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Select item 91947441.

c‐Maf enforces cytokine production and promotes memory‐like responses in mouse and human type 2 innate lymphoid cells

Sara Trabanelli, Giuseppe Ercolano, Tania Wyss, Alejandra Gomez‐Cadena, Maryline Falquet, Daniela Cropp, Claire Imbratta, Marine M Leblond, Valentina Salvestrini, Antonio Curti, Olivier Adotevi, Camilla Jandus, Grégory Verdeil

EMBO J. 2022 Jun; 41(12): e109300. Published online 2022 Apr 25. doi: 10.15252/embj.2021109300

PMCID:: PMC9194744

Abstract Article PDF–1.5M

Select item 91324422.

Differential metabolic requirement governed by transcription factor c-Maf dictates innate γδT17 effector functionality in mice and humans

Xu Chen, Yihua Cai, Xiaoling Hu, Chuanlin Ding, Liqing He, Xiang Zhang, Fuxiang Chen, Jun Yan

Sci Adv. 2022 May; 8(21): eabm9120. Published online 2022 May 25. doi: 10.1126/sciadv.abm9120

PMCID:: PMC9132442

Abstract Article PDF–6.5M

Select item 89850763.

Transcription Factor c-Maf Promotes Immunoregulation of Programmed Cell Death 1–Expressed CD8⁺ T Cells in Multiple Sclerosis

Shusuke Koto, Norio Chihara, Ritsu Akatani, Hiroko Nakano, Atsushi Hara, Kenji Sekiguchi, Riki Matsumoto, Tatsushi Toda

Neurol Neuroimmunol Neuroinflamm. 2022 Jul; 9(4): e1166. Published online 2022 Apr 4. doi: 10.1212/NXI.0000000000001166

PMCID:: PMC8985076

Abstract Article PDF–721K

Select item 89614454.

Molecular Mechanisms Driving IL-10- Producing B Cells Functions: STAT3 and c-MAF as Underestimated Central Key Regulators?

Magalie Michée-Cospolite, Marina Boudigou, Alexis Grasseau, Quentin Simon, Olivier Mignen, Jacques-Olivier Pers, Divi Cornec, Laëtitia Le Pottier, Sophie Hillion

Front Immunol. 2022; 13: 818814. Published online 2022 Mar 10. doi: 10.3389/fimmu.2022.818814

PMCID:: PMC8961445

Abstract Article PDF–4.6M

Select item 87612175.

Association between WWOX/MAF variants and dementia-related neuropathologic endophenotypes

Adam J. Dugan, Peter T. Nelson, Yuriko Katsumata, Lincoln M. P. Shade, Merilee A. Teylan, Kevin L. Boehme, Shubhabrata Mukherjee, John S. K. Kauwe, Timothy J. Hohman, Julie A. Schneider, Alzheimer’s Disease Genetics Consortium, David W. Fardo

Neurobiol Aging. Author manuscript; available in PMC 2023 Mar 1.

Published in final edited form as: Neurobiol Aging. 2022 Mar; 111: 95–106. Published online 2021 Oct 29. doi: 10.1016/j.neurobiolaging.2021.10.011

PMCID:: PMC8761217

Abstract Article PDF–909K

Select item 83466946.

MAF Amplification and Adjuvant Clodronate Outcomes in Early-Stage Breast Cancer in NSABP B-34 and Potential Impact on Clinical Practice

Alexander H G Paterson, Peter C Lucas, Stewart J Anderson, Eleftherios P Mamounas, Adam Brufsky, Luis Baez-Diaz, Karen M King, Thomas Lad, André Robidoux, Melanie Finnigan, Miguel Sampayo, Juan Carlos Tercero, Joël Jean Mairet, Antonio C Wolff, Louis Fehrenbacher, Norman Wolmark, Roger R Gomis

JNCI Cancer Spectr. 2021 Aug; 5(4): pkab054. Published online 2021 May 28. doi: 10.1093/jncics/pkab054

PMCID:: PMC8346694

Abstract Article PDF–1.1M

Select item 83018097.

