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Select item 111721881.

Distinct Effects of Respiratory Viral Infection Models on miR-149-5p, IL-6 and p63 Expression in BEAS-2B and A549 Epithelial Cells

Nafeesa Shahdab, Christopher Ward, Philip M. Hansbro, Stephen Cummings, John S. Young, Fatemeh Moheimani

Cells. 2024 Jun; 13(11): 919. Published online 2024 May 26. doi: 10.3390/cells13110919

PMCID:: PMC11172188

Abstract Article PDF–4.3M

Select item 111598822.

Overexpression of ΔNp63α induces a stem cell phenotype in MCF7 breast carcinoma cell line through the Notch pathway

Zhijian Du, Jing Li, Liang Wang, Chunjing Bian, Qingliang Wang, Lianming Liao, Xiaowei Dou, Xiuwu Bian, Robert Chunhua Zhao

Cancer Sci. 2010 Nov; 101(11): 2417–2424. Published online 2010 Aug 2. doi: 10.1111/j.1349-7006.2010.01700.x

PMCID:: PMC11159882

Abstract Article PDF–1.0M

Select item 111053243.

A double dealing tale of p63: an oncogene or a tumor suppressor

Yonglong Chen, Yougong Peng, Shijie Fan, Yimin Li, Zhi-Xiong Xiao, Chenghua Li

Cell Mol Life Sci. 2018 Mar; 75(6): 965–973. Published online 2017 Oct 3. doi: 10.1007/s00018-017-2666-y

PMCID:: PMC11105324

Abstract Article PDF–660K

Select item 109622064.

TP63 truncating mutation causes increased cell apoptosis and premature ovarian insufficiency by enhanced transcriptional activation of CLCA2

Yali Fan, Shuya Chen, Chunfang Chu, Xiaodan Yin, Jing Jin, Lingyan Zhang, Huihui Yan, Zheng Cao, Ruixia Liu, Mingwei Xin, Lin Li, Chenghong Yin

J Ovarian Res. 2024; 17: 67. Published online 2024 Mar 25. doi: 10.1186/s13048-024-01396-2

Correction in:: J Ovarian Res. 2024; 17: 93.

PMCID:: PMC10962206

Abstract Article PDF–4.0M

Select item 109547595.

Reciprocal inhibition between TP63 and STAT1 regulates anti-tumor immune response through interferon-γ signaling in squamous cancer

Yuan Jiang, Yueyuan Zheng, Yuan-Wei Zhang, Shuai Kong, Jinxiu Dong, Fei Wang, Benjamin Ziman, Sigal Gery, Jia-Jie Hao, Dan Zhou, Jianian Zhou, Allen S. Ho, Uttam K. Sinha, Jian Chen, Shuo Zhang, Chuntong Yin, Dan-Dan Wei, Masaharu Hazawa, Huaguang Pan, Zhihao Lu, Wen-Qiang Wei, Ming-Rong Wang, H. Phillip Koeffler, De-Chen Lin, Yan-Yi Jiang

Nat Commun. 2024; 15: 2484. Published online 2024 Mar 20. doi: 10.1038/s41467-024-46785-9

PMCID:: PMC10954759

Abstract Article PDF–8.0M

Select item 106710906.

Association between IRF6, TP63, GREM1 Gene Polymorphisms and Non-Syndromic Orofacial Cleft Phenotypes in Vietnamese Population: A Case–Control and Family-Based Study

Loc Nguyen Gia Pham, Teruyuki Niimi, Satoshi Suzuki, Minh Duc Nguyen, Linh Cao Hoai Nguyen, Tuan Duc Nguyen, Kien Ai Hoang, Duc Minh Nguyen, Chisato Sakuma, Toko Hayakawa, Makino Hiyori, Nagana Natsume, Hiroo Furukawa, Hideto Imura, Junko Akashi, Tohru Ohta, Nagato Natsume

Genes (Basel) 2023 Nov; 14(11): 1995. Published online 2023 Oct 25. doi: 10.3390/genes14111995

PMCID:: PMC10671090

Abstract Article PDF–1.6M

Select item 106380927.

p63: a crucial player in epithelial stemness regulation

Yanan Li, Sara Giovannini, Tingting Wang, Jiankai Fang, Peishan Li, Changshun Shao, Ying Wang, TOR centre, Yufang Shi, Eleonora Candi, Gerry Melino, Francesca Bernassola

Oncogene. 2023; 42(46): 3371–3384. Published online 2023 Oct 17. doi: 10.1038/s41388-023-02859-4

PMCID:: PMC10638092

Abstract Article PDF–4.0M

Select item 104220688.

