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Select item 101649601.

Kidney allograft rejection is associated with an imbalance of B cells, regulatory T cells and differentiated CD28-CD8+ T cells: analysis of a cohort of 1095 graft biopsies

Hoa Le Mai, Nicolas Degauque, Marine Lorent, Marie Rimbert, Karine Renaudin, Richard Danger, Clarisse Kerleau, Gaelle Tilly, Anaïs Vivet, Sabine Le Bot, Florent Delbos, Alexandre Walencik, Magali Giral, Sophie Brouard

Front Immunol. 2023; 14: 1151127. Published online 2023 Apr 24. doi: 10.3389/fimmu.2023.1151127

PMCID:: PMC10164960

Abstract Article PDF–410K

Select item 101383562.

Genome-Wide Meta-Analysis Identifies Multiple Novel Rare Variants to Predict Common Human Infectious Diseases Risk

Andrea Gelemanović, Tatjana Ćatipović Ardalić, Ajka Pribisalić, Caroline Hayward, Ivana Kolčić, Ozren Polašek

Int J Mol Sci. 2023 Apr; 24(8): 7006. Published online 2023 Apr 10. doi: 10.3390/ijms24087006

PMCID:: PMC10138356

Abstract Article PDF–825K

Select item 94843243.

Specific transcriptional programs differentiate ICOS from CD28 costimulatory signaling in human Naïve CD4⁺ T cells

Casimiro Luca Gigliotti, Elena Boggio, Francesco Favero, Danny Incarnato, Claudio Santoro, Salvatore Oliviero, Josè Maria Rojo, Silvia Zucchelli, Francesca Persichetti, Gianluca Baldanzi, Umberto Dianzani, Davide Corà

Front Immunol. 2022; 13: 915963. Published online 2022 Sep 5. doi: 10.3389/fimmu.2022.915963

PMCID:: PMC9484324

Abstract Article PDF–2.4M

Select item 91273714.

Assembly of nuclear dimers of PI3K regulatory subunits is regulated by the Cdc42-activated tyrosine kinase ACK

Natasha S. Clayton, Millie Fox, Jose J. Vicenté-Garcia, Courtney M. Schroeder, Trevor D. Littlewood, Jonathon I. Wilde, Kadalmani Krishnan, Murray J.B. Brown, Claire Crafter, Helen R. Mott, Darerca Owen

J Biol Chem. 2022 Jun; 298(6): 101916. Published online 2022 Apr 13. doi: 10.1016/j.jbc.2022.101916

PMCID:: PMC9127371

Abstract Article PDF–2.6M

Select item 91130915.

COPD is associated with increased pro-inflammatory CD28null CD8 T and NKT-like cells in the small airways

Greg Hodge, Hubertus Jersmann, Hai B Tran, Patrick F Asare, Minnu Jayapal, Paul N Reynolds, Mark Holmes, Sandra Hodge

Clin Exp Immunol. 2022 Mar; 207(3): 351–359. Published online 2022 Jan 3. doi: 10.1093/cei/uxab037

PMCID:: PMC9113091

Abstract Article PDF–850K

Select item 87482526.

Clinicopathological significance of CD28 overexpression in adult T‐cell leukemia/lymphoma

Yuma Sakamoto, Takashi Ishida, Ayako Masaki, Morishige Takeshita, Hiromi Iwasaki, Kentaro Yonekura, Yukie Tashiro, Asahi Ito, Shigeru Kusumoto, Shinsuke Iida, Atae Utsunomiya, Ryuzo Ueda, Hiroshi Inagaki

Cancer Sci. 2022 Jan; 113(1): 349–361. Published online 2021 Nov 29. doi: 10.1111/cas.15191

PMCID:: PMC8748252

Abstract Article PDF–1.5M

Select item 87412897.

Mice transgenic for human CTLA4-CD28 fusion gene show proliferation and transformation of ATLL-like and AITL-like T cells

Gyu Jin Lee, Yukyung Jun, Yoon Kyung Jeon, Daekee Lee, Sanghyuk Lee, Jaesang Kim

Oncoimmunology. 2022; 11(1): 2015170. Published online 2022 Jan 4. doi: 10.1080/2162402X.2021.2015170

PMCID:: PMC8741289

Abstract Article PDF–6.5M

Select item 83764148.

