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Select item 95901441.

Downregulation of TUSC3 promotes EMT and hepatocellular carcinoma progression through LIPC/AKT axis

Ruxia Deng, Xiansheng Lu, Chang Hong, Rui Cai, Ping Wang, Le Xiong, Xiaoyu Wang, Qiaoyu Chen, Jie Lin

J Transl Med. 2022; 20: 485. Published online 2022 Oct 23. doi: 10.1186/s12967-022-03690-3

PMCID:: PMC9590144

Abstract Article PDF–2.7M

Select item 94396362.

Identification of a Gain-of-Function LIPC Variant as a Novel Cause of Familial Combined Hypocholesterolemia

Wieneke Dijk, Mathilde Di Filippo, Sander Kooijman, Robin van Eenige, Antoine Rimbert, Amandine Caillaud, Aurélie Thedrez, Lucie Arnaud, Amanda Pronk, Damien Garçon, Thibaud Sotin, Pierre Lindenbaum, Enrique Ozcariz Garcia, Jean-Paul Pais de Barros, Laurence Duvillard, Karim Si-Tayeb, Nuria Amigo, Jean-Yves Le Questel, Patrick C.N. Rensen, Cédric Le May, Philippe Moulin, Bertrand Cariou

Circulation. 2022 Sep 6; 146(10): 724–739. Published online 2022 Jul 28. doi: 10.1161/CIRCULATIONAHA.121.057978

PMCID:: PMC9439636

Abstract Article PDF–1.5M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79108594.

Functional Haplotype of LIPC Induces Triglyceride-Mediated Suppression of HDL-C Levels According to Genome-Wide Association Studies

Yu-Huang Liao, Leay-Kiaw Er, Semon Wu, Yu-Lin Ko, Ming-Sheng Teng

Genes (Basel) 2021 Feb; 12(2): 148. Published online 2021 Jan 22. doi: 10.3390/genes12020148

PMCID:: PMC7910859

Abstract Article PDF–1.2M

Select item 75306575.

A study of associations between CUBN, HNF1A, and LIPC gene polymorphisms and coronary artery disease

Han Sung Park, In Jai Kim, Eun Gyo Kim, Chang Soo Ryu, Jeong Yong Lee, Eun Ju Ko, Hyeon Woo Park, Jung Hoon Sung, Nam Keun Kim

Sci Rep. 2020; 10: 16294. Published online 2020 Oct 1. doi: 10.1038/s41598-020-73048-6

PMCID:: PMC7530657

Abstract Article PDF–1.1M

Select item 70168646.

The Effect of Haplotypes in the CETP and LIPC Genes on the Triglycerides to HDL-C Ratio and Its Components in the Roma and Hungarian General Populations

Peter Piko, Szilvia Fiatal, Nardos Abebe Werissa, Bayu Begashaw Bekele, Gabor Racz, Zsigmond Kosa, Janos Sandor, Roza Adany

Genes (Basel) 2020 Jan; 11(1): 56. Published online 2020 Jan 3. doi: 10.3390/genes11010056

PMCID:: PMC7016864

Abstract Article PDF–612K

Select item 68356667.

Gene Influence in the Effectiveness of Plant Sterols Treatment in Children: Pilot Interventional Study

Ismael San Mauro Martín, Elena Garicano Vilar, Sara Sanz Rojo, Luis Collado Yurrita, Eva Pérez Arruche, Esperanza Arce Delgado, Javier Andrés Blumenfeld Olivares

Nutrients. 2019 Oct; 11(10): 2538. Published online 2019 Oct 21. doi: 10.3390/nu11102538

PMCID:: PMC6835666

Abstract Article PDF–1.2M

Select item 66627568.

CETP, LIPC, and SCARB1 variants in individuals with extremely high high-density lipoprotein-cholesterol levels

Chan Joo Lee, Mun Su Park, Miso Kim, Soo-jin Ann, Jaeho Lee, Sungha Park, Seok-Min Kang, Yangsoo Jang, Ji Hyun Lee, Sang-Hak Lee

Sci Rep. 2019; 9: 10915. Published online 2019 Jul 29. doi: 10.1038/s41598-019-47456-2

PMCID:: PMC6662756

Abstract Article PDF–1.2M

Select item 65111519.

Pleiotropic association of LIPC variants with lipid and urinary 8-hydroxy deoxyguanosine levels in a Taiwanese population

Ming-Sheng Teng, Semon Wu, Lung-An Hsu, I-Shiang Tzeng, Hsin-Hua Chou, Cheng-Wen Su, Yu-Lin Ko

Lipids Health Dis. 2019; 18: 111. Published online 2019 May 10. doi: 10.1186/s12944-019-1057-9

PMCID:: PMC6511151

Abstract Article PDF–823K

Select item 640129510.

LDL triglycerides, hepatic lipase activity, and coronary artery disease: An epidemiologic and Mendelian randomization study

Günther Silbernagel, Hubert Scharnagl, Marcus E. Kleber, Graciela Delgado, Tatjana Stojakovic, Reijo Laaksonen, Jeanette Erdmann, Tuomo Rankinen, Claude Bouchard, Ulf Landmesser, Heribert Schunkert, Winfried März, Tanja B. Grammer

Atherosclerosis. Author manuscript; available in PMC 2020 Mar 1.

Published in final edited form as: Atherosclerosis. 2019 Mar; 282: 37–44. Published online 2018 Dec 28. doi: 10.1016/j.atherosclerosis.2018.12.024

PMCID:: PMC6401295

Abstract Article PDF–572K

Select item 619053811.

