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Items: 1 to 20 of 53

1.
Highly Conserved C-Terminal Region of Indian Hedgehog N-Fragment Contributes to Its Auto-Processing and Multimer Formation
Xiaoqing Wang, Hao Liu, Yanfang Liu, Gefei Han, Yushu Wang, Haifeng Chen, Lin He, Gang Ma
Biomolecules. 2021 Jun; 11(6): 792. Published online 2021 May 25. doi: 10.3390/biom11060792
PMCID:
PMC8227148
AbstractArticlePDF–2.7M
2.
Hedgehog inhibitor decreases chemosensitivity to 5‐fluorouracil and gemcitabine under hypoxic conditions in pancreatic cancer
Hideya Onishi, Yoshihiro Morifuji, Masaya Kai, Kumi Suyama, Hironori Iwasaki, Mitsuo Katano
Cancer Sci. 2012 Jul; 103(7): 1272–1279. Published online 2012 May 17. doi: 10.1111/j.1349-7006.2012.02297.x
PMCID:
PMC7659296
AbstractArticlePDF–686K
3.
HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells
Uma Thanigai Arasu, Ashik Jawahar Deen, Sanna Pasonen-Seppänen, Sami Heikkinen, Maciej Lalowski, Riikka Kärnä, Kai Härkönen, Petri Mäkinen, Elisa Lázaro-Ibáñez, Pia R-M Siljander, Sanna Oikari, Anna-Liisa Levonen, Kirsi Rilla
Cell Mol Life Sci. 2020 Oct; 77(20): 4093–4115. Published online 2019 Dec 9. doi: 10.1007/s00018-019-03399-5
PMCID:
PMC7532973
AbstractArticlePDF–9.1M
4.
Indian Hedgehog regulates senescence in bone marrow-derived mesenchymal stem cell through modulation of ROS/mTOR/4EBP1, p70S6K1/2 pathway
Mahmoud Al-Azab, Bing Wang, Abdalkhalig Elkhider, Williams Walana, Weiping Li, Bo Yuan, Yunshan Ye, Yawei Tang, Marwan Almoiliqy, Salah Adlat, Jing Wei, Yan Zhang, Xia Li
Aging (Albany NY) 2020 Apr 15; 12(7): 5693–5715. Published online 2020 Apr 1. doi: 10.18632/aging.102958
PMCID:
PMC7185126
AbstractArticlePDF–4.2M
5.
A novel variant of IHH in a Chinese family with brachydactyly type 1
Qi Yang, Jin Wang, Xiaoxian Tian, Fei Shen, Jing Lan, Qiang Zhang, Xin Fan, Shang Yi, Mengting Li, Yiping Shen
BMC Med Genet. 2020; 21: 60. Published online 2020 Mar 24. doi: 10.1186/s12881-020-01000-6
PMCID:
PMC7092535
AbstractArticlePDF–1.0M
6.
The Roles of Indian Hedgehog Signaling in TMJ Formation
Till E. Bechtold, Naito Kurio, Hyun-Duck Nah, Cheri Saunders, Paul C. Billings, Eiki Koyama
Int J Mol Sci. 2019 Dec; 20(24): 6300. Published online 2019 Dec 13. doi: 10.3390/ijms20246300
PMCID:
PMC6941023
AbstractArticlePDF–7.4M
7.
Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells
Evelyne Lima-Fernandes, Alex Murison, Tiago da Silva Medina, Yadong Wang, Anqi Ma, Cherry Leung, Genna M. Luciani, Jennifer Haynes, Aaron Pollett, Constanze Zeller, Shili Duan, Antonija Kreso, Dalia Barsyte-Lovejoy, Bradly G. Wouters, Jian Jin, Daniel D. De Carvalho, Mathieu Lupien, Cheryl H. Arrowsmith, Catherine A. O’Brien
Nat Commun. 2019; 10: 1436. Published online 2019 Mar 29. doi: 10.1038/s41467-019-09309-4
PMCID:
PMC6441108
AbstractArticlePDF–1.9M
8.
p.E95K mutation in Indian hedgehog causing brachydactyly type A1 impairs IHH/Gli1 downstream transcriptional regulation
Lu Shen, Gang Ma, Ye Shi, Yunfeng Ruan, Xuhan Yang, Xi Wu, Yuyu Xiong, Chunling Wan, Chao Yang, Lei Cai, Likuan Xiong, Xueli Gong, Lin He, Shengying Qin
BMC Genet. 2019; 20: 10. Published online 2019 Jan 16. doi: 10.1186/s12863-018-0697-5
PMCID:
PMC6335781
AbstractArticlePDF–790K
9.
Basal cell carcinoma pathogenesis and therapy involving hedgehog signaling and beyond
Anshika Bakshi, Sandeep C. Chaudhary, Mehtab Rana, Craig A. Elmets, Mohammad Athar
Mol Carcinog. Author manuscript; available in PMC 2018 May 21.
Published in final edited form as: Mol Carcinog. 2017 Dec; 56(12): 2543–2557. Published online 2017 Aug 22. doi: 10.1002/mc.22690
PMCID:
PMC5962346
AbstractArticlePDF–686K
10.
Gorlin syndrome-derived induced pluripotent stem cells are hypersensitive to hedgehog-mediated osteogenic induction
Daigo Hasegawa, Hiromi Ochiai-Shino, Shoko Onodera, Takashi Nakamura, Akiko Saito, Takeshi Onda, Katsuhito Watanabe, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, Kenjiro Kosaki, Akira Yamaguchi, Takahiko Shibahara, Toshifumi Azuma
PLoS One. 2017; 12(10): e0186879. Published online 2017 Oct 31. doi: 10.1371/journal.pone.0186879
PMCID:
PMC5663396
AbstractArticlePDF–9.2M
11.
