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Select item 102374221.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 94253122.

Specific inhibition of the transporter MRP4/ABCC4 affects multiple signaling pathways and thrombus formation in human platelets

Robert Wolf, Sophie Grammbauer, Raghavendra Palankar, Céline Tolksdorf, Eileen Moritz, Andreas Böhm, Mahmoud Hasan, Annika Hafkemeyer, Andreas Greinacher, Mladen V. Tzvetkov, Bernhard H. Rauch, Gabriele Jedlitschky

Haematologica. 2022 Sep 1; 107(9): 2206–2217. Published online 2022 Mar 17. doi: 10.3324/haematol.2021.279761

PMCID:: PMC9425312

Abstract Article PDF–1.9M

Select item 92316233.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 90375544.

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy

Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell

Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116

PMCID:: PMC9037554

Abstract Article PDF–4.1M

Select item 89515565.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 89099726.

The Daily Expression of ABCC4 at the BCSFB Affects the Transport of Its Substrate Methotrexate

André Furtado, Rafael Mineiro, Ana Catarina Duarte, Isabel Gonçalves, Cecília R. Santos, Telma Quintela

Int J Mol Sci. 2022 Mar; 23(5): 2443. Published online 2022 Feb 23. doi: 10.3390/ijms23052443

PMCID:: PMC8909972

Abstract Article PDF–1.9M

Select item 88011377.

Founder genetic variants of ABCC4 and ABCC11 in the Japanese population are not associated with the development of subacute myelo‐optico‐neuropathy (SMON)

Hideki Matsumoto, Hideo Sasai, Norio Kawamoto, Masato Katsuyama, Makoto Minamiyama, Satoshi Kuru, Toshiyuki Fukao, Hidenori Ohnishi, SMON research group members

Mol Genet Genomic Med. 2022 Jan; 10(1): e1845. Published online 2021 Dec 24. doi: 10.1002/mgg3.1845

PMCID:: PMC8801137

Abstract Article PDF–396K

Select item 83720928.

Polymorphisms in the CYP2A6 and ABCC4 genes are associated with a protective effect on chronic myeloid leukemia in the Brazilian Amazon population

Natasha Monte, Karla B. C. C. Pantoja, Juliana C. G. Rodrigues, Darlen C. de Carvalho, Tereza C. B. Azevedo, Esdras E. B. Pereira, Paulo P. de Assumpção, Sidney E. B. dos Santos, Marianne R. Fernandes, Ney P. C. dos Santos

Mol Genet Genomic Med. 2021 Jul; 9(7): e1694. Published online 2021 May 29. doi: 10.1002/mgg3.1694

PMCID:: PMC8372092

Abstract Article PDF–450K

Select item 83145479.

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation

Ruona Shi, Xue Shi, Dajiang Qin, Shibing Tang, Michiel Vermeulen, Xiaofei Zhang

Cell Biosci. 2021; 11: 146. Published online 2021 Jul 27. doi: 10.1186/s13578-021-00659-5

PMCID:: PMC8314547

Abstract Article PDF–3.7M

Select item 823888210.

Novel risk factors for glucarpidase use in pediatric acute lymphoblastic leukemia: Hispanic ethnicity, age, and the ABCC4 gene

Mark Zobeck, M. Brooke Bernhardt, Kala Y. Kamdar, Karen R. Rabin, Philip J. Lupo, Michael E. Scheurer

Pediatr Blood Cancer. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Pediatr Blood Cancer. 2021 Aug; 68(8): e29036. Published online 2021 Mar 31. doi: 10.1002/pbc.29036

PMCID:: PMC8238882

Abstract Article PDF–677K

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 764415512.

Circular RNA circABCC4 acts as a ceRNA of miR-154-5p to improve cell viability, migration and invasion of breast cancer cells in vitro

Jianchun Jiang, Xunquan Cheng

Cell Cycle. 2020; 19(20): 2653–2661. Published online 2020 Oct 6. doi: 10.1080/15384101.2020.1815147

PMCID:: PMC7644155

Abstract Article PDF–1.3M

Select item 758912613.

Roles of ABCC1 and ABCC4 in Proliferation and Migration of Breast Cancer Cell Lines

Floren G. Low, Kiran Shabir, James E. Brown, Roslyn M. Bill, Alice J. Rothnie

Int J Mol Sci. 2020 Oct; 21(20): 7664. Published online 2020 Oct 16. doi: 10.3390/ijms21207664

PMCID:: PMC7589126

Abstract Article PDF–3.6M

Select item 745004514.

