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Items: 1 to 20 of 179

1.
CRL4DCAF1/VprBP E3 ubiquitin ligase controls ribosome biogenesis, cell proliferation, and development
Xiao-Ran Han, Naoya Sasaki, Sarah C. Jackson, Pu Wang, Zhijun Li, Matthew D. Smith, Ling Xie, Xian Chen, Yanping Zhang, William F. Marzluff, Yue Xiong
Sci Adv. 2020 Dec; 6(51): eabd6078. Published online 2020 Dec 18. doi: 10.1126/sciadv.abd6078
PMCID:
PMC11206221
AbstractArticlePDF–2.7M
2.
DCAF1 interacts with PARD3 to promote hepatocellular carcinoma progression and metastasis by activating the Akt signaling pathway
Jinyao Zhang, Yuze Shi, Ke Ding, Weiwei Yu, Jianbo He, Beicheng Sun
J Exp Clin Cancer Res. 2024; 43: 136. Published online 2024 May 6. doi: 10.1186/s13046-024-03055-2
PMCID:
PMC11071249
AbstractArticlePDF–6.7M
3.
Comparative interactome analysis of α-arrestin families in human and Drosophila
Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam
eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328
PMCID:
PMC10945707
AbstractArticlePDF–2.8M
4.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
5.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
6.
S100 Calcium Binding Protein A16 Promotes Cell Proliferation by triggering LATS1 ubiquitin degradation mediated by CUL4A ligase to inhibit Hippo pathway in Glioma development
Yifang Hu, Rihua Zhang, Shan Lu, Wensong Zhang, Dan Wang, Yaoqi Ge, Feng Jiang, Xiaoxuan Qin, Yun Liu
Int J Biol Sci. 2023; 19(7): 2034–2052. Published online 2023 Apr 2. doi: 10.7150/ijbs.79924
PMCID:
PMC10158029
AbstractArticlePDF–7.9M
7.
Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer
Nikhil B. Ghate, Sungmin Kim, Yonghwan Shin, Jinman Kim, Michael Doche, Scott Valena, Alan Situ, Sangnam Kim, Suhn K. Rhie, Heinz-Josef Lenz, Tobias S. Ulmer, Shannon M. Mumenthaler, Woojin An
Nat Commun. 2023; 14: 2140. Published online 2023 Apr 17. doi: 10.1038/s41467-023-37883-1
PMCID:
PMC10110550
AbstractArticlePDF–2.0M
8.
Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy
Jingjie Yi, Omid Tavana, Huan Li, Donglai Wang, Richard J. Baer, Wei Gu
Nat Commun. 2023; 14: 1941. Published online 2023 Apr 6. doi: 10.1038/s41467-023-37617-3
PMCID:
PMC10079682
AbstractArticlePDF–3.3M
9.
CircVPRBP inhibits nodal metastasis of cervical cancer by impeding RACK1 O-GlcNAcylation and stability
Chunyu Zhang, Hongye Jiang, Li Yuan, Yuandong Liao, Pan Liu, Qiqiao Du, Chaoyun Pan, Tianyu Liu, Jie Li, Yili Chen, Jiaming Huang, Yanchun Liang, Meng Xia, Manman Xu, Shuhang Qin, Qiaojian Zou, Yunyun Liu, Hua Huang, Yuwen Pan, Jiaying Li, Junxiu Liu, Wei Wang, Shuzhong Yao
Oncogene. 2023; 42(11): 793–807. Published online 2023 Jan 19. doi: 10.1038/s41388-023-02595-9
PMCID:
PMC10005957
AbstractArticlePDF–10M
10.
The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain
Lisa Marie Weber, Yulin Jia, Bastian Stielow, Stephen S Gisselbrecht, Yinghua Cao, Yanpeng Ren, Iris Rohner, Jessica King, Elisabeth Rothman, Sabrina Fischer, Clara Simon, Ignasi Forné, Andrea Nist, Thorsten Stiewe, Martha L Bulyk, Zhanxin Wang, Robert Liefke
Nucleic Acids Res. 2023 Jan 25; 51(2): 574–594. Published online 2022 Dec 20. doi: 10.1093/nar/gkac1188
PMCID:
PMC9881136
AbstractArticlePDF–4.4M
11.
A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth
Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841
PMCID:
PMC9769698
AbstractArticlePDF–2.7M
12.
