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Select item 74834061.

HPP1 Ectodomain Shedding is Mediated by ADAM17 and is Necessary for Tumor Suppression in Colon Cancer

Abul Elahi, Abidemi Ajidahun, Leah Hendrick, Irina Getun, Leigh Ann Humphries, Jonathan Hernandez, David Shibata

J Surg Res. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: J Surg Res. 2020 Oct; 254: 183–190. Published online 2020 May 22. doi: 10.1016/j.jss.2020.04.010

PMCID:: PMC7483406

Abstract Article PDF–1.4M

Select item 71699832.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 70115733.

MiR-323-3p Targeting Transmembrane Protein with EGF-Like and 2 Follistatin Domain (TMEFF2) Inhibits Human Lung Cancer A549 Cell Apoptosis by Regulation of AKT and ERK Signaling Pathways

Ji-min Fan, Zheng-rong Zheng, Yi-Ming Zeng, Xiao-yang Chen

Med Sci Monit. 2020; 26: e919454-1–e919454-11. Published online 2020 Feb 3. doi: 10.12659/MSM.919454

PMCID:: PMC7011573

Abstract Article PDF–2.5M

Select item 65100564.

Expression of TMEFF2 in Human Pancreatic Cancer Tissue and the Effects of TMEFF2 Knockdown on Cell, Proliferation, and Apoptosis in Human Pancreatic Cell Lines

Kailiang Li, Wenjing Gu, Jie Xu, Aikun Wang, Hongchao Han

Med Sci Monit. 2019; 25: 3238–3246. Published online 2019 May 2. doi: 10.12659/MSM.913974

PMCID:: PMC6510056

Abstract Article PDF–2.0M

Select item 65033805.

A TMEFF2-regulated cell cycle derived gene signature is prognostic of recurrence risk in prostate cancer

Constantin Georgescu, Joshua M. Corbin, Sandra Thibivilliers, Zachary D. Webb, Yan D. Zhao, Jan Koster, Kar-Ming Fung, Adam S. Asch, Jonathan D. Wren, Maria J. Ruiz-Echevarría

BMC Cancer. 2019; 19: 423. Published online 2019 May 6. doi: 10.1186/s12885-019-5592-6

PMCID:: PMC6503380

Abstract Article PDF–1.6M

Select item 58368826.

TMEFF2 shedding is regulated by oxidative stress and mediated by ADAMs and transmembrane serine proteases implicated in prostate cancer

Katarzyna Gaweł‐Bęben, Nazim Ali, Vincent Ellis, Gloria Velasco, Zaruhi Poghosyan, Ann Ager, Vera Knäuper

Cell Biol Int. 2018 Mar; 42(3): 273–280. Published online 2017 Aug 21. doi: 10.1002/cbin.10832

PMCID:: PMC5836882

Abstract Article PDF–872K

Select item 55331017.

Tomoregulin (TMEFF2) Binds Alzheimer’s Disease Amyloid-β (Aβ) Oligomer and AβPP and Protects Neurons from Aβ-Induced Toxicity

Hyun-Seok Hong, Izumi Maezawa, Jitka Petrlova, Xiao-Yan Zhao, John C. Voss, Lee-Way Jin

J Alzheimers Dis. Author manuscript; available in PMC 2017 Jul 28.

Published in final edited form as: J Alzheimers Dis. 2015; 48(3): 731–743. doi: 10.3233/JAD-150318

PMCID:: PMC5533101

Abstract Article PDF–1.3M

Select item 54952258.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 53717309.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 483226310.

Four DNA methylation biomarkers in biliary brush samples accurately identify the presence of cholangiocarcinoma

Kim Andresen, Kirsten Muri Boberg, Hege Marie Vedeld, Hilde Honne, Peter Jebsen, Merete Hektoen, Christopher A. Wadsworth, Ole Petter Clausen, Knut E.A. Lundin, Vemund Paulsen, Aksel Foss, Øystein Mathisen, Lars Aabakken, Erik Schrumpf, Ragnhild A. Lothe, Guro E. Lind

Hepatology. 2015 May; 61(5): 1651–1659. Published online 2015 Feb 24. doi: 10.1002/hep.27707

PMCID:: PMC4832263

Abstract Article PDF–538K

Select item 429813011.

The Genetics of Hemoglobin A₂ Regulation in Sickle Cell Anemia

Paula J. Griffin, Paola Sebastiani, Heather Edward, Clinton T. Baldwin, Mark Gladwin, Victor Gordeuk, David H.K. Chui, Martin H. Steinberg

Am J Hematol. Author manuscript; available in PMC 2015 Nov 1.

Published in final edited form as: Am J Hematol. 2014 Nov; 89(11): 1019–1023. Published online 2014 Aug 4. doi: 10.1002/ajh.23811

PMCID:: PMC4298130

Abstract Article PDF–712K

Select item 412886212.

The interplay between histone deacetylases and c-Myc in the transcriptional suppression of HPP1 in colon cancer

Jian Wang, Abul Elahi, Abidemi Ajidahun, Whalen Clark, Jonathan Hernandez, Alex Achille, Ji-hui Hao, Edward Seto, David Shibata

Cancer Biol Ther. 2014 Sep 1; 15(9): 1198–1207. Published online 2014 Jun 11. doi: 10.4161/cbt.29500

PMCID:: PMC4128862

Abstract Article PDF–2.4M

Select item 406593613.

Detection of aberrant methylation in fecal DNA as a molecular screening tool for colorectal cancer and precancerous lesions

Zhao-Hui Huang, Li-Hua Li, Fan Yang, Jin-Fu Wang

World J Gastroenterol. 2007 Feb 14; 13(6): 950–954. Published online 2007 Feb 14. doi: 10.3748/wjg.v13.i6.950

PMCID:: PMC4065936

Abstract Article PDF–1.6M

Select item 402170814.

THE TMEFF2 TUMOR SUPPRESSOR MODULATES INTEGRIN EXPRESSION, RHOA ACTIVATION AND MIGRATION OF PROSTATE CANCER CELLS

Xiaofei Chen, Joshua M. Corbin, Greg J. Tipton, Li V. Yang, Adam S. Asch, Maria J. Ruiz-Echevarría

Biochim Biophys Acta. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Biochim Biophys Acta. 2014 Jun; 1843(6): 1216–1224. Published online 2014 Mar 13. doi: 10.1016/j.bbamcr.2014.03.005