PMC Links for GEO Profiles (Select 8311145) - PMC

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Select item 99832951.

The nuclear receptor TLX (NR2E1) inhibits growth and progression of triple- negative breast cancer

Adam T. Nelczyk, Liqian Ma, Anasuya Das Gupta, Hashni Epa Vidana Gamage, Michael T. McHenry, Madeline A. Henn, Mohammed Kadiri, Yu Wang, Natalia Krawczynska, Shruti Bendre, Sisi He, Sayyed Hamed Shahoei, Zeynep Madak-Erdogan, Shih-Hsuan Hsiao, Tareq Saleh, Valerie Carpenter, David A. Gewirtz, Michael J. Spinella, Erik R. Nelson

Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2023 Aug 1.

Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2022 Nov 1; 1868(11): 166515. Published online 2022 Aug 4. doi: 10.1016/j.bbadis.2022.166515

PMCID:: PMC9983295

Abstract Article PDF–3.3M

Select item 98169252.

A NR2E1‐interacting peptide of LSD1 inhibits the proliferation of brain tumour initiating cells

Rong Hu, Umar Farook Shahul Hameed, Xiang Sun, Balakrishnan Shenbaga Moorthy, Wen Zhang, Philip D. Jeffrey, Li Zhou, Xin Ma, Fangjin Chen, Jianfeng Pei, Pankaj K. Giri, Yonggao Mou, Kunchithapadam Swaminathan, Ping Yuan

Cell Prolif. 2023 Jan; 56(1): e13350. Published online 2022 Nov 2. doi: 10.1111/cpr.13350

PMCID:: PMC9816925

Abstract Article PDF–4.3M

Select item 84623843.

TLX, an Orphan Nuclear Receptor With Emerging Roles in Physiology and Disease

Adam T Nelson, Yu Wang, Erik R Nelson

Endocrinology. 2021 Nov; 162(11): bqab184. Published online 2021 Aug 31. doi: 10.1210/endocr/bqab184

PMCID:: PMC8462384

Abstract Article

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80551205.

Orphan nuclear receptor TLX promotes immunosuppression via its transcriptional activation of PD-L1 in glioma

Jiayi Zhou, Xiaojuan Pei, Yingui Yang, Zhu Wang, Weijie Gao, Ran Ye, Xiantong Zhang, Jiangang Liu, Zhuohao Liu, Xinzhi Yang, Jingli Tao, Chunshan Gu, Wei Hu, Franky Lueng Chan, Xin Li, Jie Mao, Dinglan Wu

J Immunother Cancer. 2021; 9(4): e001937. Published online 2021 Apr 15. doi: 10.1136/jitc-2020-001937

PMCID:: PMC8055120

Abstract Article PDF–11M

Select item 80090486.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 79414587.

Tumorigenic effects of TLX overexpression in HEK 293T cells

Toshima Z. Parris, Dzeneta Vizlin‐Hodzic, Susanne Salmela, Keiko Funa

Cancer Rep (Hoboken) 2019 Oct; 2(5): e1204. Published online 2019 Jul 25. doi: 10.1002/cnr2.1204

PMCID:: PMC7941458

Abstract Article PDF–3.6M

Select item 67252878.

Pathological Aggression in “Fierce” Mice Corrected by Human Nuclear Receptor 2E1

Brett S. Abrahams, Melvin C. H. Kwok, Eric Trinh, Saeed Budaghzadeh, Sazzad M. Hossain, Elizabeth M. Simpson

J Neurosci. 2005 Jul 6; 25(27): 6263–6270. doi: 10.1523/JNEUROSCI.4757-04.2005

Correction in:: J Neurosci. 2005 Aug 3; 25(31): np.

PMCID:: PMC6725287

Abstract Article PDF–471K

Select item 66239129.

MicroRNA-9 Regulates Neurogenesis in Mouse Telencephalon by Targeting Multiple Transcription Factors

Mikihito Shibata, Hiromi Nakao, Hiroshi Kiyonari, Takaya Abe, Shinichi Aizawa

J Neurosci. 2011 Mar 2; 31(9): 3407–3422. doi: 10.1523/JNEUROSCI.5085-10.2011

PMCID:: PMC6623912

Abstract Article PDF–7.1M

Select item 607643910.

The tumor suppressor CIC directly regulates MAPK pathway genes via histone deacetylation

Simon Weissmann, Paul A. Cloos, Simone Sidoli, Ole N. Jensen, Steven Pollard, Kristian Helin

Cancer Res. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: Cancer Res. 2018 Aug 1; 78(15): 4114–4125. Published online 2018 May 29. doi: 10.1158/0008-5472.CAN-18-0342

PMCID:: PMC6076439

Abstract Article PDF–2.5M

Select item 553161111.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 542984712.

The role of the SWI/SNF chromatin remodeling complex in maintaining the stemness of glioma initiating cells

Hiroaki Hiramatsu, Kazuyoshi Kobayashi, Kyousuke Kobayashi, Takeshi Haraguchi, Yasushi Ino, Tomoki Todo, Hideo Iba

Sci Rep. 2017; 7: 889. Published online 2017 Apr 18. doi: 10.1038/s41598-017-00982-3

Correction in:: Sci Rep. 2018; 8: 16079.

