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Select item 103332881.

Mitogen activated protein kinase phosphatase 5 alleviates liver ischemia–reperfusion injury by inhibiting TAK1/JNK/p38 pathway

Qiwen Yu, Sanyang Chen, Jiye Li, Hongwei Tang, Jihua Shi, Wenzhi Guo, Shuijun Zhang

Sci Rep. 2023; 13: 11110. Published online 2023 Jul 10. doi: 10.1038/s41598-023-37768-9

PMCID:: PMC10333288

Abstract Article PDF–6.0M

Select item 87241342.

MAP Kinase Phosphatase-5 Deficiency Protects Against Pressure Overload-Induced Cardiac Fibrosis

Chao Zhong, Kisuk Min, Zhiqiang Zhao, Cheng Zhang, Erhe Gao, Yan Huang, Xinbo Zhang, Margaret Baldini, Rajika Roy, Xiaofeng Yang, Walter J. Koch, Anton M. Bennett, Jun Yu

Front Immunol. 2021; 12: 790511. Published online 2021 Dec 21. doi: 10.3389/fimmu.2021.790511

PMCID:: PMC8724134

Abstract Article PDF–7.5M

Select item 86662813.

Bone marrow macrophage‐derived exosomal miR‐143‐5p contributes to insulin resistance in hepatocytes by repressing MKP5

Linfang Li, Huiyan Zuo, Xiuqing Huang, Tao Shen, Weiqing Tang, Xiaoyi Zhang, Tong An, Lin Dou, Jian Li

Cell Prolif. 2021 Dec; 54(12): e13140. Published online 2021 Oct 14. doi: 10.1111/cpr.13140

PMCID:: PMC8666281

Abstract Article PDF–2.0M

Select item 86175004.

De novo germline mutation in the dual specificity phosphatase 10 gene accelerates autoimmune diabetes

Anne-Perrine Foray, Sophie Candon, Sara Hildebrand, Cindy Marquet, Fabrice Valette, Coralie Pecquet, Sebastien Lemoine, Francina Langa-Vives, Michael Dumas, Peipei Hu, Pere Santamaria, Sylvaine You, Stephen Lyon, Lindsay Scott, Chun Hui Bu, Tao Wang, Darui Xu, Eva Marie Y. Moresco, Claudio Scazzocchio, Jean-François Bach, Bruce Beutler, Lucienne Chatenoud

Proc Natl Acad Sci U S A. 2021 Nov 23; 118(47): e2112032118. Published online 2021 Nov 15. doi: 10.1073/pnas.2112032118

PMCID:: PMC8617500

Abstract Article PDF–1.2M

Select item 83157385.

RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons

Chaomei Xiang, Karla K. Frietze, Yingtao Bi, Yanwen Li, Valentina Dal Pozzo, Sharmistha Pal, Noah Alexander, Valerie Baubet, Victoria D’Acunto, Christopher E. Mason, Ramana V. Davuluri, Nadia Dahmane

Mol Cell Biol. 2021 Jul; 41(7): e00526-20. Prepublished online 2021 Apr 26. Published online 2021 Jun 23. doi: 10.1128/MCB.00526-20

PMCID:: PMC8315738

Abstract Article PDF–7.7M

Select item 75829376.

MKP-5 Relieves Lipotoxicity-Induced Islet β-Cell Dysfunction and Apoptosis via Regulation of Autophagy

Tongjian Zhao, Jie Ma, Lulu Li, Wenjing Teng, Yafei Tian, Yongjun Ma, Wei Wang, Weiqun Yan, Ping Jiao

Int J Mol Sci. 2020 Oct; 21(19): 7161. Published online 2020 Sep 28. doi: 10.3390/ijms21197161

PMCID:: PMC7582937

Abstract Article PDF–5.6M

Select item 75694887.

An allosteric site on MKP5 reveals a strategy for small molecule inhibition

Zachary T. K. Gannam, Kisuk Min, Shanelle R. Shillingford, Lei Zhang, James Herrington, Laura Abriola, Peter C. Gareiss, Georgios Pantouris, Argyrios Tzouvelekis, Naftali Kaminski, Xinbo Zhang, Jun Yu, Haya Jamali, Jonathan A. Ellman, Elias Lolis, Karen S. Anderson, Anton M. Bennett

Sci Signal. Author manuscript; available in PMC 2020 Oct 19.