Loss of the MAF Transcription Factor in Laryngeal Squamous Cell Carcinoma

Joanna Janiszewska, Magdalena Bodnar, Julia Paczkowska, Adam Ustaszewski, Maciej J. Smialek, Lukasz Szylberg, Andrzej Marszalek, Katarzyna Kiwerska, Reidar Grenman, Krzysztof Szyfter, Malgorzata Wierzbicka, Maciej Giefing, Malgorzata Jarmuz-Szymczak

Biomolecules. 2021 Jul; 11(7): 1035. Published online 2021 Jul 15. doi: 10.3390/biom11071035

PMCID:: PMC8301809

Abstract Article PDF–3.3M

Select item 82890458.

Germinal Center T follicular helper (GC-Tfh) cell impairment in chronic HIV infection involves c-Maf signaling

Marita Chakhtoura, Mike Fang, Rafael Cubas, Margaret H. O’Connor, Carmen N. Nichols, Brian Richardson, Aarthi Talla, Susan Moir, Mark J. Cameron, Virginie Tardif, Elias K. Haddad

PLoS Pathog. 2021 Jul; 17(7): e1009732. Published online 2021 Jul 19. doi: 10.1371/journal.ppat.1009732

PMCID:: PMC8289045

Abstract Article PDF–4.5M

Select item 80604389.

Challenges and Limitations of Targeting the Keap1-Nrf2 Pathway for Neurotherapeutics: Bach1 De-Repression to the Rescue

Dmitry M. Hushpulian, Navneet Ammal Kaidery, Manuj Ahuja, Andrey A. Poloznikov, Sudarshana M. Sharma, Irina G. Gazaryan, Bobby Thomas

Front Aging Neurosci. 2021; 13: 673205. Published online 2021 Apr 8. doi: 10.3389/fnagi.2021.673205

PMCID:: PMC8060438

Abstract Article PDF–495K

Select item 803268910.

Aberrant TGF-β1 signaling activation by MAF underlies pathological lens growth in high myopia

Xiangjia Zhu, Yu Du, Dan Li, Jie Xu, Qingfeng Wu, Wenwen He, Keke Zhang, Jie Zhu, Linying Guo, Ming Qi, Ailin Liu, Jiao Qi, Guangyu Wang, Jiaqi Meng, Zhenglin Yang, Kang Zhang, Yi Lu

Nat Commun. 2021; 12: 2102. Published online 2021 Apr 8. doi: 10.1038/s41467-021-22041-2

Correction in:: Nat Commun. 2022; 13: 7834.

PMCID:: PMC8032689

Abstract Article PDF–6.9M

Select item 800904811.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 790560012.

Inhibition of the Otub1/c-Maf axis by the herbal acevaltrate induces myeloma cell apoptosis

Tong Sun, Yujia Xu, Zhuan Xu, Biyin Cao, Zubin Zhang, Qi Wang, Yan Kong, Xinliang Mao

Cell Commun Signal. 2021; 19: 24. Published online 2021 Feb 24. doi: 10.1186/s12964-020-00676-w

PMCID:: PMC7905600

Abstract Article PDF–3.5M

Select item 770833013.

MAFB and MAF Transcription Factors as Macrophage Checkpoints for COVID-19 Severity

Miguel A. Vega, Miriam Simón-Fuentes, Arturo González de la Aleja, Concha Nieto, María Colmenares, Cristina Herrero, Ángeles Domínguez-Soto, Ángel L. Corbí

Front Immunol. 2020; 11: 603507. Published online 2020 Nov 18. doi: 10.3389/fimmu.2020.603507

PMCID:: PMC7708330

Abstract Article PDF–1.3M

Select item 746857814.

Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis

Xue-han Chen, Yu-jia Xu, Xiao-ge Wang, Peng Lin, Bi-yin Cao, Yuan-ying Zeng, Qi Wang, Zu-bin Zhang, Xin-liang Mao, Tie Zhang

Acta Pharmacol Sin. 2019 Dec; 40(12): 1568–1577. Published online 2019 Jun 13. doi: 10.1038/s41401-019-0249-1

PMCID:: PMC7468578

Abstract Article PDF–2.4M

Select item 702912315.

