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Select item 110949741.

Upregulated dual oxidase 1-induced oxidative stress and caspase-1-dependent pyroptosis reflect the etiologies of heart failure

Yan Song Li, Jingwen Xia, Chang Yuan Chen, Shu Hong Ren, Mao Rong He

BMC Mol Cell Biol. 2024; 25: 16. Published online 2024 May 15. doi: 10.1186/s12860-024-00506-8

PMCID:: PMC11094974

Abstract Article PDF–3.7M

Select item 99642172.

DUOX1 Gene Missense Mutation Confers Susceptibility on Type 2 Amiodarone-Induced Thyrotoxicosis

Olga Biakina, Yulia Mitina, Daria Gognieva, Marina Axenova, Alexandra Ermolaeva, Afina Bestavashvili, Valentin Fadeev, Abram Syrkin, Philipp Kopylov

Int J Mol Sci. 2023 Feb; 24(4): 4016. Published online 2023 Feb 16. doi: 10.3390/ijms24044016

PMCID:: PMC9964217

Abstract Article PDF–250K

Select item 99429053.

Diet-induced obesity worsens allergen-induced type 2/type 17 inflammation in airways by enhancing DUOX1 activation

Aida Habibovic, Milena Hristova, Carolyn R. Morris, Miao-Chong Joy Lin, Litiele C. Cruz, Jennifer L. Ather, Miklós Geiszt, Vikas Anathy, Yvonne M. W. Janssen-Heininger, Matthew E. Poynter, Anne E. Dixon, Albert van der Vliet

Am J Physiol Lung Cell Mol Physiol. 2023 Feb 1; 324(2): L228–L242. Published online 2023 Jan 10. doi: 10.1152/ajplung.00331.2022

PMCID:: PMC9942905

Abstract Article

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79348425.

Downregulation of epithelial DUOX1 in chronic obstructive pulmonary disease

Caspar Schiffers, Cheryl van de Wetering, Robert A. Bauer, Aida Habibovic, Milena Hristova, Christopher M. Dustin, Sara Lambrichts, Pamela M. Vacek, Emiel F.M. Wouters, Niki L. Reynaert, Albert van der Vliet

JCI Insight. 2021 Jan 25; 6(2): e142189. Published online 2021 Jan 25. doi: 10.1172/jci.insight.142189

PMCID:: PMC7934842

Abstract Article PDF–2.9M

Select item 78834046.

Knockdown of Dual Oxidase 1 (DUOX1) Promotes Wound Healing by Regulating Reactive Oxygen Species (ROS) by Activation of Nuclear Factor kappa B (NF-κB) Signaling

Hui Wang, Haowei Lu, Yige Wu

Med Sci Monit. 2021; 27: e926492-1–e926492-11. Prepublished online 2020 Dec 8. Published online 2021 Feb 10. doi: 10.12659/MSM.926492

PMCID:: PMC7883404

Abstract Article PDF–1.5M

Select item 77943437.

Structures of human dual oxidase 1 complex in low-calcium and high-calcium states

Jing-Xiang Wu, Rui Liu, Kangcheng Song, Lei Chen

Nat Commun. 2021; 12: 155. Published online 2021 Jan 8. doi: 10.1038/s41467-020-20466-9

PMCID:: PMC7794343

Abstract Article PDF–2.7M

Select item 75237068.

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis

Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D. Malihi, Mincheol Park, Ruth M. Alvarez, Li Peng Yap, Parag Mallick, Jonathan E. Katz, Mitchell E. Gross, Kian Kani

Oncogene. Author manuscript; available in PMC 2020 Sep 29.

Published in final edited form as: Oncogene. 2019 Apr; 38(16): 3003–3018. Published online 2018 Dec 21. doi: 10.1038/s41388-018-0638-9

PMCID:: PMC7523706

Abstract Article PDF–2.3M

Select item 73220679.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 684248510.

Dual oxidase 1 and NADPH oxidase 2 exert favorable effects in cervical cancer patients by activating immune response

Sang Yeon Cho, Sungha Kim, Mi-Ju Son, Gwanghun Kim, Parul Singh, Ha Neul Kim, Hei-Gwon Choi, Heon Jong Yoo, Young Bok Ko, Byung Seok Lee, Hyuk Soo Eun

BMC Cancer. 2019; 19: 1078. Published online 2019 Nov 9. doi: 10.1186/s12885-019-6202-3

PMCID:: PMC6842485

Abstract Article PDF–4.1M

Select item 638976511.

Congenital Hypothyroidism due to Oligogenic Mutations in Two Sudanese Families

Yui Watanabe, Ryan J. Bruellman, Reham S. Ebrhim, Mohamed A. Abdullah, Alexandra M. Dumitrescu, Samuel Refetoff, Roy E. Weiss

Thyroid. 2019 Feb 1; 29(2): 302–304. Published online 2019 Feb 11. doi: 10.1089/thy.2018.0295

PMCID:: PMC6389765

Abstract Article PDF–176K

Select item 616668212.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 593301113.

