PMC Links for GEO Profiles (Select 77992658) - PMC

Select item 86297851.

Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter

Dolores Piniella, Elena Martínez-Blanco, David Bartolomé-Martín, Ana B. Sanz-Martos, Francisco Zafra

Cell Mol Life Sci. 2021 Dec; 78(23): 7733–7756. Published online 2021 Oct 28. doi: 10.1007/s00018-021-03998-1

PMCID:: PMC8629785

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79490373.

The allosteric inhibition of glycine transporter 2 by bioactive lipid analgesics is controlled by penetration into a deep lipid cavity

Katie A. Wilson, Shannon N. Mostyn, Zachary J. Frangos, Susan Shimmon, Tristan Rawling, Robert J. Vandenberg, Megan L. O’Mara

J Biol Chem. 2021 Jan-Jun; 296: 100282. Published online 2021 Jan 12. doi: 10.1016/j.jbc.2021.100282

PMCID:: PMC7949037

Abstract Article PDF–2.9M

Select item 72066144.

Photoswitchable ORG25543 Congener Enables Optical Control of Glycine Transporter 2

Shannon N. Mostyn, Subhodeep Sarker, Parthasarathy Muthuraman, Arun Raja, Susan Shimmon, Tristan Rawling, Christopher L. Cioffi, Robert J. Vandenberg

ACS Chem Neurosci. 2020 May 6; 11(9): 1250–1258. Published online 2020 Mar 19. doi: 10.1021/acschemneuro.9b00655

PMCID:: PMC7206614

Abstract Article PDF–2.2M

Select item 55316115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 43036676.

Molecular Basis of the Dominant Negative Effect of a Glycine Transporter 2 Mutation Associated with Hyperekplexia

Esther Arribas-González, Jaime de Juan-Sanz, Carmen Aragón, Beatriz López-Corcuera

J Biol Chem. 2015 Jan 23; 290(4): 2150–2165. Published online 2014 Dec 5. doi: 10.1074/jbc.M114.587055

PMCID:: PMC4303667

Abstract Article PDF–3.3M

Select item 39496537.

Reversible inhibition of the glycine transporter GlyT2 circumvents acute toxicity while preserving efficacy in the treatment of pain

A Mingorance-Le Meur, P Ghisdal, B Mullier, P De Ron, P Downey, C Van Der Perren, V Declercq, S Cornelis, M Famelart, J Van Asperen, E Jnoff, J P Courade

Br J Pharmacol. 2013 Nov; 170(5): 1053–1063. Published online 2013 Oct 15. doi: 10.1111/bph.12343

PMCID:: PMC3949653

Abstract Article PDF–940K

Select item 35901328.

Constitutive Endocytosis and Turnover of the Neuronal Glycine Transporter GlyT2 Is Dependent on Ubiquitination of a C-Terminal Lysine Cluster

Jaime de Juan-Sanz, Enrique Núñez, Beatriz López-Corcuera, Carmen Aragón

PLoS One. 2013; 8(3): e58863. Published online 2013 Mar 6. doi: 10.1371/journal.pone.0058863

PMCID:: PMC3590132

Abstract Article PDF–1.9M

Select item 35225879.

Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population

Anthony G. Comuzzie, Shelley A. Cole, Sandra L. Laston, V. Saroja Voruganti, Karin Haack, Richard A. Gibbs, Nancy F. Butte

PLoS One. 2012; 7(12): e51954. Published online 2012 Dec 14. doi: 10.1371/journal.pone.0051954

PMCID:: PMC3522587

Abstract Article PDF–130K

Select item 343655510.

Mutations in the GlyT2 Gene (SLC6A5) Are a Second Major Cause of Startle Disease

Eloisa Carta, Seo-Kyung Chung, Victoria M. James, Angela Robinson, Jennifer L. Gill, Nathalie Remy, Jean-François Vanbellinghen, Cheney J. G. Drew, Sophie Cagdas, Duncan Cameron, Frances M. Cowan, Mireria Del Toro, Gail E. Graham, Adnan Y. Manzur, Amira Masri, Serge Rivera, Emmanuel Scalais, Rita Shiang, Kate Sinclair, Catriona A. Stuart, Marina A. J. Tijssen, Grahame Wise, Sameer M. Zuberi, Kirsten Harvey, Brian R. Pearce, Maya Topf, Rhys H. Thomas, Stéphane Supplisson, Mark I. Rees, Robert J. Harvey

J Biol Chem. 2012 Aug 17; 287(34): 28975–28985. Published online 2012 Jun 14. doi: 10.1074/jbc.M112.372094

PMCID:: PMC3436555

Abstract Article PDF–3.3M

Select item 343653711.

