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Select item 106568211.

Loss of p53-DREAM-mediated repression of cell cycle genes as a driver of lymph node metastasis in head and neck cancer

Kevin Brennan, Almudena Espín-Pérez, Serena Chang, Nikita Bedi, Saumyaa Saumyaa, June Ho Shin, Sylvia K. Plevritis, Olivier Gevaert, John B. Sunwoo, Andrew J. Gentles

Genome Med. 2023; 15: 98. Published online 2023 Nov 17. doi: 10.1186/s13073-023-01236-w

PMCID:: PMC10656821

Abstract Article PDF–5.8M

Select item 102523072.

Emerging Role of DREAM in Healthy Brain and Neurological Diseases

Pasquale Molinaro, Luca Sanguigno, Antonella Casamassa, Valeria Valsecchi, Rossana Sirabella, Giuseppe Pignataro, Lucio Annunziato, Luigi Formisano

Int J Mol Sci. 2023 Jun; 24(11): 9177. Published online 2023 May 24. doi: 10.3390/ijms24119177

PMCID:: PMC10252307

Abstract Article PDF–3.2M

Select item 87196433.

Neutrophil DREAM promotes neutrophil recruitment in vascular inflammation

Jing Li, Tripti Kumari, Andrew Barazia, Vishwanath Jha, Si-Yeon Jeong, Amber Olson, Mijeong Kim, Bum-Kyu Lee, Vijayprakash Manickam, Zhimin Song, Regina Clemens, Babak Razani, Jonghwan Kim, Mary C. Dinauer, Jaehyung Cho

J Exp Med. 2022 Jan 3; 219(1): e20211083. Published online 2021 Nov 9. doi: 10.1084/jem.20211083

PMCID:: PMC8719643

Abstract Article PDF–6.4M

Select item 80522884.

PAF remodels the DREAM complex to bypass cell quiescence and promote lung tumorigenesis

Moon Jong Kim, Christopher Cervantes, Youn-Sang Jung, Xiaoshan Zhang, Jie Zhang, Sung Ho Lee, Sohee Jun, Larisa Litovchick, Wenqi Wang, Junjie Chen, Bingliang Fang, Jae-Il Park

Mol Cell. 2021 Apr 15; 81(8): 1698–1714.e6. doi: 10.1016/j.molcel.2021.02.001

PMCID:: PMC8052288

Abstract Article

Select item 74435055.

Modulation of Kv4.2/KChIP3 interaction by the ceroid lipofuscinosis neuronal 3 protein CLN3

Carolin Seifert, Stephan Storch, Robert Bähring

J Biol Chem. 2020 Aug 21; 295(34): 12099–12110. Published online 2020 Jul 7. doi: 10.1074/jbc.RA120.013828

PMCID:: PMC7443505

Abstract Article PDF–1.4M

Select item 71699836.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 67587377.

PKA Modulation of Kv4.2-Encoded A-Type Potassium Channels Requires Formation of a Supramolecular Complex

Laura A. Schrader, Anne E. Anderson, Amber Mayne, Paul J. Pfaffinger, John David Sweatt

J Neurosci. 2002 Dec 1; 22(23): 10123–10133. doi: 10.1523/JNEUROSCI.22-23-10123.2002

PMCID:: PMC6758737

Abstract Article PDF–503K

Select item 67258798.

Downstream Regulatory Element Antagonist Modulator Regulates Ca²⁺ Homeostasis and Viability in Cerebellar Neurons

Rosa Gomez-Villafuertes, Begoña Torres, Jorge Barrio, Magali Savignac, Nadia Gabellini, Federico Rizzato, Belen Pintado, Alfonso Gutierrez-Adan, Britt Mellström, Ernesto Carafoli, Jose R. Naranjo

J Neurosci. 2005 Nov 23; 25(47): 10822–10830. doi: 10.1523/JNEUROSCI.3912-05.2005

PMCID:: PMC6725879

Abstract Article PDF–713K

Select item 65865199.

Cyclin D-CDK4 relieves cooperative repression of proliferation and cell cycle gene expression by DREAM and RB.

Amy E. Schade, Matthew G. Oser, Hilary E. Nicholson, James A. DeCaprio

Oncogene. Author manuscript; available in PMC 2019 Sep 4.

Published in final edited form as: Oncogene. 2019 Jun; 38(25): 4962–4976. Published online 2019 Mar 4. doi: 10.1038/s41388-019-0767-9

PMCID:: PMC6586519

Abstract Article PDF–1.9M

Select item 624297210.

