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Select item 91617691.

Essential role of Rnd1 in innate immunity during viral and bacterial infections

Akhilesh Kumar, Shalabh Mishra, Ashish Kumar, Ashwin Ashok Raut, Seiichi Sato, Akinori Takaoka, Himanshu Kumar

Cell Death Dis. 2022 Jun; 13(6): 520. Published online 2022 Jun 2. doi: 10.1038/s41419-022-04954-y

PMCID:: PMC9161769

Abstract Article PDF–4.3M

Select item 88040002.

Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration

Bhairavi Swaminathan, Seock-Won Youn, L. A. Naiche, Jing Du, Stephanie R. Villa, Jordan B. Metz, Huijuan Feng, Chaolin Zhang, Raphael Kopan, Peter A. Sims, Jan K. Kitajewski

Sci Rep. 2022; 12: 1655. Published online 2022 Jan 31. doi: 10.1038/s41598-022-05666-1

PMCID:: PMC8804000

Abstract Article PDF–8.1M

Select item 71699833.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 69186954.

Rnd Proteins Function as RhoA Antagonists by Activating p190 RhoGAP

Krister Wennerberg, Marie-Annick Forget, Shawn M. Ellerbroek, William T. Arthur, Keith Burridge, Jeffrey Settleman, Channing J. Der, Steen H. Hansen

Curr Biol. Author manuscript; available in PMC 2019 Dec 18.

Published in final edited form as: Curr Biol. 2003 Jul 1; 13(13): 1106–1115. doi: 10.1016/s0960-9822(03)00418-4

PMCID:: PMC6918695

Abstract Article PDF–1.8M

Select item 66961825.

The RND1 Small GTPase: Main Functions and Emerging Role in Oncogenesis

Laetitia Mouly, Julia Gilhodes, Anthony Lemarié, Elizabeth Cohen-Jonathan Moyal, Christine Toulas, Gilles Favre, Olivier Sordet, Sylvie Monferran

Int J Mol Sci. 2019 Aug; 20(15): 3612. Published online 2019 Jul 24. doi: 10.3390/ijms20153612

PMCID:: PMC6696182

Abstract Article PDF–3.2M

Select item 66186116.

A Multilevel Screening Strategy Defines a Molecular Fingerprint of Proregenerative Olfactory Ensheathing Cells and Identifies SCARB2, a Protein That Improves Regenerative Sprouting of Injured Sensory Spinal Axons

Kasper C. D. Roet, Elske H. P. Franssen, Frederik M. de Bree, Anke H. W. Essing, Sjirk-Jan J. Zijlstra, Nitish D. Fagoe, Hannah M. Eggink, Ruben Eggers, August B. Smit, Ronald E. van Kesteren, Joost Verhaagen

J Neurosci. 2013 Jul 3; 33(27): 11116–11135. doi: 10.1523/JNEUROSCI.1002-13.2013

PMCID:: PMC6618611

Abstract Article PDF–5.9M

Select item 59247617.

The Rho GTPase Rnd1 inhibits epithelial–mesenchymal transition in hepatocellular carcinoma and is a favorable anti-metastasis target

Cheng-Dong Qin, De-Ning Ma, Shi-Zhe Zhang, Ning Zhang, Zheng-Gang Ren, Xiao-Dong Zhu, Qing-An Jia, Zong-Tao Chai, Cheng-Hao Wang, Hui-Chuan Sun, Zhao-You Tang

Cell Death Dis. 2018 May; 9(5): 486. Published online 2018 Apr 30. doi: 10.1038/s41419-018-0517-x

PMCID:: PMC5924761

Abstract Article PDF–9.4M

Select item 56450868.

Analysis of the interaction of Plexin-B1 and Plexin-B2 with Rnd family proteins

Thomas Wylie, Ritu Garg, Anne J. Ridley, Maria R. Conte

PLoS One. 2017; 12(10): e0185899. Published online 2017 Oct 17. doi: 10.1371/journal.pone.0185899

PMCID:: PMC5645086

Abstract Article PDF–5.0M

Select item 51349979.

Modelling GTPase dynamics to understand RhoA-driven cancer cell invasion

Joseph H.R. Hetmanski, Jean-Marc Schwartz, Patrick T. Caswell

Biochem Soc Trans. 2016 Dec 15; 44(6): 1695–1700. Published online 2016 Dec 2. doi: 10.1042/BST20160184

PMCID:: PMC5134997

Abstract Article PDF–391K

Select item 437435310.

