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Select item 101855611.

RagD auto-activating mutations impair MiT/TFE activity in kidney tubulopathy and cardiomyopathy syndrome

Irene Sambri, Marco Ferniani, Giulia Campostrini, Marialuisa Testa, Viviana Meraviglia, Mariana E. G. de Araujo, Ladislav Dokládal, Claudia Vilardo, Jlenia Monfregola, Nicolina Zampelli, Francesca Del Vecchio Blanco, Annalaura Torella, Carolina Ruosi, Simona Fecarotta, Giancarlo Parenti, Leopoldo Staiano, Milena Bellin, Lukas A. Huber, Claudio De Virgilio, Francesco Trepiccione, Vincenzo Nigro, Andrea Ballabio

Nat Commun. 2023; 14: 2775. Published online 2023 May 15. doi: 10.1038/s41467-023-38428-2

PMCID:: PMC10185561

Abstract Article PDF–4.7M

Select item 101653582.

TFEB and TFE3 drive kidney cystogenesis and tumorigenesis

Chiara Di Malta, Angela Zampelli, Letizia Granieri, Claudia Vilardo, Rossella De Cegli, Laura Cinque, Edoardo Nusco, Salvatore Pece, Daniela Tosoni, Francesca Sanguedolce, Nicolina Cristina Sorrentino, Maria J Merino, Deborah Nielsen, Ramaprasad Srinivasan, Mark W Ball, Christopher J Ricketts, Cathy D Vocke, Martin Lang, Baktiar Karim, Luisa Lanfrancone, Laura S Schmidt, W Marston Linehan, Andrea Ballabio

EMBO Mol Med. 2023 May; 15(5): e16877. Published online 2023 Mar 29. doi: 10.15252/emmm.202216877

PMCID:: PMC10165358

Abstract Article PDF–5.8M

Select item 101415223.

TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy

Tanjing Song, Suli Lv, Xianyun Ma, Xuefeng Zhao, Li Fan, Qingli Zou, Neng Li, Yingying Yan, Wen Zhang, Lidong Sun

J Biol Chem. 2023 May; 299(5): 104621. Published online 2023 Mar 18. doi: 10.1016/j.jbc.2023.104621

PMCID:: PMC10141522

Abstract Article PDF–2.5M

Select item 99080114.

A central role for regulated protein stability in the control of TFE3 and MITF by nutrients

Christopher Nardone, Brad A. Palanski, Daniel C. Scott, Richard T. Timms, Karl W. Barber, Xin Gu, Aoyue Mao, Yumei Leng, Emma V. Watson, Brenda A. Schulman, Philip A. Cole, Stephen J. Elledge

Mol Cell. Author manuscript; available in PMC 2023 Feb 14.

Published in final edited form as: Mol Cell. 2023 Jan 5; 83(1): 57–73.e9. doi: 10.1016/j.molcel.2022.12.013

PMCID:: PMC9908011

Abstract Article PDF–2.9M

Select item 99011445.

p53 aberration and TFE3 gene amplification may be predictors of adverse prognosis in epithelioid angiomyolipoma of the kidney

Yanning Zhang, Xuejing Wei, Xiaojing Teng, Guangyong Chen

Diagn Pathol. 2023; 18: 14. Published online 2023 Feb 6. doi: 10.1186/s13000-023-01298-9

PMCID:: PMC9901144

Abstract Article PDF–2.5M

Select item 96739556.

TFEB- and TFE3-dependent autophagy activation supports cancer proliferation in the absence of centrosomes

Chien-Han Kao, Ting-Yu Su, Wei-Syun Huang, Xin-Ying Lu, Wann-Neng Jane, Chien-Yung Huang, Hung-Hsiang Huang, Won-Jing Wang

Autophagy. 2022; 18(12): 2830–2850. Published online 2022 Mar 22. doi: 10.1080/15548627.2022.2051880

PMCID:: PMC9673955

Abstract Article PDF–8.6M

Select item 92626147.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 90354528.

NUPR1 promotes the proliferation and metastasis of oral squamous cell carcinoma cells by activating TFE3-dependent autophagy

Tengfei Fan, Xiaoning Wang, Sheng Zhang, Ping Deng, Yi Jiang, Yidan Liang, Sheng Jie, Qing Wang, Chuwen Li, Guocai Tian, Zhen Zhang, Zhenhu Ren, Bo Li, Yanrong Chen, Zhijing He, Yan Luo, Mingliang Chen, Hanjiang Wu, Zhengping Yu, Huifeng Pi, Zhou Zhou, Zhiyuan Zhang

Signal Transduct Target Ther. 2022; 7: 130. Published online 2022 Apr 25. doi: 10.1038/s41392-022-00939-7

Correction in:: Signal Transduct Target Ther. 2022; 7: 321.

PMCID:: PMC9035452

Abstract Article PDF–5.7M

Select item 90290199.

Both SUMOylation and ubiquitination of TFE3 fusion protein regulated by androgen receptor are the potential target in the therapy of Xp11.2 translocation renal cell carcinoma

Ning Liu, Yi Chen, Lei Yang, Qiancheng Shi, Yanwen Lu, Wenliang Ma, Xiaodong Han, Hongqian Guo, Dongmei Li,, Weidong Gan,

Clin Transl Med. 2022 Apr; 12(4): e797. Published online 2022 Apr 22. doi: 10.1002/ctm2.797

PMCID:: PMC9029019

Abstract Article PDF–13M

Select item 882889510.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 869622611.

