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Select item 105827291.

GLUT5: structure, functions, diseases and potential applications

Aqian Song, Yuanpeng Mao, Hongshan Wei

Acta Biochim Biophys Sin (Shanghai) 2023 Oct 25; 55(10): 1519–1538. Published online 2023 Sep 7. doi: 10.3724/abbs.2023158

PMCID:: PMC10582729

Abstract Article PDF–2.7M

Select item 103756482.

Fructose promotes angiogenesis by improving vascular endothelial cell function and upregulating VEGF expression in cancer cells

Yanfen Cui, Hui Liu, Zhaosong Wang, He Zhang, Jianfei Tian, Zhiyong Wang, Weijie Song, Hui Guo, Liming Liu, Ruinan Tian, Xiaoyan Zuo, Sixin Ren, Fei Zhang, Ruifang Niu

J Exp Clin Cancer Res. 2023; 42: 184. Published online 2023 Jul 28. doi: 10.1186/s13046-023-02765-3

PMCID:: PMC10375648

Abstract Article PDF–18M

Select item 89853003.

Gene variants of the SLC2A5 gene encoding GLUT5, the major fructose transporter, do not contribute to clinical presentation of acquired fructose malabsorption

Irina Taneva, Dorothee Grumann, Dietmar Schmidt, Elina Taneva, Ulrike von Arnim, Thomas Ansorge, Thomas Wex

BMC Gastroenterol. 2022; 22: 167. Published online 2022 Apr 6. doi: 10.1186/s12876-022-02244-7

PMCID:: PMC8985300

Abstract Article PDF–918K

Select item 89345544.

Serum Iba-1, GLUT5, and TSPO in Patients With Diabetic Retinopathy: New Biomarkers for Early Retinal Neurovascular Alterations? A Pilot Study

Maria Consiglia Trotta, Carlo Gesualdo, Francesco Petrillo, Giancuomo Cavasso, Alberto Della Corte, Giovanbattista D'Amico, Anca Hermenean, Francesca Simonelli, Settimio Rossi

Transl Vis Sci Technol. 2022 Mar; 11(3): 16. Published online 2022 Mar 14. doi: 10.1167/tvst.11.3.16

PMCID:: PMC8934554

Abstract Article PDF–1.8M

Select item 84839045.

Lianxiang Luo, Jiating Su, Yushi Zheng, Fangfang Huang, Riming Huang, Hui Luo

J Immunol Res. 2021; 2021: 9938397. Published online 2021 Sep 23. doi: 10.1155/2021/9938397

PMCID:: PMC8483904

Abstract Article PDF–4.3M

Select item 84056476.

S100P contributes to promoter demethylation and transcriptional activation of SLC2A5 to promote metastasis in colorectal cancer

Mingdao Lin, Yuan Fang, Zhenkang Li, Yongsheng Li, Xiaochuang Feng, Yizhi Zhan, Yuwen Xie, Yuechen Liu, Zehao Liu, Guoxin Li, Zhiyong Shen, Haijun Deng

Br J Cancer. 2021 Aug 31; 125(5): 734–747. Published online 2021 Jun 29. doi: 10.1038/s41416-021-01306-z

PMCID:: PMC8405647

Abstract Article PDF–5.9M

Select item 82538457.

Identification of new GLUT2-selective inhibitors through in silico ligand screening and validation in eukaryotic expression systems

Sina Schmidl, Oleg Ursu, Cristina V. Iancu, Mislav Oreb, Tudor I. Oprea, Jun-yong Choe

Sci Rep. 2021; 11: 13751. Published online 2021 Jul 2. doi: 10.1038/s41598-021-93063-5

PMCID:: PMC8253845

Abstract Article PDF–4.3M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 71699839.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 709966910.

