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Select item 108474241.

Heat shock protein gp96 drives natural killer cell maturation and anti-tumor immunity by counteracting Trim28 to stabilize Eomes

Yuxiu Xu, Xin Li, Fang Cheng, Bao Zhao, Min Fang, Zihai Li, Songdong Meng

Nat Commun. 2024; 15: 1106. Published online 2024 Feb 6. doi: 10.1038/s41467-024-45426-5

PMCID:: PMC10847424

Abstract Article PDF–6.1M

Select item 103939962.

TRIM28 modulates nuclear receptor signaling to regulate uterine function

Rong Li, Tianyuan Wang, Ryan M. Marquardt, John P. Lydon, San-Pin Wu, Francesco J. DeMayo

Nat Commun. 2023; 14: 4605. Published online 2023 Aug 1. doi: 10.1038/s41467-023-40395-7

PMCID:: PMC10393996

Abstract Article PDF–11M

Select item 102909893.

TRIM28 promotes the escape of gastric cancer cells from immune surveillance by increasing PD-L1 abundance

Xiaoxiao Ma, Shuqin Jia, Gangjian Wang, Min Liang, Ting Guo, Hong Du, Sisi Li, Xiaomei Li, Longtao Huangfu, Jianping Guo, Xiaofang Xing, Jiafu Ji

Signal Transduct Target Ther. 2023; 8: 246. Published online 2023 Jun 26. doi: 10.1038/s41392-023-01450-3

PMCID:: PMC10290989

Abstract Article PDF–5.5M

Select item 102312584.

Mitochondrial Glycerol-3-Phosphate Dehydrogenase Restricts HBV Replication via the TRIM28-Mediated Degradation of HBx

Canyu Liu, Kaitao Zhao, Yingshan Chen, Yongxuan Yao, Jielin Tang, Jingjing Wang, Chonghui Xu, Qi Yang, Yi Zheng, Yifei Yuan, Hao Sun, Yongli Zhang, Yuan Zhou, Jizheng Chen, Yun Wang, Chunchen Wu, Rongjuan Pei, Xinwen Chen

J Virol. 2023 May; 97(5): e00580-23. Published online 2023 May 11. doi: 10.1128/jvi.00580-23

PMCID:: PMC10231258

Abstract Article PDF–3.9M

Select item 101415225.

TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy

Tanjing Song, Suli Lv, Xianyun Ma, Xuefeng Zhao, Li Fan, Qingli Zou, Neng Li, Yingying Yan, Wen Zhang, Lidong Sun

J Biol Chem. 2023 May; 299(5): 104621. Published online 2023 Mar 18. doi: 10.1016/j.jbc.2023.104621

PMCID:: PMC10141522

Abstract Article PDF–2.5M

Select item 101227116.

TRIM28 promotes luminal cell plasticity in a mouse model of prostate cancer

Ashutosh S. Yende, Emily C. Williams, Andrew Pletcher, Alexandra Helfand, Helen Ibeawuchi, Tanya M. North, Patricia S. Latham, Anelia Horvath, Maho Shibata

Oncogene. Author manuscript; available in PMC 2023 Apr 23.

Published in final edited form as: Oncogene. 2023 Apr; 42(17): 1347–1359. Published online 2023 Mar 8. doi: 10.1038/s41388-023-02655-0

PMCID:: PMC10122711

Abstract Article PDF–4.4M

Select item 95449567.

MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice

Samina Kazi, Julio M. Castañeda, Audrey Savolainen, Yiding Xu, Ning Liu, Huanyu Qiao, Ramiro Ramirez‐Solis, Kaori Nozawa, Zhifeng Yu, Martin M. Matzuk, Renata Prunskaite‐Hyyryläinen

FASEB J. 2022 Sep; 36(9): e22479. Published online 2022 Aug 3. doi: 10.1096/fj.202101168RR

PMCID:: PMC9544956

Abstract Article PDF–9.8M

Select item 94998728.

Independent phenotypic plasticity axes define distinct obesity sub-types

Chih-Hsiang Yang, Luca Fagnocchi, Stefanos Apostle, Vanessa Wegert, Salvador Casaní-Galdón, Kathrin Landgraf, Ilaria Panzeri, Erez Dror, Steffen Heyne, Till Wörpel, Darrell P. Chandler, Di Lu, Tao Yang, Elizabeth Gibbons, Rita Guerreiro, Jose Bras, Martin Thomasen, Louise G. Grunnet, Allan A. Vaag, Linn Gillberg, Elin Grundberg, Ana Conesa, Antje Körner, PERMUTE, J. Andrew Pospisilik

Nat Metab. 2022; 4(9): 1150–1165. Published online 2022 Sep 12. doi: 10.1038/s42255-022-00629-2

PMCID:: PMC9499872

Abstract Article PDF–21M

Select item 94819339.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 935588010.

Hijacking of transcriptional condensates by endogenous retroviruses

Vahid Asimi, Abhishek Sampath Kumar, Henri Niskanen, Christina Riemenschneider, Sara Hetzel, Julian Naderi, Nina Fasching, Niko Popitsch, Manyu Du, Helene Kretzmer, Zachary D. Smith, Raha Weigert, Maria Walther, Sainath Mamde, David Meierhofer, Lars Wittler, René Buschow, Bernd Timmermann, Ibrahim I. Cisse, Stefan L. Ameres, Alexander Meissner, Denes Hnisz

Nat Genet. 2022; 54(8): 1238–1247. Published online 2022 Jul 21. doi: 10.1038/s41588-022-01132-w

PMCID:: PMC9355880

Abstract Article PDF–27M

Select item 933804011.

TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway

Moïra Rossitto, Stephanie Déjardin, Chris M. Rands, Stephanie Le Gras, Roberta Migale, Mahmoud-Reza Rafiee, Yasmine Neirijnck, Alain Pruvost, Anvi Laetitia Nguyen, Guillaume Bossis, Florence Cammas, Lionel Le Gallic, Dagmar Wilhelm, Robin Lovell-Badge, Brigitte Boizet-Bonhoure, Serge Nef, Francis Poulat

Nat Commun. 2022; 13: 4412. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32061-1

PMCID:: PMC9338040

Abstract Article PDF–11M

Select item 926452612.

KAP1 phosphorylation promotes the survival of neural stem cells after ischemia/reperfusion by maintaining the stability of PCNA

Wan Wang, Tianqing Yan, Xinjian Guo, Heng Cai, Chang Liang, Linyan Huang, Yanling Wang, Ping Ma, Suhua Qi

Stem Cell Res Ther. 2022; 13: 290. Published online 2022 Jul 7. doi: 10.1186/s13287-022-02962-5

PMCID:: PMC9264526

Abstract Article PDF–7.0M

Select item 871379413.

Transcriptional network orchestrating regional patterning of cortical progenitors

Athéna R. Ypsilanti, Kartik Pattabiraman, Rinaldo Catta-Preta, Olga Golonzhka, Susan Lindtner, Ke Tang, Ian R. Jones, Armen Abnousi, Ivan Juric, Ming Hu, Yin Shen, Diane E. Dickel, Axel Visel, Len A. Pennacchio, Michael Hawrylycz, Carol L. Thompson, Hongkui Zeng, Iros Barozzi, Alex S. Nord, John L. Rubenstein

Proc Natl Acad Sci U S A. 2021 Dec 21; 118(51): e2024795118. Published online 2021 Dec 17. doi: 10.1073/pnas.2024795118

PMCID:: PMC8713794

Abstract Article PDF–3.1M

Select item 845650714.

Characterization of interaction between Trim28 and YY1 in silencing proviral DNA of Moloney murine leukemia virus

Andreia Lee, Oya CingÖz, Yosef Sabo, Stephen P. Goff

Virology. Author manuscript; available in PMC 2021 Sep 22.

Published in final edited form as: Virology. 2018 Mar; 516: 165–175. doi: 10.1016/j.virol.2018.01.012

PMCID:: PMC8456507

Abstract Article PDF–827K

Select item 835294515.

TRIM28 SUMOylates and stabilizes NLRP3 to facilitate inflammasome activation

Ying Qin, Qi Li, Wenbo Liang, Rongzhen Yan, Li Tong, Mutian Jia, Chunyuan Zhao, Wei Zhao

Nat Commun. 2021; 12: 4794. Published online 2021 Aug 9. doi: 10.1038/s41467-021-25033-4

PMCID:: PMC8352945

Abstract Article PDF–2.9M

Select item 828796116.

Phosphorylation of the HP1β hinge region sequesters KAP1 in heterochromatin and promotes the exit from naïve pluripotency

Weihua Qin, Enes Ugur, Christopher B Mulholland, Sebastian Bultmann, Irina Solovei, Miha Modic, Martha Smets, Michael Wierer, Ignasi Forné, Axel Imhof, M Cristina Cardoso, Heinrich Leonhardt

Nucleic Acids Res. 2021 Jul 21; 49(13): 7406–7423. Published online 2021 Jul 2. doi: 10.1093/nar/gkab548

PMCID:: PMC8287961

Abstract Article PDF–5.6M

Select item 809085717.

Activation of endogenous retroviruses during brain development causes an inflammatory response

Marie E Jönsson, Raquel Garza, Yogita Sharma, Rebecca Petri, Erik Södersten, Jenny G Johansson, Pia A Johansson, Diahann AM Atacho, Karolina Pircs, Sofia Madsen, David Yudovich, Ramprasad Ramakrishnan, Johan Holmberg, Jonas Larsson, Patric Jern, Johan Jakobsson

EMBO J. 2021 May 3; 40(9): e106423. Published online 2021 Mar 1. doi: 10.15252/embj.2020106423

PMCID:: PMC8090857

Abstract Article PDF–4.0M

Select item 796729018.

Mapping of the contraction-induced phosphoproteome identifies TRIM28 as a significant regulator of skeletal muscle size and function

Nathaniel D. Steinert, Gregory K. Potts, Gary M. Wilson, Amelia M. Klamen, Kuan-Hung Lin, Jake B. Hermanson, Rachel M. McNally, Joshua J. Coon, Troy A. Hornberger

Cell Rep. Author manuscript; available in PMC 2021 Mar 17.

Published in final edited form as: Cell Rep. 2021 Mar 2; 34(9): 108796. doi: 10.1016/j.celrep.2021.108796

PMCID:: PMC7967290

Abstract Article PDF–2.9M

Select item 793877019.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 786228720.

Kap1 regulates the self-renewal of embryonic stem cells and cellular reprogramming by modulating Oct4 protein stability

Eun Kyoung Do, Hye Ji Moon, Kyung Taek Kang, Jung Won Yoon, Ye Seul Kim, Jeong Kon Seo, Jae Ho Kim

Cell Death Differ. 2021 Feb; 28(2): 685–699. Published online 2020 Sep 7. doi: 10.1038/s41418-020-00613-x

PMCID:: PMC7862287

Abstract Article PDF–3.7M

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