The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival

Yuanming He, Siyu Wang, Jiefei Tong, Shuoyi Jiang, Ye Yang, Zubin Zhang, Yujia Xu, Yuanying Zeng, Biyin Cao, Michael F. Moran, Xinliang Mao

J Biol Chem. 2020 Feb 14; 295(7): 2084–2096. Published online 2019 Dec 10. doi: 10.1074/jbc.RA119.010724

PMCID:: PMC7029123

Abstract Article PDF–3.6M

Select item 682431116.

PD-1^hiCXCR5^– T peripheral helper cells promote B cell responses in lupus via MAF and IL-21

Alexandra V. Bocharnikov, Joshua Keegan, Vanessa S. Wacleche, Ye Cao, Chamith Y. Fonseka, Guoxing Wang, Eric S. Muise, Kelvin X. Zhang, Arnon Arazi, Gregory Keras, Zhihan J. Li, Yujie Qu, Michael F. Gurish, Accelerating Medicines Partnership (AMP) RA/SLE Network, Michelle Petri, Jill P. Buyon, Chaim Putterman, David Wofsy, Judith A. James, Joel M. Guthridge, Betty Diamond, Jennifer H. Anolik, Matthew F. Mackey, Stephen E. Alves, Peter A. Nigrovic, Karen H. Costenbader, Michael B. Brenner, James A. Lederer, Deepak A. Rao

JCI Insight. 2019 Oct 17; 4(20): e130062. Published online 2019 Oct 17. doi: 10.1172/jci.insight.130062

PMCID:: PMC6824311

Abstract Article PDF–5.8M

Select item 679814517.

Maf expression in human macrophages and lymph node sinus macrophages in patients with esophageal cancer

Hiroto Takeya, Koji Ohnishi, Takuya Shiota, Yoichi Saito, Yukio Fujiwara, Taisuke Yagi, Yuki Kiyozumi, Yoshifumi Baba, Naoya Yoshida, Kenichi Asano, Masato Tanaka, Hideo Baba, Yoshihiro Komohara

J Clin Exp Hematop. 2019 Sep; 59(3): 112–118. Published online 2019 Sep 30. doi: 10.3960/jslrt.19002

PMCID:: PMC6798145

Abstract Article PDF–2.3M

Select item 667613718.

Immunohistochemistry for identification of CCND1, NSD2, and MAF gene rearrangements in plasma cell myeloma

Takayuki Murase, Masaki Ri, Tomoko Narita, Keiichiro Fujii, Ayako Masaki, Shinsuke Iida, Hiroshi Inagaki

Cancer Sci. 2019 Aug; 110(8): 2600–2606. Published online 2019 Jul 11. doi: 10.1111/cas.14109

PMCID:: PMC6676137

Abstract Article PDF–874K

Select item 640256019.

Immunoregulatory and tissue-residency programs modulated by c-MAF in human T_H17 cells

Dominik Aschenbrenner, Mathilde Foglierini, David Jarrossay, Dan Hu, Howard L. Weiner, Vijay K. Kuchroo, Antonio Lanzavecchia, Samuele Notarbartolo, Federica Sallusto

Nat Immunol. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Nat Immunol. 2018 Oct; 19(10): 1126–1136. Published online 2018 Sep 10. doi: 10.1038/s41590-018-0200-5

Correction in:: Nat Immunol. 2018 Nov 17

PMCID:: PMC6402560

Abstract Article PDF–2.6M

Select item 591246820.

The transmembrane protein TMEPAI induces myeloma cell apoptosis by promoting degradation of the c-Maf transcription factor

Yanyun Du, Yan Liu, Yujia Xu, Jiaxiang Juan, Zubin Zhang, Zhuan Xu, Biyin Cao, Qi Wang, Yuanying Zeng, Xinliang Mao

J Biol Chem. 2018 Apr 20; 293(16): 5847–5859. Published online 2018 Feb 21. doi: 10.1074/jbc.RA117.000972

PMCID:: PMC5912468

Abstract Article PDF–3.3M

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