Association of LIPC -250G/A and -514C/T polymorphisms and hypertension: a systematic review and meta-analysis

Xingsheng Zhao, Yu Ren, Hui Li, Yun Wu

Lipids Health Dis. 2018; 17: 238. Published online 2018 Oct 15. doi: 10.1186/s12944-018-0884-4

PMCID:: PMC6190538

Abstract Article PDF–1.5M

Select item 573169512.

Human hepatic lipase overexpression in mice induces hepatic steatosis and obesity through promoting hepatic lipogenesis and white adipose tissue lipolysis and fatty acid uptake

Lídia Cedó, David Santos, Núria Roglans, Josep Julve, Victor Pallarès, Andrea Rivas-Urbina, Vicenta Llorente-Cortes, Joan Carles Laguna, Francisco Blanco-Vaca, Joan Carles Escolà-Gil

PLoS One. 2017; 12(12): e0189834. Published online 2017 Dec 15. doi: 10.1371/journal.pone.0189834

PMCID:: PMC5731695

Abstract Article PDF–1.2M

Select item 553161113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 520690014.

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

Cristen J Willer, Serena Sanna, Anne U Jackson, Angelo Scuteri, Lori L Bonnycastle, Robert Clarke, Simon C Heath, Nicholas J Timpson, Samer S Najjar, Heather M Stringham, James Strait, William L Duren, Andrea Maschio, Fabio Busonero, Antonella Mulas, Giuseppe Albai, Amy J Swift, Mario A Morken, Narisu Narisu, Derrick Bennett, Sarah Parish, Haiqing Shen, Pilar Galan, Pierre Meneton, Serge Hercberg, Diana Zelenika, Wei-Min Chen, Yun Li, Laura J Scott, Paul A Scheet, Jouko Sundvall, Richard M Watanabe, Ramaiah Nagaraja, Shah Ebrahim, Debbie A Lawlor, Yoav Ben-Shlomo, George Davey-Smith, Alan R Shuldiner, Rory Collins, Richard N Bergman, Manuela Uda, Jaakko Tuomilehto, Antonio Cao, Francis S Collins, Edward Lakatta, G Mark Lathrop, Michael Boehnke, David Schlessinger, Karen L Mohlke, Gonçalo R Abecasis

Nat Genet. Author manuscript; available in PMC 2017 Jan 3.

Published in final edited form as: Nat Genet. 2008 Feb; 40(2): 161–169. Published online 2008 Jan 13. doi: 10.1038/ng.76

PMCID:: PMC5206900

Abstract Article PDF–241K

Select item 511286915.

Insulin Clearance Is Associated with Hepatic Lipase Activity and Lipid and Adiposity Traits in Mexican Americans

Artak Labadzhyan, Jinrui Cui, Miklós Péterfy, Xiuqing Guo, Yii-Der I. Chen, Willa A. Hsueh, Jerome I. Rotter, Mark O. Goodarzi

PLoS One. 2016; 11(11): e0166263. Published online 2016 Nov 15. doi: 10.1371/journal.pone.0166263

PMCID:: PMC5112869

Abstract Article PDF–737K

Select item 506485616.

High-density lipoprotein subpopulation profiles in lipoprotein lipase and hepatic lipase deficiency

Mariko Tani, Katalin V. Horvath, Benoit Lamarche, Patrick Couture, John R. Burnett, Ernst J. Schaefer, Bela F. Asztalos

Atherosclerosis. Author manuscript; available in PMC 2017 Oct 1.

Published in final edited form as: Atherosclerosis. 2016 Oct; 253: 7–14. Published online 2016 Aug 20. doi: 10.1016/j.atherosclerosis.2016.08.014

PMCID:: PMC5064856

Abstract Article PDF–822K

Select item 462160317.

CETP/LPL/LIPC gene polymorphisms and susceptibility to age-related macular degeneration

Ya-Feng Wang, Yue Han, Rui Zhang, Li Qin, Ming-Xu Wang, Le Ma

Sci Rep. 2015; 5: 15711. Published online 2015 Oct 27. doi: 10.1038/srep15711

PMCID:: PMC4621603

Abstract Article PDF–1.0M

Select item 456893318.

Gender specific effect of LIPC C-514T polymorphism on obesity and relationship with plasma lipid levels in Chinese children

Hao Wang, Dandan Zhang, Jie Ling, Wenhui Lu, Shuai Zhang, Yimin Zhu, Maode Lai

J Cell Mol Med. 2015 Sep; 19(9): 2296–2306. Published online 2015 Aug 18. doi: 10.1111/jcmm.12663

PMCID:: PMC4568933

Abstract Article PDF–663K

Select item 456158119.

Regulation of hepatic lipase activity by sphingomyelin in plasma lipoproteins

Peng Yang, Papasani V. Subbaiah

Biochim Biophys Acta. Author manuscript; available in PMC 2016 Oct 1.

Published in final edited form as: Biochim Biophys Acta. 2015 Oct; 1851(10): 1327–1336. Published online 2015 Jul 18. doi: 10.1016/j.bbalip.2015.07.003

PMCID:: PMC4561581

Abstract Article PDF–2.3M

Select item 444211920.

Dietary Fat Intake Modifies the Effect of a Common Variant in the LIPC Gene on Changes in Serum Lipid Concentrations during a Long-Term Weight-Loss Intervention Trial

Min Xu, San San Ng, George A Bray, Donna H Ryan, Frank M Sacks, Guang Ning, Lu Qi

J Nutr. 2015 Jun; 145(6): 1289–1294. Published online 2015 Apr 29. doi: 10.3945/jn.115.212514

PMCID:: PMC4442119

Abstract Article PDF–602K

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