PMC Links for GEO Profiles (Select 78989584) - PMC

Select item 91133231.

The hyper-expression of NLRP4 characterizes the occurrence of macrophage activation syndrome assessing STING pathway in adult-onset Still’s disease

Piero Ruscitti, Onorina Berardicurti, Ilenia Di Cola, Claudia Di Muzio, Elena Di Nino, Roberto Giacomelli, Paola Cipriani

Clin Exp Immunol. 2022 Apr; 208(1): 95–102. Published online 2022 Feb 2. doi: 10.1093/cei/uxac014

PMCID:: PMC9113323

Abstract Article PDF–1.4M

Select item 88987292.

NLRP4 negatively regulates type I interferon response and influences the outcome in anti‐programmed cell death protein (PD)‐1/PD‐ligand 1 therapy

Hui Wang, Liliang Xia, Cheng‐cheng Yao, Hui Dong, Yi Yang, Chong Li, Wen‐xiang Ji, Rui‐ming Sun, Huang‐qi Duan, Wenli Mengzhou, Wei‐min Xia, Shu‐jun Wang, Ping Ji, Ziming Li, Lei Jiao, Ying Wang, Shun Lu

Cancer Sci. 2022 Mar; 113(3): 838–851. Published online 2022 Jan 19. doi: 10.1111/cas.15243

PMCID:: PMC8898729

Abstract Article PDF–3.0M

Select item 82622233.

Somatic Mutation of NLRP Genes in Gastric and Colonic Cancers

Seong Won Moon, Hyun Ji Son, Ha Yoon Mo, Nam Jin Yoo, Sug Hyung Lee

Pathol Oncol Res. 2021; 27: 607385. Published online 2021 Apr 16. doi: 10.3389/pore.2021.607385

PMCID:: PMC8262223

Abstract Article PDF–1.8M

Select item 57884934.

The intracellular microbial sensor NLRP4 directs Rho-actin signaling to facilitate Group A Streptococcus-containing autophagosome-like vacuole formation

Takashi Nozawa, Chihiro Aikawa, Atsuko Minowa-Nozawa, Ichiro Nakagawa

Autophagy. 2017; 13(11): 1841–1854. Published online 2017 Nov 3. doi: 10.1080/15548627.2017.1358343

PMCID:: PMC5788493

Abstract Article PDF–1.6M

Select item 50365275.

Panorama of ancient metazoan macromolecular complexes

Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Nature. Author manuscript; available in PMC 2016 Sep 26.

Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877

PMCID:: PMC5036527

Abstract Article PDF–4.7M

Select item 45835466.

DYRK2 Negatively Regulates Type I Interferon Induction by Promoting TBK1 Degradation via Ser527 Phosphorylation

Tai An, Shu Li, Wei Pan, Po Tien, Bo Zhong, Hong-Bing Shu, Shuwen Wu

PLoS Pathog. 2015 Sep; 11(9): e1005179. Published online 2015 Sep 25. doi: 10.1371/journal.ppat.1005179

PMCID:: PMC4583546

Abstract Article PDF–2.5M

Select item 43156557.

Intrinsic flexibility of NLRP pyrin domains is a key factor in their conformational dynamics, fold stability, and dimerization

Roland G Huber, Clarissa Eibl, Julian E Fuchs

Protein Sci. 2015 Feb; 24(2): 174–181. Published online 2014 Dec 26. doi: 10.1002/pro.2601

PMCID:: PMC4315655

Abstract Article PDF–441K

Select item 43114038.

The CLRX.1/NOD24 (NLRP2P) Pseudogene Codes a Functional Negative Regulator of NF-κB, Pyrin-only Protein 4 (POP4)

Kristen A. Porter, Ellen B. Duffy, Patricia Nyland, Maninjay K. Atianand, Hamayun J. Sharifi, Jonathan A. Harton

Genes Immun. Author manuscript; available in PMC 2015 Jan 30.

Published in final edited form as: Genes Immun. 2014 Sep; 15(6): 392–403. Published online 2014 May 29. doi: 10.1038/gene.2014.30

PMCID:: PMC4311403

Abstract Article PDF–2.5M

Select item 37601619.

NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4

Jun Cui, Yinyin Li, Liang Zhu, Dan Liu, Zhou Songyang, Helen Y Wang, Rong-Fu Wang

Nat Immunol. Author manuscript; available in PMC 2013 Sep 3.

Published in final edited form as: Nat Immunol. 2012 Mar 4; 13(4): 387–395. Published online 2012 Mar 4. doi: 10.1038/ni.2239

PMCID:: PMC3760161

Abstract Article PDF–2.9M

Select item 345558210.

Isolation and Expression Analysis of the Human RNH2 Gene Encoding Ribonuclease Inhibitor 2

Toshinobu Miyamoto, Shiga Hasuike

J Assist Reprod Genet. 2002 Aug; 19(8): 394–397. doi: 10.1023/A:1016302706156

PMCID:: PMC3455582

Summary PDF–362K

Select item 344504611.

Structural and Functional Analysis of the NLRP4 Pyrin Domain

Clarissa Eibl, Simina Grigoriu, Manuel Hessenberger, Julia Wenger, Sandra Puehringer, Anderson S. Pinheiro, Roland N. Wagner, Martina Proell, John C. Reed, Rebecca Page, Kay Diederichs, Wolfgang Peti

Biochemistry. 2012 Sep 18; 51(37): 7330–7341. Published online 2012 Aug 28. doi: 10.1021/bi3007059