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Select item 105527441.

Long non-coding RNA NMRAL2P promotes glycolysis and reduces ROS in head and neck tumors by interacting with the ENO1 protein and promoting GPX2 transcription

Qian Nie, Huan Cao, JianWang Yang, Tao Liu, BaoShan Wang

PeerJ. 2023; 11: e16140. Published online 2023 Oct 2. doi: 10.7717/peerj.16140

PMCID:: PMC10552744

Abstract Article PDF–11M

Select item 105189772.

ACVRL1 drives resistance to multitarget tyrosine kinase inhibitors in colorectal cancer by promoting USP15-mediated GPX2 stabilization

Xiaolin Lu, Ruiqi Liu, Yuanyu Liao, Luying Cui, Haoxiu Sun, Dongzhi Zhang, Bojun Wang, Lin Fang, Xin Guan, Yuanfei Yao, Chao Liu, Yanqiao Zhang

BMC Med. 2023; 21: 366. Published online 2023 Sep 25. doi: 10.1186/s12916-023-03066-4

PMCID:: PMC10518977

Abstract Article PDF–18M

Select item 102566123.

Glutathione peroxidase 2 knockdown suppresses gastric cancer progression and metastasis via regulation of kynurenine metabolism

Handong Xu, Can Hu, Yi Wang, Yunfu Shi, Li Yuan, Jingli Xu, Yanqiang Zhang, Jiahui Chen, Qin Wei, Jiangjiang Qin, Zhiyuan Xu, Xiangdong Cheng

Oncogene. 2023; 42(24): 1994–2006. Published online 2023 May 3. doi: 10.1038/s41388-023-02708-4

PMCID:: PMC10256612

Abstract Article PDF–8.0M

Select item 98273804.

Side-by-side comparison of recombinant human glutathione peroxidases identifies overlapping substrate specificities for soluble hydroperoxides

Maria Schwarz, Alina Löser, Qing Cheng, Mareike Wichmann-Costaganna, Patrick Schädel, Oliver Werz, Elias SJ. Arnér, Anna P. Kipp

Redox Biol. 2023 Feb; 59: 102593. Published online 2023 Jan 2. doi: 10.1016/j.redox.2022.102593

PMCID:: PMC9827380

Abstract Article PDF–3.0M

Select item 95797495.

Glutathione peroxidase 2 overexpression promotes malignant progression and cisplatin resistance of KRAS-mutated lung cancer cells

Mei Wang, Xu Chen, Guang Fu, Mingjian Ge

Oncol Rep. 2022 Dec; 48(6): 207. Published online 2022 Oct 10. doi: 10.3892/or.2022.8422

Retraction in:: Oncol Rep. 2025 Jan; 53(1): 1.

PMCID:: PMC9579749

Abstract Article

Select item 88727796.

Redox signaling by glutathione peroxidase 2 links vascular modulation to metabolic plasticity of breast cancer

Zuen Ren, Huizhi Liang, Phillip M. Galbo, Jr, Malindrie Dharmaratne, Ameya S. Kulkarni, Atefeh Taherian Fard, Marie Louise Aoun, Nuria Martinez-Lopez, Kimita Suyama, Outhiriaradjou Benard, Wei Zheng, Yang Liu, Joseph Albanese, Deyou Zheng, Jessica C. Mar, Rajat Singh, Michael B. Prystowsky, Larry Norton, Rachel B. Hazan

Proc Natl Acad Sci U S A. 2022 Feb 22; 119(8): e2107266119. Published online 2022 Feb 22. doi: 10.1073/pnas.2107266119

PMCID:: PMC8872779

Abstract Article PDF–2.9M

Select item 80451167.

Reduced Expression Level of GPX2 in T1 Bladder Cancer and its Role in Early-phase Invasion of Bladder Cancer

AKINORI MINATO, HIROTSUGU NOGUCHI, REI OHNISHI, IKKO TOMISAKI, TOSHIYUKI NAKAYAMA, NAOHIRO FUJIMOTO

In Vivo. 2021 Mar-Apr; 35(2): 753–759. Published online 2021 Mar 3. doi: 10.21873/invivo.12316

PMCID:: PMC8045116

Abstract Article PDF–3.6M

Select item 70792208.

Elevated Glutathione Peroxidase 2 Expression Promotes Cisplatin Resistance in Lung Adenocarcinoma

He Du, Bi Chen, Nan-Lin Jiao, Yan-Hua Liu, San-Yuan Sun, You-Wei Zhang

Oxid Med Cell Longev. 2020; 2020: 7370157. Published online 2020 Mar 6. doi: 10.1155/2020/7370157

PMCID:: PMC7079220

Abstract Article PDF–2.0M

Select item 68833229.

Distinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-κB-driven inflammation through redox-active mechanisms

Solveigh C. Koeberle, André Gollowitzer, Jamila Laoukili, Onno Kranenburg, Oliver Werz, Andreas Koeberle, Anna P. Kipp

Redox Biol. 2020 Jan; 28: 101388. Published online 2019 Nov 16. doi: 10.1016/j.redox.2019.101388

PMCID:: PMC6883322

Abstract Article PDF–2.8M

Select item 493622910.

