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Select item 111581411.

Membrane sialidase NEU3 is highly expressed in human melanoma cells promoting cell growth with minimal changes in the composition of gangliosides

Maiko Miyata, Mariko Kambe, Orie Tajima, Setsuko Moriya, Hiromichi Sawaki, Hiroshi Hotta, Yuji Kondo, Hisashi Narimatsu, Taeko Miyagi, Koichi Furukawa, Keiko Furukawa

Cancer Sci. 2011 Dec; 102(12): 2139–2149. Published online 2011 Oct 17. doi: 10.1111/j.1349-7006.2011.02086.x

PMCID:: PMC11158141

Abstract Article PDF–1.0M

Select item 110415592.

EPO promotes the progression of rheumatoid arthritis by inducing desialylation via increasing the expression of neuraminidase 3

Gan Wu, Ben Cao, Haige Zhai, Bin Liu, Yuan Huang, Xiaowei Chen, Hanzhi Ling, Sunwang Ling, Shengwei Jin, Xinyu Yang, Jianguang Wang

Ann Rheum Dis. 2024 May; 83(5): 564–575. Published online 2024 Jan 25. doi: 10.1136/ard-2023-224852

PMCID:: PMC11041559

Abstract Article PDF–16M

Select item 97011523.

The extracellular sialidase NEU3 primes neutrophils

Sara A. Kirolos, Darrell Pilling, Richard H. Gomer

J Leukoc Biol. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: J Leukoc Biol. 2022 Dec; 112(6): 1399–1411. Published online 2022 Jul 28. doi: 10.1002/JLB.3A0422-217RR

Correction in:: J Leukoc Biol. 2024 Jan 11

PMCID:: PMC9701152

Abstract Article PDF–2.0M

Select item 85005454.

Reduced Sialylation and Bioactivity of the Antifibrotic Protein Serum Amyloid P in the Sera of Patients with Idiopathic Pulmonary Fibrosis

Wensheng Chen, Tejas R. Karhadkar, Changwan Ryu, Erica L. Herzog, Richard H. Gomer

Immunohorizons. Author manuscript; available in PMC 2021 Oct 8.

Published in final edited form as: Immunohorizons. 2020 Jun 23; 4(6): 352–362. Published online 2020 Jun 23. doi: 10.4049/immunohorizons.2000043

PMCID:: PMC8500545

Abstract Article PDF–1.2M

Select item 82827645.

N6-methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation

Yuanming Cheng, Wei Xie, Brian F Pickering, Karen L Chu, Angela M Savino, Xuejing Yang, Hanzhi Luo, Diu TT Nguyen, Shanlan Mo, Ersilia Barin, Anthony Velleca, Thomas Rohwetter, Dinshaw J Patel, Samie R Jaffrey, Michael G Kharas

Cancer Cell. Author manuscript; available in PMC 2022 Jul 12.

Published in final edited form as: Cancer Cell. 2021 Jul 12; 39(7): 958–972.e8. Published online 2021 May 27. doi: 10.1016/j.ccell.2021.04.017

PMCID:: PMC8282764

Abstract Article PDF–3.4M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76998647.

Role of NEU3 Overexpression in the Prediction of Efficacy of EGFR-Targeted Therapies in Colon Cancer Cell Lines

Federica Bovio, Samantha Epistolio, Alessandra Mozzi, Eugenio Monti, Paola Fusi, Matilde Forcella, Milo Frattini

Int J Mol Sci. 2020 Nov; 21(22): 8805. Published online 2020 Nov 20. doi: 10.3390/ijms21228805

PMCID:: PMC7699864

Abstract Article PDF–3.6M

Select item 71646588.

TGF-β1 Increases Sialidase 3 Expression in Human Lung Epithelial Cells by Decreasing its Degradation and Upregulating its Translation

Wensheng Chen, Teresa M. Lamb, Richard H. Gomer

Exp Lung Res. Author manuscript; available in PMC 2021 Apr 1.

Published in final edited form as: Exp Lung Res. 2020 Apr-May; 46(3-4): 75–80. Published online 2020 Feb 26. doi: 10.1080/01902148.2020.1733135

PMCID:: PMC7164658

Abstract Article PDF–704K

Select item 58269269.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 566348210.

Non-small cell lung cancer (NSCLC), EGFR downstream pathway activation and TKI targeted therapies sensitivity: Effect of the plasma membrane-associated NEU3

Matilde Forcella, Monica Oldani, Samantha Epistolio, Stefania Freguia, Eugenio Monti, Paola Fusi, Milo Frattini

PLoS One. 2017; 12(10): e0187289. Published online 2017 Oct 31. doi: 10.1371/journal.pone.0187289

PMCID:: PMC5663482

Abstract Article PDF–5.2M

Select item 553161111.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 548283512.

