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Items: 1 to 20 of 21

1.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
2.
A POINT MUTATION CREATING A 3′ SPLICE SITE IN C8A IS A PREDOMINANT CAUSE OF C8α-γ DEFICIENCY IN AFRICAN AMERICANS
Peter Densen, Laynez Ackermann, Leslie Saucedo, Julio E. Figueroa, II, Zhi-hai Si, Conrad Martin Stoltzfus
J Immunol. Author manuscript; available in PMC 2021 Sep 15.
Published in final edited form as: J Immunol. 2020 Sep 15; 205(6): 1535–1539. Published online 2020 Aug 7. doi: 10.4049/jimmunol.2000272
PMCID:
PMC7484158
AbstractArticlePDF–1.5M
3.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
4.
CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers
Anaïs Menny, Marina Serna, Courtney M. Boyd, Scott Gardner, Agnel Praveen Joseph, B. Paul Morgan, Maya Topf, Nicholas J. Brooks, Doryen Bubeck
Nat Commun. 2018; 9: 5316. Published online 2018 Dec 14. doi: 10.1038/s41467-018-07653-5
PMCID:
PMC6294249
AbstractArticlePDF–3.4M
5.
Comprehensive Proteoform Characterization of Plasma Complement Component C8αβγ by Hybrid Mass Spectrometry Approaches
Vojtech Franc, Jing Zhu, Albert J. R. Heck
J Am Soc Mass Spectrom. 2018; 29(6): 1099–1110. Published online 2018 Mar 12. doi: 10.1007/s13361-018-1901-6
PMCID:
PMC6003997
AbstractArticlePDF–2.4M
6.
Association between the SERPING1 gene and age-related macular degeneration: a two-stage case–control study
Sarah Ennis, Catherine Jomary, Robert Mullins, Angela Cree, Xiaoli Chen, Alex MacLeod, Stephen Jones, Prof Andrew Collins, Prof Edwin Stone, Prof Andrew Lotery
Lancet. Author manuscript; available in PMC 2018 Jun 1.
Published in final edited form as: Lancet. 2008 Nov 22; 372(9652): 1828–1834. Published online 2008 Oct 6. doi: 10.1016/S0140-6736(08)61348-3
PMCID:
PMC5983350
AbstractArticlePDF–675K
7.
Membrane Pore Formation by Human Complement: Functional Importance of the Transmembrane β-Hairpin (TMH) Segments of C8α and C9
Mitch H. Weiland, Yu Qian, James M. Sodetz
Mol Immunol. Author manuscript; available in PMC 2015 Feb 1.
Published in final edited form as: Mol Immunol. 2014 Feb; 57(2): 10.1016/j.molimm.2013.10.007. Published online 2013 Nov 12. doi: 10.1016/j.molimm.2013.10.007
PMCID:
PMC3856643
AbstractArticlePDF–2.3M
8.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake
Proteomics. Author manuscript; available in PMC 2014 May 1.
Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561
PMCID:
PMC3773505
AbstractArticlePDF–630K
9.
Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5b6 and sC5b9
Michael A. Hadders, Doryen Bubeck, Pietro Roversi, Svetlana Hakobyan, Federico Forneris, B. Paul Morgan, Michael K. Pangburn, Oscar Llorca, Susan M. Lea, Piet Gros
Cell Rep. Author manuscript; available in PMC 2012 Mar 29.
Published in final edited form as: Cell Rep. 2012 Mar 29; 1(3): 200–207. doi: 10.1016/j.celrep.2012.02.003
PMCID:
PMC3314296
AbstractArticlePDF–1.4M
10.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
11.
Risk of Meningioma and Common Variation in Genes related to Innate Immunity
Preetha Rajaraman, Alina V. Brenner, Gila Neta, Ruth Pfeiffer, Sophia S. Wang, Meredith Yeager, Gilles Thomas, Howard A. Fine, Martha S. Linet, Nathaniel Rothman, Stephen J. Chanock, Peter D. Inskip
Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2011 Sep 7.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 May; 19(5): 1356–1361. Published online 2010 Apr 20. doi: 10.1158/1055-9965.EPI-09-1151
PMCID:
PMC3169167
AbstractArticlePDF–61K
12.