Transcription factor TFE3 enhances cell cycle and cancer progression by binding to the hTERT promoter

Beiping Miao, Chaoyang Zhang, Nadine Stroh, Lukas Brenner, Katrin Hufnagel, Jörg D. Hoheisel, Obul Reddy Bandapalli

Cancer Commun (Lond) 2021 Dec; 41(12): 1423–1426. Published online 2021 Sep 14. doi: 10.1002/cac2.12216

PMCID:: PMC8696226

Article PDF–505K

Select item 867155712.

Uterine PEComas: Correlation Between Melanocytic Marker Expression and TSC Alterations/TFE3 Fusions

Jennifer A. Bennett, Zehra Ordulu, Andre Pinto, Pankhuri Wanjari, Cristina R. Antonescu, Lauren L. Ritterhouse, Esther Oliva

Mod Pathol. Author manuscript; available in PMC 2022 Mar 31.

Published in final edited form as: Mod Pathol. 2022 Apr; 35(4): 515–523. Published online 2021 Jun 15. doi: 10.1038/s41379-021-00855-1

PMCID:: PMC8671557

Abstract Article PDF–2.3M

Select item 855290713.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 851658614.

TFE3 Regulates the Function of the Autophagy-Lysosome Pathway to Drive the Invasion and Metastasis of Papillary Thyroid Carcinoma

Hongsheng Lu, Chumeng Zhu, Yanyun Ruan, Lilong Fan, Kena Wei, Zhaohui Yang, Qi Chen

Anal Cell Pathol (Amst) 2021; 2021: 3081491. Published online 2021 Oct 7. doi: 10.1155/2021/3081491

PMCID:: PMC8516586

Abstract Article PDF–3.1M

Select item 849671815.

PRCC-TFE3 fusion-mediated PRKN/parkin-dependent mitophagy promotes cell survival and proliferation in PRCC-TFE3 translocation renal cell carcinoma

Bo Wang, Xiaoqin Yin, Weidong Gan, Fan Pan, Shiyuan Li, Zou Xiang, Xiaodong Han, Dongmei Li

Autophagy. 2021; 17(9): 2475–2493. Published online 2020 Oct 21. doi: 10.1080/15548627.2020.1831815

PMCID:: PMC8496718

Abstract Article PDF–22M

Select item 842137716.

Integrated exome and RNA sequencing of TFE3-translocation renal cell carcinoma

Guangxi Sun, Junru Chen, Jiayu Liang, Xiaoxue Yin, Mengni Zhang, Jin Yao, Ning He, Cameron M. Armstrong, Linmao Zheng, Xingming Zhang, Sha Zhu, Xiaomeng Sun, Xiaoxia Yang, Wanbin Zhao, Banghua Liao, Xiuyi Pan, Ling Nie, Ling Yang, Yuntian Chen, Jinge Zhao, Haoran Zhang, Jindong Dai, Yali Shen, Jiyan Liu, Rui Huang, Jiandong Liu, Zhipeng Wang, Yuchao Ni, Qiang Wei, Xiang Li, Qiao Zhou, Haojie Huang, Zhenhua Liu, Pengfei Shen, Ni Chen, Hao Zeng

Nat Commun. 2021; 12: 5262. Published online 2021 Sep 6. doi: 10.1038/s41467-021-25618-z

PMCID:: PMC8421377

Abstract Article PDF–2.7M

Select item 818498817.

Targeting of VPS18 by the lysosomotropic agent RDN reverses TFE3-mediated drug resistance

Huanmin Niu, Lilin Qian, Yanhai Luo, Fang Wang, Hongbo Zheng, Yanhui Gao, Hanbo Wang, Xuelei Hu, Huiqing Yuan, Hongxiang Lou

Signal Transduct Target Ther. 2021; 6: 224. Published online 2021 Jun 7. doi: 10.1038/s41392-021-00547-x

PMCID:: PMC8184988

Article PDF–1.3M

Select item 816503018.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 814379719.

TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex

Nicole Merritt, Keith Garcia, Dushyandi Rajendran, Zhen-Yuan Lin, Xiaomeng Zhang, Katrina A Mitchell, Nicholas Borcherding, Colleen Fullenkamp, Michael S Chimenti, Anne-Claude Gingras, Kieran F Harvey, Munir R Tanas

eLife. 2021; 10: e62857. Published online 2021 Apr 29. doi: 10.7554/eLife.62857

PMCID:: PMC8143797

Abstract Article PDF–4.5M

Select item 810310620.

Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1‐dependent TFEB/TFE3 regulation

Reini E N van der Welle, Rebekah Jobling, Christian Burns, Paolo Sanza, Jan A van der Beek, Alfonso Fasano, Lan Chen, Fried J Zwartkruis, Susan Zwakenberg, Edward F Griffin, Corlinda ten Brink, Tineke Veenendaal, Nalan Liv, Conny M A van Ravenswaaij‐Arts, Henny H Lemmink, Rolph Pfundt, Susan Blaser, Carolina Sepulveda, Andres M Lozano, Grace Yoon, Teresa Santiago‐Sim, Cedric S Asensio, Guy A Caldwell, Kim A Caldwell, David Chitayat, Judith Klumperman

EMBO Mol Med. 2021 May 7; 13(5): e13258. Published online 2021 Apr 14. doi: 10.15252/emmm.202013258

PMCID:: PMC8103106

Abstract Article PDF–4.0M

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Thiocapsa roseopersicina strain DSM 217, whole genome shotgun sequence
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gi|1225024635|ref|NZ_FNNZ01000074.1

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