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Items: 1 to 20 of 48

1.
Structural basis for GSDMB pore formation and its targeting by IpaH7.8
Chengliang Wang, Sonia Shivcharan, Tian Tian, Skylar Wright, Danyang Ma, JengYih Chang, Kunpeng Li, Kangkang Song, Chen Xu, Vijay A. Rathinam, Jianbin Ruan
Nature. 2023; 616(7957): 590–597. Published online 2023 Mar 29. doi: 10.1038/s41586-023-05832-z
PMCID:
PMC10115629
AbstractArticlePDF–49M
2.
The study of GSDMB in pathogenesis of psoriasis vulgaris
Xiaojuan Ji, Huaqing Chen, Ling Xie, Shiqi Chen, Shan Huang, Qi Tan, Huifang Yang, Tao Yang, Xiaoying Ye, Zhaolin Zeng, Chunlei Wan, Longnian Li
PLoS One. 2023; 18(1): e0279908. Published online 2023 Jan 6. doi: 10.1371/journal.pone.0279908
PMCID:
PMC9821418
AbstractArticlePDF–963K
3.
Insights into the GSDMB-mediated cellular lysis and its targeting by IpaH7.8
Hang Yin, Jian Zheng, Qiuqiu He, Xuan Zhang, Xuzichao Li, Yongjian Ma, Xiao Liang, Jiaqi Gao, Benjamin L. Kocsis, Zhuang Li, Xiang Liu, Neal M. Alto, Long Li, Heng Zhang
Nat Commun. 2023; 14: 61. Published online 2023 Jan 4. doi: 10.1038/s41467-022-35725-0
PMCID:
PMC9813358
AbstractArticlePDF–2.8M
4.
GSDM gene polymorphisms regulate the IgE level in asthmatic patients
Amer Imraish, Tuqa Abu-Thiab, Tareq Alhindi, Malek Zihlif
PLoS One. 2022; 17(10): e0274951. Published online 2022 Oct 6. doi: 10.1371/journal.pone.0274951
PMCID:
PMC9536611
AbstractArticlePDF–401K
5.
GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis
Nitish Rana, Giuseppe Privitera, Hannah C. Kondolf, Katarzyna Bulek, Susana Lechuga, Carlo De Salvo, Daniele Corridoni, Agne Antanaviciute, Rebecca L. Maywald, Alexander M. Hurtado, Junjie Zhao, Emina H. Huang, Xiaoxia Li, E. Ricky Chan, Alison Simmons, Giorgos Bamias, Derek W. Abbott, Jason D. Heaney, Andrei I. Ivanov, Theresa T. Pizarro
Cell. Author manuscript; available in PMC 2023 Jan 20.
Published in final edited form as: Cell. 2022 Jan 20; 185(2): 283–298.e17. Published online 2022 Jan 11. doi: 10.1016/j.cell.2021.12.024
Correction in:
Cell. 2024 Feb 15; 187(4): 1011–1015.
PMCID:
PMC8879997
AbstractArticlePDF–4.8M
6.
Upregulated GSDMB in Clear Cell Renal Cell Carcinoma Is Associated with Immune Infiltrates and Poor Prognosis
Yuanshan Cui, Zhongbao Zhou, Yumeng Chai, Yong Zhang
J Immunol Res. 2021; 2021: 7753553. Published online 2021 Dec 16. doi: 10.1155/2021/7753553
PMCID:
PMC8702340
AbstractArticlePDF–4.7M
7.
The GSDMB rs7216389 SNP is associated with chronic rhinosinusitis in a multi-institutional cohort.
Dana E. Zack, Debra A. Stern, Amanda L. Willis, Alexander S. Kim, Corinne J. Mansfield, Danielle R. Reed, Steven G. Brooks, Nithin D. Adappa, James N. Palmer, Noam A. Cohen, Alexander G. Chiu, Brian H. Song, Chris H. Le, Eugene H. Chang
Int Forum Allergy Rhinol. Author manuscript; available in PMC 2022 Dec 1.
Published in final edited form as: Int Forum Allergy Rhinol. 2021 Dec; 11(12): 1647–1653. Published online 2021 Jun 2. doi: 10.1002/alr.22824
PMCID:
PMC8636513
AbstractArticlePDF–327K
8.