A novel de novo TP63 mutation in whole‐exome sequencing of a Syrian family with Oral cleft and ectrodactyly

Claire L. Simpson, Danielle C. Kimble, Settara C. Chandrasekharappa, NISC Comparative Sequencing Program, Khalid Alqosayer, Emily Holzinger, Blake Carrington, John McElderry, Raman Sood, Ghiath Al‐Souqi, Hasan Albacha‐Hejazi, Joan E. Bailey‐Wilson

Mol Genet Genomic Med. 2023 Aug; 11(8): e2179. Published online 2023 Apr 18. doi: 10.1002/mgg3.2179

PMCID:: PMC10422068

Abstract Article PDF–6.2M

Select item 101658259.

Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression

Boting Ning, Andrew M. Tilston-Lunel, Justice Simonetti, Julia Hicks-Berthet, Adeline Matschulat, Roxana Pfefferkorn, Avrum Spira, Matthew Edwards, Sarah Mazzilli, Marc E. Lenburg, Jennifer E. Beane, Xaralabos Varelas

J Exp Clin Cancer Res. 2023; 42: 116. Published online 2023 May 8. doi: 10.1186/s13046-023-02674-5

PMCID:: PMC10165825

Abstract Article PDF–4.0M

Select item 1011324610.

Christian Osterburg, Marco Ferniani, Dario Antonini, Ann-Sophie Frombach, Ludovica D’Auria, Susanne Osterburg, Rebecca Lotz, Frank Löhr, Sebastian Kehrloesser, Huiqing Zhou, Caterina Missero, Volker Dötsch

Cell Death Dis. 2023 Apr; 14(4): 274. Published online 2023 Apr 18. doi: 10.1038/s41419-023-05796-y

PMCID:: PMC10113246

Abstract Article PDF–5.8M

Select item 1003550811.

The Splicing Factor PTBP1 Represses TP63 γ Isoform Production in Squamous Cell Carcinoma

William Taylor, Stéphane Deschamps, David Reboutier, Luc Paillard, Agnès Méreau, Yann Audic

Cancer Res Commun. 2022 Dec; 2(12): 1669–1683. Published online 2022 Dec 20. doi: 10.1158/2767-9764.CRC-22-0350

PMCID:: PMC10035508

Abstract Article PDF–8.5M

Select item 997409512.

TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis

Chengzi Huang, Simin Zhao, Yajuan Yang, Ting Guo, Hanni Ke, Xin Mi, Yingying Qin, Zi-Jiang Chen, Shidou Zhao

J Clin Invest. 2023 Mar 1; 133(5): e162315. Published online 2023 Mar 1. doi: 10.1172/JCI162315

PMCID:: PMC9974095

Abstract Article PDF–3.1M

Select item 966421513.

The analysis of the pyroptosis-related genes and hub gene TP63 ceRNA axis in osteosarcoma

Jun Han, Yunxiang Hu, Shengqiang Ding, Sanmao Liu, Hong Wang

Front Immunol. 2022; 13: 974916. Published online 2022 Nov 1. doi: 10.3389/fimmu.2022.974916

PMCID:: PMC9664215

Abstract Article PDF–9.0M

Select item 960358214.

Possible Involvement of the Upregulation of ΔNp63 Expression Mediated by HER2-Activated Aryl Hydrocarbon Receptor in Mammosphere Maintenance

Yuichiro Kanno, Nao Saito, Naoya Yamashita, Kazuki Ota, Ryota Shizu, Takuomi Hosaka, Kiyomitsu Nemoto, Kouichi Yoshinari

Int J Mol Sci. 2022 Oct; 23(20): 12095. Published online 2022 Oct 11. doi: 10.3390/ijms232012095

PMCID:: PMC9603582

Abstract Article PDF–1.3M

Select item 954206215.

