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Items: 1 to 20 of 50

1.
Mylip makes an Idol turn into regulation of LDL receptor
Dan Lindholm, Beat C. Bornhauser, Laura Korhonen
Cell Mol Life Sci. 2009 Nov; 66(21): 3399–3402. Published online 2009 Aug 18. doi: 10.1007/s00018-009-0127-y
PMCID:
PMC11115883
AbstractArticlePDF–116K
2.
Common Genetic Variation and Antidepressant Efficacy in Major Depressive Disorder: A Meta-Analysis of Three Genome-Wide Pharmacogenetic Studies
GENDEP Investigators, Rudolf Uher, Katherine E. Tansey, Marcella Rietschel, Neven Henigsberg, Wolfgang Maier, Ole Mors, Joanna Hauser, Anna Placentino, Daniel Souery, Anne Farmer, Katherine J. Aitchison, Ian Craig, Peter McGuffin, Cathryn M. Lewis, MARS Investigators, Marcus Ising, Susanne Lucae, Elisabeth B. Binder, Stefan Kloiber, Florian Holsboer, Bertram Müller-Myhsok, STAR*D Investigators, Stephan Ripke, Steven P. Hamilton, Jared Soundy, Gonzalo Laje, Francis J. McMahon, Maurizio Fava, A. John Rush, Roy H. Perlis
Am J Psychiatry. Author manuscript; available in PMC 2023 Aug 11.
Published in final edited form as: Am J Psychiatry. 2013 Feb; 170(2): 207–217. doi: 10.1176/appi.ajp.2012.12020237
PMCID:
PMC10416089
AbstractArticlePDF–1.4M
3.
Effect of type 2 diabetes on the inducible degrader of LDL receptor
Sum Lam, David Tak Wai Lui, Sammy Wing Ming Shiu, Ying Wong, Kathryn Choon Beng Tan
J Lipid Res. 2023 Jun; 64(6): 100380. Published online 2023 Apr 23. doi: 10.1016/j.jlr.2023.100380
PMCID:
PMC10230263
AbstractArticlePDF–1.3M
4.
Mouse Spinal Cord Vascular Transcriptome Analysis Identifies CD9 and MYLIP as Injury-Induced Players
Isaura Martins, Dalila Neves-Silva, Mariana Ascensão-Ferreira, Ana Filipa Dias, Daniel Ribeiro, Ana Filipa Isidro, Raquel Quitéria, Diogo Paramos-de-Carvalho, Nuno L. Barbosa-Morais, Leonor Saúde
Int J Mol Sci. 2023 Apr; 24(7): 6433. Published online 2023 Mar 29. doi: 10.3390/ijms24076433
PMCID:
PMC10094762
AbstractArticlePDF–8.0M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
Genetic polymorphism of IDOL gene was associated with the susceptibility of coronary artery disease in Han population in Xinjiang, China
Dilare Adi, Jialin Abuzhalihan, Jing Tao, Yun Wu, Ying-Hong Wang, Fen Liu, Yi-Ning Yang, Xiang Ma, Xiao-Mei Li, Xiang Xie, Zhen-Yan Fu, Yi-Tong Ma
Hereditas. 2021; 158: 12. Published online 2021 Apr 12. doi: 10.1186/s41065-021-00178-w
Correction in:
Hereditas. 2021; 158: 19.
PMCID:
PMC8042894
AbstractArticlePDF–760K
7.
SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1
Ju-Qiong Wang, Zi-Cun Lin, Liang-Liang Li, Shao-Fang Zhang, Wei-Hui Li, Wei Liu, Bao-Liang Song, Jie Luo
J Biol Chem. 2021 Jan-Jun; 296: 100032. Published online 2020 Nov 23. doi: 10.1074/jbc.RA120.015420
PMCID:
PMC7948399
AbstractArticlePDF–2.8M
8.
Receptor‐mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy
Amelia E Ohnstad, Jose M Delgado, Brian J North, Isha Nasa, Arminja N Kettenbach, Sebastian W Schultz, Christopher J Shoemaker
EMBO J. 2020 Dec 15; 39(24): e104948. Published online 2020 Nov 23. doi: 10.15252/embj.2020104948
PMCID:
PMC7737610
AbstractArticlePDF–3.7M
9.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
10.
