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Select item 103990111.

Novel mutations in CYBB Gene Cause X-linked chronic Granulomatous Disease in Pakistani patients

Irum Gul, Taj Ali Khan, Noor ul Akbar, Naila Gul, Rehman Ali, Shahid Niaz Khan

Ital J Pediatr. 2023; 49: 95. Published online 2023 Aug 2. doi: 10.1186/s13052-023-01496-7

PMCID:: PMC10399011

Abstract Article PDF–1.7M

Select item 103170232.

TIAM1–RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy

Renu A. Kowluru, Anjaneyulu Kowluru, Rajakrishnan Veluthakal, Ghulam Mohammad, Ismail Syed, Julia M. Santos, Manish Mishra

Diabetologia. Author manuscript; available in PMC 2023 Jul 3.

Published in final edited form as: Diabetologia. 2014 May; 57(5): 1047–1056. Published online 2014 Feb 20. doi: 10.1007/s00125-014-3194-z

PMCID:: PMC10317023

Abstract Article PDF–1.3M

Select item 101782613.

NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via Nrf2/SOD2 Modulation

I-Chang Su, Yu-Kai Su, Syahru Agung Setiawan, Vijesh Kumar Yadav, Iat-Hang Fong, Chi-Tai Yeh, Chien-Min Lin, Heng-Wei Liu

Int J Mol Sci. 2023 May; 24(9): 7706. Published online 2023 Apr 22. doi: 10.3390/ijms24097706

PMCID:: PMC10178261

Abstract Article PDF–6.6M

Select item 98677624.

Crocetin antagonizes parthanatos in ischemic stroke via inhibiting NOX2 and preserving mitochondrial hexokinase-I

Hao Wu, Ying Li, Qian Zhang, Hanxun Wang, Wenyu Xiu, Pu Xu, Yujie Deng, Wanxu Huang, Dan Ohtan Wang

Cell Death Dis. 2023 Jan; 14(1): 50. Published online 2023 Jan 21. doi: 10.1038/s41419-023-05581-x

PMCID:: PMC9867762

Abstract Article PDF–4.9M

Select item 98202185.

TRPC3-Nox2 Protein Complex Formation Increases the Risk of SARS-CoV-2 Spike Protein-Induced Cardiomyocyte Dysfunction through ACE2 Upregulation

Yuri Kato, Kazuhiro Nishiyama, Jae Man Lee, Yuko Ibuki, Yumiko Imai, Takamasa Noda, Noriho Kamiya, Takahiro Kusakabe, Yasunari Kanda, Motohiro Nishida

Int J Mol Sci. 2023 Jan; 24(1): 102. Published online 2022 Dec 21. doi: 10.3390/ijms24010102

PMCID:: PMC9820218

Abstract Article PDF–1.5M

Select item 96258476.

NOX2 and NOX5 are increased in cardiac microvascular endothelium of deceased COVID-19 patients

Zhu Jiang, Linghe Wu, Britt van der Leeden, Albert C. van Rossum, Hans W.M. Niessen, Paul A.J. Krijnen

Int J Cardiol. 2023 Jan 1; 370: 454–462. Published online 2022 Nov 2. doi: 10.1016/j.ijcard.2022.10.172

PMCID:: PMC9625847

Abstract Article PDF–2.2M

Select item 96145397.

The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of acute myeloid leukemias

Rosa Paolillo, Mathias Boulanger, Pierre Gâtel, Ludovic Gabellier, Marion De Toledo, Denis Tempé, Rawan Hallal, Dana Akl, Jérôme Moreaux, Hayeon Baik, Elise Gueret, Christian Recher, Jean-Emmanuel Sarry, Guillaume Cartron, Marc Piechaczyk, Guillaume Bossis

Haematologica. 2022 Nov 1; 107(11): 2562–2575. Published online 2022 Feb 17. doi: 10.3324/haematol.2021.279889

PMCID:: PMC9614539

Abstract Article PDF–2.6M

Select item 95685518.

Structure of the core human NADPH oxidase NOX2

Sigrid Noreng, Naruhisa Ota, Yonglian Sun, Hoangdung Ho, Matthew Johnson, Christopher P. Arthur, Kellen Schneider, Isabelle Lehoux, Christopher W. Davies, Kyle Mortara, Kit Wong, Dhaya Seshasayee, Matthieu Masureel, Jian Payandeh, Tangsheng Yi, James T. Koerber

Nat Commun. 2022; 13: 6079. Published online 2022 Oct 14. doi: 10.1038/s41467-022-33711-0

PMCID:: PMC9568551

Abstract Article PDF–2.6M

Select item 94861099.

Regulation of Derlin-1-mediated degradation of NADPH oxidase partner p22^phox by thiol modification

Kei Miyano, Shuichiro Okamoto, Mizuho Kajikawa, Takuya Kiyohara, Chikage Kawai, Akira Yamauchi, Futoshi Kuribayashi

Redox Biol. 2022 Oct; 56: 102479. Published online 2022 Sep 13. doi: 10.1016/j.redox.2022.102479

PMCID:: PMC9486109

Abstract Article PDF–19M

Select item 926660810.