Multidrug transporter MRP4/ABCC4 as a key determinant of pancreatic cancer aggressiveness

A. Sahores, A. Carozzo, M. May, N. Gómez, N. Di Siervi, M. De Sousa Serro, A. Yaneff, A. Rodríguez-González, M. Abba, C. Shayo, C. Davio

Sci Rep. 2020; 10: 14217. Published online 2020 Aug 26. doi: 10.1038/s41598-020-71181-w

PMCID:: PMC7450045

Abstract Article PDF–8.1M

Select item 741669715.

An ABC transporter drives the Sonic Hedgehog pathway contributing to medulloblastoma pathogenesis

Juwina Wijaya, BaoHan T Vo, Jingjing Liu, Beisi Xu, Gang Wu, Yao Wang, Junmin Peng, Jin Zhang, Laura J Janke, Brent A Orr, Jiyang Yu, Martine F Roussel, John D Schuetz

Cancer Res. Author manuscript; available in PMC 2020 Aug 10.

Published in final edited form as: Cancer Res. 2020 Apr 1; 80(7): 1524–1537. Published online 2020 Jan 16. doi: 10.1158/0008-5472.CAN-19-2054

PMCID:: PMC7416697

Abstract Article PDF–3.4M

Select item 700536216.

Lack of the multidrug transporter MRP4/ABCC4 defines the PEL-negative blood group and impairs platelet aggregation

Slim Azouzi, Mahmoud Mikdar, Patricia Hermand, Emilie-Fleur Gautier, Virginie Salnot, Alexandra Willemetz, Gaël Nicolas, Cédric Vrignaud, Alexandre Raneri, Patrick Mayeux, Christine Bole‐Feysot, Patrick Nitschké, Jean-Pierre Cartron, Yves Colin, Olivier Hermine, Gabriele Jedlitschky, Marc Cloutier, Jessica Constanzo-Yanez, Carole Ethier, Nancy Robitaille, Maryse St-Louis, Caroline Le Van Kim, Thierry Peyrard

Blood. 2020 Feb 6; 135(6): 441–448. Prepublished online 2019 Dec 11. doi: 10.1182/blood.2019002320

PMCID:: PMC7005362

Abstract Article

Select item 691880917.

Multidrug resistance-associated protein 4 is a determinant of arsenite resistance

Bo Yuan, Yuta Yoshino, Hisayo Fukushima, Svetlana Markova, Norio Takagi, Hiroo Toyoda, Deanna L. Kroetz

Oncol Rep. 2016 Jan; 35(1): 147–154. Published online 2015 Oct 22. doi: 10.3892/or.2015.4343

PMCID:: PMC6918809

Abstract Article PDF–792K

Select item 681313818.

TNFα Induces Multidrug Resistance-Associated Protein 4 Expression through p38-E2F1-Nrf2 Signaling in Obstructive Cholestasis

Wei Lian, Xiaocong Liu, Wensheng Chen

Yonsei Med J. 2019 Nov 1; 60(11): 1045–1053. Published online 2019 Oct 17. doi: 10.3349/ymj.2019.60.11.1045

PMCID:: PMC6813138

Abstract Article PDF–575K

Select item 675444619.

Regulation of the endosomal SNX27-retromer by OTULIN

Aurelia Stangl, Paul R. Elliott, Adan Pinto-Fernandez, Sarah Bonham, Luke Harrison, Annalisa Schaub, Kerstin Kutzner, Kirstin Keusekotten, Paul T. Pfluger, Farid El Oualid, Benedikt M. Kessler, David Komander, Daniel Krappmann

Nat Commun. 2019; 10: 4320. Published online 2019 Sep 20. doi: 10.1038/s41467-019-12309-z

PMCID:: PMC6754446

Abstract Article PDF–6.0M

Select item 669137420.

MRP4 sustains Wnt/β-catenin signaling for pregnancy, endometriosis and endometrial cancer

Jun-Jiang Chen, Zhi-Jie Xiao, Xiaojing Meng, Yan Wang, Mei Kuen Yu, Wen Qing Huang, Xiao Sun, Hao Chen, Yong-Gang Duan, Xiaohua Jiang, Maria Pik Wong, Hsiao Chang Chan, Fei Zou, Ye Chun Ruan

Theranostics. 2019; 9(17): 5049–5064. Published online 2019 Jul 9. doi: 10.7150/thno.32097

PMCID:: PMC6691374

Abstract Article PDF–3.6M

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