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Select item 112310141.

FERMT1 suppression induces anti-tumor effects and reduces stemness in glioma cancer cells

Zhigang Pan, Chuhan Ke, Hanlin Zheng, Xiumei Guo, Wen Gao, Xinyue Huang, Chunhui Chen, Yu Xiong, Shuni Zheng, Feng Zheng, Weipeng Hu

J Cancer Res Clin Oncol. 2024; 150(7): 338. Published online 2024 Jul 8. doi: 10.1007/s00432-024-05859-3

PMCID:: PMC11231014

Abstract Article PDF–9.5M

Select item 107827362.

FERMT1 promotes cell migration and invasion in non-small cell lung cancer via regulating PKP3-mediated activation of p38 MAPK signaling

Bao Liu, Yan Feng, Naiying Xie, Yang Yang, Dameng Yang

BMC Cancer. 2024; 24: 58. Published online 2024 Jan 10. doi: 10.1186/s12885-023-11812-3

PMCID:: PMC10782736

Abstract Article PDF–6.2M

Select item 100485343.

FERMT1 Is a Prognostic Marker Involved in Immune Infiltration of Pancreatic Adenocarcinoma Correlating with m⁶A Modification and Necroptosis

Qian Wu, Jin Li, Pei Wang, Qihang Peng, Zhongcui Kang, Yiting Deng, Jiayi Li, Dehong Yan, Feng Ge, Ying Chen

Genes (Basel) 2023 Mar; 14(3): 734. Published online 2023 Mar 16. doi: 10.3390/genes14030734

PMCID:: PMC10048534

Abstract Article PDF–14M

Select item 94339384.

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB

Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan

EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698

PMCID:: PMC9433938

Abstract Article PDF–9.3M

Select item 92792855.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 90290186.

Kindlin‐1 modulates the EGFR pathway and predicts sensitivity to EGFR inhibitors across cancer types

Paula Azorin, Florian Bonin, Zakia Tariq, Ambre Petitalot, Florence Coussy, Elisabetta Marangoni, Veronique Becette, Yves Denoux, Anne Vincent‐Salomon, Christophe Le Tourneau, Linda Larbi Cherif, Jerzy Klijanienko, Maud Kamal, Ivan Bièche, Rosette Lidereau, Keltouma Driouch

Clin Transl Med. 2022 Apr; 12(4): e813. Published online 2022 Apr 22. doi: 10.1002/ctm2.813

PMCID:: PMC9029018

Article PDF–3.7M

Select item 86098487.

FERMT1 knockdown inhibits oral squamous cell carcinoma cell epithelial-mesenchymal transition by inactivating the PI3K/AKT signaling pathway

Xiao Wang, Qianqian Chen

BMC Oral Health. 2021; 21: 598. Published online 2021 Nov 23. doi: 10.1186/s12903-021-01955-9

PMCID:: PMC8609848

Abstract Article PDF–1.6M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81498219.

Molecular motion and tridimensional nanoscale localization of kindlin control integrin activation in focal adhesions

Thomas Orré, Adrien Joly, Zeynep Karatas, Birgit Kastberger, Clément Cabriel, Ralph T. Böttcher, Sandrine Lévêque-Fort, Jean-Baptiste Sibarita, Reinhard Fässler, Bernhard Wehrle-Haller, Olivier Rossier, Grégory Giannone

Nat Commun. 2021; 12: 3104. Published online 2021 May 25. doi: 10.1038/s41467-021-23372-w

PMCID:: PMC8149821

Abstract Article PDF–6.9M

Select item 751553010.

FERMT1 promotes gastric cancer progression by activating the NF-κB pathway and predicts poor prognosis

Hua Fan, Shengjun Zhang, Yu Zhang, Wu liang, Bo Cao

Cancer Biol Ther. 2020; 21(9): 815–825. Published online 2020 Jul 29. doi: 10.1080/15384047.2020.1792218

PMCID:: PMC7515530

Abstract Article PDF–17M

Select item 711512811.