Human Sialidase Neu3 is S-Acylated and Behaves Like an Integral Membrane Protein

Macarena Rodriguez-Walker, Jose L. Daniotti

Sci Rep. 2017; 7: 4167. Published online 2017 Jun 23. doi: 10.1038/s41598-017-04488-w

PMCID:: PMC5482835

Abstract Article PDF–3.4M

Select item 486591013.

NEU3 Sialidase Protein Interactors in the Plasma Membrane and in the Endosomes

Federica Cirillo, Andrea Ghiroldi, Chiara Fania, Marco Piccoli, Enrica Torretta, Guido Tettamanti, Cecilia Gelfi, Luigi Anastasia

J Biol Chem. 2016 May 13; 291(20): 10615–10624. Published online 2016 Mar 17. doi: 10.1074/jbc.M116.719518

PMCID:: PMC4865910

Abstract Article PDF–2.0M

Select item 471467914.

Upregulation of sialidase NEU3 in head and neck squamous cell carcinoma associated with lymph node metastasis

Kiyoto Shiga, Kohta Takahashi, Ikuro Sato, Kengo Kato, Shigeru Saijo, Setsuko Moriya, Masahiro Hosono, Taeko Miyagi

Cancer Sci. 2015 Nov; 106(11): 1544–1553. Published online 2015 Oct 16. doi: 10.1111/cas.12810

PMCID:: PMC4714679

Abstract Article PDF–1.7M

Select item 461721115.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 440988116.

Increased sialidase activity in serum of cancer patients: Identification of sialidase and inhibitor activities in human serum

Keiko Hata, Tatsuo Tochigi, Ikuro Sato, Sadafumi Kawamura, Kazuhiro Shiozaki, Tadashi Wada, Kohta Takahashi, Setsuko Moriya, Kazunori Yamaguchi, Masahiro Hosono, Taeko Miyagi

Cancer Sci. 2015 Apr; 106(4): 383–389. Published online 2015 Mar 9. doi: 10.1111/cas.12627

PMCID:: PMC4409881

Abstract Article PDF–1.0M

Select item 437236417.

Potentiation of Epidermal Growth Factor-Mediated Oncogenic Transformation by Sialidase NEU3 Leading to Src Activation

Koji Yamamoto, Kohta Takahashi, Kazuhiro Shiozaki, Kazunori Yamaguchi, Setsuko Moriya, Masahiro Hosono, Hiroshi Shima, Taeko Miyagi

PLoS One. 2015; 10(3): e0120578. Published online 2015 Mar 24. doi: 10.1371/journal.pone.0120578

PMCID:: PMC4372364

Abstract Article PDF–4.0M

Select item 352228018.

The Plasma Membrane Sialidase NEU3 Regulates the Malignancy of Renal Carcinoma Cells by Controlling β1 Integrin Internalization and Recycling

Cristina Tringali, Barbara Lupo, Ilaria Silvestri, Nadia Papini, Luigi Anastasia, Guido Tettamanti, Bruno Venerando

J Biol Chem. 2012 Dec 14; 287(51): 42835–42845. Published online 2012 Nov 8. doi: 10.1074/jbc.M112.407718

PMCID:: PMC3522280

Abstract Article PDF–2.2M

Select item 348807719.

Sialidases on Mammalian Sperm Mediate Deciduous Sialylation during Capacitation

Fang Ma, Diana Wu, Liwen Deng, Patrick Secrest, June Zhao, Nissi Varki, Steven Lindheim, Pascal Gagneux

J Biol Chem. 2012 Nov 2; 287(45): 38073–38079. Published online 2012 Sep 18. doi: 10.1074/jbc.M112.380584

PMCID:: PMC3488077

Abstract Article PDF–1.4M

Select item 334611220.

NEU1 and NEU3 Sialidase Activity Expressed in Human Lung Microvascular Endothelia: NEU1 RESTRAINS ENDOTHELIAL CELL MIGRATION, WHEREAS NEU3 DOES NOT

Alan S. Cross, Sang Won Hyun, Alba Miranda-Ribera, Chiguang Feng, Anguo Liu, Chinh Nguyen, Lei Zhang, Irina G. Luzina, Sergei P. Atamas, William S. Twaddell, Wei Guang, Erik P. Lillehoj, Adam C. Puché, Wei Huang, Lai-Xi Wang, Antonino Passaniti, Simeon E. Goldblum

J Biol Chem. 2012 May 4; 287(19): 15966–15980. Published online 2012 Mar 8. doi: 10.1074/jbc.M112.346817

PMCID:: PMC3346112

Abstract Article PDF–2.8M

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