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Select item 104135131.

CIS deletion by CRISPR/Cas9 enhances human primary natural killer cell functions against allogeneic glioblastoma

Tsutomu Nakazawa, Takayuki Morimoto, Ryosuke Maeoka, Ryosuke Matsuda, Mitsutoshi Nakamura, Fumihiko Nishimura, Noriko Ouji, Shuichi Yamada, Ichiro Nakagawa, Young Soo Park, Toshihiro Ito, Hiroyuki Nakase, Takahiro Tsujimura

J Exp Clin Cancer Res. 2023; 42: 205. Published online 2023 Aug 10. doi: 10.1186/s13046-023-02770-6

PMCID:: PMC10413513

Abstract Article PDF–11M

Select item 103883782.

CISH impairs lysosomal function in activated T cells resulting in mitochondrial DNA release and inflammaging

Jun Jin, Yunmei Mu, Huimin Zhang, Ines Sturmlechner, Chenyao Wang, Rohit R. Jadhav, Qiong Xia, Cornelia M. Weyand, Jorg J. Goronzy

Nat Aging. Author manuscript; available in PMC 2023 Nov 1.

Published in final edited form as: Nat Aging. 2023 May; 3(5): 600–616. Published online 2023 Apr 17. doi: 10.1038/s43587-023-00399-w

PMCID:: PMC10388378

Abstract Article PDF–4.5M

Select item 94276003.

Association of genetic polymorphisms of CISH with the risk of pulmonary tuberculosis in Zahedan, Southeast Iran

Mohammad Naderi, Mohammad Hashemi, Abolhassan Safdari, Gholamreza Bahari, Mohsen Taheri

Braz J Infect Dis. 2016 Jul-Aug; 20(4): 379–383. Published online 2016 Jun 5. doi: 10.1016/j.bjid.2016.05.003

PMCID:: PMC9427600

Abstract Article PDF–1.8M

Select item 81988064.

Genetic Predisposition to the Mortality in Septic Shock Patients: From GWAS to the Identification of a Regulatory Variant Modulating the Activity of a CISH Enhancer

Florian Rosier, Audrey Brisebarre, Claire Dupuis, Sabrina Baaklini, Denis Puthier, Christine Brun, Lydie C. Pradel, Pascal Rihet, Didier Payen

Int J Mol Sci. 2021 Jun; 22(11): 5852. Published online 2021 May 29. doi: 10.3390/ijms22115852

PMCID:: PMC8198806

Abstract Article PDF–5.0M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 75057676.

MiR-944/CISH mediated inflammation via STAT3 is involved in oral cancer malignance by cigarette smoking

Hsuan-Yu Peng, Jenn-Ren Hsiao, Sung-Tau Chou, Yuan-Ming Hsu, Guan-Hsun Wu, Yi-Shing Shieh, Shine-Gwo Shiah

Neoplasia. 2020 Nov; 22(11): 554–565. Published online 2020 Sep 19. doi: 10.1016/j.neo.2020.08.005

PMCID:: PMC7505767

Abstract Article PDF–2.1M

Select item 72019187.

NK cell–derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS

Cynthia Louis, Fernando Souza- Fonseca-Guimaraes, Yuyan Yang, Damian D’Silva, Tobias Kratina, Laura Dagley, Soroor Hediyeh-Zadeh, Jai Rautela, Seth Lucian Masters, Melissa J. Davis, Jeffrey J. Babon, Bogoljub Ciric, Eric Vivier, Warren S. Alexander, Nicholas D. Huntington, Ian P. Wicks

J Exp Med. 2020 May 4; 217(5): e20191421. Published online 2020 Feb 25. doi: 10.1084/jem.20191421

Correction in:: J Exp Med. 2020 May 4; 217(5): e2019142103192020c.

PMCID:: PMC7201918

Abstract Article PDF–5.0M

Select item 71536958.

ARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection

Ruth Hüttenhain, Jiewei Xu, Lily A. Burton, David E. Gordon, Judd F. Hultquist, Jeffrey R. Johnson, Laura Satkamp, Joseph Hiatt, David Y. Rhee, Kheewoong Baek, David C. Crosby, Alan D. Frankel, Alexander Marson, J. Wade Harper, Arno F. Alpi, Brenda A. Schulman, John D. Gross, Nevan J. Krogan

Cell Host Microbe. Author manuscript; available in PMC 2020 Jul 10.

Published in final edited form as: Cell Host Microbe. 2019 Jul 10; 26(1): 86–99.e7. Published online 2019 Jun 25. doi: 10.1016/j.chom.2019.05.008

PMCID:: PMC7153695

Abstract Article PDF–2.6M

Select item 69812069.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS^G13D

Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch

Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9

PMCID:: PMC6981206

Abstract Article PDF–3.7M

Select item 615681410.

Genetic contribution of suppressor of cytokine signalling polymorphisms to the susceptibility to infection after traumatic injury

A. Zhang, W. Gu, H. Lu, L. Zeng, L. Zhang, D. Du, J. Hao, D. Wen, X. Wang, J. Jiang

Clin Exp Immunol. 2018 Oct; 194(1): 93–102. Published online 2018 Sep 9. doi: 10.1111/cei.13160

PMCID:: PMC6156814

Abstract Article PDF–281K

Select item 587187211.

The Cish SH2 domain is essential for PLC-γ1 regulation in TCR stimulated CD8⁺ T cells

Geoffrey Guittard, Ana Dios-Esponera, Douglas C. Palmer, Itoro Akpan, Valarie A. Barr, Asit Manna, Nicholas P. Restifo, Lawrence E. Samelson

Sci Rep. 2018; 8: 5336. Published online 2018 Mar 28. doi: 10.1038/s41598-018-23549-2

PMCID:: PMC5871872

Abstract Article PDF–2.5M

Select item 553161112.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 540652913.

Suppressors of cytokine signaling: Potential immune checkpoint molecules for cancer immunotherapy

Shunsuke Chikuma, Mitsuhiro Kanamori, Setsuko Mise‐Omata, Akihiko Yoshimura

Cancer Sci. 2017 Apr; 108(4): 574–580. Published online 2017 Apr 19. doi: 10.1111/cas.13194

PMCID:: PMC5406529

Abstract Article PDF–982K

Select item 461721114.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 438575215.

EXPRESSION OF SUPPRESSOR OF CYTOKINE SIGNALING (SOCS) GENES IN HUMAN ELDERLY AND ALZHEIMER’S DISEASE BRAINS AND HUMAN MICROGLIA

D.G. Walker, A. M. Whetzel, L-F Lue

Neuroscience. Author manuscript; available in PMC 2016 Aug 27.

Published in final edited form as: Neuroscience. 2015 Aug 27; 302: 121–137. Published online 2014 Oct 5. doi: 10.1016/j.neuroscience.2014.09.052

PMCID:: PMC4385752

Abstract Article PDF–2.8M

Select item 437354116.

Regulation of cytokine-inducible SH2-containing protein (CIS) by ubiquitination and Elongin B/C interaction

Philip J. Jensik, Lydia A. Arbogast

Mol Cell Endocrinol. Author manuscript; available in PMC 2016 Feb 5.

Published in final edited form as: Mol Cell Endocrinol. 2015 Feb 5; 401: 130–141. Published online 2014 Nov 4. doi: 10.1016/j.mce.2014.10.017

PMCID:: PMC4373541

Abstract Article PDF–4.0M

Select item 432682717.

Biophysical Studies on Interactions and Assembly of Full-size E3 Ubiquitin Ligase: SUPPRESSOR OF CYTOKINE SIGNALING 2 (SOCS2)-ELONGIN BC-CULLIN 5-RING BOX PROTEIN 2 (RBX2)

Emil Bulatov, Esther M. Martin, Sneha Chatterjee, Axel Knebel, Satoko Shimamura, Albert Konijnenberg, Clare Johnson, Nico Zinn, Paola Grandi, Frank Sobott, Alessio Ciulli

J Biol Chem. 2015 Feb 13; 290(7): 4178–4191. Published online 2014 Dec 11. doi: 10.1074/jbc.M114.616664