Published in final edited form as: Sci Signal. 2020 Aug 25; 13(646): eaba3043. Published online 2020 Aug 25. doi: 10.1126/scisignal.aba3043

PMCID:: PMC7569488

Abstract Article PDF–3.1M

Select item 70982948.

The Role of MKP-5 in Adipocyte-Macrophage Interactions during Obesity

Yuanhua Lu, Jie Ma, Jianan Zhao, Zhuoyao Song, Chao Zhou, Xiu Liu, Wenjing Teng, Wei Wang, Qi Zhang, Weiqun Yan, Ping Jiao

Obes Facts. 2020 Feb; 13(1): 86–101. Published online 2020 Jan 21. doi: 10.1159/000505343

PMCID:: PMC7098294

Abstract Article PDF–1.0M

Select item 68799009.

Role of dual-specificity protein phosphatase DUSP10/MKP-5 in pulmonary fibrosis

Nikos Xylourgidis, Kisuk Min, Farida Ahangari, Guoying Yu, Jose D. Herazo-Maya, Theodoros Karampitsakos, Vassilis Aidinis, Leonhard Binzenhöfer, Demosthenes Bouros, Anton M. Bennett, Naftali Kaminski, Argyrios Tzouvelekis

Am J Physiol Lung Cell Mol Physiol. 2019 Nov 1; 317(5): L678–L689. Published online 2019 Sep 4. doi: 10.1152/ajplung.00264.2018

PMCID:: PMC6879900

Abstract Article

Select item 646478610.

Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss

Adelaida M Celaya, Isabel Sánchez-Pérez, Jose M Bermúdez-Muñoz, Lourdes Rodríguez-de la Rosa, Laura Pintado-Berninches, Rosario Perona, Silvia Murillo-Cuesta, Isabel Varela-Nieto

eLife. 2019; 8: e39159. Published online 2019 Apr 2. doi: 10.7554/eLife.39159

PMCID:: PMC6464786

Abstract Article PDF–5.9M

Select item 581317811.

Colorectal Cancer-Associated Genes Are Associated with Tooth Agenesis and May Have a Role in Tooth Development

Meredith A. Williams, Claudia Biguetti, Miguel Romero-Bustillos, Kanwal Maheshwari, Nuriye Dinckan, Franco Cavalla, Xiaoming Liu, Renato Silva, Sercan Akyalcin, Z. Oya Uyguner, Alexandre R. Vieira, Brad A. Amendt, Walid D. Fakhouri, Ariadne Letra

Sci Rep. 2018; 8: 2979. Published online 2018 Feb 14. doi: 10.1038/s41598-018-21368-z

PMCID:: PMC5813178

Abstract Article PDF–1.7M

Select item 564847812.

Loss of MKP-5 promotes myofiber survival by activating STAT3/Bcl-2 signaling during regenerative myogenesis

Kisuk Min, Ahmed Lawan, Anton M. Bennett

Skelet Muscle. 2017; 7: 21. Published online 2017 Oct 18. doi: 10.1186/s13395-017-0137-7

PMCID:: PMC5648478

Abstract Article PDF–1.7M

Select item 533974413.

A Phosphoproteomic Screen Identifies a Guanine Nucleotide Exchange Factor for Rab3A Protein as a Mitogen-activated Protein (MAP) Kinase Phosphatase-5-regulated MAP Kinase Target in Interleukin 6 (IL-6) Secretion and Myogenesis

Hojin Lee, Kisuk Min, Jae-Sung Yi, Hao Shi, Woochul Chang, Leandra Jackson, Anton M. Bennett

J Biol Chem. 2017 Mar 3; 292(9): 3581–3590. Published online 2017 Jan 17. doi: 10.1074/jbc.M116.769208

PMCID:: PMC5339744

Abstract Article PDF–2.2M

Select item 484486314.