Insight into Viral Hijacking of CRL4 Ubiquitin Ligase through Structural Analysis of the pUL145-DDB1 Complex
Elizaveta T. Wick, Colton J. Treadway, Zhijun Li, Nathan I. Nicely, Zhizhong Ren, Albert S. Baldwin, Yue Xiong, Joseph S. Harrison, Nicholas G. Brown
J Virol. 2022 Sep; 96(17): e00826-22. Published online 2022 Aug 8. doi: 10.1128/jvi.00826-22
PMCID:
PMC9472758
AbstractArticlePDF–3.2M
13.
Isoform-specific and ubiquitination dependent recruitment of Tet1 to replicating heterochromatin modulates methylcytosine oxidation
María Arroyo, Florian D. Hastert, Andreas Zhadan, Florian Schelter, Susanne Zimbelmann, Cathia Rausch, Anne K. Ludwig, Thomas Carell, M. Cristina Cardoso
Nat Commun. 2022; 13: 5173. Published online 2022 Sep 2. doi: 10.1038/s41467-022-32799-8
Correction in:
Nat Commun. 2023; 14: 369.
PMCID:
PMC9440122
AbstractArticlePDF–9.3M
14.
VPRBP Functions Downstream of the Androgen Receptor and OGT to Restrict p53 Activation in Prostate Cancer
Ninu Poulose, Nicholas Forsythe, Adam Polonski, Gemma Gregg, Sarah Maguire, Marc Fuchs, Sarah Minner, Guido Sauter, Simon S. McDade, Ian G. Mills
Mol Cancer Res. 2022 Jul 6; 20(7): 1047–1060. Published online 2022 Mar 29. doi: 10.1158/1541-7786.MCR-21-0477
PMCID:
PMC9381113
AbstractArticlePDF–2.0M
15.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
16.
Stabilization of SAMHD1 by NONO is crucial for Ara-C resistance in AML
Feifei Zhang, Jun Sun, Xiaofeng Tang, Yiping Liang, Quanhui Jiao, Bo Yu, Zhengzai Dai, Xuhui Yuan, Jiayu Li, Jinhua Yan, Zhiping Zhang, Song Fan, Min Wang, Haiyan Hu, Changhua Zhang, Xiao-Bin Lv
Cell Death Dis. 2022 Jul; 13(7): 590. Published online 2022 Jul 8. doi: 10.1038/s41419-022-05023-0
PMCID:
PMC9270467
AbstractArticlePDF–3.6M
17.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
18.
Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling
Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser
Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151
PMCID:
PMC9105235
AbstractArticlePDF–5.8M
19.
A protein interaction landscape of breast cancer
Minkyu Kim, Jisoo Park, Mehdi Bouhaddou, Kyumin Kim, Ajda Rojc, Maya Modak, Margaret Soucheray, Michael J. McGregor, Patrick O’Leary, Denise Wolf, Erica Stevenson, Tzeh Keong Foo, Dominique Mitchell, Kari A. Herrington, Denise P. Muñoz, Beril Tutuncuoglu, Kuei-Ho Chen, Fan Zheng, Jason F. Kreisberg, Morgan E. Diolaiti, John D. Gordan, Jean-Philippe Coppé, Danielle L. Swaney, Bing Xia, Laura van ’t Veer, Alan Ashworth, Trey Ideker, Nevan Krogan
Science. Author manuscript; available in PMC 2022 Apr 26.
Published in final edited form as: Science. 2021 Oct; 374(6563): eabf3066. Published online 2021 Oct 1. doi: 10.1126/science.abf3066
PMCID:
PMC9040556
AbstractArticlePDF–2.2M
20.
WWP1 upregulation predicts poor prognosis and promotes tumor progression by regulating ubiquitination of NDFIP1 in intrahepatic cholangiocarcinoma
Yongjian Li, Qian Cheng, Jie Gao, Zhuomiaoyu Chen, Jingheng Guo, Zuyin Li, Lingyu Tian, Chao Zhang, Yuzi Li, Jiaxi Zheng, Zhao Li, Jiye Zhu
Cell Death Discov. 2022; 8: 107. Published online 2022 Mar 9. doi: 10.1038/s41420-022-00882-0
PMCID:
PMC8906119
AbstractArticlePDF–6.1M

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