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Items: 1 to 20 of 28

1.
De novo SIX2 activation in human kidneys treated with neonatal kidney stem/progenitor cells
Fanny Oliveira Arcolino, Sarah Hosgood, Sara Akalay, Nina Jordan, Jean Herman, Tegwen Elliott, Koenraad Veys, Kurt Vermeire, Ben Sprangers, Michael Nicholson, Lambertus van den Heuvel, Elena Levtchenko
Am J Transplant. 2022 Dec; 22(12): 2791–2803. Published online 2022 Aug 11. doi: 10.1111/ajt.17164
PMCID:
PMC10087644
AbstractArticlePDF–7.1M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
A New Frontonasal Dysplasia Syndrome Associated with Deletion of the SIX2 Gene
Robert B. Hufnagel, Sarah L. Zimmerman, Laura A. Krueger, Patricia L. Bender, Zubair M. Ahmed, Howard M. Saal
Am J Med Genet A. Author manuscript; available in PMC 2021 May 10.
Published in final edited form as: Am J Med Genet A. 2016 Feb; 170A(2): 487–491. Published online 2015 Nov 18. doi: 10.1002/ajmg.a.37441
PMCID:
PMC8108007
AbstractArticlePDF–646K
4.
A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition
Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington
Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331
PMCID:
PMC8045932
AbstractArticlePDF–1.9M
5.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
6.
SIX2 Regulates Human β Cell Differentiation from Stem Cells and Functional Maturation In Vitro
Leonardo Velazco-Cruz, Madeleine M. Goedegebuure, Kristina G. Maxwell, Punn Augsornworawat, Nathaniel J. Hogrebe, Jeffrey R. Millman
Cell Rep. Author manuscript; available in PMC 2020 Jun 19.
Published in final edited form as: Cell Rep. 2020 May 26; 31(8): 107687. doi: 10.1016/j.celrep.2020.107687
PMCID:
PMC7304247
AbstractArticlePDF–1.8M
7.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
8.
A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-κB
Zixu Liu, Katrina B. Mar, Natasha W. Hanners, Sofya S. Perelman, Mohammed Kanchwala, Chao Xing, John W. Schoggins, Neal M. Alto
Nature. Author manuscript; available in PMC 2019 Oct 24.
Published in final edited form as: Nature. 2019 Apr; 568(7751): 249–253. Published online 2019 Mar 20. doi: 10.1038/s41586-019-1041-6
PMCID:
PMC6812682
AbstractArticlePDF–4.2M
9.
Transcription factor Six2 induces a stem cell‐like phenotype in renal cell carcinoma cells
Na Cheng, Hongjuan Li, Yan Han, Shuzhen Sun
FEBS Open Bio. 2019 Oct; 9(10): 1808–1816. Published online 2019 Sep 19. doi: 10.1002/2211-5463.12721
PMCID:
PMC6768107
AbstractArticlePDF–4.0M
10.
Six2 mediates late-stage metastasis via direct regulation of Sox2 and induction of a cancer stem cell program
Michael U.J. Oliphant, Melanie Y. Vincent, Matthew D. Galbraith, Ahwan Pandey, Vadym Zaberezhnyy, Pratyaydipta Rudra, Katherine R. Johnson, James C. Costello, Debashis Ghosh, James DeGregori, Joaquin M. Espinosa, Heide L. Ford
Cancer Res. Author manuscript; available in PMC 2020 Feb 15.
Published in final edited form as: Cancer Res. 2019 Feb 15; 79(4): 720–734. Published online 2019 Jan 3. doi: 10.1158/0008-5472.CAN-18-1791
PMCID:
PMC6586234
AbstractArticlePDF–2.4M
11.
H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination in sister chromatids
Kyosuke Nakamura, Giulia Saredi, Jordan R. Becker, Benjamin M. Foster, Nhuong V. Nguyen, Tracey Beyer, Laura C. Cesa, Peter A. Faull, Saulius Lukauskas, Thomas Frimurer, J. Ross Chapman, Till Bartke, Anja Groth
Nat Cell Biol. Author manuscript; available in PMC 2019 Aug 25.
Published in final edited form as: Nat Cell Biol. 2019 Mar; 21(3): 311–318. Published online 2019 Feb 25. doi: 10.1038/s41556-019-0282-9
PMCID:
PMC6420097
ArticlePDF–1.7M
12.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
13.
TβRII Regulates the Proliferation of Metanephric Mesenchyme Cells through Six2 In Vitro
Zhaomin Mao, Zhongshi Lyu, Liyuan Huang, Qin Zhou, Yaguang Weng
Int J Mol Sci. 2017 Apr; 18(4): 853. Published online 2017 Apr 18. doi: 10.3390/ijms18040853
PMCID:
PMC5412437
AbstractArticlePDF–11M
14.