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

Bieke Decaesteker, Geertrui Denecker, Christophe Van Neste, Emmy M. Dolman, Wouter Van Loocke, Moritz Gartlgruber, Carolina Nunes, Fanny De Vloed, Pauline Depuydt, Karen Verboom, Dries Rombaut, Siebe Loontiens, Jolien De Wyn, Waleed M. Kholosy, Bianca Koopmans, Anke H. W. Essing, Carl Herrmann, Daniel Dreidax, Kaat Durinck, Dieter Deforce, Filip Van Nieuwerburgh, Anton Henssen, Rogier Versteeg, Valentina Boeva, Gudrun Schleiermacher, Johan van Nes, Pieter Mestdagh, Suzanne Vanhauwaert, Johannes H. Schulte, Frank Westermann, Jan J. Molenaar, Katleen De Preter, Frank Speleman

Nat Commun. 2018; 9: 4866. Published online 2018 Nov 19. doi: 10.1038/s41467-018-06699-9

PMCID:: PMC6242972

Abstract Article PDF–13M

Select item 616705111.

KChIP3 coupled to Ca²⁺ oscillations exerts a tonic brake on baseline mucin release in the colon

Gerard Cantero-Recasens, Cristian M Butnaru, Miguel A Valverde, José R Naranjo, Nathalie Brouwers, Vivek Malhotra

eLife. 2018; 7: e39729. Published online 2018 Oct 1. doi: 10.7554/eLife.39729

PMCID:: PMC6167051

Abstract Article PDF–4.3M

Select item 616668212.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 573047413.

SmgGDS is a transient nucleolar protein that protects cells from nucleolar stress and promotes the cell cycle by regulating DREAM complex gene expression

P Gonyo, C Bergom, A C Brandt, S-W Tsaih, Y Sun, T M Bigley, E L Lorimer, S S Terhune, H Rui, M J Flister, R M Long, C L Williams

Oncogene. 2017 Dec 14; 36(50): 6873–6883. Published online 2017 Aug 14. doi: 10.1038/onc.2017.280

PMCID:: PMC5730474

Abstract Article PDF–3.6M

Select item 555168314.

HDX MS reveals calcium binding properties and allosteric regulation of downstream regulatory element antagonist modulator (DREAM)

Jun Zhang, Jing Li, Theodore A. Craig, Michael L. Gross

Biochemistry. Author manuscript; available in PMC 2018 Jul 18.

Published in final edited form as: Biochemistry. 2017 Jul 18; 56(28): 3523–3530. Published online 2017 Jul 3. doi: 10.1021/acs.biochem.7b00100

PMCID:: PMC5551683

Abstract Article PDF–572K

Select item 549522515.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 545398316.

Human papilloma virus E7 oncoprotein abrogates the p53-p21-DREAM pathway

Martin Fischer, Sigrid Uxa, Clara Stanko, Thomas M. Magin, Kurt Engeland

Sci Rep. 2017; 7: 2603. Published online 2017 Jun 1. doi: 10.1038/s41598-017-02831-9

PMCID:: PMC5453983

Abstract Article PDF–1.5M

Select item 541928017.

The DREAM Protein Is Associated with Thyroid Enlargement and Nodular Development

Marcos Rivas, Britt Mellström, Begoña Torres, Gaetano Cali, Alfonso M. Ferrara, Daniela Terracciano, Mariastella Zannini, Gabriella Morreale de Escobar, Jose R. Naranjo

Mol Endocrinol. June 1, 2009; 23(6): 862–870. doi: 10.1210/me.2008-0466

PMCID:: PMC5419280

Abstract Article

Select item 499486518.

Integration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle gene regulatory networks

Martin Fischer, Patrick Grossmann, Megha Padi, James A. DeCaprio

Nucleic Acids Res. 2016 Jul 27; 44(13): 6070–6086. Published online 2016 Jun 8. doi: 10.1093/nar/gkw523

PMCID:: PMC4994865

Abstract Article PDF–9.4M

Select item 484875819.

An inter‐species protein–protein interaction network across vast evolutionary distance

Quan Zhong, Samuel J Pevzner, Tong Hao, Yang Wang, Roberto Mosca, Jörg Menche, Mikko Taipale, Murat Taşan, Changyu Fan, Xinping Yang, Patrick Haley, Ryan R Murray, Flora Mer, Fana Gebreab, Stanley Tam, Andrew MacWilliams, Amélie Dricot, Patrick Reichert, Balaji Santhanam, Lila Ghamsari, Michael A Calderwood, Thomas Rolland, Benoit Charloteaux, Susan Lindquist, Albert‐László Barabási, David E Hill, Patrick Aloy, Michael E Cusick, Yu Xia, Frederick P Roth, Marc Vidal

Mol Syst Biol. 2016 Apr; 12(4): 865. Published online 2016 Apr 23. doi: 10.15252/msb.20156484

PMCID:: PMC4848758

Abstract Article PDF–2.1M

Select item 470569020.

The p53-p21-DREAM-CDE/CHR pathway regulates G₂/M cell cycle genes

Martin Fischer, Marianne Quaas, Lydia Steiner, Kurt Engeland

Nucleic Acids Res. 2016 Jan 8; 44(1): 164–174. Published online 2015 Sep 17. doi: 10.1093/nar/gkv927

PMCID:: PMC4705690

Abstract Article PDF–2.1M

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