Mapping the Intermedilysin-Human CD59 Receptor Interface Reveals a Deep Correspondence with the Binding Site on CD59 for Complement Binding Proteins C8α and C9
Stephanie E. Wickham, Eileen M. Hotze, Allison J. Farrand, Galina Polekhina, Tracy L. Nero, Stephen Tomlinson, Michael W. Parker, Rodney K. Tweten
J Biol Chem. 2011 Jun 10; 286(23): 20952–20962. Published online 2011 Apr 20. doi: 10.1074/jbc.M111.237446
PMCID:
PMC3121471
AbstractArticlePDF–1.0M
13.
Polymorphisms in innate immunity genes and risk of childhood leukemia
Sohee Han, Qing Lan, Ae Kyung Park, Kyoung-Mu Lee, Sue K. Park, Hyo Seop Ahn, Hee Young Shin, Hyoung Jin Kang, Hong Hoe Koo, Jong Jin Seo, Ji Eun Choi, Yoon-Ok Ahn, Stephen J. Chanock, Ho Kim, Nathaniel Rothman, Daehee Kang
Hum Immunol. Author manuscript; available in PMC 2010 Nov 2.
Published in final edited form as: Hum Immunol. 2010 Jul; 71(7): 727–730. Published online 2010 May 16. doi: 10.1016/j.humimm.2010.04.004
PMCID:
PMC2967770
AbstractArticlePDF–306K
14.
Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study
Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators
Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452
PMCID:
PMC2945168
AbstractArticlePDF–153K
15.
Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score
Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl
Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159
Correction in:
Mol Med. 2012; 18(1): 729.
PMCID:
PMC2896464
AbstractArticlePDF–2.4M
16.
Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip
Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani
Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014
PMCID:
PMC2775832
AbstractArticlePDF–2.8M
17.
Common Variation in Genes Related to Innate Immunity and Risk of Adult Glioma
Preetha Rajaraman, Alina V. Brenner, Mary Ann Butler, Sophia S. Wang, Ruth M. Pfeiffer, Avima M. Ruder, Martha S. Linet, Meredith Yeager, Zhaoming Wang, Nick Orr, Howard A. Fine, Deukwoo Kwon, Gilles Thomas, Nathaniel Rothman, Peter D. Inskip, Stephen J. Chanock
Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2010 May 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2009 May; 18(5): 1651–1658. doi: 10.1158/1055-9965.EPI-08-1041
PMCID:
PMC2771723
AbstractArticlePDF–392K
18.
Crystal Structure of the MACPF Domain of Human Complement Protein C8α in Complex with the C8γ Subunit
Daniel J. Slade, Leslie L. Lovelace, Maksymilian Chruszcz, Wladek Minor, Lukasz Lebioda, James M. Sodetz
J Mol Biol. Author manuscript; available in PMC 2009 May 30.
Published in final edited form as: J Mol Biol. 2008 May 30; 379(2): 331–342. Published online 2008 Apr 3. doi: 10.1016/j.jmb.2008.03.061
PMCID:
PMC2443722
AbstractArticlePDF–2.2M
19.
Human Plasma N-Glycoproteome Analysis by Immunoaffinity Subtraction, Hydrazide Chemistry, and Mass Spectrometry
Tao Liu, Wei-Jun Qian, Marina A. Gritsenko, David G. Camp, II, Matthew E. Monroe, Ronald J. Moore, Richard D. Smith
J Proteome Res. Author manuscript; available in PMC 2007 Apr 10.
Published in final edited form as: J Proteome Res. 2005; 4(6): 2070–2080. doi: 10.1021/pr0502065
PMCID:
PMC1850943
AbstractArticlePDF–626K
20.
Recurrent meningococcal infections associated with a functional deficiency of the C8 component of human complement.
N Matthews, J M Stark, P S Harper, J Doran, D M Jones
Clin Exp Immunol. 1980 Jan; 39(1): 53–59.
PMCID:
PMC1537948
SummaryPage BrowsePDF–991K

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