Transcriptome of the inner circular smooth muscle of the developing mouse intestine: evidence for regulation of visceral smooth muscle genes by the Hedgehog target gene, cJun

Katherine Gurdziel, Kyle R. Vogt, Katherine D. Walton, Gary K. Schneider, Deborah L. Gumucio

Dev Dyn. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Dev Dyn. 2016 May; 245(5): 614–626. Published online 2016 Mar 17. doi: 10.1002/dvdy.24399

PMCID:: PMC4844863

Abstract Article PDF–2.1M

Select item 446343515.

Regulation of Adipose Tissue Inflammation and Insulin Resistance by MAPK Phosphatase 5

Yongliang Zhang, Thang Nguyen, Peng Tang, Norman J. Kennedy, Huipeng Jiao, Mingliang Zhang, Joseph M. Reynolds, Anja Jaeschke, Natalia Martin-Orozco, Yeonseok Chung, Wei-min He, Chen Wang, Weiping Jia, Baoxue Ge, Roger J. Davis, Richard A. Flavell, Chen Dong

J Biol Chem. 2015 Jun 12; 290(24): 14875–14883. Published online 2015 Apr 28. doi: 10.1074/jbc.M115.660969

PMCID:: PMC4463435

Abstract Article PDF–1.6M

Select item 445051216.

Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathways

Harish N Vasudevan, Pierre Mazot, Fenglei He, Philippe Soriano

eLife. 2015; 4: e07186. Published online 2015 May 7. doi: 10.7554/eLife.07186

PMCID:: PMC4450512

Abstract Article PDF–4.3M

Select item 385681117.

Beneficial innate signaling interference for antibacterial responses by a Toll-like receptor–mediated enhancement of the MKP-IRF3 axis

Hideo Negishi, Kosuke Matsuki, Nobuyasu Endo, Hana Sarashina, Shoji Miki, Atsushi Matsuda, Keiko Fukazawa, Naoko Taguchi-Atarashi, Hiroaki Ikushima, Hideyuki Yanai, Junko Nishio, Kenya Honda, Yoichiro Fujioka, Yusuke Ohba, Tetsuo Noda, Shun’ichiro Taniguchi, Eisuke Nishida, Yongliang Zhang, Hongbo Chi, Richard A. Flavell, Tadatsugu Taniguchi

Proc Natl Acad Sci U S A. 2013 Dec 3; 110(49): 19884–19889. Published online 2013 Nov 18. doi: 10.1073/pnas.1320145110

PMCID:: PMC3856811

Abstract Article PDF–1.0M

Select item 381794618.

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates

Jeremy A. Miller, Jason Nathanson, Daniel Franjic, Sungbo Shim, Rachel A. Dalley, Sheila Shapouri, Kimberly A. Smith, Susan M. Sunkin, Amy Bernard, Jeffrey L. Bennett, Chang-Kyu Lee, Michael J. Hawrylycz, Allan R. Jones, David G. Amaral, Nenad Sestan, Fred H. Gage, Ed S. Lein

Development. 2013 Nov 15; 140(22): 4633–4644. doi: 10.1242/dev.097212

PMCID:: PMC3817946

Abstract Article

Select item 374801219.

Dual-Specificity Phosphatase 10 Controls Brown Adipocyte Differentiation by Modulating the Phosphorylation of P38 Mitogen-Activated Protein Kinase

Hye-Ryung Choi, Won Kon Kim, Eun Young Kim, Baek Soo Han, Jeong-Ki Min, Seung-Wook Chi, Sung Goo Park, Kwang-Hee Bae, Sang Chul Lee

PLoS One. 2013; 8(8): e72340. Published online 2013 Aug 20. doi: 10.1371/journal.pone.0072340

PMCID:: PMC3748012

Abstract Article PDF–741K

Select item 371549520.

Pioglitazone Improves Reversal Learning and Exerts Mixed Cerebrovascular Effects in a Mouse Model of Alzheimer’s Disease with Combined Amyloid-β and Cerebrovascular Pathology

Panayiota Papadopoulos, Pedro Rosa-Neto, Joseph Rochford, Edith Hamel

PLoS One. 2013; 8(7): e68612. Published online 2013 Jul 18. doi: 10.1371/journal.pone.0068612

PMCID:: PMC3715495

Abstract Article PDF–2.0M

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