Dominant TP63 missense variants lead to constitutive activation and premature ovarian insufficiency

Elena J. Tucker, Niklas Gutfreund, Marc‐Antoine Belaud‐Rotureau, David Gilot, Tiffany Brun, Brianna L. Kline, Katrina M. Bell, Mathilde Domin‐Bernhard, Camille Théard, Philippe Touraine, Gorjana Robevska, Jocelyn van van den Bergen, Katie L. Ayers, Andrew H. Sinclair, Volker Dötsch, Sylvie Jaillard

Hum Mutat. 2022 Oct; 43(10): 1443–1453. Published online 2022 Jul 29. doi: 10.1002/humu.24432

PMCID:: PMC9542062

Abstract Article PDF–2.1M

Select item 950910716.

Inactivation of tumor suppressor TAp63 by hepatitis B virus X protein in hepatocellular carcinoma

Bangxiang Xie, Qian Hao, Xiang Zhou, Dexi Chen

Chin Med J (Engl) 2022 Jul 20; 135(14): 1728–1733. Published online 2022 Aug 10. doi: 10.1097/CM9.0000000000002283

PMCID:: PMC9509107

Abstract Article PDF–3.4M

Select item 928100617.

Identification of a novel heterozygous missense TP63 variant in a Chinese pedigree with split-hand/foot malformation

Mingzhu Miao, Shoulian Lu, Xiao Sun, Meng Zhao, Jue Wang, Xiaotan Su, Bai Jin, Lizhou Sun

BMC Med Genomics. 2022; 15: 157. Published online 2022 Jul 13. doi: 10.1186/s12920-022-01311-y

PMCID:: PMC9281006

Abstract Article PDF–1.6M

Select item 926681818.

CDK1 Promotes Epithelial–Mesenchymal Transition and Migration of Head and Neck Squamous Carcinoma Cells by Repressing ∆Np63α-Mediated Transcriptional Regulation

Huimin Chen, Ke Hu, Ying Xie, Yucheng Qi, Wenjuan Li, Yaohui He, Shijie Fan, Wen Liu, Chenghua Li

Int J Mol Sci. 2022 Jul; 23(13): 7385. Published online 2022 Jul 2. doi: 10.3390/ijms23137385

PMCID:: PMC9266818

Abstract Article PDF–3.0M

Select item 925966719.

p63 silencing induces epigenetic modulation to enhance human cardiac fibroblast to cardiomyocyte-like differentiation

Jaya Pratap Pinnamaneni, Vivek P. Singh, Mary B. Kim, Christopher T. Ryan, Aarthi Pugazenthi, Deepthi Sanagasetti, Megumi Mathison, Jianchang Yang, Todd K. Rosengart

Sci Rep. 2022; 12: 11416. Published online 2022 Jul 6. doi: 10.1038/s41598-022-15559-y

PMCID:: PMC9259667

Abstract Article PDF–3.2M

Select item 904394620.

The TΑp63/BCL2 axis represents a novel mechanism of clinical aggressiveness in chronic lymphocytic leukemia

Stamatia Laidou, Dionysios Grigoriadis, Sofia Papanikolaou, Spyros Foutadakis, Stavroula Ntoufa, Maria Tsagiopoulou, Giannis Vatsellas, Achilles Anagnostopoulos, Anastasia Kouvatsi, Niki Stavroyianni, Fotis Psomopoulos, Antonios M. Makris, Marios Agelopoulos, Dimitris Thanos, Anastasia Chatzidimitriou, Nikos Papakonstantinou, Kostas Stamatopoulos

Blood Adv. 2022 Apr 26; 6(8): 2646–2656. Published online 2022 Apr 22. doi: 10.1182/bloodadvances.2021006348

PMCID:: PMC9043946

Abstract Article PDF–1.5M

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