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Select item 109729491.

SAP-expressing T peripheral helper cells identify systemic lupus erythematosus patients with lupus nephritis

Yevgeniya Gartshteyn, Laura Geraldino-Pardilla, Leila Khalili, Shoiab Bukhari, Shalom Lerrer, Robert J. Winchester, Anca D. Askanase, Adam Mor

Front Immunol. 2024; 15: 1327437. Published online 2024 Mar 14. doi: 10.3389/fimmu.2024.1327437

PMCID:: PMC10972949

Abstract Article PDF–5.3M

Select item 106556372.

Regulation of NKT cell development by SAP, the protein defective in XLP

Kim E Nichols, Jamie Hom, Shun-You Gong, Arupa Ganguly, Cindy S Ma, Jennifer L Cannons, Stuart G Tangye, Pamela L Schwartzberg, Gary A Koretzky, Paul L Stein

Nat Med. Author manuscript; available in PMC 2023 Nov 17.

Published in final edited form as: Nat Med. 2005 Mar; 11(3): 340–345. Published online 2005 Feb 13. doi: 10.1038/nm1189

PMCID:: PMC10655637

Abstract Article PDF–1.1M

Select item 105857623.

Overexpression of SH2D1A promotes cancer progression and is associated with immune cell infiltration in hepatocellular carcinoma via bioinformatics and in vitro study

Qian-Ming Xiang, Ni Jiang, Yue-Feng Liu, Yuan-Biao Wang, De-An Mu, Rong Liu, Lu-Yun Sun, Wei Zhang, Qiang Guo, Kai Li

BMC Cancer. 2023; 23: 1005. Published online 2023 Oct 19. doi: 10.1186/s12885-023-11315-1

PMCID:: PMC10585762

Abstract Article PDF–7.5M

Select item 100729064.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 92788905.

SAP interacts with CD28 to inhibit PD-1 signaling in T lymphocytes

Sabina Sandigursky, Mark Philips, Adam Mor

Clin Immunol. Author manuscript; available in PMC 2022 Jul 13.

Published in final edited form as: Clin Immunol. 2020 Aug; 217: 108485. Published online 2020 Jun 3. doi: 10.1016/j.clim.2020.108485

PMCID:: PMC9278890

Abstract Article PDF–953K

Select item 87210486.

Case Report: Meningoencephalitis With Thrombotic Occlusive Vasculopathy in a Young EBV-Naïve Boy Is Associated With a Novel SH2D1A Mutation

Jolanda Steininger, Raphael Rossmanith, Christoph B. Geier, Alexander Leiss-Piller, Lukas Thonhauser, Simone Weiss, Johannes A. Hainfellner, Michael Freilinger, Wolfgang M. Schmidt, Martha M. Eibl, Hermann M. Wolf

Front Immunol. 2021; 12: 747738. Published online 2021 Dec 20. doi: 10.3389/fimmu.2021.747738

PMCID:: PMC8721048

Abstract Article PDF–5.1M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80792198.

SLAM/SAP Decreased Follicular Regulatory T Cells in Patients with Graves' Disease

Lina Geng, Jun Yang, Xinyi Tang, Huiyong Peng, Jie Tian, Zhigang Hu, Yingzhao Liu, Huaxi Xu, Shengjun Wang

J Immunol Res. 2021; 2021: 5548463. Published online 2021 Apr 19. doi: 10.1155/2021/5548463

PMCID:: PMC8079219

Abstract Article PDF–1.4M

Select item 76115009.

Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis

Raffaella Meazza, Claudia Tuberosa, Valentina Cetica, Michela Falco, Silvia Parolini, Sam Grieve, Gillian M. Griffiths, Elena Sieni, Stefania Marcenaro, Concetta Micalizzi, Davide Montin, Franca Fagioli, Alessandro Moretta, Maria C. Mingari, Lorenzo Moretta, Luigi D. Notarangelo, Cristina Bottino, Maurizio Aricò, Daniela Pende

J Allergy Clin Immunol. Author manuscript; available in PMC 2021 Aug 16.