Construction of three‐gene‐based prognostic signature and analysis of immune cells infiltration in children and young adults with B‐acute lymphoblastic leukemia

Chunli Xiang, Jie Wu, Liang Yu

Mol Genet Genomic Med. 2022 Jul; 10(7): e1964. Published online 2022 May 23. doi: 10.1002/mgg3.1964

PMCID:: PMC9266608

Abstract Article PDF–16M

Select item 862557111.

Quercetin Prevents LPS-Induced Oxidative Stress and Inflammation by Modulating NOX2/ROS/NF-kB in Lung Epithelial Cells

Ok-Joo Sul, Seung Won Ra

Molecules. 2021 Nov; 26(22): 6949. Published online 2021 Nov 17. doi: 10.3390/molecules26226949

PMCID:: PMC8625571

Abstract Article PDF–1.9M

Select item 853548712.

Chronic Granulomatous Disease and Myelodysplastic Syndrome in a Patient with a Novel Mutation in CYBB

Bárbara C. S. Reis, Daniela P. Cunha, Ana Paula S. Bueno, Flavia A. A. Carvalho, Juliana Dutra, Fabiana V. Mello, Maria Cecília Menks Ribeiro, Cristiane B. Milito, Elaine Sobral da Costa, Zilton Vasconcelos

Genes (Basel) 2021 Oct; 12(10): 1476. Published online 2021 Sep 23. doi: 10.3390/genes12101476

PMCID:: PMC8535487

Abstract Article PDF–1.3M

Select item 847980113.

Inducibility, but not stability, of atrial fibrillation is increased by NOX2 overexpression in mice

Alexandra S Mighiu, Alice Recalde, Klemen Ziberna, Ricardo Carnicer, Jakub Tomek, Gil Bub, Alison C Brewer, Sander Verheule, Ajay M Shah, Jillian N Simon, Barbara Casadei

Cardiovasc Res. 2021 Oct 1; 117(11): 2354–2364. Published online 2021 Jan 23. doi: 10.1093/cvr/cvab019

PMCID:: PMC8479801

Abstract Article PDF–1.2M

Select item 843789314.

Therapeutic hypothermia augments the restorative effects of PKC-β and Nox2 inhibition on an in vitro model of human blood–brain barrier

Rais Reskiawan A. Kadir, Mansour Alwjwaj, Zoe McCarthy, Ulvi Bayraktutan

Metab Brain Dis. 2021; 36(7): 1817–1832. Published online 2021 Aug 16. doi: 10.1007/s11011-021-00810-8

PMCID:: PMC8437893

Abstract Article PDF–2.7M

Select item 835349215.

Rac-dependent feedforward autoactivation of NOX2 leads to oxidative burst

Hanh My Hoang, Hope Elizabeth Johnson, Jongyun Heo

J Biol Chem. 2021 Aug; 297(2): 100982. Published online 2021 Jul 20. doi: 10.1016/j.jbc.2021.100982

PMCID:: PMC8353492

Abstract Article PDF–2.4M

Select item 816503016.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 789153017.

Identification of Cytochrome b‐245, beta‐chain gene mutations, and clinical presentations in Iranian patients with X‐linked chronic granulomatous disease

Atefeh Heydari, Farhad Abolnezhadian, Mahnaz Sadeghi‐Shabestari, Alihossein Saberi, Ahmad Shamsizadeh, Ata A. Ghadiri, Pegah Ghandil

J Clin Lab Anal. 2021 Feb; 35(2): e23637. Published online 2020 Oct 23. doi: 10.1002/jcla.23637

PMCID:: PMC7891530

Abstract Article PDF–1.0M

Select item 785540718.

Expanding the clinical phenotype of chronic granulomatous disease: a female patient with a de novo mutation in CYBB

Eveline Y. Wu, Hye Sun Kuehn, Sergio D. Rosenzweig, Ivona Aksentijevich, Diana B. McShane

J Clin Immunol. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: J Clin Immunol. 2021 Jan; 41(1): 224–226. Published online 2020 Oct 1. doi: 10.1007/s10875-020-00877-5

PMCID:: PMC7855407

Article PDF–154K

Select item 780645019.

Clinical, functional and genetic characterization of 16 patients suffering from chronic granulomatous disease variants – identification of 11 novel mutations in CYBB

M. Mollin, S. Beaumel, B. Vigne, J. Brault, N. Roux‐Buisson, J. Rendu, V. Barlogis, G. Catho, C. Dumeril, F. Fouyssac, D. Monnier, V. Gandemer, M. Revest, J.‐P. Brion, C. Bost‐Bru, E. Jeziorski, L. Eitenschenck, C. Jarrasse, S. Drillon Haus, M. Houachée‐Chardin, M. Hancart, G. Michel, Y. Bertrand, D. Plantaz, J. Kelecic, R. Traberg, L. Kainulainen, J. Fauré, F. Fieschi, M. J. Stasia

Clin Exp Immunol. 2021 Feb; 203(2): 247–266. Published online 2020 Oct 12. doi: 10.1111/cei.13520

PMCID:: PMC7806450

Abstract Article PDF–1.2M

Select item 772150620.

NOX2-Derived Reactive Oxygen Species in Cancer

Hanna Grauers Wiktorin, Ebru Aydin, Kristoffer Hellstrand, Anna Martner

Oxid Med Cell Longev. 2020; 2020: 7095902. Published online 2020 Nov 27. doi: 10.1155/2020/7095902

PMCID:: PMC7721506

Abstract Article PDF–1005K

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