A Novel Dominant Hyperekplexia Mutation Y705C Alters Trafficking and Biochemical Properties of the Presynaptic Glycine Transporter GlyT2

Cecilio Giménez, Gonzalo Pérez-Siles, Jaime Martínez-Villarreal, Esther Arribas-González, Esperanza Jiménez, Enrique Núñez, Jaime de Juan-Sanz, Enrique Fernández-Sánchez, Noemí García-Tardón, Ignacio Ibáñez, Valeria Romanelli, Julián Nevado, Victoria M. James, Maya Topf, Seo-Kyung Chung, Rhys H. Thomas, Lourdes R. Desviat, Carmen Aragón, Francisco Zafra, Mark I. Rees, Pablo Lapunzina, Robert J. Harvey, Beatriz López-Corcuera

J Biol Chem. 2012 Aug 17; 287(34): 28986–29002. Published online 2012 Jun 29. doi: 10.1074/jbc.M111.319244

PMCID:: PMC3436537

Abstract Article PDF–3.4M

Select item 320441112.

Mutations in the human GlyT2 gene define a presynaptic component of human startle disease

Mark I. Rees, Kirsten Harvey, Brian R. Pearce, Seo-Kyung Chung, Ian C. Duguid, Philip Thomas, Sarah Beatty, Gail E. Graham, Linlea Armstrong, Rita Shiang, Kim J. Abbott, Sameer M. Zuberi, John B.P. Stephenson, Michael J. Owen, Marina A.J. Tijssen, Arn M.J.M. van den Maagdenberg, Trevor G. Smart, Stéphane Supplisson, Robert J. Harvey

Nat Genet. Author manuscript; available in PMC 2011 Oct 31.

Published in final edited form as: Nat Genet. 2006 Jul; 38(7): 801–806. Published online 2006 Jun 4. doi: 10.1038/ng1814

PMCID:: PMC3204411

Abstract Article PDF–1.7M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 294744114.

Glycinergic Pacemaker Neurons in PreBötzinger Complex of Neonatal Mouse

Consuelo Morgado-Valle, Serapio M. Baca, Jack L. Feldman

J Neurosci. 2010 Mar 10; 30(10): 3634–3639. doi: 10.1523/JNEUROSCI.3040-09.2010

PMCID:: PMC2947441

Abstract Article PDF–737K

Select item 249160715.

Association study of polymorphisms in the neutral amino acid transporter genes SLC1A4, SLC1A5 and the glycine transporter genes SLC6A5, SLC6A9 with schizophrenia

Xiangdong Deng, Noriaki Sagata, Naoko Takeuchi, Masami Tanaka, Hideaki Ninomiya, Nakao Iwata, Norio Ozaki, Hiroki Shibata, Yasuyuki Fukumaki

BMC Psychiatry. 2008; 8: 58. Published online 2008 Jul 18. doi: 10.1186/1471-244X-8-58

PMCID:: PMC2491607

Abstract Article PDF–388K

Select item 118208916.

The Novel Gene Encoding a Putative Transmembrane Protein Is Mutated in Gnathodiaphyseal Dysplasia (GDD)

Satoshi Tsutsumi, Nobuyuki Kamata, Tamara J. Vokes, Yutaka Maruoka, Koichi Nakakuki, Shoji Enomoto, Ken Omura, Teruo Amagasa, Masaru Nagayama, Fumiko Saito-Ohara, Johji Inazawa, Maki Moritani, Takashi Yamaoka, Hiroshi Inoue, Mitsuo Itakura

Am J Hum Genet. 2004 Jun; 74(6): 1255–1261. Published online 2004 Apr 29. doi: 10.1086/421527

PMCID:: PMC1182089

Abstract Article PDF–955K

Select item 52892817.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

Select item 13924118.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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