USP24-GSDMB complex promotes bladder cancer proliferation via activation of the STAT3 pathway
Haiqing He, Lu Yi, Bin Zhang, Bin Yan, Ming Xiao, Jiannan Ren, Dong Zi, Liang Zhu, Zhaohui Zhong, Xiaokun Zhao, Xin Jin, Wei Xiong
Int J Biol Sci. 2021; 17(10): 2417–2429. Published online 2021 Jun 11. doi: 10.7150/ijbs.54442
PMCID:
PMC8315027
AbstractArticlePDF–3.3M
9.
Pathogenic Ubiquitination of GSDMB Inhibits NK-cell Bactericidal Functions.
Justin M. Hansen, Maarten F. de Jong, Qi Wu, Li-Shu Zhang, David B. Heisler, Laura T. Alto, Neal M. Alto
Cell. Author manuscript; available in PMC 2022 Jun 10.
Published in final edited form as: Cell. 2021 Jun 10; 184(12): 3178–3191.e18. Published online 2021 May 21. doi: 10.1016/j.cell.2021.04.036
PMCID:
PMC8221529
AbstractArticlePDF–2.0M
10.
Household mold exposure interacts with inflammation-related genetic variants on childhood asthma: a case–control study
Yu Zhang, Li Hua, Quan-Hua Liu, Shu-Yuan Chu, Yue-Xin Gan, Min Wu, Yi-Xiao Bao, Qian Chen, Jun Zhang
BMC Pulm Med. 2021; 21: 114. Published online 2021 Apr 2. doi: 10.1186/s12890-021-01484-9
PMCID:
PMC8019181
AbstractArticlePDF–838K
11.
Genetic analyses identify GSDMB associated with asthma severity, exacerbations, and antiviral pathways
Xingnan Li, Stephanie A. Christenson, Brian Modena, Huashi Li, William W. Busse, Mario Castro, Loren C. Denlinger, Serpil C. Erzurum, John V. Fahy, Benjamin Gaston, Annette T. Hastie, Elliot Israel, Nizar N. Jarjour, Bruce D. Levy, Wendy C. Moore, Prescott G. Woodruff, Naftali Kaminski, Sally E. Wenzel, Eugene R. Bleecker, Deborah A. Meyers
J Allergy Clin Immunol. Author manuscript; available in PMC 2022 Mar 1.
Published in final edited form as: J Allergy Clin Immunol. 2021 Mar; 147(3): 894–909. Published online 2020 Aug 11. doi: 10.1016/j.jaci.2020.07.030
PMCID:
PMC7876167
AbstractArticlePDF–807K
12.
GSDMB promotes non-canonical pyroptosis by enhancing caspase-4 activity
Qin Chen, Peiliang Shi, Yufang Wang, Dayuan Zou, Xiuwen Wu, Dingyu Wang, Qiongyuan Hu, Yujie Zou, Zan Huang, Jianan Ren, Zhaoyu Lin, Xiang Gao
J Mol Cell Biol. 2019 Jun; 11(6): 496–508. Published online 2018 Oct 15. doi: 10.1093/jmcb/mjy056
PMCID:
PMC6734491
AbstractArticlePDF–1.2M
13.
A functional splicing variant associated with decreased asthma risk abolishes the ability of gasdermin B (GSMDB) to induce epithelial cell pyroptosis
Ronald A. Panganiban, Maoyun Sun, Amber Dahlin, Hae-Ryung Park, Mengyuan Kan, Blanca E. Himes, Jennifer A. Mitchel, Carlos Iribarren, Eric Jorgenson, Scott H. Randell, Elliot Israel, Kelan Tantisira, Stephanie Shore, Jin-Ah Park, Scott T. Weiss, Ann Chen Wu, Quan Lu
J Allergy Clin Immunol. Author manuscript; available in PMC 2018 Nov 9.
Published in final edited form as: J Allergy Clin Immunol. 2018 Nov; 142(5): 1469–1478.e2. Published online 2018 Jan 9. doi: 10.1016/j.jaci.2017.11.040
PMCID:
PMC6037620
AbstractArticlePDF–1.3M
14.