DUOX1 Silencing in Mammary Cell Alters the Response to Genotoxic Stress

Rodrigo S. Fortunato, Luciana R. Gomes, Veridiana Munford, Carolina Fittipaldi Pessoa, Annabel Quinet, Fabio Hecht, Gustavo S. Kajitani, Cristiane Bedran Milito, Denise P. Carvalho, Carlos Frederico Martins Menck

Oxid Med Cell Longev. 2018; 2018: 3570526. Published online 2018 Apr 19. doi: 10.1155/2018/3570526

PMCID:: PMC5933011

Abstract Article PDF–2.0M

Select item 590099414.

Dual oxidase: a novel therapeutic target in allergic disease

Albert van der Vliet, Karamatullah Danyal, David E Heppner

Br J Pharmacol. 2018 May; 175(9): 1401–1418. Published online 2018 Mar 15. doi: 10.1111/bph.14158

PMCID:: PMC5900994

Abstract Article PDF–1.4M

Select item 563534715.

Autophagy regulates DUOX1 localization and superoxide production in airway epithelial cells during chronic IL-13 stimulation

John D. Dickinson, Jenea M. Sweeter, Kristi J. Warren, Iman M. Ahmad, Xavier De Deken, Matthew C. Zimmerman, Steven L. Brody

Redox Biol. 2018 Apr; 14: 272–284. Published online 2017 Sep 22. doi: 10.1016/j.redox.2017.09.013

PMCID:: PMC5635347

Abstract Article PDF–2.0M

Select item 558707916.

Digenic DUOX1 and DUOX2 Mutations in Cases With Congenital Hypothyroidism

Zehra Aycan, Hakan Cangul, Marina Muzza, Veysel N. Bas, Laura Fugazzola, V. Krishna Chatterjee, Luca Persani, Nadia Schoenmakers

J Clin Endocrinol Metab. 2017 Sep 1; 102(9): 3085–3090. Published online 2017 Jun 16. doi: 10.1210/jc.2017-00529

PMCID:: PMC5587079

Abstract Article

Select item 491015017.

F-box only protein 9 is an E3 ubiquitin ligase of PPARγ

Kyeong Won Lee, Soo Heon Kwak, Young Do Koo, Yun-Kyung Cho, Hak Mo Lee, Hye Seung Jung, Young Min Cho, Young Joo Park, Sung Soo Chung, Kyong Soo Park

Exp Mol Med. 2016 May; 48(5): e234. Published online 2016 May 20. doi: 10.1038/emm.2016.31

PMCID:: PMC4910150

Abstract Article PDF–1.1M

Select item 486993818.

Dual oxidase 1: A predictive tool for the prognosis of hepatocellular carcinoma patients

SHENGSEN CHEN, QINGXIA LING, KANGKANG YU, CHONG HUANG, NING LI, JIANMING ZHENG, SUXIA BAO, QI CHENG, MENGQI ZHU, MINGQUAN CHEN

Oncol Rep. 2016 Jun; 35(6): 3198–3208. Published online 2016 Apr 14. doi: 10.3892/or.2016.4745

PMCID:: PMC4869938

Abstract Article PDF–1000K

Select item 486002419.

Airway epithelial DUOX1 mediates allergen-induced IL-33 secretion and activation of type 2 immune responses

Milena Hristova, Aida Habibovic, Carmen Veith, Yvonne M.W. Janssen-Heininger, Anne E. Dixon, Miklos Geiszt, Albert van der Vliet

J Allergy Clin Immunol. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: J Allergy Clin Immunol. 2016 May; 137(5): 1545–1556.e11. Published online 2015 Nov 17. doi: 10.1016/j.jaci.2015.10.003

PMCID:: PMC4860024

Abstract Article PDF–2.4M

Select item 484413520.

Nox4 and Duox1/2 Mediate Redox Activation of Mesenchymal Cell Migration by PDGF

Pyotr A. Tyurin-Kuzmin, Nadezhda D. Zhdanovskaya, Anna A. Sukhova, George D. Sagaradze, Eugene A. Albert, Ludmila V. Ageeva, George V. Sharonov, Alexander V. Vorotnikov, Vsevolod A. Tkachuk

PLoS One. 2016; 11(4): e0154157. Published online 2016 Apr 25. doi: 10.1371/journal.pone.0154157

PMCID:: PMC4844135

Abstract Article PDF–4.5M

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PMC Links for GEO Profiles (Select 83269982) (44)
PMC
Mus musculus zinc finger protein 827 (Zfp827), transcript variant 1, mRNA
Mus musculus zinc finger protein 827 (Zfp827), transcript variant 1, mRNA
gi|2186289434|ref|NM_178267.4|

Nucleotide
Mus musculus sorting nexin 10 (Snx10), transcript variant 10, mRNA
Mus musculus sorting nexin 10 (Snx10), transcript variant 10, mRNA
gi|1371977066|ref|NM_001361582.1|

Nucleotide
ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit, partial (chloropl...
ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit, partial (chloroplast) [Medicago sativa]
gi|2805779543|gb|XGZ25661.1|

Protein
PREDICTED: Homo sapiens Ras association domain family member 3 (RASSF3), transcr...
PREDICTED: Homo sapiens Ras association domain family member 3 (RASSF3), transcript variant X1, mRNA
gi|2217288609|ref|XM_047428711.1|

Nucleotide

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