dysregulation in binge eating disorder and “food addiction”: the orexin (hypocretin) system as a potential neurobiological link

Jacqueline B. Mehr, Deborah Mitchison, Hannah E. Bowrey, Morgan H. James

Neuropsychopharmacology. 2021 Nov; 46(12): 2051–2061. Published online 2021 Jun 18. doi: 10.1038/s41386-021-01052-z

PMCID:: PMC8505614

Abstract Article PDF–844K

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 809560910.

Hypocretin and Melanin‐Concentrating Hormone in Patients with Huntington Disease

Ahmad Aziz, Rolf Fronczek, Marion Maat‐Schieman, Unga Unmehopa, Freek Roelandse, Sebastiaan Overeem, Sjoerd Van Duinen, Gert‐Jan Lammers, Dick Swaab, Raymund Roos

Brain Pathol. 2008 Oct; 18(4): 474–483. Published online 2008 May 22. doi: 10.1111/j.1750-3639.2008.00135.x

PMCID:: PMC8095609

Abstract Article PDF–366K

Select item 726338011.

Circulating orexin changes during withdrawal are associated with nicotine craving and risk for smoking relapse

Mustafa al’Absi, Andrine Lemieux, James S. Hodges, Sharon Allen

Addict Biol. Author manuscript; available in PMC 2020 Jun 1.

Published in final edited form as: Addict Biol. 2019 Jul; 24(4): 743–753. Published online 2018 Aug 16. doi: 10.1111/adb.12643

PMCID:: PMC7263380

Abstract Article PDF–303K

Select item 669708112.

Higher Plasma Orexin A Levels in Children with Prader–Willi Syndrome Compared with Healthy Unrelated Sibling Controls

Ann M. Manzardo, Lisa Johnson, Jennifer L. Miller, Daniel J. Driscoll, Merlin G. Butler

Am J Med Genet A. Author manuscript; available in PMC 2019 Aug 15.

Published in final edited form as: Am J Med Genet A. 2016 Sep; 170(9): 2328–2333. doi: 10.1002/ajmg.a.37777

PMCID:: PMC6697081

Abstract Article PDF–162K

Select item 653652113.

Reduced Plasma Orexin-A Concentrations are Associated with Cognitive Deficits in Anorexia Nervosa

Trevor Steward, Gemma Mestre-Bach, Roser Granero, Isabel Sánchez, Nadine Riesco, Cristina Vintró-Alcaraz, Sarah Sauchelli, Susana Jiménez-Murcia, Zaida Agüera, Jose C. Fernández-García, Lourdes Garrido-Sánchez, Francisco J. Tinahones, Felipe F. Casanueva, Rosa M. Baños, Cristina Botella, Ana B. Crujeiras, Rafael de la Torre, Jose M. Fernández-Real, Gema Frühbeck, Francisco J. Ortega, Amaia Rodríguez, José M. Menchón, Fernando Fernández-Aranda

Sci Rep. 2019; 9: 7910. Published online 2019 May 27. doi: 10.1038/s41598-019-44450-6

PMCID:: PMC6536521

Abstract Article PDF–1.3M

Select item 618010614.

Knockdown of hypocretin attenuates extended access of cocaine self-administration in rats

Brooke E. Schmeichel, Alessandra Matzeu, Pascale Koebel, Leandro F. Vendruscolo, Harpreet Sidhu, Roxana Shahryari, Brigitte L. Kieffer, George F. Koob, Rémi Martin-Fardon, Candice Contet

Neuropsychopharmacology. 2018 Nov; 43(12): 2373–2382. Published online 2018 Apr 6. doi: 10.1038/s41386-018-0054-4

PMCID:: PMC6180106

Abstract Article PDF–1.2M

Select item 580658015.

Temporal Changes in the Cerebrospinal Fluid Level of Hypocretin-1 and Histamine in Narcolepsy

Régis Lopez, Lucie Barateau, Elisa Evangelista, Sofiene Chenini, Philippe Robert, Isabelle Jaussent, Yves Dauvilliers

Sleep. 2017 Jan 1; 40(1): zsw010. Published online 2017 Feb 9. doi: 10.1093/sleep/zsw010

PMCID:: PMC5806580

Abstract Article PDF–192K

Select item 563831516.

The relationship between orexin levels and blood pressure changes in patients with narcolepsy

Mariusz Sieminski, Kamil Chwojnicki, Tomi Sarkanen, Markku Partinen

PLoS One. 2017; 12(10): e0185975. Published online 2017 Oct 12. doi: 10.1371/journal.pone.0185975

PMCID:: PMC5638315

Abstract Article PDF–1.0M

Select item 558850717.

Association between Single Nucleotide Polymorphisms in Gamma-Aminobutyric Acid B Receptor, Insulin Receptor Substrate-1, and Hypocretin Neuropeptide Precursor Genes and Susceptibility to Obstructive Sleep Apnea Hypopnea Syndrome in a Chinese Han Population

Zhijun Li, Tingyu Tang, Jianzong Du, Wenjuan Wu, Xiaoxi Zhou, Guangyue Qin

Med Princ Pract. 2016 Nov; 25(6): 517–524. Published online 2016 Aug 10. doi: 10.1159/000448997

PMCID:: PMC5588507

Abstract Article PDF–182K

Select item 555729218.

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions

Kyuho Han, Edwin E. Jeng, Gaelen T. Hess, David W. Morgens, Amy Li, Michael C. Bassik

Nat Biotechnol. Author manuscript; available in PMC 2017 Sep 20.

Published in final edited form as: Nat Biotechnol. 2017 May; 35(5): 463–474. Published online 2017 Mar 20. doi: 10.1038/nbt.3834

PMCID:: PMC5557292

Abstract Article PDF–3.4M

Select item 486321419.

Orexin-A is Associated with Increases in Cerebrospinal Fluid Phosphorylated-Tau in Cognitively Normal Elderly Subjects

Ricardo S. Osorio, Emma L. Ducca, Margaret E. Wohlleber, Emily B. Tanzi, Tyler Gumb, Akosua Twumasi, Samuel Tweardy, Clifton Lewis, Esther Fischer, Viachaslau Koushyk, Maria Cuartero-Toledo, Mohammed O. Sheikh, Elizabeth Pirraglia, Henrik Zetterberg, Kaj Blennow, Shou-En Lu, Lisa Mosconi, Lidia Glodzik, Sonja Schuetz, Andrew W. Varga, Indu Ayappa, David M. Rapoport, Mony J. de Leon

Sleep. 2016 Jun 1; 39(6): 1253–1260. Published online 2016 Jun 1. doi: 10.5665/sleep.5846

PMCID:: PMC4863214

Abstract Article PDF–665K

Select item 483530220.

Hypocretin-1 Levels Associate with Fragmented Sleep in Patients with Narcolepsy Type 1

Anniina Alakuijala, Tomi Sarkanen, Markku Partinen

Sleep. 2016 May 1; 39(5): 1047–1050. Published online 2016 May 1. doi: 10.5665/sleep.5750

PMCID:: PMC4835302

Abstract Article PDF–250K

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