Structural analysis of the LDL receptor–interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site
Luca Martinelli, Athanassios Adamopoulos, Patrik Johansson, Paul T. Wan, Jenny Gunnarsson, Hongwei Guo, Helen Boyd, Noam Zelcer, Titia K. Sixma
J Biol Chem. 2020 Sep 25; 295(39): 13570–13583. Published online 2020 Jul 29. doi: 10.1074/jbc.RA120.014349
PMCID:
PMC7521653
AbstractArticlePDF–2.9M
11.
IDOL gene variant is associated with hyperlipidemia in Han population in Xinjiang, China
Dilare Adi, Jialin Abuzhalihan, Ying-hong Wang, Gulinaer Baituola, Yun Wu, Xiang Xie, Zhen-Yan Fu, Yi-Ning Yang, Xiang Ma, Xiao-Mei Li, Bang-dang Chen, Fen Liu, Yi-Tong Ma
Sci Rep. 2020; 10: 14280. Published online 2020 Aug 31. doi: 10.1038/s41598-020-71241-1
PMCID:
PMC7459279
AbstractArticlePDF–1017K
12.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
13.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
14.
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders
Siwei Chen, Robert Fragoza, Lambertus Klei, Yuan Liu, Jiebiao Wang, Kathryn Roeder, Bernie Devlin, Haiyuan Yu
Nat Genet. Author manuscript; available in PMC 2019 Jul 1.
Published in final edited form as: Nat Genet. 2018 Jul; 50(7): 1032–1040. Published online 2018 Jun 11. doi: 10.1038/s41588-018-0130-z
PMCID:
PMC6314957
AbstractArticlePDF–1.3M
15.
Inhibition of low-density lipoprotein receptor degradation with a cyclic peptide that disrupts the homodimerization of IDOL E3 ubiquitin ligase
Eilidh K. Leitch, Nagarajan Elumalai, Maria Fridén-Saxin, Göran Dahl, Paul Wan, Paul Clarkson, Eric Valeur, Garry Pairaudeau, Helen Boyd, Ali Tavassoli
Chem Sci. 2018 Jul 21; 9(27): 5957–5966. Published online 2018 Jun 26. doi: 10.1039/c8sc01186a
PMCID:
PMC6050537
AbstractArticlePDF–667K
16.
CNPY2 inhibits MYLIP-mediated AR protein degradation in prostate cancer cells
Saya Ito, Akihisa Ueno, Takashi Ueda, Hideo Nakagawa, Hidefumi Taniguchi, Naruhiro Kayukawa, Atsuko Fujihara-Iwata, Fumiya Hongo, Koji Okihara, Osamu Ukimura
Oncotarget. 2018 Apr 3; 9(25): 17645–17655. Published online 2018 Apr 3. doi: 10.18632/oncotarget.24824
PMCID:
PMC5915145
AbstractArticlePDF–2.7M
17.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
18.
TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions
Charles A. S. Banks, Gina Boanca, Zachary T. Lee, Cassandra G. Eubanks, Gaye L. Hattem, Allison Peak, Lauren E. Weems, Juliana J. Conkright, Laurence Florens, Michael P. Washburn
Mol Cell Proteomics. 2016 Nov; 15(11): 3435–3449. Published online 2016 Sep 8. doi: 10.1074/mcp.M116.060509
PMCID:
PMC5098041
AbstractArticlePDF–2.1M
19.
RP1-13D10.2 Is a Novel Modulator of Statin-Induced Changes in Cholesterol
Katrina Mitchel, Elizabeth Theusch, Celia Cubitt, Andréa C. Dosé, Kristen Stevens, Devesh Naidoo, Marisa W. Medina
Circ Cardiovasc Genet. Author manuscript; available in PMC 2017 Jun 1.
Published in final edited form as: Circ Cardiovasc Genet. 2016 Jun; 9(3): 223–230. Published online 2016 Apr 12. doi: 10.1161/CIRCGENETICS.115.001274
PMCID:
PMC4917428
AbstractArticlePDF–585K
20.
Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake
Jessica Kristine Nelson, Emma Clare Laura Cook, Anke Loregger, Marten Anne Hoeksema, Saskia Scheij, Igor Kovacevic, Peter Lodewijk Hordijk, Huib Ovaa, Noam Zelcer
J Biol Chem. 2016 Feb 26; 291(9): 4813–4825. Published online 2015 Dec 30. doi: 10.1074/jbc.M115.698688
PMCID:
PMC4813502
AbstractArticlePDF–1.9M

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