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Items: 1 to 20 of 60

1.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
2.
Combination of FOXD1 and Plk2: A novel biomarker for predicting unfavourable prognosis of colorectal cancer
Yaping Zong, Yiming Miao, Wenchang Li, Minhua Zheng, Zhuoqing Xu, Han Gao, Wenqing Feng, Zifeng Xu, Jingkun Zhao, Lifei Shen, Aiguo Lu
J Cell Mol Med. 2022 Jun; 26(12): 3471–3482. Published online 2022 May 17. doi: 10.1111/jcmm.17361
PMCID:
PMC9189346
AbstractArticlePDF–15M
3.
Polo-like kinases as potential targets and PLK2 as a novel biomarker for the prognosis of human glioblastoma
Yiming Ding, Hanjie Liu, Chuanbao Zhang, Zhaoshi Bao, Shuqing Yu
Aging (Albany NY) 2022 Mar 15; 14(5): 2320–2334. Published online 2022 Mar 7. doi: 10.18632/aging.203940
PMCID:
PMC8954957
AbstractArticlePDF–3.7M
4.
Circular RNA 0102049 suppresses the progression of osteosarcoma through modulating miR-520g-3p/PLK2 axis
Xianliao Zhang, Zhengbo Hu, Wenhu Li, Zhongxun Liu, Jie Li, Zhaozhen Wang, Vidmi Taolam Martin, Bing Yan, Bo Yu
Bioengineered. 2021; 12(1): 2022–2032. Published online 2021 Jun 1. doi: 10.1080/21655979.2021.1923259
PMCID:
PMC8806202
AbstractArticlePDF–2.6M
5.
Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation
Stephan R. Künzel, Maximilian Hoffmann, Silvio Weber, Karolina Künzel, Susanne Kämmerer, Mario Günscht, Erik Klapproth, Johanna S.E. Rausch, Mirna S. Sadek, Tomasz Kolanowski, Stefanie Meyer-Roxlau, Christopher Piorkowski, Sems M. Tugtekin, Stefan Rose-John, Xiaoke Yin, Manuel Mayr, Jan Dominik Kuhlmann, Pauline Wimberger, Konrad Grützmann, Natalie Herzog, Jan-Heiner Küpper, Molly O’Reilly, S. Nashitha Kabir, Laura C. Sommerfeld, Kaomei Guan, Ben Wielockx, Larissa Fabritz, Stanley Nattel, Ursula Ravens, Dobromir Dobrev, Michael Wagner, Ali El-Armouche
Circ Res. 2021 Oct 1; 129(8): 804–820. Published online 2021 Aug 26. doi: 10.1161/CIRCRESAHA.121.319425
PMCID:
PMC8487716
AbstractArticlePDF–11M
6.
Identification and assessment of PLK1/2/3/4 in lung adenocarcinoma and lung squamous cell carcinoma: Evidence from methylation profile
Sisi Deng, Xiaoli Lu, Zhi Zhang, Rui Meng, Mi Li, Shilin Xia
J Cell Mol Med. 2021 Jul; 25(14): 6652–6663. Published online 2021 Jun 2. doi: 10.1111/jcmm.16668
PMCID:
PMC8278123
AbstractArticlePDF–2.2M
7.
miR-101-3p Contributes to α-Synuclein Aggregation in Neural Cells through the miR-101-3p/SKP1/PLK2 Pathway
Min Zhang, Wei Liu, Qingan Zhang, Hongfeng Hu
J Healthc Eng. 2021; 2021: 6147434. Published online 2021 Jun 12. doi: 10.1155/2021/6147434
PMCID:
PMC8216813
AbstractArticlePDF–2.1M
8.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
9.
Genetic Deletion of Polo-Like Kinase 2 Induces a Pro-Fibrotic Pulmonary Phenotype
Theresa A. Kant, Manja Newe, Luise Winter, Maximilian Hoffmann, Susanne Kämmerer, Erik Klapproth, Karolina Künzel, Mark P. Kühnel, Lavinia Neubert, Ali El-Armouche, Stephan R. Künzel
Cells. 2021 Mar; 10(3): 617. Published online 2021 Mar 11. doi: 10.3390/cells10030617
PMCID:
PMC8001503
AbstractArticlePDF–3.3M
10.