Published in final edited form as: J Allergy Clin Immunol. 2014 Dec 1; 134(6): 1381–1387.e7. Published online 2014 Jun 27. doi: 10.1016/j.jaci.2014.04.043

PMCID:: PMC7611500

Abstract Article PDF–2.6M

Select item 716998310.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 708667311.

Different Phenotypic Presentations of X-Linked Lymphoproliferative Disease in Siblings with Identical Mutations

Zohreh Nademi, Nesrine Radwan, Kanchan Rao, Kimberly Gilmour, Austen Worth, Claire Booth

J Clin Immunol. 2019; 39(5): 523–526. Published online 2019 May 29. doi: 10.1007/s10875-019-00649-w

PMCID:: PMC7086673

Article PDF–230K

Select item 696884312.

Functional characterization of NK cells in Mexican pediatric patients with acute lymphoblastic leukemia: Report from the Mexican Interinstitutional Group for the Identification of the Causes of Childhood Leukemia

Lucero Valenzuela-Vazquez, Juan Carlos Núñez-Enríquez, Jacqueline Sánchez-Herrera, Elva Jiménez-Hernández, Jorge Alfonso Martín-Trejo, Laura Eugenia Espinoza-Hernández, Aurora Medina-Sanson, Luz Victoria Flores-Villegas, José Gabriel Peñaloza-González, José Refugio Torres-Nava, Rosa Martha Espinosa-Elizondo, Raquel Amador-Sánchez, Jessica Denisse Santillán-Juárez, Janet Flores-Lujano, María Luisa Pérez-Saldívar, Luis Ramiro García-López, Alejandro Castañeda-Echevarría, Francisco Rodríguez-Leyva, Haydeé Rosas-Vargas, Minerva Mata-Rocha, David Aldebarán Duarte-Rodríguez, Omar Alejandro Sepúlveda-Robles, Ismael Mancilla-Herrera, Juan Manuel Mejía-Aranguré, Mario Ernesto Cruz-Munoz

PLoS One. 2020; 15(1): e0227314. Published online 2020 Jan 17. doi: 10.1371/journal.pone.0227314

PMCID:: PMC6968843

Abstract Article PDF–1.1M

Select item 616156413.

miR-126 Suppresses Invasion and Migration of Malignant Glioma by Targeting Mature T Cell Proliferation 1 (MTCP1)

Liangbo Han, Huaqiang Liu, Jinfeng Wu, Jinkai Liu

Med Sci Monit. 2018; 24: 6630–6637. Published online 2018 Sep 20. doi: 10.12659/MSM.910292

PMCID:: PMC6161564

Abstract Article PDF–1.5M

Select item 589794214.

Identification of a novel nonsense mutation in SH2D1A in a patient with X-linked lymphoproliferative syndrome type 1: a case report

Xiaodong Lyu, Zhen Guo, Yangwei Li, Ruihua Fan, Yongping Song

BMC Med Genet. 2018; 19: 60. Published online 2018 Apr 12. doi: 10.1186/s12881-018-0576-y

PMCID:: PMC5897942

Abstract Article PDF–2.2M

Select item 580548315.

T cells regulate peripheral naïve mature B cell survival by cell/cell contact mediated through SLAMF6 and SAP

Lihi Radomir, Sivan Cohen, Matthias P. Kramer, Eszter Bakos, Hadas Lewinsky, Avital Barak, Ziv Porat, Richard Bucala, Polina Stepensky, Shirly Becker-Herman, Idit Shachar

J Immunol. Author manuscript; available in PMC 2018 Oct 15.

Published in final edited form as: J Immunol. 2017 Oct 15; 199(8): 2745–2757. Published online 2017 Sep 13. doi: 10.4049/jimmunol.1700557

PMCID:: PMC5805483

Abstract Article PDF–1.0M

Select item 559563016.