The Solute Carrier Family 2 Genes Are Potential Prognostic Biomarkers in Acute Myeloid Leukemia

Binbin Lai, Yanli Lai, Yanli Zhang, Miao Zhou, Lixia Sheng, Guifang OuYang

Technol Cancer Res Treat. 2020; 19: 1533033819894308. Published online 2020 Jan 10. doi: 10.1177/1533033819894308

PMCID:: PMC7099669

Abstract Article PDF–476K

Select item 709878911.

GLUT5-mediated fructose utilization drives lung cancer growth by stimulating fatty acid synthesis and AMPK/mTORC1 signaling

Wen-Lian Chen, Xing Jin, Mingsong Wang, Dan Liu, Qin Luo, Hechuan Tian, Lili Cai, Lifei Meng, Rui Bi, Lei Wang, Xiao Xie, Guanzhen Yu, Lihui Li, Changsheng Dong, Qiliang Cai, Wei Jia, Wenyi Wei, Lijun Jia

JCI Insight. 2020 Feb 13; 5(3): e131596. Published online 2020 Feb 13. doi: 10.1172/jci.insight.131596

PMCID:: PMC7098789

Abstract Article PDF–11M

Select item 659492612.

Identification of the fructose transporter GLUT5 (SLC2A5) as a novel target of nuclear receptor LXR

Irene Zwarts, Tim van Zutphen, Janine K. Kruit, Weilin Liu, Maaike H. Oosterveer, Henkjan J. Verkade, N. Henriette Uhlenhaut, Johan W. Jonker

Sci Rep. 2019; 9: 9299. Published online 2019 Jun 26. doi: 10.1038/s41598-019-45803-x

PMCID:: PMC6594926

Abstract Article PDF–1.5M

Select item 580877113.

Identification of essential amino acids for glucose transporter 5 (GLUT5)-mediated fructose transport

Karolin Ebert, Maren Ewers, Ina Bisha, Simone Sander, Tanja Rasputniac, Hannelore Daniel, Iris Antes, Heiko Witt

J Biol Chem. 2018 Feb 9; 293(6): 2115–2124. Published online 2017 Dec 19. doi: 10.1074/jbc.RA117.001442

PMCID:: PMC5808771

Abstract Article PDF–1.8M

Select item 553161114.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 460752315.

Natural Selection at the Brush-Border: Adaptations to Carbohydrate Diets in Humans and Other Mammals

Chiara Pontremoli, Alessandra Mozzi, Diego Forni, Rachele Cagliani, Uberto Pozzoli, Giorgia Menozzi, Jacopo Vertemara, Nereo Bresolin, Mario Clerici, Manuela Sironi

Genome Biol Evol. 2015 Sep; 7(9): 2569–2584. Published online 2015 Sep 11. doi: 10.1093/gbe/evv166

PMCID:: PMC4607523

Abstract Article PDF–1.9M

Select item 400459816.

Systematic identification of pathological lamin A interactors

Travis A. Dittmer, Nidhi Sahni, Nard Kubben, David E. Hill, Marc Vidal, Rebecca C. Burgess, Vassilis Roukos, Tom Misteli

Mol Biol Cell. 2014 May 1; 25(9): 1493–1510. doi: 10.1091/mbc.E14-02-0733

PMCID:: PMC4004598

Abstract Article PDF–3.5M

Select item 377350517.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

Select item 354485418.

Impact of Genetic Polymorphisms of SLC2A2, SLC2A5, and KHK on Metabolic Phenotypes in Hypertensive Individuals

MyPhuong T. Le, Maximilian T. Lobmeyer, Marcus Campbell, Jing Cheng, Zhiying Wang, Stephen T. Turner, Arlene B. Chapman, Eric Boerwinkle, John G. Gums, Yan Gong, Richard J. Johnson, Julie A. Johnson

PLoS One. 2013; 8(1): e52062. Published online 2013 Jan 14. doi: 10.1371/journal.pone.0052062

PMCID:: PMC3544854

Abstract Article PDF–240K

Select item 326170819.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67

Correction in:: Mol Syst Biol. 2017 Dec; 13(12): 965.

PMCID:: PMC3261708

Abstract Article PDF–2.0M

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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