The role of local CpG DNA methylation in mediating the 17q21 asthma-susceptibility GSDMB/ORMDL3 expression quantitative trait locus
Parul H. Kothari, Weiliang Qiu, Damien C. Croteau-Chonka, Fernando D. Martinez, Andrew H. Liu, Robert F. Lemanske, Jr., Carole Ober, Jerry A. Krishnan, Dan L. Nicolae, Kathleen C. Barnes, Stephanie J. London, Albino Barraza-Villarreal, Steven R. White, Edward T. Naureckas, Joshua Millstein, W. James Gauderman, Frank D. Gilliland, Vincent J. Carey, Scott T. Weiss, Benjamin A. Raby, On behalf of the Asthma BioRepository for Integrative Genomic Exploration (Asthma BRIDGE) Consortium
J Allergy Clin Immunol. Author manuscript; available in PMC 2019 Jun 1.
Published in final edited form as: J Allergy Clin Immunol. 2018 Jun; 141(6): 2282–2286.e6. Published online 2018 Jan 31. doi: 10.1016/j.jaci.2017.11.057
PMCID:
PMC5994185
ArticlePDF–215K
15.
Identification of the functional variant driving ORMDL3 and GSDMB expression in human chromosome 17q12-21 in primary biliary cholangitis
Yuki Hitomi, Kaname Kojima, Minae Kawashima, Yosuke Kawai, Nao Nishida, Yoshihiro Aiba, Michio Yasunami, Masao Nagasaki, Minoru Nakamura, Katsushi Tokunaga
Sci Rep. 2017; 7: 2904. Published online 2017 Jun 6. doi: 10.1038/s41598-017-03067-3
PMCID:
PMC5460198
AbstractArticlePDF–1.7M
16.
The Characterization of GSDMB Splicing and Backsplicing Profiles Identifies Novel Isoforms and a Circular RNA That Are Dysregulated in Multiple Sclerosis
Giulia Cardamone, Elvezia Maria Paraboschi, Valeria Rimoldi, Stefano Duga, Giulia Soldà, Rosanna Asselta
Int J Mol Sci. 2017 Mar; 18(3): 576. Published online 2017 Mar 7. doi: 10.3390/ijms18030576
PMCID:
PMC5372592
AbstractArticlePDF–1.4M
17.
Analysis of rs8067378 Polymorphism in the Risk of Uterine Cervical Cancer from a Polish Population and its Impact on Gasdermin B Expression
Anna Lutkowska, Andrzej Roszak, Margarita Lianeri, Anna Sowińska, Emianka Sotiri, Pawel P. Jagodziński
Mol Diagn Ther. 2017; 21(2): 199–207. Published online 2017 Jan 25. doi: 10.1007/s40291-017-0256-1
PMCID:
PMC5355524
AbstractArticlePDF–470K
18.
Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein
Kinlin L. Chao, Liudmila Kulakova, Osnat Herzberg
Proc Natl Acad Sci U S A. 2017 Feb 14; 114(7): E1128–E1137. Published online 2017 Feb 1. doi: 10.1073/pnas.1616783114
PMCID:
PMC5321033
AbstractArticlePDF–2.1M
19.
Gasdermin B expression predicts poor clinical outcome in HER2-positive breast cancer
Marta Hergueta-Redondo, David Sarrio, Ángela Molina-Crespo, Rocío Vicario, Cristina Bernadó-Morales, Lidia Martínez, Alejandro Rojo-Sebastián, Jordi Serra-Musach, Alba Mota, Ángel Martínez-Ramírez, Maria Ángeles Castilla, Antonio González-Martin, Sonia Pernas, Amparo Cano, Javier Cortes, Paolo G. Nuciforo, Vicente Peg, José Palacios, Miguel Ángel Pujana, Joaquín Arribas, Gema Moreno-Bueno
Oncotarget. 2016 Aug 30; 7(35): 56295–56308. Published online 2016 Jul 22. doi: 10.18632/oncotarget.10787
PMCID:
PMC5302915
AbstractArticlePDF–6.8M
20.
GSDMB induces an asthma phenotype characterized by increased airway responsiveness and remodeling without lung inflammation
Sudipta Das, Marina Miller, Andrew K. Beppu, James Mueller, Matthew D. McGeough, Christine Vuong, Maya R. Karta, Peter Rosenthal, Fazila Chouiali, Taylor A. Doherty, Richard C. Kurten, Qutayba Hamid, Hal M. Hoffman, David H. Broide
Proc Natl Acad Sci U S A. 2016 Nov 15; 113(46): 13132–13137. Published online 2016 Oct 31. doi: 10.1073/pnas.1610433113
PMCID:
PMC5135378
AbstractArticlePDF–1.0M

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