Cryptic association of B7‐2 molecules and its implication for clustering

Swetha Lankipalli, Mahadeva Swamy H S, Deepak Selvam, Dibyendu Samanta, Deepak Nair, Udupi A. Ramagopal

Protein Sci. 2021 Sep; 30(9): 1958–1973. Published online 2021 Jul 10. doi: 10.1002/pro.4151

PMCID:: PMC8376414

Abstract Article PDF–3.1M

Select item 83298419.

Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy

Vivien Béziat, Franck Rapaport, Jiafen Hu, Matthias Titeux, Mathilde Bonnet des Claustres, Mathieu Bourgey, Heather Griffin, Élise Bandet, Cindy S. Ma, Roya Sherkat, Hassan Rokni-Zadeh, David M. Louis, Majid Changi-Ashtiani, Ottavia M. Delmonte, Toshiaki Fukushima, Tanwir Habib, Andrea Guennoun, Taushif Khan, Noemi Bender, Mahbuba Rahman, Frédégonde About, Rui Yang, Geetha Rao, Claire Rouzaud, Jingwei Li, Debra Shearer, Karla Balogh, Fatima Al Ali, Manar Ata, Soroosh Dabiri, Mana Momenilandi, Justine Nammour, Marie-Alexandra Alyanakian, Marianne Leruez-Ville, David Guenat, Marie Materna, Léa Marcot, Natasha Vladikine, Christine Soret, Hassan Vahidnezhad, Leila Youssefian, Amir Hossein Saeidian, Jouni Uitto, Émilie Catherinot, Shadi Sadat Navabi, Mohammed Zarhrate, David T. Woodley, Mohamed Jeljeli, Thomas Abraham, Serkan Belkaya, Lazaro Lorenzo, Jérémie Rosain, Mousa Bayat, Fanny Lanternier, Olivier Lortholary, Faramarz Zakavi, Philippe Gros, Gérard Orth, Laurent Abel, Jean-Luc Prétet, Sylvie Fraitag, Emmanuelle Jouanguy, Mark M. Davis, Stuart G. Tangye, Luigi D. Notarangelo, Nico Marr, Tim Waterboer, David Langlais, John Doorbar, Alain Hovnanian, Neil Christensen, Xavier Bossuyt, Mohammad Shahrooei, Jean-Laurent Casanova

Cell. Author manuscript; available in PMC 2022 Jul 8.

Published in final edited form as: Cell. 2021 Jul 8; 184(14): 3812–3828.e30. Published online 2021 Jul 1. doi: 10.1016/j.cell.2021.06.004

PMCID:: PMC8329841

Abstract Article PDF–3.7M

Select item 820655410.

Association of Polymorphisms in T-Cell Activation Costimulatory/Inhibitory Signal Genes With Allograft Kidney Rejection Risk

Jose Luis Santiago, Luis Sánchez-Pérez, Isabel Pérez-Flores, Maria Angeles Moreno de la Higuera, Natividad Calvo Romero, Javier Querol-García, Elena Urcelay, Ana Isabel Sánchez-Fructuoso

Front Immunol. 2021; 12: 650979. Published online 2021 Jun 2. doi: 10.3389/fimmu.2021.650979

PMCID:: PMC8206554

Abstract Article PDF–444K

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 807567212.

CD28 Genetic Variants Increase Susceptibility to Diabetic Kidney Disease in Chinese Patients with Type 2 Diabetes: A Cross-Sectional Case Control Study

Yangyang Li, Li Jin, Jing Yan, Hong Zhang, Rong Zhang, Cheng Hu

Mediators Inflamm. 2021; 2021: 5521050. Published online 2021 Apr 17. doi: 10.1155/2021/5521050

PMCID:: PMC8075672

Abstract Article PDF–840K

Select item 800316213.

Beta-1,3 Oligoglucans Specifically Bind to Immune Receptor CD28 and May Enhance T Cell Activation

Jeffrey Comer, Molly Bassette, Riley Burghart, Mayme Loyd, Susumu Ishiguro, Ettayapuram Ramaprasad Azhagiya Singam, Ariela Vergara-Jaque, Ayaka Nakashima, Kengo Suzuki, Brian V. Geisbrecht, Masaaki Tamura

Int J Mol Sci. 2021 Mar; 22(6): 3124. Published online 2021 Mar 18. doi: 10.3390/ijms22063124

PMCID:: PMC8003162

Abstract Article PDF–2.5M

Select item 789431014.