SIX2 haploinsufficiency causes conductive hearing loss with ptosis in humans
Jing Guan, Dayong Wang, Wenjian Cao, Yali Zhao, Renqian Du, Hu Yuan, Qiong Liu, Lan Lan, Liang Zong, Ju Yang, Zifang Yin, Bing Han, Feng Zhang, Qiuju Wang
J Hum Genet. 2016 Nov; 61(11): 917–922. Published online 2016 Jul 7. doi: 10.1038/jhg.2016.86
PMCID:
PMC5411491
AbstractArticlePDF–2.3M
15.
The YAP1/SIX2 axis is required for DDX3-mediated tumor aggressiveness and cetuximab resistance in KRAS-wild-type colorectal cancer
De-Wei Wu, Po-Lin Lin, Lee Wang, Chi-Chou Huang, Huei Lee
Theranostics. 2017; 7(5): 1114–1132. Published online 2017 Feb 27. doi: 10.7150/thno.18175
PMCID:
PMC5399580
AbstractArticlePDF–3.7M
16.
The expression profile and clinic significance of the SIX family in non-small cell lung cancer
Qian Liu, Anping Li, Yijun Tian, Yu Liu, Tengfei Li, Cuntai Zhang, Jennifer D. Wu, Xinwei Han, Kongming Wu
J Hematol Oncol. 2016; 9: 119. Published online 2016 Nov 8. doi: 10.1186/s13045-016-0339-1
PMCID:
PMC5100270
AbstractArticlePDF–4.9M
17.
Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor
Sarah Daakour, Leon Juvenal Hajingabo, Despoina Kerselidou, Aurelie Devresse, Richard Kettmann, Nicolas Simonis, Franck Dequiedt, Jean-Claude Twizere
BMC Cancer. 2016; 16: 335. Published online 2016 May 26. doi: 10.1186/s12885-016-2374-2
PMCID:
PMC4882867
AbstractArticlePDF–1.8M
18.
Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors
Amy L. Walz, Ariadne Ooms, Samantha Gadd, Daniela S. Gerhard, Malcolm A. Smith, Jamie M. Guidry Auvil, Daoud Meerzaman, Qing-Rong Chen, Chih Hao Hsu, Chunhua Yan, Cu Nguyen, Ying Hu, Reanne Bowlby, Denise Brooks, Yussanne Ma, Andrew J. Mungall, Richard A. Moore, Jacqueline Schein, Marco A. Marra, Vicki Huff, Jeffrey S. Dome, Yueh-Yun Chi, Charles G. Mullighan, Jing Ma, David A. Wheeler, Oliver A. Hampton, Nadereh Jafari, Nicole Ross, Julie M. Gastier-Foster, Elizabeth J. Perlman
Cancer Cell. Author manuscript; available in PMC 2016 Mar 21.
Published in final edited form as: Cancer Cell. 2015 Feb 9; 27(2): 286–297. doi: 10.1016/j.ccell.2015.01.003
Correction in:
volume 27 on page 426
PMCID:
PMC4800737
AbstractArticlePDF–510K
19.
Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators
Lori L. O'Brien, Qiuyu Guo, YoungJin Lee, Tracy Tran, Jean-Denis Benazet, Peter H. Whitney, Anton Valouev, Andrew P. McMahon
Development. 2016 Feb 15; 143(4): 595–608. doi: 10.1242/dev.127175
PMCID:
PMC4760318
AbstractArticle
20.
Genome-Wide Association Meta-analysis Identifies Novel Variants Associated With Fasting Plasma Glucose in East Asians
Joo-Yeon Hwang, Xueling Sim, Ying Wu, Jun Liang, Yasuharu Tabara, Cheng Hu, Kazuo Hara, Claudia H.T. Tam, Qiuyin Cai, Qi Zhao, Sunha Jee, Fumihiko Takeuchi, Min Jin Go, Rick Twee Hee Ong, Takayoshi Ohkubo, Young Jin Kim, Rong Zhang, Toshimasa Yamauchi, Wing Yee So, Jirong Long, Dongfeng Gu, Nanette R. Lee, Soriul Kim, Tomohiro Katsuya, Ji Hee Oh, Jianjun Liu, Satoshi Umemura, Yeon-Jung Kim, Feng Jiang, Shiro Maeda, Juliana C.N. Chan, Wei Lu, James E. Hixson, Linda S. Adair, Keum Ji Jung, Toru Nabika, Jae-Bum Bae, Mi Hee Lee, Mark Seielstad, Terri L. Young, Yik Ying Teo, Yoshikuni Kita, Naoyuki Takashima, Haruhiko Osawa, So-Hyun Lee, Min-Ho Shin, Dong Hoon Shin, Bo Youl Choi, Jiajun Shi, Yu-Tang Gao, Yong-Bing Xiang, Wei Zheng, Norihiro Kato, Miwuk Yoon, Jiang He, Xiao Ou Shu, Ronald C.W. Ma, Takashi Kadowaki, Weiping Jia, Tetsuro Miki, Lu Qi, E Shyong Tai, Karen L. Mohlke, Bok-Ghee Han, Yoon Shin Cho, Bong-Jo Kim
Diabetes. 2015 Jan; 64(1): 291–298. Published online 2014 Sep 3. doi: 10.2337/db14-0563
PMCID:
PMC4274808
AbstractArticlePDF–1.0M

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