Targeting RICTOR sensitizes SMAD4-negative colon cancer to irinotecan

Chen Khuan Wong, Arthur William Lambert, Sait Ozturk, Panagiotis Papageorgis, Delia Lopez, Ning Shen, Zaina Sen, Hamid Mostafavi Abdolmaleky, Balázs Győrffy, Hui Feng, Sam Thiagalingam

Mol Cancer Res. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Mol Cancer Res. 2020 Mar; 18(3): 414–423. Published online 2020 Jan 13. doi: 10.1158/1541-7786.MCR-19-0525

PMCID:: PMC7115128

Abstract Article PDF–1.6M

Select item 638658812.

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2

Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari

Mol Cell. Author manuscript; available in PMC 2020 Feb 21.

Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001

PMCID:: PMC6386588

Abstract Article PDF–1.7M

Select item 634558413.

Kindlin-1 Regulates Epidermal Growth Factor Receptor Signaling

Magdalene Michael, Rumena Begum, Grace K. Chan, Austin J. Whitewood, Daniel R. Matthews, Benjamin T. Goult, John A. McGrath, Maddy Parsons

J Invest Dermatol. 2019 Feb; 139(2): 369–379. doi: 10.1016/j.jid.2018.08.020

PMCID:: PMC6345584

Abstract Article

Select item 604009214.

Kindlin supports platelet integrin αIIbβ3 activation by interacting with paxillin

Juan Gao, Ming Huang, Jingjing Lai, Kaijun Mao, Peisen Sun, Zhongyuan Cao, Youpei Hu, Yingying Zhang, Marie L. Schulte, Chaozhi Jin, Jian Wang, Gilbert C. White, Zhen Xu, Yan-Qing Ma

J Cell Sci. 2017 Nov 1; 130(21): 3764–3775. Published online 2017 Nov 1. doi: 10.1242/jcs.205641

PMCID:: PMC6040092

Abstract Article

Select item 589141715.

Proteomic profiling of VCP substrates links VCP to K6‐linked ubiquitylation and c‐Myc function

Jan B Heidelberger, Andrea Voigt, Marina E Borisova, Giuseppe Petrosino, Stefanie Ruf, Sebastian A Wagner, Petra Beli

EMBO Rep. 2018 Apr; 19(4): e44754. Published online 2018 Feb 21. doi: 10.15252/embr.201744754

PMCID:: PMC5891417

Abstract Article PDF–1.0M

Select item 586483216.

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations

Xiaonan Liu, Kari Salokas, Fitsum Tamene, Yaming Jiu, Rigbe G. Weldatsadik, Tiina Öhman, Markku Varjosalo

Nat Commun. 2018; 9: 1188. Published online 2018 Mar 22. doi: 10.1038/s41467-018-03523-2

PMCID:: PMC5864832

Abstract Article PDF–4.5M

Select item 575653917.

Kindlin-1 Regulates Keratinocyte Electrotaxis

Gaofeng Zhang, Yu Gu, Rumena Begum, Hongduo Chen, Xinghua Gao, John A. McGrath, Maddy Parsons, Bing Song

J Invest Dermatol. 2016 Nov; 136(11): 2229–2239. doi: 10.1016/j.jid.2016.05.129

PMCID:: PMC5756539

Abstract Article

Select item 553161118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 536043719.

Kindlin-1 contributes to EGF-induced re-epithelialization in skin wound healing

Congcong Shen, Linlin Sun, Ningwen Zhu, Fazhi Qi

Int J Mol Med. 2017 Apr; 39(4): 949–959. Published online 2017 Mar 7. doi: 10.3892/ijmm.2017.2911

PMCID:: PMC5360437

Abstract Article PDF–1.9M

Select item 534280920.

Focal adhesion molecule Kindlin-1 mediates activation of TGF-β signaling by interacting with TGF-βRI, SARA and Smad3 in colorectal cancer cells

Jinfeng Kong, Juan Du, Yunling Wang, Mingzi Yang, Jianchao Gao, Xiaofan Wei, Weigang Fang, Jun Zhan, Hongquan Zhang

Oncotarget. 2016 Nov 15; 7(46): 76224–76237. Published online 2016 Oct 20. doi: 10.18632/oncotarget.12779

PMCID:: PMC5342809

Abstract Article PDF–8.4M

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