PMCID:: PMC5429847

Abstract Article PDF–2.7M

Select item 479304313.

The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model

Kiyohito Murai, Guoqiang Sun, Peng Ye, E. Tian, Su Yang, Qi Cui, Guihua Sun, Daniel Trinh, Olivia Sun, Teresa Hong, Zhexing Wen, Markus Kalkum, Arthur D. Riggs, Hongjun Song, Guo-li Ming, Yanhong Shi

Nat Commun. 2016; 7: 10965. Published online 2016 Mar 11. doi: 10.1038/ncomms10965

PMCID:: PMC4793043

Abstract Article PDF–3.4M

Select item 474284314.

Downregulation of TLX induces TET3 expression and inhibits glioblastoma stem cell self-renewal and tumorigenesis

Qi Cui, Su Yang, Peng Ye, E. Tian, Guoqiang Sun, Jiehua Zhou, Guihua Sun, Xiaoxuan Liu, Chao Chen, Kiyohito Murai, Chunnian Zhao, Krist T. Azizian, Lu Yang, Charles Warden, Xiwei Wu, Massimo D'Apuzzo, Christine Brown, Behnam Badie, Ling Peng, Arthur D. Riggs, John J. Rossi, Yanhong Shi

Nat Commun. 2016; 7: 10637. Published online 2016 Feb 3. doi: 10.1038/ncomms10637

PMCID:: PMC4742843

Abstract Article PDF–3.5M

Select item 467329615.

Expression profiling of nuclear receptors in breast cancer identifies TLX as a mediator of growth and invasion in triple-negative breast cancer

Meng-Lay Lin, Hetal Patel, Judit Remenyi, Christopher R.S. Banerji, Chun-Fui Lai, Manikandan Periyasamy, Ylenia Lombardo, Claudia Busonero, Silvia Ottaviani, Alun Passey, Philip R. Quinlan, Colin A. Purdie, Lee B. Jordan, Alastair M. Thompson, Richard S. Finn, Oscar M. Rueda, Carlos Caldas, Jesus Gil, R. Charles Coombes, Frances V. Fuller-Pace, Andrew E. Teschendorff, Laki Buluwela, Simak Ali

Oncotarget. 2015 Aug 28; 6(25): 21685–21703. Published online 2015 May 13. doi: 10.18632/oncotarget.3942

PMCID:: PMC4673296

Abstract Article PDF–5.1M

Select item 461721116.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 446067317.

Integrative epigenomic and genomic filtering for methylation markers in hepatocellular carcinomas

Jing Shen, Clare LeFave, Iryna Sirosh, Abby B. Siegel, Benjamin Tycko, Regina M. Santella

BMC Med Genomics. 2015; 8: 28. Published online 2015 Jun 10. doi: 10.1186/s12920-015-0105-1

PMCID:: PMC4460673

Abstract Article PDF–1.1M

Select item 433529818.

Structural basis for corepressor assembly by the orphan nuclear receptor TLX

Xiaoyong Zhi, X. Edward Zhou, Yuanzheng He, Kelvin Searose-Xu, Chun-Li Zhang, Chih-Cheng Tsai, Karsten Melcher, H. Eric Xu

Genes Dev. 2015 Feb 15; 29(4): 440–450. doi: 10.1101/gad.254904.114

PMCID:: PMC4335298

Abstract Article PDF–1.5M

Select item 430533919.

The nuclear receptor NR2E1/TLX controls senescence

Ana O’Loghlen, Nadine Martin, Benjamin Krusche, Helen Pemberton, Marta M. Alonso, Hollie Chandler, Sharon Brookes, Simona Parrinello, Gordon Peters, Jesús Gil

Oncogene. Author manuscript; available in PMC 2016 Jan 30.

Published in final edited form as: Oncogene. 2015 Jul 30; 34(31): 4069–4077. Published online 2014 Oct 20. doi: 10.1038/onc.2014.335

PMCID:: PMC4305339

Abstract Article PDF–1.4M

Select item 423726620.

TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival

P L Chavali, R K R Saini, Q Zhai, D Vizlin-Hodzic, S Venkatabalasubramanian, A Hayashi, E Johansson, Z-j Zeng, S Mohlin, S Påhlman, L Hansford, D R Kaplan, K Funa

Cell Death Dis. 2014 Oct; 5(10): e1502. Published online 2014 Oct 30. doi: 10.1038/cddis.2014.449

PMCID:: PMC4237266

Abstract Article PDF–2.6M

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PMC Links for GEO Profiles (Select 8311145) (39)
PMC
Conserved Domain Links for Protein (Select 490533317) (1)
Conserved Domains
30S ribosomal protein S14 (chloroplast) [Dendrobium moniliforme]
30S ribosomal protein S14 (chloroplast) [Dendrobium moniliforme]
gi|2186797402|dbj|BBM29822.1|

Protein
Chain B, Unspecific peroxygenase
Chain B, Unspecific peroxygenase
gi|2833775648|pdb|8RNL|B

Protein
MAG: Bacteroides fragilis isolate CD10_MAG1, whole genome shotgun sequencing pro...
MAG: Bacteroides fragilis isolate CD10_MAG1, whole genome shotgun sequencing project
gi|2056638964|gb|JAGIQM000000000.1| M010000000

Nucleotide

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