Clinicopathological and prognostic significance of GPX2 protein expression in esophageal squamous cell carcinoma

Zhijin Lei, Dongping Tian, Chong Zhang, Shukun Zhao, Min Su

BMC Cancer. 2016; 16: 410. Published online 2016 Jul 7. doi: 10.1186/s12885-016-2462-3

PMCID:: PMC4936229

Abstract Article PDF–2.4M

Select item 326170811.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67

Correction in:: Mol Syst Biol. 2017 Dec; 13(12): 965.

PMCID:: PMC3261708

Abstract Article PDF–2.0M

Select item 322018612.

Genetic Susceptibility to Distinct Bladder Cancer Subphenotypes

Lin T. Guey, Montserrat García-Closas, Cristiane Murta-Nascimento, Josep Lloreta, Laia Palencia, Manolis Kogevinas, Nathaniel Rothman, Gemma Vellalta, Malu Calle, Gaëlle Marenne, Adonina Tardón, Alfredo Carrato, Reina García-Closas, Consol Serra, Debra T Silverman, Stephen Chanock, Francisco X. Real, Núria Malats

Eur Urol. Author manuscript; available in PMC 2011 Nov 18.

Published in final edited form as: Eur Urol. 2010 Feb; 57(2): 283–292. Published online 2009 Aug 12. doi: 10.1016/j.eururo.2009.08.001

PMCID:: PMC3220186

Abstract Article PDF–595K

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 296777214.

Polymorphisms in DNA repair genes and risk of non-Hodgkin lymphoma in a pooled analysis of three studies

Min Shen, Idan Menashe, Sophia S. Wang, Yawei Zhang, Bruce Armstrong, Lindsay M. Morton, Qing Lan, Patricia Hartge, Mark P. Purdue, James R. Cerhan, Andrew Grulich, Wendy Cozen, Meredith Yeager, Theodore R. Holford, Claire M. Vajdic, Scott Davis, Brian Leaderer, Anne Kricker, Maryjean Schenk, Shelia H. Zahm, Nilanjan Chatterjee, Nathaniel Rothman, Stephen J. Chanock, Tongzhang Zheng

Br J Haematol. Author manuscript; available in PMC 2010 Nov 2.

Published in final edited form as: Br J Haematol. 2010 Nov; 151(3): 239–244. Published online 2010 Aug 31. doi: 10.1111/j.1365-2141.2010.08364.x

PMCID:: PMC2967772

Abstract Article PDF–142K

Select item 294516815.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

Select item 292822416.

Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity

HD Hosgood, III, L Zhang, M Shen, SI Berndt, R Vermeulen, G Li, S Yin, M Yeager, J Yuenger, N Rothman, S Chanock, M Smith, Q Lan

Occup Environ Med. Author manuscript; available in PMC 2010 Dec 1.

Published in final edited form as: Occup Environ Med. 2009 Dec; 66(12): 848–853. Published online 2009 Sep 22. doi: 10.1136/oem.2008.044024

PMCID:: PMC2928224

Abstract Article PDF–321K

Select item 289025117.

Common Genetic Variants in Candidate Genes and Risk of Familial Lymphoid Malignancies

Xueying (Sharon) Liang, Neil Caporaso, Mary Lou McMaster, David Ng, Ola Landgren, Meredith Yeager, Stephen Chanock, Lynn R. Goldin

Br J Haematol. Author manuscript; available in PMC 2010 Jun 23.

Published in final edited form as: Br J Haematol. 2009 Aug; 146(4): 418–423. Published online 2009 Jul 1. doi: 10.1111/j.1365-2141.2009.07790.x

PMCID:: PMC2890251

Abstract Article PDF–58K

Select item 283736718.

Glutathione Pathway Genetic Polymorphisms and Lung Cancer Survival After Platinum-Based Chemotherapy

Ann M. Moyer, Zhifu Sun, Anthony J. Batzler, Liang Li, Daniel J. Schaid, Ping Yang, Richard M. Weinshilboum

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2011 Mar 3.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 Mar; 19(3): 811–821. Published online 2010 Mar 3. doi: 10.1158/1055-9965.EPI-09-0871

PMCID:: PMC2837367

Abstract Article PDF–1.5M

Select item 278379919.

PTEN IDENTIFIED AS IMPORTANT RISK FACTOR OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

H Dean Hosgood, III, Idan Menashe, Xingzhou He, Stephen Chanock, Qing Lan

Respir Med. Author manuscript; available in PMC 2010 Dec 1.

Published in final edited form as: Respir Med. 2009 Dec; 103(12): 1866–1870. Published online 2009 Jul 21. doi: 10.1016/j.rmed.2009.06.016

PMCID:: PMC2783799

Abstract Article PDF–315K

Select item 277583220.

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani

Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014

PMCID:: PMC2775832

Abstract Article PDF–2.8M

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