PMC Links for GEO Profiles (Select 85268910) - PMC

Sheng Zhong, Quanwei Guo, Xiaona Chen, Xiaomin Luo, Yufei Long, Tuotuo Chong, Ming Ye, Hui He, Anwei Lu, Keyi Ao, Minuo Yin, Aimin Xu, Xin Li, Yi Hao, Xia Guo

Int J Biol Sci. 2024; 20(3): 916–936. Published online 2024 Jan 12. doi: 10.7150/ijbs.87203

PMCID:: PMC10797697

Abstract Article PDF–13M

Select item 106244294.

A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer’s disease

Megan E. Jones, Johanna Büchler, Tom Dufor, Ernest Palomer, Samuel Teo, Nuria Martin-Flores, Katharina Boroviak, Emmanouil Metzakopian, Alasdair Gibb, Patricia C. Salinas

Sci Adv. 2023 Jan; 9(2): eabo7421. Published online 2023 Jan 13. doi: 10.1126/sciadv.abo7421

PMCID:: PMC10624429

Abstract Article PDF–1.8M

Select item 102374225.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101937316.

LRP5-/6 gene polymorphisms and its association with risk of abnormal bone mass in postmenopausal women

Jun Li, Zebing Liu, Yanxia Ren, Han Shao, Siyuan Li

J Orthop Surg Res. 2023; 18: 369. Published online 2023 May 18. doi: 10.1186/s13018-023-03829-y

PMCID:: PMC10193731

Abstract Article PDF–988K

Select item 98723977.

LRP6/filamentous-actin signaling facilitates osteogenic commitment in mechanically induced periodontal ligament stem cells

Jixiao Wang, Huiqi Yang, Xiaobei Ma, Jiani Liu, Lan Li, Lei Chen, Fulan Wei

Cell Mol Biol Lett. 2023; 28: 7. Published online 2023 Jan 24. doi: 10.1186/s11658-023-00420-5

PMCID:: PMC9872397

Abstract Article PDF–9.9M

Select item 95684788.

An LRP6 mutation (Arg360His) associated with low bone mineral density but not cardiovascular events in a Caucasian family

Nuria Puente, Ana I. Vega, José L. Hernandez, Jose L. Fernandez-Luna, Jose A. Riancho

Osteoporos Int. 2022; 33(11): 2445–2448. Published online 2022 Jul 15. doi: 10.1007/s00198-022-06494-9

PMCID:: PMC9568478

Abstract Article PDF–564K

Select item 95347619.

Antibody targeting of E3 ubiquitin ligases for receptor degradation

Hadir Marei, Wen-Ting K. Tsai, Yee-Seir Kee, Karen Ruiz, Jieyan He, Chris Cox, Tao Sun, Sai Penikalapati, Pankaj Dwivedi, Meena Choi, David Kan, Pablo Saenz-Lopez, Kristel Dorighi, Pamela Zhang, Yvonne T. Kschonsak, Noelyn Kljavin, Dhara Amin, Ingrid Kim, Andrew G. Mancini, Thao Nguyen, Chunling Wang, Eric Janezic, Alexander Doan, Elaine Mai, Hongkang Xi, Chen Gu, Melanie Heinlein, Brian Biehs, Jia Wu, Isabelle Lehoux, Seth Harris, Laetitia Comps-Agrar, Dhaya Seshasayee, Frederic J. de Sauvage, Matthew Grimmer, Jing Li, Nicholas J. Agard, Felipe de Sousa e Melo

Nature. 2022; 610(7930): 182–189. Published online 2022 Sep 21. doi: 10.1038/s41586-022-05235-6

PMCID:: PMC9534761

Abstract Article PDF–18M

Select item 948193310.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 923162311.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 911973612.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 887872413.

circ-LRP6 contributes to osteosarcoma progression by regulating the miR-141-3p/HDAC4/HMGB1 axis

Yali Yu, Guixiang Dong, Zijun Li, Yan Zheng, Zhisong Shi, Guanghui Wang

Int J Oncol. 2022 Apr; 60(4): 38. Published online 2022 Feb 23. doi: 10.3892/ijo.2022.5328

PMCID:: PMC8878724

Abstract Article PDF–1.2M

Select item 882889514.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 869101715.

MicroRNA-513c-5p is involved in the pathogenesis of preeclampsia by regulating of low-density lipoprotein receptor-associated protein 6

Qian Zhou, Hongyan Li, Yan Zhang, Wei Peng, Haiyan Hou, Mengqi Gu, Fengyuan Zhang, Xietong Wang, Xiao Gu, Lei Li

BMC Pregnancy Childbirth. 2021; 21: 837. Published online 2021 Dec 20. doi: 10.1186/s12884-021-04069-w

PMCID:: PMC8691017

Abstract Article PDF–2.1M

Select item 849540616.

Lrp6 Genotype affects Individual Susceptibility to Nonalcoholic Fatty Liver Disease and Silibinin Therapeutic Response via Wnt/β-catenin-Cyp2e1 Signaling

Li-Jie Chen, Xiu-Xian Lin, Jing Guo, Ying Xu, Song-Xia Zhang, Dan Chen, Qing Zhao, Jian Xiao, Guang-Hui Lian, Shi-Fang Peng, Dong Guo, Hong Yang, Yan Shu, Hong-Hao Zhou, Wei Zhang, Yao Chen

Int J Biol Sci. 2021; 17(14): 3936–3953. Published online 2021 Sep 21. doi: 10.7150/ijbs.63732

PMCID:: PMC8495406

Abstract Article PDF–2.5M

Select item 849474117.

Transmembrane protein 97 exhibits oncogenic properties via enhancing LRP6-mediated Wnt signaling in breast cancer

Huifang Zhu, Zijie Su, Jiong Ning, Liang Zhou, Lifeng Tan, Sapna Sayed, Jiaxing Song, Zhongyuan Wang, Huan Li, Qi Sun, Shanshan Liu, Ou Sha, Feng Leng, Xianxiong Chen, Desheng Lu

Cell Death Dis. 2021 Oct; 12(10): 912. Published online 2021 Oct 6. doi: 10.1038/s41419-021-04211-8