Clinical significance of CD28 gene‐related activating alterations in adult T‐cell leukaemia/lymphoma

Yuma Sakamoto, Takashi Ishida, Ayako Masaki, Morishige Takeshita, Hiromi Iwasaki, Kentaro Yonekura, Yukie Tashiro, Asahi Ito, Shigeru Kusumoto, Atae Utsunomiya, Shinsuke Iida, Ryuzo Ueda, Hiroshi Inagaki

Br J Haematol. 2021 Jan; 192(2): 281–291. Published online 2020 Nov 18. doi: 10.1111/bjh.17211

PMCID:: PMC7894310

Abstract Article PDF–964K

Select item 775319615.

CD86 Is a Selective CD28 Ligand Supporting FoxP3+ Regulatory T Cell Homeostasis in the Presence of High Levels of CTLA-4

Neil Halliday, Cayman Williams, Alan Kennedy, Erin Waters, Anne M. Pesenacker, Blagoje Soskic, Claudia Hinze, Tie Zheng Hou, Behzad Rowshanravan, Daniel Janman, Lucy S. K. Walker, David M. Sansom

Front Immunol. 2020; 11: 600000. Published online 2020 Dec 8. doi: 10.3389/fimmu.2020.600000

PMCID:: PMC7753196

Abstract Article PDF–3.0M

Select item 769137416.

4-1BB Signaling Boosts the Anti-Tumor Activity of CD28-Incorporated 2^nd Generation Chimeric Antigen Receptor-Modified T Cells

Qiang Dai, Ping Han, Xinyue Qi, Fanlin Li, Min Li, Lilv Fan, Huihui Zhang, Xiaoqing Zhang, Xuanming Yang

Front Immunol. 2020; 11: 539654. Published online 2020 Nov 13. doi: 10.3389/fimmu.2020.539654

PMCID:: PMC7691374

Abstract Article PDF–934K

Select item 766730017.

Chromosome 2q33genetic polymorphisms in Tunisian endemic pemphigus foliaceus

Olfa Abida, Emna Bahloul, Mariem Ben Jmaa, Khadija Sellami, Ferjani Zouidi, Raouia Fakhfakh, Nadia Mahfoudh, Hamida Turki, Hatem Masmoudi

Mol Genet Genomic Med. 2020 Nov; 8(11): e1476. Published online 2020 Sep 1. doi: 10.1002/mgg3.1476

PMCID:: PMC7667300

Abstract Article PDF–709K

Select item 759242918.

CD28 Autonomous Signaling Orchestrates IL-22 Expression and IL-22-Regulated Epithelial Barrier Functions in Human T Lymphocytes

Martina Kunkl, Carola Amormino, Simone Frascolla, Manolo Sambucci, Marco De Bardi, Silvana Caristi, Stefano Arcieri, Luca Battistini, Loretta Tuosto

Front Immunol. 2020; 11: 590964. Published online 2020 Oct 14. doi: 10.3389/fimmu.2020.590964

PMCID:: PMC7592429

Abstract Article PDF–1.4M

Select item 751013119.

The role of CD28 in the prognosis of young lung adenocarcinoma patients

Dantong Sun, Lu Tian, Tiantian Bian, Han Zhao, Junyan Tao, Lizong Feng, Qiaoling Liu, Helei Hou

BMC Cancer. 2020; 20: 910. Published online 2020 Sep 23. doi: 10.1186/s12885-020-07412-0

PMCID:: PMC7510131

Abstract Article PDF–4.6M

Select item 745512020.

CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation

Kathryn E. Beckermann, Rachel Hongo, Xiang Ye, Kirsten Young, Katie Carbonell, Diana C. Contreras Healey, Peter J. Siska, Sierra Barone, Caroline E. Roe, Christof C. Smith, Benjamin G. Vincent, Frank M. Mason, Jonathan M. Irish, W. Kimryn Rathmell, Jeffrey C. Rathmell

JCI Insight. 2020 Aug 20; 5(16): e138729. Published online 2020 Aug 20. doi: 10.1172/jci.insight.138729

PMCID:: PMC7455120

Abstract Article PDF–9.2M

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