Phosphorylation of Synaptic GTPase-activating Protein (synGAP) by Polo-Like Kinase (Plk2) alters the Ratio of Its GAP Activity toward HRas, Rap1 and Rap2 GTPases
Ward G. Walkup, 4th, Michael J. Sweredoski, Robert L. Graham, Sonja Hess, Mary B. Kennedy
Biochem Biophys Res Commun. Author manuscript; available in PMC 2021 Feb 19.
Published in final edited form as: Biochem Biophys Res Commun. 2018 Sep 10; 503(3): 1599–1604. Published online 2018 Jul 24. doi: 10.1016/j.bbrc.2018.07.087
PMCID:
PMC7894274
AbstractArticlePDF–1016K
11.
Structural analysis of the polo-box domain of human Polo-like kinase 2
Ju Hee Kim, Bonsu Ku, Kyung S. Lee, Seung Jun Kim
Proteins. Author manuscript; available in PMC 2020 Dec 7.
Published in final edited form as: Proteins. 2015 Jul; 83(7): 1201–1208. Published online 2015 Apr 28. doi: 10.1002/prot.24804
PMCID:
PMC7720676
AbstractArticlePDF–1.5M
12.
Loss of PLK2 induces acquired resistance to temozolomide in GBM via activation of notch signaling
Wahafu Alafate, Dongze Xu, Wei Wu, Jianyang Xiang, Xudong Ma, Wanfu Xie, Xiaobin Bai, Maode Wang, Jia Wang
J Exp Clin Cancer Res. 2020; 39: 239. Published online 2020 Nov 11. doi: 10.1186/s13046-020-01750-4
PMCID:
PMC7657349
AbstractArticlePDF–4.3M
13.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
14.
Insulin Resistance Promotes Parkinson’s Disease through Aberrant Expression of α-Synuclein, Mitochondrial Dysfunction, and Deregulation of the Polo-Like Kinase 2 Signaling
Chien-Tai Hong, Kai-Yun Chen, Weu Wang, Jing-Yuan Chiu, Dean Wu, Tsu-Yi Chao, Chaur-Jong Hu, Kai-Yin David Chau, Oluwaseun Adebayo Bamodu
Cells. 2020 Mar; 9(3): 740. Published online 2020 Mar 17. doi: 10.3390/cells9030740
PMCID:
PMC7140619
AbstractArticlePDF–2.0M
15.
Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication
Hongbo Ling, Lirong Peng, Jianbo Wang, Raneen Rahhal, Edward Seto
Cell Rep. Author manuscript; available in PMC 2019 Oct 25.
Published in final edited form as: Cell Rep. 2018 Dec 4; 25(10): 2851–2865.e3. doi: 10.1016/j.celrep.2018.11.025
PMCID:
PMC6814291
AbstractArticlePDF–3.1M
16.
Plk2 Loss Commonly Occurs in Colorectal Carcinomas but not Adenomas: Relationship to mTOR Signaling
Elizabeth M. Matthew, Zhaohai Yang, Suraj Peri, Mark Andrake, Roland Dunbrack, Eric Ross, Wafik S. El-Deiry
Neoplasia. 2018 Mar; 20(3): 244–255. Published online 2018 Feb 12. doi: 10.1016/j.neo.2018.01.004
PMCID:
PMC5849802
AbstractArticlePDF–4.0M
17.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M
18.
The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery
Ramesh Kumar, Román González-Prieto, Zhenyu Xiao, Matty Verlaan-de Vries, Alfred C. O. Vertegaal
Nat Commun. 2017; 8: 1809. Published online 2017 Nov 27. doi: 10.1038/s41467-017-01900-x
PMCID:
PMC5703878
AbstractArticlePDF–3.7M
19.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
20.
Dissecting the Molecular Pathway Involved in PLK2 Kinase-mediated α-Synuclein-selective Autophagic Degradation
Manel Dahmene, Morgan Bérard, Abid Oueslati
J Biol Chem. 2017 Mar 3; 292(9): 3919–3928. Published online 2017 Jan 30. doi: 10.1074/jbc.M116.759373
PMCID:
PMC5339772
AbstractArticlePDF–1.3M

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