Association of chloride intracellular channel 4 and Indian hedgehog proteins with survival of patients with pancreatic ductal adenocarcinoma
Qiong Zou, Zhulin Yang, Daiqiang Li, Ziru Liu, Yuan yuan
Int J Exp Pathol. 2016 Dec; 97(6): 422–429. Published online 2017 Feb 16. doi: 10.1111/iep.12213
PMCID:
PMC5370235
AbstractArticlePDF–741K
12.
The Annexin a2 Promotes Development in Arthritis through Neovascularization by Amplification Hedgehog Pathway
Jun Yi, Yan Zhu, Yin Jia, Hongdie Jiang, Xin Zheng, Dejing Liu, Shunxiang Gao, Mingjuan Sun, Bo Hu, Binghua Jiao, Lianghua Wang, Kaihui Wang
PLoS One. 2016; 11(3): e0150363. Published online 2016 Mar 10. doi: 10.1371/journal.pone.0150363
PMCID:
PMC4786284
AbstractArticlePDF–4.9M
13.
Hedgehog signalling does not stimulate cartilage catabolism and is inhibited by Interleukin-1β
Clare L. Thompson, Riana Patel, Terri-Ann N. Kelly, Angus K. T. Wann, Clark T. Hung, J. Paul Chapple, Martin M. Knight
Arthritis Res Ther. 2015; 17: 373. Published online 2015 Dec 24. doi: 10.1186/s13075-015-0891-z
PMCID:
PMC4718026
AbstractArticlePDF–1.1M
14.
Celiac Disease Histopathology Recapitulates Hedgehog Downregulation, Consistent with Wound Healing Processes Activation
Stefania Senger, Anna Sapone, Maria Rosaria Fiorentino, Giuseppe Mazzarella, Gregory Y. Lauwers, Alessio Fasano
PLoS One. 2015; 10(12): e0144634. Published online 2015 Dec 9. doi: 10.1371/journal.pone.0144634
PMCID:
PMC4674131
AbstractArticlePDF–3.4M
15.
Indian hedgehog signaling triggers Nkx3.2 protein degradation during chondrocyte maturation
Seung-Won Choi, Da-Un Jeong, Jeong-Ah Kim, Boyoung Lee, Kyu Sang Joeng, Fanxin Long, Dae-Won Kim
Biochem J. Author manuscript; available in PMC 2015 Feb 19.
Published in final edited form as: Biochem J. 2012 May 1; 443(3): 789–798. doi: 10.1042/BJ20112062
PMCID:
PMC4334119
AbstractArticlePDF–757K
16.
A new role for Hedgehogs in juxtacrine signaling
Christopher A. Pettigrew, Eva Asp, Charles P. Emerson, Jr.
Mech Dev. Author manuscript; available in PMC 2015 Feb 1.
Published in final edited form as: Mech Dev. 2014 Feb; 131: 137–149. Published online 2013 Dec 14. doi: 10.1016/j.mod.2013.12.002
PMCID:
PMC4220416
AbstractArticlePDF–1.1M
17.
Indian Hedgehog in Synovial Fluid Is a Novel Marker for Early Cartilage Lesions in Human Knee Joint
Congming Zhang, Xiaochun Wei, Chongwei Chen, Kun Cao, Yongping Li, Qiang Jiao, Juan Ding, Jingming Zhou, Braden C. Fleming, Qian Chen, Xianwen Shang, Lei Wei
Int J Mol Sci. 2014 May; 15(5): 7250–7265. Published online 2014 Apr 28. doi: 10.3390/ijms15057250
PMCID:
PMC4057670
AbstractArticlePDF–1.3M
18.
Intra-articular Injection of Human Mesenchymal Stem Cells (MSCs) Promote Rat Meniscal Regeneration by Being Activated to Express Indian Hedgehog that Enhances Expression of Type II Collagen
Masafumi Horie, Hosoon Choi, Ryang Hwa Lee, Roxanne L. Reger, Joni Ylostalo, Takeshi Muneta, I chiro Sekiya, Darwin J. Prockop
Osteoarthritis Cartilage. Author manuscript; available in PMC 2013 Oct 2.
Published in final edited form as: Osteoarthritis Cartilage. 2012 Oct; 20(10): 1197–1207. Published online 2012 Jun 29. doi: 10.1016/j.joca.2012.06.002
PMCID:
PMC3788634
AbstractArticlePDF–2.2M
19.
Hedgehog signaling regulates hypoxia induced epithelial to mesenchymal transition and invasion in pancreatic cancer cells via a ligand-independent manner
Jianjun Lei, Jiguang Ma, Qingyong Ma, Xuqi Li, Han Liu, Qinhong Xu, Wanxing Duan, Qing Sun, Jun Xu, Zheng Wu, Erxi Wu
Mol Cancer. 2013; 12: 66. Published online 2013 Jun 20. doi: 10.1186/1476-4598-12-66
PMCID:
PMC3699387
AbstractArticlePDF–1.9M
20.
Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors
Antonio Jimeno, Glen J. Weiss, Wilson H. Miller, Jr, Scott Gettinger, Bernard J.C. Eigl, Anne Lynne S. Chang, Joi Dunbar, Shannon Devens, Kerrie Faia, Georgios Skliris, Jeff Kutok, Karl D. Lewis, Raoul Tibes, William H. Sharfman, Robert W. Ross, Charles M. Rudin
Clin Cancer Res. Author manuscript; available in PMC 2013 Jun 27.
Published in final edited form as: Clin Cancer Res. 2013 May 15; 19(10): 2766–2774. Published online 2013 Apr 10. doi: 10.1158/1078-0432.CCR-12-3654
PMCID:
PMC3694426
AbstractArticlePDF–868K

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