The Rho-GTPase Rnd1 Suppresses Mammary Tumorigenesis and EMT by Restraining Ras-MAPK signaling

Tomoyo Okada, Surajit Sinha, Ilaria Esposito, Gaia Schiavon, Miguel A. López-Lago, Wenjing Su, Christine A. Pratilas, Cristina Abele, Jonathan M. Hernandez, Masahiro Ohara, Morihito Okada, Agnes Viale, Adriana Heguy, Nicholas D. Socci, Anna Sapino, Venkatraman E. Seshan, Stephen Long, Giorgio Inghirami, Neal Rosen, Filippo G. Giancotti

Nat Cell Biol. Author manuscript; available in PMC 2015 Mar 26.

Published in final edited form as: Nat Cell Biol. 2015 Jan; 17(1): 81–94. Published online 2014 Dec 22. doi: 10.1038/ncb3082

Correction in:: Nat Cell Biol. 2019 Mar 6

PMCID:: PMC4374353

Abstract Article PDF–2.3M

Select item 363717611.

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

Pamela Sklar, Stephan Ripke, Laura J. Scott, Ole A. Andreassen, Sven Cichon, Nick Craddock, Howard J. Edenberg, John I. Nurnberger, Marcella Rietschel, Douglas Blackwood, Aiden Corvin, Matthew Flickinger, Weihua Guan, Morten Mattingsdal, Andrew Mcquillin, Phoenix Kwan, Thomas F. Wienker, Mark Daly, Frank Dudbridge, Peter A. Holmans, Danyu Lin, Margit Burmeister, Tiffany A. Greenwood, Marian L. Hamshere, Pierandrea Muglia, Erin N. Smith, Peter P. Zandi, Caroline M. Nievergelt, Rebecca Mckinney, Paul D. Shilling, Nicholas J. Schork, Cinnamon S. Bloss, Tatiana Foroud, Daniel L. Koller, Elliot S. Gershon, Chunyu Liu, Judith A. Badner, William A. Scheftner, William B. Lawson, Evaristus A. Nwulia, Maria Hipolito, William Coryell, John P. Rice, William Byerley, Francis J. McMahon, Thomas G. Schulze, Wade Berrettini, Falk W. Lohoff, James B. Potash, Pamela B. Mahon, Melvin G. Mcinnis, Sebastian Zöllner, Peng Zhang, David W. Craig, Szabocls Szelinger, Thomas B. Barrett, René Breuer, Sandra Meier, Jana Strohmaier, Stephanie H. Witt, Federica Tozzi, Anne Farmer, Peter McGuffin, John Strauss, Wei Xu, James L. Kennedy, John B. Vincent, Keith Matthews, Richard Day, Manuel D.C. Ferreira, Colm O'Dushlaine, Roy Perlis, Soumya Raychaudhuri, Douglas Ruderfer, Phil L. Hyoun, Jordan W. Smoller, Jun Li, Devin Absher, Robert C. Thompson, Fan Guo Meng, Alan F. Schatzberg, William E. Bunney, Jack D. Barchas, Edward G. Jones, Stanley J. Watson, Richard M. Myers, Huda Akil, Michael Boehnke, Kim Chambert, Jennifer Moran, Ed Scolnick, Srdjan Djurovic, Ingrid Melle, Gunnar Morken, Michael Gill, Derek Morris, Emma Quinn, Thomas W. Mühleisen, Franziska A. Degenhardt, Manuel Mattheisen, Johannes Schumacher, Wolfgang Maier, Michael Steffens, Peter Propping, Markus M. Nöthen, Adebayo Anjorin, Nick Bass, Hugh Gurling, Radhika Kandaswamy, Jacob Lawrence, Kevin Mcghee, Andrew Mcintosh, Alan W. Mclean, Walter J. Muir, Benjamin S. Pickard, Gerome Breen, David St Clair, Sian Caesar, Katherine Gordon-Smith, Lisa Jones, Christine Fraser, Elaine K. Green, Detelina Grozeva, Ian R. Jones, George Kirov, Valentina Moskvina, Ivan Nikolov, Michael C. O'Donovan, Michael J. Owen, David A. Collier, Amanda Elkin, Richard Williamson, Allan H. Young, I Nicol Ferrier, Kari Stefansson, Hreinn Stefansson, Porgeir Porgeirsson, Stacy Steinberg, Omar Gustafsson, Sarah E. Bergen, Vishwajit Nimgaonkar, Christina hultman, Mikael Landén, Paul Lichtenstein, Patrick Sullivan, Martin Schalling, Urban Osby, Lena Backlund, Louise Frisén, Niklas Langstrom, Stéphane Jamain, Marion Leboyer, Bruno Etain, Frank Bellivier, Hannes Petursson, Engilbert Sigur Sson, Bertram Müller-Mysok, Susanne Lucae, Markus Schwarz, Peter R. Schofield, Nick Martin, Grant W. Montgomery, Mark Lathrop, Högni Oskarsson, Michael Bauer, Adam Wright, Philip B. Mitchell, Martin Hautzinger, Andreas Reif, John R. Kelsoe, Shaun M. Purcell

Nat Genet. Author manuscript; available in PMC 2013 May 1.