Restimulation-induced T cell death through NTB-A/SAP signaling pathway is impaired in tuberculosis patients with depressed immune responses

Rodrigo E. Hernández Del Pino, Joaquín M. Pellegrini, Ana I. Rovetta, Delfina Peña, Guadalupe I. Álvarez, Agustín Rolandelli, Rosa M. Musella, Domingo J. Palmero, Alejandro Malbran, Virginia Pasquinelli, Verónica E. García

Immunol Cell Biol. Author manuscript; available in PMC 2017 Nov 26.

Published in final edited form as: Immunol Cell Biol. 2017 Sep; 95(8): 716–728. Published online 2017 May 26. doi: 10.1038/icb.2017.42

PMCID:: PMC5595630

Abstract Article PDF–1.4M

Select item 489390617.

Decreased SAP expression in T cells from patients with SLE contributes to early signaling abnormalities and reduced IL-2 production

Maria P. Karampetsou, Denis Comte, Katalin Kis-Toth, Cox Terhorst, Vasileios C. Kyttaris, George C. Tsokos

J Immunol. Author manuscript; available in PMC 2017 Jun 15.

Published in final edited form as: J Immunol. 2016 Jun 15; 196(12): 4915–4924. Published online 2016 May 11. doi: 10.4049/jimmunol.1501523

PMCID:: PMC4893906

Abstract Article PDF–2.8M

Select item 475819018.

Frequent Mutations in SH2D1A (XLP) in Males Presenting With High-Grade Mature B-Cell Neoplasms

J.T. Sandlund, S.A. Shurtleff, M. Onciu, E. Horwitz, W. Leung, V. Howard, R. Rencher, M.E. Conley

Pediatr Blood Cancer. Author manuscript; available in PMC 2016 Feb 18.

Published in final edited form as: Pediatr Blood Cancer. 2013 Sep; 60(9): E85–E87. Published online 2013 Apr 15. doi: 10.1002/pbc.24525

PMCID:: PMC4758190

Abstract Article PDF–69K

Select item 461062819.

A polymorphism in a phosphotyrosine signalling motif of CD229 (Ly9, SLAMF3) alters SH2 domain binding and T‐cell activation

Stefanie Margraf, Lee I. Garner, Timothy J. Wilson, Marion H. Brown

Immunology. 2015 Nov; 146(3): 392–400. Published online 2015 Sep 13. doi: 10.1111/imm.12513

PMCID:: PMC4610628

Abstract Article PDF–464K

Select item 444121520.

Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders

Nidhi Sahni, Song Yi, Mikko Taipale, Juan I. Fuxman Bass, Jasmin Coulombe-Huntington, Fan Yang, Jian Peng, Jochen Weile, Georgios I. Karras, Yang Wang, István A. Kovács, Atanas Kamburov, Irina Krykbaeva, Mandy H. Lam, George Tucker, Vikram Khurana, Amitabh Sharma, Yang-Yu Liu, Nozomu Yachie, Quan Zhong, Yun Shen, Alexandre Palagi, Adriana San-Miguel, Changyu Fan, Dawit Balcha, Amelie Dricot, Daniel M. Jordan, Jennifer M. Walsh, Akash A. Shah, Xinping Yang, Ani Stoyanova, Alex Leighton, Michael A. Calderwood, Yves Jacob, Michael E. Cusick, Kourosh Salehi-Ashtiani, Luke J. Whitesell, Shamil Sunyaev, Bonnie Berger, Albert-László Barabási, Benoit Charloteaux, David E. Hill, Tong Hao, Frederick P. Roth, Yu Xia, Albertha J.M. Walhout, Susan Lindquist, Marc Vidal

Cell. Author manuscript; available in PMC 2016 Apr 23.

Published in final edited form as: Cell. 2015 Apr 23; 161(3): 647–660. doi: 10.1016/j.cell.2015.04.013

PMCID:: PMC4441215

Abstract Article PDF–1.2M

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