Published in final edited form as: Nat Genet. 2011 Oct; 43(10): 977–983. Published online 2011 Sep 18. doi: 10.1038/ng.943

Correction in:: volume 44 on page 1072

PMCID:: PMC3637176

Abstract Article

Select item 344237612.

The GTPase-deficient Rnd Proteins Are Stabilized by Their Effectors

Liuh Ling Goh, Ed Manser

J Biol Chem. 2012 Sep 7; 287(37): 31311–31320. Published online 2012 Jul 17. doi: 10.1074/jbc.M111.327056

PMCID:: PMC3442376

Abstract Article PDF–2.2M

Select item 332731813.

Rnd1 and Rnd3 targeting to lipid raft is required for p190 RhoGAP activation

Izumi Oinuma, Kana Kawada, Kiyoka Tsukagoshi, Manabu Negishi

Mol Biol Cell. 2012 Apr 15; 23(8): 1593–1604. doi: 10.1091/mbc.E11-11-0900

PMCID:: PMC3327318

Abstract Article PDF–2.6M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 313825515.

Structural Basis of Rnd1 Binding to Plexin Rho GTPase Binding Domains (RBDs)

Hui Wang, Prasanta K. Hota, Yufeng Tong, Buren Li, Limin Shen, Lyudmila Nedyalkova, Susmita Borthakur, SoonJeung Kim, Wolfram Tempel, Matthias Buck, Hee-Won Park

J Biol Chem. 2011 Jul 22; 286(29): 26093–26106. Published online 2011 May 24. doi: 10.1074/jbc.M110.197053

PMCID:: PMC3138255

Abstract Article PDF–3.8M

Select item 300238516.

A Novel Testis-specific GTPase Serves as a Link to Proteasome Biogenesis: Functional Characterization of RhoS/RSA-14-44 in Spermatogenesis

Ning Zhang, Junbo Liang, Yongqiang Tian, Ligang Yuan, Lan Wu, Shiying Miao, Shudong Zong, Linfang Wang

Mol Biol Cell. 2010 Dec 15; 21(24): 4312–4324. doi: 10.1091/mbc.E10-04-0310

PMCID:: PMC3002385

Abstract Article PDF–2.9M

Select item 292829917.

The RhoA GEF Syx Is a Target of Rnd3 and Regulated via a Raf1-Like Ubiquitin-Related Domain

Liuh Ling Goh, Ed Manser

PLoS One. 2010; 5(8): e12409. Published online 2010 Aug 25. doi: 10.1371/journal.pone.0012409

PMCID:: PMC2928299

Abstract Article PDF–1.6M

Select item 279102418.

Structure and Function of the Intracellular Region of the Plexin-B1 Transmembrane Receptor

Yufeng Tong, Prasanta K. Hota, Junia Y. Penachioni, Mehdi B. Hamaneh, SoonJeung Kim, Rebecca S. Alviani, Limin Shen, Hao He, Wolfram Tempel, Luca Tamagnone, Hee-Won Park, Matthias Buck

J Biol Chem. 2009 Dec 18; 284(51): 35962–35972. Published online 2009 Oct 19. doi: 10.1074/jbc.M109.056275

PMCID:: PMC2791024

Abstract Article PDF–3.5M

Select item 270890119.

Rnd1 regulates axon extension by enhancing the microtubule destabilizing activity of SCG10.

Ying-Hua Li, Sharang Ghavampour, Percy Bondallaz, Lena Will, Gabriele Grenningloh, Andreas W. Püschel

J Biol Chem. 2009 Jun 5; 284(23): 16060. doi: 10.1074/jbc.A808126200

Corrects:: J Biol Chem, volume 284 on page 363

PMCID:: PMC2708901

Correction PDF–59K

Select item 265532120.

Binding of Rac1, Rnd1, and RhoD to a Novel Rho GTPase Interaction Motif Destabilizes Dimerization of the Plexin-B1 Effector Domain

Yufeng Tong, Preeti Chugha, Prasanta K. Hota, Rebecca S. Alviani, Mei Li, Wolfram Tempel, Limin Shen, Hee-Won Park, Matthias Buck

J Biol Chem. Author manuscript; available in PMC 2009 Mar 14.

Published in final edited form as: J Biol Chem. 2007 Dec 21; 282(51): 37215–37224. Published online 2007 Oct 4. doi: 10.1074/jbc.M703800200

PMCID:: PMC2655321

Abstract Article PDF–1.2M

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